• Published on: Nov 13, 2020
  • 2 minute read
  • By: Dr Rajan ( Medical Second Opinion Cell)

What Are Some Common Side Effects Of The COVID-19 Vaccine?

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COVID Vaccine, the Pfizer update

On Monday Pfizer announced to the world the vaccine, once it has been developing with Germany's BioNTech, was found to be more than 90?fective. If this is substantiated, it may be possible for countries to receive the vaccine before the end of the year.

The Vaccine is an mRNA Vaccine, a novel method that introduces viral RNA into the body via a viral coat. The vaccine is incorporated into the person's cell, where the viral RNA is read and viral proteins are produced, including the coronavirus coat proteins. As the body reads and recognizes these proteins, it produces antibodies against these viral proteins and activates immune T cells against the virus.

The Pfizer results are based of a phase 3 clinical trial with 43, 538 participants with a diverse background. In this trial, the participants were split between those receiving a vaccine, and those who received a placebo with no effect. The vaccine is administered in two parts, with a 90?ficacy obtained 7 days after the second dose. This would mean a person is vaccinated just 28 days after the initial vaccination.

The FDA usually looks for a minimum 50?ficacy in vaccination when approving new vaccines. It may surprise you that the annual flu jab is also estimated to be 50?fective. The data from Pfizer was verified by an external, independent Data Monitoring Committee. It used data from 94 patients enrolled in the trial and subsequently developed COVID. It is from this groupset that 90% of efficacy is obtained. This is not the final data analysis, and further publications are expected in late November, with a potential FDA Emergency Use Authorisation approval if the data continues to show promise.

If approved, Pfizer has the ability to make 50 million shots before the end of the year, and 1.3 billion by the end of 2021. Many countries are clamoring for their fair share of these limited resources; the US has already negotiated 200m shots, UK 50m, and Germany (one of the major financers for the Pfizer vaccine) over 300m for European Countries.

We should emphasize that rapid vaccine development on this scale at this speed was unheard of prior to COVID. Usually, the animal studies for vaccines can take 1-2 years. In that time Pfizer and others have managed phase 1-3 clinical trials in humans, something that usually takes upwards of 10 years.

There are many unanswered questions that remain from this information.

  1. How safe is the vaccine? Whilst safety information was not published, overall the vaccine appears to have minimal side effects. This is particularly difficult to state however since mRNA vaccines have never been used in people before.
  2. Does the vaccine prevent transmission? In theory, yes. If you are immunized the replication of the virus should be limited significantly, so the number of viruses in each cough will be much lower. However, we do not have data to prove that there is no transmission, but that is also because we have very little data overall.
  3. How long does the protection last? This is a very critical question. The 90?fectiveness rate was calculated just 7 days after the second shot, but it is likely this will change as data is collected over the long term. Some studies have suggested the antibody response fades within months following COVID infection. T Cell immunity on the other hand can stay for years, and it may be the effectiveness of creating a T cell immunity that dictates just how good this vaccine will be .
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Why Recurring Sore Throat Can Be a Serious Issue

Why Recurring Sore Throat Can Be a Serious Issue

A sore throat is a common complaint. Most of us experience it during seasonal changes, after a cold, or when we catch the flu. But what if your sore throat keeps coming back again and again? While many people dismiss it as a minor irritation, a recurring sore throat can actually signal more serious health issues that require proper attention.

What is a recurring sore throat?

A recurring sore throat refers to repeated or persistent throat discomfort that comes back multiple times in a year or lasts longer than usual. Normally, a viral sore throat improves within a week. If the problem lingers beyond 10 days or returns frequently, it falls into the category of chronic or recurring sore throat.

Why is it serious?

  1. Undiagnosed infections
    A single sore throat from a virus is not concerning. But if bacterial infections like strep throat keep coming back, they may damage the throat and spread to other parts of the body if untreated.
     

  2. Inflammation and tissue damage
    Constant irritation from allergies or acid reflux can harm the delicate tissues of the throat. Over time, this may affect your voice and overall throat function.
     

  3. Underlying medical conditions
    Recurring sore throat can be linked to issues like gastroesophageal reflux disease (GERD), allergies, tonsil problems, or immune system weakness. In some cases, it may also be an early warning sign of more serious diseases such as tumors.
     

  4. Complications
    Recurrent infections can lead to abscesses around the tonsils, ear infections, or sinus problems. Inadequate or repeated antibiotic use can also cause resistance.
     

  5. Impact on daily life
    A constant sore throat affects your eating, speaking, sleeping, and quality of life. It leads to repeated doctor visits, discomfort, and stress.
     

Common causes of recurring sore throat

  • Bacterial infections like strep throat or chronic tonsillitis
     

  • Viral infections that linger or reactivate
     

  • Allergies that trigger postnasal drip and throat irritation
     

  • Acid reflux or GERD causing stomach acid to irritate the throat
     

  • Environmental irritants such as smoke, dust, and pollution
     

  • Mouth breathing during sleep due to nasal blockage
     

  • Immune weakness making you prone to repeated infections
     

Warning signs to watch for

You should never ignore these symptoms if they accompany a recurring sore throat:

  • Sore throat lasting longer than 2–3 weeks
     

  • Difficulty swallowing or breathing
     

  • Lump or swelling in the throat or neck
     

  • Persistent hoarseness or voice changes
     

  • Unexplained weight loss
     

  • Blood in saliva or phlegm
     

  • Fever with night sweats
     

These are red flags that need immediate medical evaluation.

How lab tests help

Lab tests play a critical role in finding out why you have a recurring sore throat. Some useful investigations include:

  • Throat swab or culture to identify bacterial infections
     

  • Rapid antigen test for strep for quick diagnosis
     

  • Complete Blood Count (CBC) to detect infection or immune problems
     

  • CRP and ESR to check inflammation
     

  • Allergy tests to identify triggers like dust or pollen
     

  • Thyroid function tests to rule out thyroid-related throat problems
     

  • Reflux evaluation if GERD is suspected
     

  • Immune status tests if infections are unusually frequent
     

Through SecondMedic/Thyrocare, these tests can be arranged easily, giving you faster results and treatment planning.

Treatment and prevention

The treatment of recurring sore throat depends on its cause:

  • Bacterial infections are treated with antibiotics prescribed by a doctor. Completing the full course is essential.
     

  • Viral infections usually require rest, hydration, and symptom management.
     

  • Acid reflux can be controlled with lifestyle changes like avoiding late meals, reducing spicy foods, and medications if required.
     

  • Allergies can be managed by identifying and avoiding triggers, along with prescribed medicines.
     

  • Tonsil problems may require surgical removal if infections are frequent and severe.
     

Preventive steps include:

  • Staying hydrated
     

  • Avoiding smoking and exposure to polluted air
     

  • Maintaining good throat hygiene
     

  • Managing acid reflux through diet and posture
     

  • Strengthening immunity with balanced nutrition and rest
     

When to see a doctor

If you suffer from frequent sore throats or if your symptoms come with any red flags, consult a healthcare professional without delay. Early evaluation prevents complications and ensures better outcomes.

Conclusion

Recurring sore throat is more than just an inconvenience. It is often a signal from your body that something is not right. Identifying the cause early and undergoing the right tests can help you recover faster and avoid long-term damage.

At SecondMedic, you can access lab tests, doctor consultations, and treatment guidance all in one place. Don’t ignore a sore throat that keeps returning — take charge of your health today and book your tests with SecondMedic/Thyrocare for accurate results and expert support.

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