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Published on: Nov 13, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

What Are Some Common Side Effects Of The COVID-19 Vaccine?

COVID Vaccine, the Pfizer update

On Monday Pfizer announced to the world the vaccine, once it has been developing with Germany's BioNTech, was found to be more than 90?fective. If this is substantiated, it may be possible for countries to receive the vaccine before the end of the year.

The Vaccine is an mRNA Vaccine, a novel method that introduces viral RNA into the body via a viral coat. The vaccine is incorporated into the person's cell, where the viral RNA is read and viral proteins are produced, including the coronavirus coat proteins. As the body reads and recognizes these proteins, it produces antibodies against these viral proteins and activates immune T cells against the virus.

The Pfizer results are based of a phase 3 clinical trial with 43, 538 participants with a diverse background. In this trial, the participants were split between those receiving a vaccine, and those who received a placebo with no effect. The vaccine is administered in two parts, with a 90?ficacy obtained 7 days after the second dose. This would mean a person is vaccinated just 28 days after the initial vaccination.

The FDA usually looks for a minimum 50?ficacy in vaccination when approving new vaccines. It may surprise you that the annual flu jab is also estimated to be 50?fective. The data from Pfizer was verified by an external, independent Data Monitoring Committee. It used data from 94 patients enrolled in the trial and subsequently developed COVID. It is from this groupset that 90% of efficacy is obtained. This is not the final data analysis, and further publications are expected in late November, with a potential FDA Emergency Use Authorisation approval if the data continues to show promise.

If approved, Pfizer has the ability to make 50 million shots before the end of the year, and 1.3 billion by the end of 2021. Many countries are clamoring for their fair share of these limited resources; the US has already negotiated 200m shots, UK 50m, and Germany (one of the major financers for the Pfizer vaccine) over 300m for European Countries.

We should emphasize that rapid vaccine development on this scale at this speed was unheard of prior to COVID. Usually, the animal studies for vaccines can take 1-2 years. In that time Pfizer and others have managed phase 1-3 clinical trials in humans, something that usually takes upwards of 10 years.

There are many unanswered questions that remain from this information.

How safe is the vaccine? Whilst safety information was not published, overall the vaccine appears to have minimal side effects. This is particularly difficult to state however since mRNA vaccines have never been used in people before.
Does the vaccine prevent transmission? In theory, yes. If you are immunized the replication of the virus should be limited significantly, so the number of viruses in each cough will be much lower. However, we do not have data to prove that there is no transmission, but that is also because we have very little data overall.
How long does the protection last? This is a very critical question. The 90?fectiveness rate was calculated just 7 days after the second shot, but it is likely this will change as data is collected over the long term. Some studies have suggested the antibody response fades within months following COVID infection. T Cell immunity on the other hand can stay for years, and it may be the effectiveness of creating a T cell immunity that dictates just how good this vaccine will be .

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Genetic Testing Services India: How DNA-Based Insights Are Transforming Preventive Healthcare

Genetic testing services in India have rapidly expanded over the last decade, becoming a vital part of preventive healthcare, early diagnosis, and personalized treatment planning. As medical science advances, understanding one’s DNA has become more accessible, accurate, and meaningful. Genetic testing empowers individuals with information about hereditary risks, potential health challenges, and personalized lifestyle recommendations based on their biological blueprint.

With rising chronic disease rates, cancer cases, and lifestyle-driven health issues, India is now embracing DNA-based healthcare as an essential tool for early detection and long-term prevention. SecondMedic integrates genetic insights into its preventive care ecosystem, helping individuals and families make informed decisions about their health.

The Growing Importance of Genetic Testing in India

India has a diverse population with complex genetic structures, making genetic testing particularly valuable. Many hereditary conditions often go undiagnosed until symptoms appear, which sometimes leads to delayed treatment.

Several factors are driving the growth of genetic testing in India:

Increased awareness of hereditary diseases
Rising cancer and cardiac risk among younger populations
Demand for preventive and precision healthcare
Wider availability of DNA-testing technology
Integration of genomics into clinical practice

As people seek more personalized healthcare, genetic testing has become a powerful tool for understanding risk factors long before they cause illness.

What Genetic Testing Reveals About Your Health

Genetic testing examines specific DNA markers to determine predispositions and inherited risks. The results provide clarity about future risks, potential conditions, and biological tendencies that influence long-term health.

Genetic testing can reveal:

Predisposition to cancer
Heart disease risk
Diabetes and metabolic disorders
Thyroid and hormonal disorders
Lipid metabolism issues
Neurological and genetic syndromes
Response to medicines (pharmacogenomics)
Carrier status for inheritable conditions

This information creates a foundation for preventive action, lifestyle modification, and informed medical decisions.

