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Published on: Jul 17, 2020
2 minute read
By: Dr Rajan Choudhary

MRNA Vaccine Against SARS CoV2

An mRNA Vaccine against SARS CoV2

We have previously discussed vaccines against SARS-CoV-2, the virus responsible for COVID-19. On the 14th of July, a preliminary study was published in the New England Journal of Medicine, an internationally reputable medical journal. This study looks at mRNA vaccines in Phase 1 human clinical trials, a first for the virus. Here we will discuss what this means and the results of the study.

mRNA vaccine

Vaccines target the immune system’s memory by presenting them with pieces of these infective diseases. The small amounts do not cause any infective symptoms, but if the person is infected later in life their body will mount a quicker response and prevent them from falling ill. These vaccines can contain broken up parts of the organisms, “dead” organisms or “live” versions that have been severely weakened so they cannot cause any harm.

In 2018 a new type of vaccine was described. Instead of using pre-made protein markers that identify infectious organisms, mRNA vaccines contain genetic material with instructions to produce these markers. Once injected, the person’s cells use these instructions to produce copies of these protein markers. These markers are displayed on the surface of the cell, which in turn is recognized by the immune system, initiating an immune response and producing protective antibodies.

BENEFITS

A major advantage of RNA vaccines is the ease by which they can be made in a laboratory from a DNA template. During a pandemic, this would result in a rapid response and vaccine against a new disease. Conventional vaccines require the use of chicken eggs or cells to produce the vaccines, which can be expensive and time-consuming. These vaccines can be delivered via injections into the skin, blood, muscle, or organs, needle-free into the skin, or via nasal spray. Because these vaccines are so new, we still do not know the best way to deliver it.

Because these vaccines are not made with parts of infective organisms or from live organisms, they are not infectious and will not cause harm through a strong immune response to the vaccine itself, or by causing the disease they aim to vaccinate against. They also appear to be very efficient at generating a reliable immune response to produce antibodies and are well tolerated with few side effects.

NEEDS IMPROVEMENT

Because these types of vaccines are so new there is still a lot we do not understand about them. They may cause unintended effects that we have not yet encountered in human clinical studies. These vaccines also need to be frozen or refrigerated, and so would not be suitable for countries with limited or no refrigeration facilities.

COVID

The SARS-CoV-2 mRNA vaccine codes for one of the virus’ surface spike proteins, responsible for recognizing target cells and fusing the virus into the cell for entry and infection. It was previously recognized as a target for the SARS and MERS viruses.

45 participants received 2 intramuscular injections 28 days apart. None of the participants had any serious side effects after the first injection, or any side effects significant enough to stop the trial. Many had minor to moderate side effects after their second injection (such as fatigue, chills, headache, myalgia, and pain at the injection site), and half the participants taking high dose vaccines had febrile side effects. Overall the side effects were rated as acceptable.

Prior to the vaccine trials, none of the participants had any antibodies against COVID, or any capacity to stop a COIVD infection. After the injections, all participants had noticeable increases in antibodies produced, measurable in their blood. After 43 days, the participant's blood had enough antibodies to reduce infection by SARS-CoV-2 by over 80%.

What is the takeaway? The vaccine is capable of producing an adequate response to protect the vaccine recipient without eliciting any major side effects. These results will be used in phase 2 clinical trials (enrolment began in May) and a phase 3 trial in July 2020. Essentially this means further human trials to further look for side effects in a larger number of volunteers with a more diverse health profile.

This represents an interesting development in producing a rapid vaccine against a new virus responsible for a world-changing pandemic. This new type of vaccine may be the future of vaccines for a broader range of viruses, bacteria, and even cancers.

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Masseuse Visits: How Monthly Stress Relief Camps Improve Workplace Well-Being

Stress has become one of the most common health challenges of modern life. Long working hours, screen exposure, sedentary routines and emotional pressures create a constant state of physical and mental tension. Over time, this stress accumulates and begins to affect sleep, productivity, immunity and emotional stability. This is why masseuse visits through monthly stress relief camps are emerging as a valuable wellness intervention.

These camps are not about luxury or indulgence. They are structured, preventive wellness initiatives designed to help people relax, reset and restore balance in their bodies and minds.

Why Stress Needs Structured Management

Stress is not always visible, but its impact is real.

Chronic stress contributes to:

muscle tension and body pain
headaches and migraines
anxiety and irritability
sleep disturbances
weakened immunity

According to WHO, unmanaged stress is a significant risk factor for both physical and mental health disorders.

What Are Monthly Stress Relief Camps?

