Call / Whatsapp
+918447748545

Published on: Nov 13, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

What Are Some Common Side Effects Of The COVID-19 Vaccine?

COVID Vaccine, the Pfizer update

On Monday Pfizer announced to the world the vaccine, once it has been developing with Germany's BioNTech, was found to be more than 90?fective. If this is substantiated, it may be possible for countries to receive the vaccine before the end of the year.

The Vaccine is an mRNA Vaccine, a novel method that introduces viral RNA into the body via a viral coat. The vaccine is incorporated into the person's cell, where the viral RNA is read and viral proteins are produced, including the coronavirus coat proteins. As the body reads and recognizes these proteins, it produces antibodies against these viral proteins and activates immune T cells against the virus.

The Pfizer results are based of a phase 3 clinical trial with 43, 538 participants with a diverse background. In this trial, the participants were split between those receiving a vaccine, and those who received a placebo with no effect. The vaccine is administered in two parts, with a 90?ficacy obtained 7 days after the second dose. This would mean a person is vaccinated just 28 days after the initial vaccination.

The FDA usually looks for a minimum 50?ficacy in vaccination when approving new vaccines. It may surprise you that the annual flu jab is also estimated to be 50?fective. The data from Pfizer was verified by an external, independent Data Monitoring Committee. It used data from 94 patients enrolled in the trial and subsequently developed COVID. It is from this groupset that 90% of efficacy is obtained. This is not the final data analysis, and further publications are expected in late November, with a potential FDA Emergency Use Authorisation approval if the data continues to show promise.

If approved, Pfizer has the ability to make 50 million shots before the end of the year, and 1.3 billion by the end of 2021. Many countries are clamoring for their fair share of these limited resources; the US has already negotiated 200m shots, UK 50m, and Germany (one of the major financers for the Pfizer vaccine) over 300m for European Countries.

We should emphasize that rapid vaccine development on this scale at this speed was unheard of prior to COVID. Usually, the animal studies for vaccines can take 1-2 years. In that time Pfizer and others have managed phase 1-3 clinical trials in humans, something that usually takes upwards of 10 years.

There are many unanswered questions that remain from this information.

How safe is the vaccine? Whilst safety information was not published, overall the vaccine appears to have minimal side effects. This is particularly difficult to state however since mRNA vaccines have never been used in people before.
Does the vaccine prevent transmission? In theory, yes. If you are immunized the replication of the virus should be limited significantly, so the number of viruses in each cough will be much lower. However, we do not have data to prove that there is no transmission, but that is also because we have very little data overall.
How long does the protection last? This is a very critical question. The 90?fectiveness rate was calculated just 7 days after the second shot, but it is likely this will change as data is collected over the long term. Some studies have suggested the antibody response fades within months following COVID infection. T Cell immunity on the other hand can stay for years, and it may be the effectiveness of creating a T cell immunity that dictates just how good this vaccine will be .

Read Blog

The Rise of Telemedicine: Revolutionizing Healthcare

In today’s fast-paced world, convenience is key. From online shopping to digital banking, everything is just a click away. The healthcare industry is no exception to this digital revolution, with telemedicine emerging as a game-changer. This new wave of healthcare delivery has not only made medical consultations more accessible but also provided timely care to patients, especially in remote areas. In this blog, we will explore the rise of telemedicine, its benefits, challenges, and the role it plays in shaping the future of healthcare.

What is Telemedicine?

Telemedicine refers to the use of digital technology, such as video calls, phone calls, or messaging apps, to provide healthcare services remotely. Through telemedicine platforms, patients can consult with doctors, discuss symptoms, receive medical advice, and even get prescriptions – all without stepping out of their homes. While the concept of remote healthcare isn’t entirely new, it has gained significant traction in recent years due to advancements in technology and the widespread use of smartphones and internet connectivity.

The Growth of Telemedicine

The COVID-19 pandemic served as a major catalyst for the widespread adoption of telemedicine. With lockdowns and social distancing measures in place, many people were unable or reluctant to visit hospitals or clinics. As a result, healthcare providers turned to telemedicine as a safe and effective way to continue offering care to their patients.

However, even before the pandemic, telemedicine was growing. Factors such as a shortage of healthcare professionals, long waiting times, and the rising cost of healthcare made remote consultations an attractive option. According to a report by McKinsey, telehealth usage in the U.S. increased by 38 times from pre-pandemic levels. Globally, the telemedicine market is expected to grow at a compound annual growth rate (CAGR) of 25.8% from 2020 to 2027.

