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Published on: Jul 29, 2021
2 minute read
By: Raj Dwivedi

What Tests Are Used To Manage Anemia And What Do They Mean?

The doctors use a number of tests to diagnose anemia. Hb (hemoglobin) is one of the key indicators used in diagnosis. A hemoglobin test is a blood test that measures how much hemoglobin you have in your red blood cells. A hemoglobin test is generally used for detecting:

In addition, a hemoglobin test can also be carried out to assess bone marrow's response to treatment, evaluate possible blood donation and check the levels of red blood cells in the body. There are certain conditions that may interfere with the results of the hemoglobin test. In such cases, it is recommended to get the test done again.

For the hemoglobin test, a sample of your blood is taken and tested in a clinical laboratory [read more about the process here]. The results are expressed as grams of hemoglobin per deciliter (g/dL) or micrograms per liter (mcg/L). Normal range for this test is 12g/dL - 18g/dL (12.1-18.0 g/L) for adults and 9g/dL - 13g/dL (9.0-13.3 g/L) for children. If the test result comes out to be less than 7 gm, it can indicate a serious condition known as severe anemia. In some cases, the doctors may order follow-up tests to assess the current condition of the patient.

Apart from the hemoglobin test, certain other blood tests can be used for detecting low RBCs (RBC count) or abnormal types of RBC (red cell indices) or hemoglobin (Hb). These include complete blood count tests, reticulocyte tests, iron tests, and red blood cell indices.

In some cases, the doctor may opt to do a bone marrow aspiration and exam to check for any abnormalities in the bone marrow cells. In such cases, it of red blood cells is karyotype to rule out chromosomal disorders.

The most common reason for having an inadequate number of red blood cells in the body is an iron deficiency or anemia. Iron plays a significant role in the production of hemoglobin, which is responsible for carrying oxygen from the lungs to the tissues of other parts of the body. Hence, people suffering from iron are known as sickle cell trait. The tests include:

Complete blood count test - The complete blood cell count (CBC) is a routine test that checks the different components of your blood like number of red blood cells, white blood cells and platelets. It also has information about the size and hemoglobin content in each of these cells. A CBC includes tests for the following:

Reticulocyte test - This is a blood test that measures the reticulocytes (immature red blood cells) in the bloodstream. A high level of reticulocytes can indicate increased production of red blood cells by the bone marrow to compensate for anemia, or destruction of very early stage RBCs which are still unable to mature.

Iron tests - Iron is an essential component for RBC production. A test to assess the iron level in your blood is called a serum ferritin test, which measures the amount of iron stored in the body's cells and tissues. Another way to evaluate low iron levels is by carrying out a transferrin saturation test. In this case, the lab technician will extract serum from your blood sample and measure the amount of transferrin protein present in it. Transferrin is a protein that carries iron to the bone marrow where red blood cells are produced. Thus, if there is an insufficient amount of transferrin protein present in the serum, it shows that there is an inadequate level of stored iron.

Hemoglobin tests - A hemoglobin test is generally carried out to detect anemia, especially if the result of CBC tests are inconclusive. During this test, a small sample of blood is collected from your vein and sent to the laboratory for analysis. The test measures the amount of hemoglobin in your red blood cells.

Red cell indices - Red cell indices are tests that measure the size and hemoglobin content of the red blood cells. The values obtained from these tests can be used to detect anemia and other blood disorders.

Karyotype test - It is a lab test used to evaluate chromosomal abnormalities in red blood cells or bone marrow cells

Low blood cell counts also have other causes, such as infections or tumors. In some cases, low blood cells may indicate a more serious condition like bone marrow failure which requires immediate medical intervention to save the patient from death.

Thus, if you are suffering from any of these conditions and symptoms and suspect that you may be anemic, check with your doctor for the necessary tests to confirm or rule out your suspicions. Early detection and treatment of anemia can save you from serious complications like heart attacks, strokes, blood clots, etc.

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How Overthinking Affects Your Immune System

We all overthink at times—whether it’s replaying past mistakes or worrying about the future. But when overthinking becomes a habit, it doesn’t just affect your peace of mind. Research shows that excessive worrying and stress can directly harm your body’s defense system. Your immune system, which protects you from infections, becomes weaker when your brain is stuck in a constant loop of thoughts.

