• Published on: Jan 20, 2021
  • 1 minute read
  • By: Dr Rajan Choudhary

MRNA Vaccines – Uses Beyond COVID

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mRNA vaccines – uses beyond COVID

Last year we estimated it would take over a year for a vaccine against COVID to be approved, with vaccinations expected by spring 2021. Incredibly we have managed to meet this prediction, and by the start of January over 42 million doses have been administered in 51 countries. What is even more astounding is that two of the approved vaccines use a completely new vaccination method never used before. mRNA vaccines can be used to easily deliver a variety of different vaccines by changing the mRNA inside the vaccine capsule, and its benefits may not be limited to just infections.

A recent publication in NATURE has demonstrated the use of mRNA vaccines against auto-immune diseases such as multiple sclerosis. MS is an autoimmune condition in which the protective lining of nerves is destroyed by the body’s immune system, significantly slowing down or altering nerve impulse propagation. This leads to symptoms such as fatigue, vision problems, numbness, tingling, aberrant pain, muscle spasms and weakness.

The study looked at introducing antigen-specific tolerance in mice models of MS. This was achieved by activating anti-inflammatory white blood cells. Normally vaccines activate inflammatory white cells to produce a response but altered mRNA with one specific change to its base structure induces and activates anti-inflammatory cells instead.

Furthermore, this anti-inflammatory response is specific to cells that are activated by and attack the body’s nerve cells, thereby delivering a targeted response and not affecting the immune response against infections or cancer. Global immunosuppression is a common side effect of steroids and chemotherapy agents that are normally used to treat auto-immune conditions, and mRNA vaccines may avoid this side effect altogether.

A further advantage is its versatility. This has been demonstrated against multiple sclerosis, but changing the mRNA delivered by the vaccine, it may prove beneficial in far more auto-immune conditions. Of course, we have to emphasize this was an animal study and human trials are unlikely to happen in the next few years, but this study nicely demonstrates how the impact of the COVID pandemic may already be providing beneficial gains for the future.

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Clothing drives

Clothing Drives for Secondhand Donation: Serving Society Sustainably

Clothing is a basic human need, yet millions of people across India lack access to adequate apparel, especially during extreme weather conditions. At the same time, urban households discard large volumes of wearable clothing each year. Clothing drives for secondhand donation bridge this gap by connecting surplus with need in a dignified, sustainable manner.

These initiatives are not merely charitable activities. They represent a structured approach to social responsibility, environmental stewardship and community wellbeing.

 

The Growing Need for Clothing Donation in India

India faces significant socio-economic disparity.

According to government and NGO data:

  • millions live below the poverty line

  • seasonal weather exposes vulnerable populations to health risks

  • access to basic clothing remains inconsistent

Clothing insecurity directly affects dignity, health and social participation.

 

Environmental Impact of Textile Waste

The fashion and textile industry is among the largest contributors to environmental pollution.

Textile waste leads to:

  • landfill accumulation

  • water pollution from dyes

  • increased carbon footprint

Reusing clothing through donation significantly reduces environmental strain.

 

Why Secondhand Clothing Matters

Secondhand clothing extends the lifecycle of garments.

Benefits include:

  • reduced demand for new production

  • conservation of water and energy

  • lower environmental emissions

According to sustainability studies, reuse has a far lower environmental cost than recycling or disposal.

Social Impact of Clothing Drives

Clothing donation drives provide:

  • protection from heat, cold and rain

  • improved hygiene and comfort

  • enhanced dignity and self-esteem

For recipients, clean, appropriate clothing supports physical health and social inclusion.

 

Role of Clothing Drives in Community Wellbeing

Community-based donation drives:

  • encourage collective responsibility

  • foster empathy and awareness

  • strengthen social bonds

When organised locally, they ensure relevance and timely distribution.

 

Corporate and Institutional Participation

Many organisations integrate clothing drives into CSR initiatives.

Benefits for organisations include:

  • measurable social impact

  • employee engagement

  • alignment with sustainability goals

EY-FICCI CSR reports highlight employee-driven social initiatives as highly effective engagement tools.

 

How to Organise an Effective Clothing Drive

Successful drives follow structured processes.

Key steps include:

  • clear communication on donation guidelines

  • segregation by size, gender and season

  • quality checks for usability

  • hygienic packing and storage

Organisation ensures dignity for recipients.

 

Importance of Quality and Dignity

Donations should always respect the recipient.

Essential guidelines:

  • clothes must be clean and wearable

  • damaged or unusable items should be excluded

  • culturally appropriate clothing should be prioritised

Dignified donation builds trust and respect.

 

Seasonal Relevance of Clothing Drives

Seasonal drives maximise impact.

Examples include:

  • winter clothing drives

  • monsoon protection apparel

  • school clothing collections

Timing ensures practical usefulness.

 

Health and Wellbeing Benefits

Adequate clothing reduces:

  • exposure-related illnesses

  • skin infections

  • respiratory conditions during cold weather

WHO recognises appropriate clothing as a basic determinant of health.

Sustainability and Circular Economy

Clothing drives support a circular economy by:

  • keeping materials in use longer

  • reducing waste generation

  • encouraging responsible consumption

They align with global sustainability goals.

Community Partnerships and NGOs

Collaborating with NGOs ensures:

  • efficient distribution

  • identification of genuine needs

  • transparency and accountability

Partnerships amplify reach and impact.

Measuring the Impact of Clothing Drives

Impact can be assessed through:

  • number of beneficiaries

  • quantity of clothing reused

  • environmental waste reduction

  • community feedback

Data-driven evaluation improves future initiatives.

Challenges and How to Address Them

Common challenges include:

  • poor-quality donations

  • storage and logistics issues

  • uneven distribution

Clear guidelines and partnerships help overcome these barriers.

Long-Term Value of Sustainable Donation Drives

Regular clothing drives:

  • normalise responsible disposal habits

  • build sustainable communities

  • encourage conscious consumption

They move society from waste to welfare.

 

Integrating Clothing Drives with Broader Wellness Initiatives

Clothing drives complement:

  • health camps

  • nutrition programs

  • community wellness initiatives

Holistic approaches improve overall social wellbeing.

 

Conclusion

Clothing drives for secondhand donation represent a powerful intersection of compassion and sustainability. By redirecting wearable clothing to those who need it most, these initiatives protect dignity, improve health outcomes and reduce environmental impact. In a society striving for sustainable development, organised clothing donation drives serve as practical, high-impact actions that benefit communities and the planet alike. When individuals and organisations come together to serve responsibly, small acts of reuse create lasting social change.

 

References

  • World Health Organization (WHO) – Social Determinants of Health Reports
  • Indian Council of Medical Research (ICMR) – Environmental and Community Health Studies
  • NITI Aayog – Sustainability and Social Impact Frameworks
  • EY-FICCI – Corporate Social Responsibility and Sustainability Reports
  • Statista – Textile Waste and Sustainability Data
  • UN Environment Programme – Sustainable Consumption and Circular Economy

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