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Published on: Jul 09, 2020
2 minute read
By: Dr Rakesh Choudhary

COVID- 19 Tests – What Do You Need To Know?

COVID- 19 tests – What do you need to know?

Author: Dr. Rakesh Choudhary MBBS, MS, FRCS UK, FRCS Orth UK, MChOrth UK.

Dr. Choudhary is a practicing consultant surgeon in the UK.

So many of us think it is not their job to learn about COVID-19 tests and this should be left for the experts and governments to decide about these tests. But I strongly suggest the public must have a basic understanding of these tests which they may have to have themselves.

Basically there are two types of tests, one which can detect the virus in the body and the other one which tells if the person had the previous infection.

Virus test

The virus test detects an active infection. It detects the genetic material (RNA) of the virus during an active infection. It is also called a PCR (polymerase chain reaction) test or nucleic acid test and is sometimes inaccurately called an antigen test.

A swab is taken from deep in the back of your throat and deep in the nose. The swab should go deep up to 7-8 cm and is generally uncomfortable for the patient. Swabbing patients using the correct technique is paramount in ensuring an accurate result. By simply swabbing the inside of the nasal passage is not deep enough to verify that the virus is present.

What does virus testing tell you?

This test tells us if a patient is actively infected with the COVID-19 virus. Virus testing is used mainly for the diagnosis of COVID-19.

When should it be done?

The virus test works best during the first seven days of symptoms.

The coronavirus can be detected in swabs even before symptoms of illness first appear . This is why people can be infectious for a few days before the onset of symptoms, which usually appear about 5 days after the virus infects. Some people have no symptoms throughout their infection but are positive on the virus test and infectious to others. After a few days of illness, the concentration of the virus falls (as seen in swab samples) and the symptoms of the illness usually recede.

Accuracy of the test

In a person with COVID-19, the test is less likely to give a positive result late in the course of infection once the virus has been cleared by the immune system, or if an inadequate sample is taken from the nose or throat. There are concerns that the rate of ‘false negative’ test results could be as high as 30% and a significant number of people are wrongly being told they do not have the virus.

Antibody test

Antibody tests check your blood by looking for antibodies, which may tell you if you had a past infection with the virus that causes COVID-19. Antibodies are protein structures that are produced by the immune system in response to certain infections. The antibody can help fight off infections and can provide protection against getting that disease again (immunity). Antibodies are disease-specific. For example, measles antibodies will protect you from getting measles if you are exposed to it.

The antibody test detects the presence of antibodies as a marker of past infection. The antibody test (blood test) will only detect infections after the immune system has produced antibodies that recognize the virus. This happens approximately 7–10 days after symptoms develop.

Tests carried out a week after a patient develops symptoms will detect only 30% of people who had COVID-19 infection. Accuracy increases to 72% at two weeks and to 94% in the third week. Some people may take even longer to develop antibodies, and some people who are infected may not ever develop antibodies.

Interpretation of the antibody test is complex for non-medical people. Basically having antibodies to the virus that causes COVID-19 may provide protection from getting infected with the virus again. If it does, we do not know how much protection the antibodies may provide or how long this protection may last.

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Symptoms of Chronic Inflammation in the Body: Early Warning Signs Explained

Inflammation is a natural defense mechanism that helps the body fight infections and heal injuries. However, when inflammation persists for months or even years without a clear cause, it becomes chronic. Chronic inflammation can silently damage tissues and increase the risk of serious diseases.

In India, rising cases of lifestyle diseases such as diabetes, heart disease and autoimmune disorders are often linked to long-term inflammatory processes. Recognizing the symptoms of chronic inflammation in the body is essential for early prevention and treatment.

What Is Chronic Inflammation?

Acute inflammation is short-term and occurs in response to injury or infection. Chronic inflammation, on the other hand, is:

Persistent
Low-grade
Often symptomatically subtle
Linked to long-term health conditions

It may occur due to unhealthy lifestyle habits, stress, obesity or underlying disease.