In this blog, we’ll explore the science behind how overthinking affects your immune system, the symptoms you might notice, and practical ways to protect both your mind and body.

The Science: Why Overthinking Impacts Immunity

Overthinking often triggers chronic stress. When you worry, your body produces stress hormones like cortisol and adrenaline. These hormones are helpful in short bursts, but when they stay elevated for a long time, they can suppress your immune system.

Cortisol suppresses immune cell activity, making it harder for your body to fight off bacteria and viruses.
Stress reduces the production of lymphocytes, the white blood cells that fight infections.
Overthinking keeps your body in “fight-or-flight mode,” which drains energy from essential healing processes.

As a result, people who overthink often notice that they fall sick more easily, recover slower, and feel tired even after rest.

Early Signs That Overthinking Is Affecting Your Health

If you’ve been stuck in a cycle of overthinking, watch out for these warning signs:

Frequent colds or flu – A weak immune system means your body struggles to defend itself.
Slower wound healing – Cuts, bruises, or even post-surgery recovery may take longer.
Constant fatigue – Even after proper sleep, your body feels drained.
Digestive issues – Stress can upset your gut health, which is linked to immunity.
Skin breakouts or rashes – A stressed immune system can worsen inflammation.

These symptoms may look minor at first but can become more serious if ignored.

How Overthinking Increases Risk of Chronic Illness

Prolonged stress doesn’t just weaken immunity temporarily—it can also contribute to long-term health conditions:

Autoimmune diseases: Overactive stress responses may confuse the immune system, making it attack healthy cells.
Chronic inflammation: A stressed mind can keep the body in a state of constant inflammation, increasing risks of arthritis, diabetes, or heart disease.
Mental health decline: Anxiety and depression often go hand-in-hand with overthinking, which worsens immunity further.

This shows why mental health and physical health are deeply connected.

Practical Ways to Break the Cycle and Protect Immunity

The good news is that you can rebuild your immunity by calming your mind. Here are some proven strategies:

1. Practice Mindfulness

Meditation, deep breathing, or simply focusing on the present moment reduces stress hormones and boosts immunity. Even 10 minutes a day can make a difference.

2. Maintain Healthy Sleep

Overthinking often keeps you awake at night, which further weakens immunity. Aim for 7–8 hours of quality sleep, and create a screen-free bedtime routine.

3. Exercise Regularly

Physical activity reduces stress, improves circulation, and enhances immune responses. Even a 30-minute walk daily helps regulate mood and immunity.

4. Eat Immune-Boosting Foods

A balanced diet with fruits, vegetables, whole grains, and protein supports your immune system. Foods rich in Vitamin C, Vitamin D, and Zinc are especially helpful.

5. Journaling and Thought Control

Writing down your thoughts before bedtime can prevent overthinking from spiraling. Challenge negative thoughts with positive affirmations.

6. Limit Caffeine and Alcohol

Both can increase anxiety and disturb sleep, making overthinking worse. Opt for herbal teas and adequate hydration instead.

When to Seek Professional Help

If overthinking is persistent and starts interfering with your daily life—causing panic attacks, insomnia, or severe anxiety—it’s time to consult a doctor or therapist. Sometimes, professional guidance, counseling, or medical treatment is needed to restore balance.

Lab Tests That May Help

If you’re struggling with stress-related health issues, doctors may recommend tests like:

Complete Blood Count (CBC) – to check for immune cell levels
Vitamin D & B12 Tests – deficiencies worsen stress and fatigue
Thyroid Function Test – as thyroid imbalance can cause anxiety and fatigue
Cortisol Test – to assess stress hormone levels
Blood Sugar Test – since stress and overthinking may worsen diabetes risk

Final Thoughts

Your thoughts are powerful—they can either heal or harm your body. Overthinking may feel harmless, but it silently weakens your immune system, making you more vulnerable to infections and chronic illness. By practicing mindfulness, improving sleep, and balancing lifestyle habits, you can protect both your mental and physical health.

If you want to stay healthy and stress-free, start working on breaking the cycle of how overthinking affects your immune system today.

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