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Published on: Nov 13, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

What Are Some Common Side Effects Of The COVID-19 Vaccine?

COVID Vaccine, the Pfizer update

On Monday Pfizer announced to the world the vaccine, once it has been developing with Germany's BioNTech, was found to be more than 90?fective. If this is substantiated, it may be possible for countries to receive the vaccine before the end of the year.

The Vaccine is an mRNA Vaccine, a novel method that introduces viral RNA into the body via a viral coat. The vaccine is incorporated into the person's cell, where the viral RNA is read and viral proteins are produced, including the coronavirus coat proteins. As the body reads and recognizes these proteins, it produces antibodies against these viral proteins and activates immune T cells against the virus.

The Pfizer results are based of a phase 3 clinical trial with 43, 538 participants with a diverse background. In this trial, the participants were split between those receiving a vaccine, and those who received a placebo with no effect. The vaccine is administered in two parts, with a 90?ficacy obtained 7 days after the second dose. This would mean a person is vaccinated just 28 days after the initial vaccination.

The FDA usually looks for a minimum 50?ficacy in vaccination when approving new vaccines. It may surprise you that the annual flu jab is also estimated to be 50?fective. The data from Pfizer was verified by an external, independent Data Monitoring Committee. It used data from 94 patients enrolled in the trial and subsequently developed COVID. It is from this groupset that 90% of efficacy is obtained. This is not the final data analysis, and further publications are expected in late November, with a potential FDA Emergency Use Authorisation approval if the data continues to show promise.

If approved, Pfizer has the ability to make 50 million shots before the end of the year, and 1.3 billion by the end of 2021. Many countries are clamoring for their fair share of these limited resources; the US has already negotiated 200m shots, UK 50m, and Germany (one of the major financers for the Pfizer vaccine) over 300m for European Countries.

We should emphasize that rapid vaccine development on this scale at this speed was unheard of prior to COVID. Usually, the animal studies for vaccines can take 1-2 years. In that time Pfizer and others have managed phase 1-3 clinical trials in humans, something that usually takes upwards of 10 years.

There are many unanswered questions that remain from this information.

How safe is the vaccine? Whilst safety information was not published, overall the vaccine appears to have minimal side effects. This is particularly difficult to state however since mRNA vaccines have never been used in people before.
Does the vaccine prevent transmission? In theory, yes. If you are immunized the replication of the virus should be limited significantly, so the number of viruses in each cough will be much lower. However, we do not have data to prove that there is no transmission, but that is also because we have very little data overall.
How long does the protection last? This is a very critical question. The 90?fectiveness rate was calculated just 7 days after the second shot, but it is likely this will change as data is collected over the long term. Some studies have suggested the antibody response fades within months following COVID infection. T Cell immunity on the other hand can stay for years, and it may be the effectiveness of creating a T cell immunity that dictates just how good this vaccine will be .

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Importance of Regular Health Checkups: Early Detection Saves Lives

In today’s fast-paced lifestyle, many individuals prioritise work and family responsibilities while neglecting their own health. However, understanding the importance of regular health checkups is critical for preventing serious medical conditions. Many diseases develop silently without noticeable symptoms, making routine screening essential for early diagnosis and effective treatment.

According to the Indian Council of Medical Research (ICMR), non-communicable diseases such as diabetes, hypertension and cardiovascular conditions are rising across India. Early detection through preventive checkups significantly reduces complications and mortality.

What Are Regular Health Checkups?

Regular health checkups involve:

routine blood tests
blood pressure monitoring
cholesterol screening
organ function tests
lifestyle risk assessments

These assessments help identify abnormalities before they progress into severe conditions.

Why Preventive Healthcare Matters

Preventive healthcare focuses on:

identifying risk factors
detecting disease early
preventing complications

The World Health Organization states that preventive care reduces long-term healthcare burden and improves life expectancy.

Early Detection of Chronic Diseases

Diabetes

India has over 100 million people living with diabetes, according to ICMR data. Many individuals are unaware until complications arise.

Early screening detects:

elevated blood sugar
insulin resistance

Hypertension

NFHS-5 reports that nearly one in four adults in India has hypertension.

Regular monitoring prevents:

stroke
heart attack
kidney damage

Heart Disease

Cholesterol screening identifies risk before symptoms appear.

Timely lifestyle modifications reduce cardiovascular events.

Cancer Screening and Survival Rates

Screenings such as:

mammograms
Pap smears
colon cancer screening

significantly improve survival when disease is detected early.

Monitoring Organ Function

Regular checkups assess:

liver health
kidney function
thyroid levels

Silent organ dysfunction can be detected early.

Benefits of Regular Health Checkups

Reduced Healthcare Costs

Treating advanced disease is more expensive than preventive care.

Improved Quality of Life

Early treatment reduces long-term complications.

Peace of Mind

Knowing health parameters are normal reduces anxiety.

Better Lifestyle Decisions

Screening results motivate healthier habits.

Who Should Get Regular Health Checkups?

adults above 30 years
individuals with family history of chronic disease
smokers
overweight individuals
sedentary professionals

High-risk groups may require more frequent testing.

Frequency of Health Screenings

General recommendation:

Annual checkup for adults
Biannual or quarterly monitoring for high-risk individuals

Doctors personalise schedules based on medical history.

Corporate Health Checkups

Many organisations conduct:

workplace screening camps
employee wellness programs

These initiatives improve workforce productivity and reduce absenteeism.

Preventive Health in India

NITI Aayog highlights preventive healthcare as essential for reducing national disease burden.

Increasing awareness about routine checkups is critical.

Common Tests in Annual Health Packages

Complete blood count
Lipid profile
Fasting blood sugar
HbA1c
Liver function test
Kidney function test
Thyroid profile
Vitamin levels

These tests provide comprehensive health insight.

Addressing Common Misconceptions

Many people avoid checkups because:

they feel healthy
they fear results
they lack time

However, absence of symptoms does not mean absence of disease.

Lifestyle Diseases and Urbanisation

Urban lifestyles contribute to:

sedentary behaviour
poor diet
stress

Regular monitoring counters these risks.

Digital Health and Screening Accessibility

Online booking platforms and home sample collection make preventive care more accessible and convenient.

Technology supports proactive health management.

Building a Culture of Preventive Health

Encouraging:

annual screenings
family health awareness
workplace initiatives

creates healthier communities.

Conclusion

Understanding the importance of regular health checkups is essential for preventing chronic disease and improving life expectancy. Early detection of diabetes, hypertension, heart disease and other conditions allows timely treatment and reduces complications. Preventive healthcare is not an expense but an investment in long-term wellbeing. Scheduling routine screenings today can protect health and save lives tomorrow.

References

Indian Council of Medical Research (ICMR) – Non-Communicable Disease Reports
National Family Health Survey (NFHS-5) – Adult Health Data
World Health Organization (WHO) – Preventive Healthcare Guidelines
NITI Aayog – National Health and Preventive Strategy Reports
Lancet – Early Detection and Disease Prevention Studies

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