• Published on: Jan 20, 2021
  • 1 minute read
  • By: Dr Rajan Choudhary

MRNA Vaccines – Uses Beyond COVID

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mRNA vaccines – uses beyond COVID

Last year we estimated it would take over a year for a vaccine against COVID to be approved, with vaccinations expected by spring 2021. Incredibly we have managed to meet this prediction, and by the start of January over 42 million doses have been administered in 51 countries. What is even more astounding is that two of the approved vaccines use a completely new vaccination method never used before. mRNA vaccines can be used to easily deliver a variety of different vaccines by changing the mRNA inside the vaccine capsule, and its benefits may not be limited to just infections.

A recent publication in NATURE has demonstrated the use of mRNA vaccines against auto-immune diseases such as multiple sclerosis. MS is an autoimmune condition in which the protective lining of nerves is destroyed by the body’s immune system, significantly slowing down or altering nerve impulse propagation. This leads to symptoms such as fatigue, vision problems, numbness, tingling, aberrant pain, muscle spasms and weakness.

The study looked at introducing antigen-specific tolerance in mice models of MS. This was achieved by activating anti-inflammatory white blood cells. Normally vaccines activate inflammatory white cells to produce a response but altered mRNA with one specific change to its base structure induces and activates anti-inflammatory cells instead.

Furthermore, this anti-inflammatory response is specific to cells that are activated by and attack the body’s nerve cells, thereby delivering a targeted response and not affecting the immune response against infections or cancer. Global immunosuppression is a common side effect of steroids and chemotherapy agents that are normally used to treat auto-immune conditions, and mRNA vaccines may avoid this side effect altogether.

A further advantage is its versatility. This has been demonstrated against multiple sclerosis, but changing the mRNA delivered by the vaccine, it may prove beneficial in far more auto-immune conditions. Of course, we have to emphasize this was an animal study and human trials are unlikely to happen in the next few years, but this study nicely demonstrates how the impact of the COVID pandemic may already be providing beneficial gains for the future.

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Simple Habits to Avoid High Cholesterol

Simple Habits to Avoid High Cholesterol

High cholesterol is one of the leading causes of heart disease and stroke worldwide. In India, rising cholesterol levels are becoming more common due to sedentary lifestyles, unhealthy food habits, and stress. But the good news is—you can prevent high cholesterol naturally with a few simple habits.

In this blog, we’ll explore easy, everyday steps you can take to keep your cholesterol levels in check and protect your heart.

 

What Is Cholesterol?

Cholesterol is a fatty substance found in your blood. While your body needs some cholesterol to build cells and hormones, too much of the wrong type—called LDL (low-density lipoprotein)—can be harmful. It can build up in your arteries and increase your risk of heart disease and stroke.

There’s also HDL (high-density lipoprotein), which is the “good” cholesterol that helps remove LDL from your body.

 

Why High Cholesterol Is Dangerous

  • Clogs arteries and restricts blood flow
     

  • Increases risk of heart attacks and strokes
     

  • Can lead to high blood pressure
     

  • May affect kidney and liver function
     

The scariest part? High cholesterol usually has no symptoms. That’s why it’s called a silent killer and must be managed before problems begin.

 

7 Simple Habits to Avoid High Cholesterol

 

1. Eat Fiber-Rich Foods Daily

Soluble fiber binds with cholesterol in the gut and removes it from your body.

Best foods for fiber:

  • Oats and barley
     

  • Apples, pears, and oranges
     

  • Beans and lentils
     

  • Flaxseeds and chia seeds
     

Tip: Start your morning with a bowl of oatmeal and add a fruit—it’s a heart-healthy breakfast!

 

2. Stay Active Every Day

Physical activity boosts HDL (good cholesterol) and burns fat that raises LDL.

What to do:

  • Walk briskly for 30 minutes a day
     

  • Try yoga, cycling, or dancing
     

  • Use stairs instead of the lift
     

  • Take short walks after meals
     

Even small movements throughout the day matter.

 

3. Cut Down on Saturated & Trans Fats

These fats raise your LDL cholesterol quickly.

Avoid:

  • Fried food, chips, and baked snacks
     

  • Ghee-heavy sweets
     

  • Processed foods with “hydrogenated oils”
     

Choose instead:

  • Olive oil or mustard oil
     

  • Grilled or baked foods
     

  • Fresh fruits and nuts as snacks
     

 

4. Manage Your Stress

Stress affects your hormones and may raise your cholesterol over time.

Try this:

  • Practice deep breathing or meditation
     

  • Do relaxing hobbies like reading or gardening
     

  • Take tech breaks and sleep 7–8 hours daily
     

  • Talk to someone if you’re feeling overwhelmed
     

A calm mind supports a healthy heart.

 

5. Stay Hydrated and Cut Sugary Drinks

Water helps regulate body functions and weight, which both impact cholesterol.

Do this:

  • Drink 8–10 glasses of water daily
     

  • Avoid soft drinks and energy drinks
     

  • Switch to herbal teas or infused water
     

Too much sugar can raise triglyceride levels, a type of fat in your blood.

 

6. Quit Smoking and Limit Alcohol

Smoking lowers good cholesterol and damages arteries. Alcohol, in excess, can also spike cholesterol and blood pressure.

Tip:
Even reducing smoking or drinking frequency helps your heart function better.

 

7. Get Regular Cholesterol Tests

Don’t wait for symptoms. Get your lipid profile checked every year, especially if you have:

  • A family history of heart disease
     

  • Diabetes or high blood pressure
     

  • Obesity or unhealthy lifestyle habits
     

Suggested Test:
Lipid Profile Test by Thyrocare via SecondMedic.com – includes LDL, HDL, total cholesterol, and triglycerides with home sample collection.

 

Normal Cholesterol Levels:

Type

Ideal Range

Total Cholesterol

Below 200 mg/dL

LDL (Bad)

Below 100 mg/dL

HDL (Good)

Above 40 mg/dL (men), 50 mg/dL (women)

Triglycerides

Below 150 mg/dL

 

Tips to Book a Test via SecondMedic:

  1. Visit www.secondmedic.com
     

  2. Search for Lipid Profile Test – Thyrocare
     

  3. Select home collection
     

  4. Fast for 9–12 hours before the test
     

  5. Get results in 24–48 hours
     

 

Bonus Tips

  • Replace white rice with brown rice or millets
     

  • Choose low-fat milk and curd
     

  • Snack on almonds or walnuts
     

  • Cook at home more often than eating out
     

  • Maintain a healthy weight
     

 

Conclusion

You don’t need fancy diets or harsh treatments to manage cholesterol. Just a few simple daily habits can make a big difference in protecting your heart.

By eating better, moving more, managing stress, and staying hydrated, you can keep your cholesterol in check without medication in many cases.

Make your heart health a priority starting today!

Start following these simple habits to avoid high cholesterol and keep your heart happy for years to come.

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