Monthly stress relief camps are organised wellness sessions that focus on relaxation-based therapies. Massage visits form a central component of these camps, where trained therapists provide structured massage sessions aimed at relieving physical tension and calming the nervous system.

These camps typically include:

short therapeutic massage sessions
guided relaxation techniques
posture awareness
breathing exercises

They are designed to be accessible, time-efficient and safe.

How Massage Therapy Reduces Stress

Massage works through multiple biological pathways.

Nervous System Regulation

Massage activates the parasympathetic nervous system, which is responsible for rest and recovery. This helps:

lower heart rate
reduce blood pressure
calm the mind

Reduction of Stress Hormones

Studies show massage lowers cortisol levels, the primary stress hormone.

Lower cortisol is linked to:

improved mood
better sleep
enhanced immune response

Muscle Relaxation

Long hours of sitting or standing cause muscle stiffness.

Massage helps by:

improving blood flow
releasing muscle knots
reducing stiffness

This improves physical comfort.

Mental Health Benefits of Masseuse Visits

Mental health is closely tied to physical relaxation.

Regular massage sessions:

reduce anxiety
promote calmness
improve emotional stability
enhance overall mood

Lancet research highlights the role of physical relaxation techniques in supporting mental health outcomes.

Why Monthly Frequency Matters

One-time relaxation is not enough.

Monthly camps:

provide consistent relief
prevent stress buildup
encourage routine self-care

Consistency is the foundation of preventive wellness.

Who Benefits from Stress Relief Camps?

These camps benefit:

working professionals
caregivers
students
frontline workers
individuals with sedentary lifestyles

Anyone experiencing chronic stress can benefit.

Workplace Impact of Stress

Workplace stress affects both individuals and organisations.

It leads to:

reduced productivity
burnout
absenteeism
poor job satisfaction

NITI Aayog reports emphasize the need for preventive wellness initiatives at workplaces.

How Masseuse Visits Improve Workplace Wellness

Enhanced Focus and Productivity

Relaxed muscles and a calm mind improve concentration.

Reduced Musculoskeletal Pain

Massage addresses:

neck pain
shoulder tension
lower back discomfort

Common in desk-based roles.

Better Sleep Quality

Stress relief improves sleep, which further enhances mental clarity.

Positive Workplace Culture

Wellness initiatives show employees that their health matters.

Physical Health Benefits Beyond Relaxation

Massage therapy improves:

circulation
lymphatic drainage
joint mobility
posture awareness

These benefits reduce long-term health risks.

Safety and Professional Standards

Masseuse visits in stress relief camps should:

use trained professionals
follow hygiene protocols
offer non-invasive techniques
respect personal boundaries

Safety and dignity are essential.

Integration with Preventive Healthcare

Stress relief camps complement:

health screenings
mental health counseling
nutrition programs
fitness initiatives

They form part of a holistic wellness ecosystem.

How Monthly Camps Encourage Self-Care

Many people ignore early stress signals.

Regular wellness camps:

normalize self-care
promote early intervention
reduce stigma around mental health

This proactive approach prevents burnout.

Measuring the Impact of Stress Relief Camps

Impact can be assessed through:

stress level surveys
absenteeism rates
employee feedback
productivity metrics

Data helps refine future programs.

Long-Term Value of Stress Relief Programs

Over time, organisations notice:

improved morale
reduced healthcare costs
higher engagement
stronger loyalty

Preventive care always costs less than treatment.

Common Myths About Massage-Based Wellness

Myth: Massage is only for luxury

Reality: It is a validated stress management technique.

Myth: It is temporary relief

Reality: Regular sessions offer cumulative benefits.

Myth: Only physical benefits exist

Reality: Mental and emotional benefits are equally important.

Why Holistic Stress Management Matters

Stress affects:

hormones
digestion
immunity
sleep
emotional regulation

Addressing it holistically leads to lasting improvement.

Conclusion

Masseuse visits through monthly stress relief camps offer far more than temporary relaxation. They represent a structured, preventive approach to managing stress, enhancing mental well-being and supporting physical health. In a world where burnout is becoming increasingly common, consistent wellness interventions help individuals reset, recharge and regain balance. By investing in regular stress relief programs, communities and organisations build healthier, happier and more resilient individuals.

References

World Health Organization (WHO) – Stress and Mental Health Reports
Indian Council of Medical Research (ICMR) – Lifestyle and Stress Research
NITI Aayog – Workplace Wellness and Preventive Healthcare Reports
Lancet – Stress, Burnout and Mental Health Studies
Statista – Global Workplace Wellness Trends
EY-FICCI – Corporate Wellness and Productivity Reports

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