Types of Genetic Testing Available in India

India’s genetic testing ecosystem offers several categories of tests designed for different health needs.

Common types include:

Hereditary cancer risk testing
Cardiac risk genetic screening
Metabolic and lifestyle-based DNA tests
Carrier screening for inheritable conditions
Pharmacogenomic testing
Newborn screening
Whole exome or genome sequencing

SecondMedic works with leading genetic laboratories to deliver clinically validated tests integrated with actionable health insights.

Genetic Testing and Preventive Medicine

Preventive healthcare becomes far more effective when guided by genetic insights. Instead of waiting for symptoms, individuals can take proactive steps based on their specific risk profile.

Genetic testing supports preventive care by:

Identifying risks early
Recommending personalized diet and exercise plans
Providing medication compatibility insights
Monitoring high-risk individuals more closely
Guiding screening schedules

This approach significantly reduces the likelihood of severe disease progression.

Integration of Genetic Testing with Precision Medicine

Precision medicine aims to deliver treatments tailored to individual biology. Genetic testing is central to this approach, helping doctors customize care.

Genetic insights influence:

Selecting the right medications
Determining accurate dosages
Avoiding harmful drug reactions
Recommending targeted therapies
Planning long-term health strategies

SecondMedic combines genetic data with electronic health records, lab reports, and lifestyle assessments to build comprehensive care plans.

Genetic Testing and Family Health Management

Understanding genetic risks does not only benefit individuals—it supports entire families. Many conditions are passed down through generations and early awareness can help protect family members.

Genetic testing helps families identify:

Hereditary cancer patterns
Recessive or dominant genetic traits
Chromosomal conditions
Diseases likely to appear later in life

SecondMedic provides family-focused genetic counseling that helps relatives assess their own risks based on shared history.

Safety, Accuracy, and Reliability of Genetic Testing

Modern genetic testing is safe, non-invasive, and highly reliable. Most tests require only a saliva sample or a painless cheek swab. Laboratories then analyze DNA using advanced sequencing technologies.

Accuracy is ensured through:

Globally validated testing panels
High-depth DNA sequencing
Cross-verified genetic markers
Clinically certified laboratories
Medical review of results

SecondMedic ensures that genetic reports are interpreted by certified experts for practical application.

The Role of Genetic Counseling in DNA-Based Healthcare

Raw DNA data alone is not enough. Patients need clear guidance on how to understand and apply genetic results. Genetic counseling helps individuals navigate results confidently and make informed decisions.

Counseling includes:

Explanation of risk levels
Genetic pattern interpretation
Clear preventive recommendations
Family planning guidance
Personalized lifestyle strategies

SecondMedic offers genetic counseling alongside reports to ensure meaningful, actionable insights.

How SecondMedic Integrates Genetic Testing into Preventive Care

SecondMedic creates a seamless experience where genetic testing becomes part of a broader health management plan. After receiving results, individuals gain access to personalized nutrition, fitness, screening schedules, and digital monitoring tools.

SecondMedic’s approach includes:

Personalized DNA-based health reports
Doctor-reviewed insights
Custom preventive health plans
Ongoing monitoring and follow-up
Integration with AI-based risk scoring
Virtual consultations with specialists

This ensures long-term support based on accurate genetic understanding.

The Future of Genetic Testing in India

Genomics is set to transform Indian healthcare in the coming years. As technology becomes more affordable and awareness grows, genetic testing will become a routine part of preventive health.

Upcoming trends include:

Widespread use of pharmacogenomics
DNA-based nutrition personalization
Expanded newborn genetic screening
AI-driven genetic interpretation
Integration with national digital health records
Genetic-based early disease prediction

SecondMedic aims to make genetic testing accessible, affordable, and clinically meaningful for individuals across India.

Conclusion

Genetic testing services in India are unlocking powerful insights that empower individuals to take control of their health. Through DNA-based risk assessment, hereditary screening, and precision medicine, genetic testing creates a pathway to informed, preventive, and personalized healthcare. SecondMedic integrates these insights into comprehensive wellness plans, giving users long-term guidance for healthier living.

To book genetic testing or explore DNA-based health programs, visit www.secondmedic.com

References

NITI Aayog – Genomics and Precision Medicine India
ICMR – Genetic Disorders in India 2024
IMARC – Indian Genetic Testing Market Report
WHO – Human Genomics in Healthcare
Nature Genetics – Global Genetic Risk Studies

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