Benefits of Telemedicine

The rise of telemedicine has brought numerous benefits for both patients and healthcare providers:

1. Increased Access to Care

Telemedicine has made healthcare more accessible, especially for those living in rural or remote areas where access to healthcare facilities is limited. With just a smartphone and an internet connection, patients can connect with healthcare professionals from anywhere, breaking down geographical barriers.

2. Convenience and Time-Saving

For many people, visiting a doctor’s office involves time-consuming travel and long waits. Telemedicine eliminates the need for physical travel, allowing patients to schedule consultations at a time that suits them. This is particularly useful for those with busy schedules, elderly patients, or individuals with mobility issues.

3. Cost-Effective Healthcare

Telemedicine can be a more affordable option for both patients and healthcare providers. Remote consultations typically cost less than in-person visits, and patients save on transportation and other associated expenses. For healthcare providers, telemedicine can help reduce overhead costs by minimizing the need for physical office space and staffing.

4. Continuity of Care

Telemedicine helps patients stay connected with their healthcare providers even when face-to-face visits are not possible. This is particularly important for patients with chronic conditions who require regular monitoring and follow-ups. Remote consultations allow doctors to track their progress and adjust treatment plans without the need for frequent clinic visits.

5. Reduced Risk of Infections

During outbreaks of contagious diseases, such as COVID-19, visiting a hospital or clinic can increase the risk of infection. Telemedicine provides a safer alternative by allowing patients to receive care from the comfort of their homes, thus reducing the spread of diseases.

Challenges Facing Telemedicine

While telemedicine offers many benefits, it also comes with its fair share of challenges:

1. Technology Barriers

Not everyone has access to the internet or the necessary devices for telemedicine consultations. In rural or underserved communities, limited internet connectivity can hinder access to remote healthcare services. Additionally, older adults or those who are not tech-savvy may struggle to navigate telemedicine platforms.

2. Lack of Physical Examination

Telemedicine works well for consultations, but it cannot replace the need for physical examinations in certain cases. While doctors can provide advice based on a patient’s symptoms, there are limitations when it comes to diagnosing conditions that require hands-on assessments or lab tests.

3. Privacy and Security Concerns

Telemedicine relies on the transmission of personal health information over digital platforms. This raises concerns about data privacy and security. Patients need to be assured that their sensitive medical information is protected, and healthcare providers must comply with regulations like the Health Insurance Portability and Accountability Act (HIPAA) to safeguard patient data.

4. Reimbursement and Insurance Issues

In some regions, the reimbursement policies for telemedicine services are not well established. Patients may face difficulties in getting their telemedicine consultations covered by insurance, which can deter them from opting for remote healthcare. On the other hand, healthcare providers may also face challenges in billing for telemedicine services.

The Future of Telemedicine

As technology continues to advance, the future of telemedicine looks promising. With the development of artificial intelligence (AI), wearable health devices, and remote monitoring tools, telemedicine will become more sophisticated and capable of providing personalized care to patients. AI-powered chatbots, for example, could assist doctors in diagnosing conditions by analyzing symptoms and medical history.

Additionally, wearable devices like fitness trackers or smartwatches can monitor a patient’s vital signs in real-time and share the data with their healthcare provider. This continuous flow of information allows for more accurate diagnoses and timely interventions, reducing the need for emergency hospital visits.

Telemedicine in Specialized Care

Telemedicine is also expanding its reach into specialized fields of medicine. For example, telepsychiatry allows mental health professionals to provide counseling and therapy to patients remotely, making mental health services more accessible. Similarly, teledermatology enables dermatologists to diagnose and treat skin conditions by reviewing images sent by patients.

Another emerging trend is the use of telemedicine for post-operative care. Patients recovering from surgery can have follow-up consultations with their doctors without the need for an in-person visit, reducing the burden on both the patient and the healthcare system.

Conclusion

The rise of telemedicine is revolutionizing the way healthcare is delivered. By providing increased access to care, improving convenience, and offering cost-effective solutions, telemedicine is making healthcare more patient-centered and accessible. While challenges such as technology barriers and privacy concerns remain, the continued growth and innovation in telemedicine point towards a future where healthcare is more personalized, efficient, and readily available to all.

As we move forward, telemedicine will continue to play a vital role in bridging the gap between patients and healthcare providers, ensuring that quality care is just a click away.