Common Symptoms of Chronic Inflammation

1. Persistent Fatigue

Ongoing tiredness that does not improve with rest may indicate systemic inflammation.

Inflammatory chemicals in the body can interfere with energy production.

2. Joint and Muscle Pain

Unexplained pain, stiffness or swelling in joints may suggest inflammatory conditions such as arthritis.

Pain may:

Last for weeks
Worsen in the morning
Occur without injury

3. Digestive Issues

Chronic inflammation may affect the gut, leading to:

Bloating
Diarrhea or constipation
Abdominal discomfort
Food sensitivities

Gut health and immune function are closely connected.

4. Frequent Infections

A weakened immune response due to chronic inflammation may result in:

Recurrent colds
Slow wound healing
Persistent sore throat

5. Skin Problems

Inflammatory skin conditions include:

Acne
Eczema
Psoriasis
Rashes

Persistent skin issues may reflect internal inflammation.

6. Brain Fog and Mood Changes

Inflammation can affect brain function, causing:

Difficulty concentrating
Memory issues
Irritability
Low mood

Mental and physical health are interconnected.

7. Unexplained Weight Changes

Inflammation may disrupt metabolism, leading to:

Abdominal weight gain
Difficulty losing weight

Obesity itself can further promote inflammation.

Causes of Chronic Inflammation

Common contributing factors include:

Poor diet high in processed foods
Excess sugar intake
Smoking
Alcohol abuse
Chronic stress
Lack of exercise
Sleep deprivation
Environmental pollution

Addressing these factors is essential for prevention.

Diseases Linked to Chronic Inflammation

Long-term inflammation is associated with:

Type 2 diabetes
Cardiovascular disease
Cancer
Autoimmune disorders
Fatty liver disease
Alzheimer’s disease

Early intervention reduces risk significantly.

How to Reduce Chronic Inflammation Naturally

1. Adopt an Anti-Inflammatory Diet

Include:

Fresh fruits and vegetables
Whole grains
Nuts and seeds
Fatty fish
Olive oil

Avoid processed foods and excessive sugar.

2. Exercise Regularly

Moderate physical activity lowers inflammatory markers.

Aim for at least 30 minutes daily.

3. Manage Stress

Chronic stress increases inflammatory hormones.

Practice:

Meditation
Yoga
Deep breathing exercises

4. Improve Sleep

7–8 hours of quality sleep supports immune regulation.

5. Maintain Healthy Weight

Reducing excess body fat lowers inflammation levels.

6. Avoid Smoking and Limit Alcohol

Both habits promote inflammatory responses in the body.

When to Seek Medical Advice

Consult a healthcare professional if you experience:

Persistent fatigue
Joint swelling
Recurrent infections
Unexplained pain
Long-lasting digestive problems

Blood tests such as C-reactive protein (CRP) may help assess inflammation levels.

Chronic Inflammation in the Indian Context

Rapid urbanization, sedentary lifestyle and dietary shifts in India have contributed to increasing inflammatory-related diseases. Public awareness about preventive measures can significantly reduce healthcare burden.

Early lifestyle changes play a crucial role in improving long-term outcomes.

Conclusion

Chronic inflammation may present subtle symptoms such as fatigue, joint pain, digestive issues and brain fog. Although often overlooked, long-term inflammation can increase the risk of serious diseases.

Adopting healthy eating habits, regular exercise, stress management and adequate sleep can help reduce inflammation naturally. Recognizing early warning signs and seeking medical advice when needed ensures better long-term health.

Taking proactive steps today can prevent major complications tomorrow.

References

Indian Council of Medical Research – Chronic Disease Reports
World Health Organization – Non-Communicable Disease Guidelines
National Institute of Nutrition India – Dietary Recommendations
Lancet Global Health – Inflammation Research
Journal of Clinical Medicine – Chronic Inflammation Studies

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