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Published on: Jan 20, 2021
1 minute read
By: Dr Rajan Choudhary

MRNA Vaccines – Uses Beyond COVID

mRNA vaccines – uses beyond COVID

Last year we estimated it would take over a year for a vaccine against COVID to be approved, with vaccinations expected by spring 2021. Incredibly we have managed to meet this prediction, and by the start of January over 42 million doses have been administered in 51 countries. What is even more astounding is that two of the approved vaccines use a completely new vaccination method never used before. mRNA vaccines can be used to easily deliver a variety of different vaccines by changing the mRNA inside the vaccine capsule, and its benefits may not be limited to just infections.

A recent publication in NATURE has demonstrated the use of mRNA vaccines against auto-immune diseases such as multiple sclerosis. MS is an autoimmune condition in which the protective lining of nerves is destroyed by the body’s immune system, significantly slowing down or altering nerve impulse propagation. This leads to symptoms such as fatigue, vision problems, numbness, tingling, aberrant pain, muscle spasms and weakness.

The study looked at introducing antigen-specific tolerance in mice models of MS. This was achieved by activating anti-inflammatory white blood cells. Normally vaccines activate inflammatory white cells to produce a response but altered mRNA with one specific change to its base structure induces and activates anti-inflammatory cells instead.

Furthermore, this anti-inflammatory response is specific to cells that are activated by and attack the body’s nerve cells, thereby delivering a targeted response and not affecting the immune response against infections or cancer. Global immunosuppression is a common side effect of steroids and chemotherapy agents that are normally used to treat auto-immune conditions, and mRNA vaccines may avoid this side effect altogether.

A further advantage is its versatility. This has been demonstrated against multiple sclerosis, but changing the mRNA delivered by the vaccine, it may prove beneficial in far more auto-immune conditions. Of course, we have to emphasize this was an animal study and human trials are unlikely to happen in the next few years, but this study nicely demonstrates how the impact of the COVID pandemic may already be providing beneficial gains for the future.

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Monthly Health Survey via SecondMedic App: A Smarter Approach to Preventive Healthcare

Healthcare is gradually shifting from reactive treatment to proactive prevention. Traditional health models rely heavily on annual checkups or medical visits only after symptoms become severe. However, many chronic and lifestyle-related conditions develop silently over time. The Monthly Health Survey via the SecondMedic App addresses this gap by enabling continuous health monitoring and early risk identification.

According to the Indian Council of Medical Research (ICMR) and NITI Aayog, early detection and preventive care are critical to reducing the growing burden of non-communicable diseases in India. Digital health tools play a key role in achieving this shift.

What Is the Monthly Health Survey?

The Monthly Health Survey is a structured digital questionnaire delivered through the SecondMedic App. It captures key health indicators such as:

recurring symptoms
lifestyle habits
stress and sleep patterns
nutrition and activity levels
chronic condition markers

By repeating the survey monthly, subtle health trends become visible.

Why Monthly Health Tracking Matters

Annual Checkups Miss Gradual Changes

Many health issues develop slowly. Annual tests may appear normal while symptoms quietly progress between visits.

Monthly surveys:

detect early warning signs
capture symptom patterns
identify lifestyle-related risks

Health Is Dynamic, Not Static

Stress, sleep, diet and activity fluctuate monthly. Regular tracking reflects real-life health variation more accurately than isolated tests.

How the Monthly Health Survey Works

Each month, users answer a guided set of questions related to:

physical symptoms
mental wellbeing
lifestyle behaviours
known medical conditions

The app analyses responses to highlight:

risk trends
symptom persistence
areas needing attention

This structured approach simplifies health awareness.

Key Health Areas Covered

Symptom Monitoring

Persistent fatigue, headaches, breathlessness or digestive issues are tracked across months to identify patterns.

Lifestyle Risk Factors

The survey captures:

sedentary behaviour
sleep quality
stress levels
dietary habits

These factors strongly influence long-term health outcomes.

Chronic Disease Indicators

For individuals with diabetes, hypertension or thyroid conditions, monthly monitoring supports better disease control and early escalation.

Role in Preventive Healthcare

Preventive healthcare focuses on stopping disease before complications arise.

Monthly health surveys support prevention by:

identifying risks early
prompting timely consultations
supporting lifestyle modification
reducing emergency care needs

WHO and NITI Aayog both highlight digital monitoring as a cornerstone of preventive health systems.

Benefits for Individuals

Early Awareness

Users become aware of health changes before symptoms become severe.

Empowered Decision-Making

Access to regular health insights encourages proactive lifestyle choices.

Reduced Anxiety

Structured tracking reduces uncertainty and fear about unexplained symptoms.

Better Doctor Consultations

Survey data provides doctors with a clearer health history, improving consultation quality.

Benefits for Chronic Care Management

For chronic conditions, consistency is key.

Monthly surveys help:

track symptom control
identify early deterioration
support medication adherence
reduce complications

This continuous loop improves long-term outcomes.

Data-Driven Personalised Care

The survey supports personalised care by:

tailoring recommendations
prioritising high-risk users
guiding preventive interventions

This approach moves healthcare from generic advice to individualised guidance.

Privacy and Responsible Use

Health data is sensitive.

The survey framework is designed to:

collect only relevant information
support medical decision-making
maintain confidentiality

Responsible data use builds trust and long-term engagement.

Why Digital Surveys Are Effective in India

India’s healthcare challenges include:

large population
limited access to preventive care
high lifestyle disease burden

Digital surveys overcome barriers by:

being accessible anywhere
requiring minimal time
enabling large-scale preventive monitoring

This scalability makes them highly impactful.

Integration with Broader Health Ecosystems

Monthly health surveys work best when integrated with:

medical consultations
diagnostic services
preventive checkups
digital health records

Integration ensures continuity of care.

Long-Term Impact on Healthcare Outcomes

Over time, regular health tracking leads to:

earlier diagnoses
reduced hospitalisations
better chronic disease control
lower healthcare costs
improved quality of life

Lancet studies show that continuous monitoring significantly improves preventive outcomes.

Who Should Use a Monthly Health Survey?

adults over 30
individuals with chronic conditions
people with high-stress lifestyles
those focusing on preventive health
corporate wellness participants

Proactive monitoring benefits all age groups.

Conclusion

The Monthly Health Survey via the SecondMedic App represents a modern, preventive approach to healthcare. By capturing health trends regularly rather than annually, it empowers individuals to act early, supports doctors with better insights and reduces the burden of advanced disease. In an era where prevention is the most effective medicine, monthly health surveys transform awareness into action and data into healthier lives.

References

Indian Council of Medical Research (ICMR) – Preventive Healthcare and Early Detection Report
NITI Aayog – Digital Health and Preventive Care Strateg
World Health Organization (WHO) – Digital Health Monitoring Guideline
Lancet – Preventive Healthcare and Continuous Monitoring Studies
National Health Authority – Digital Health Mission Indi
Statista – Digital Health App Adoption Trends India

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