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Published on: Aug 30, 2021
2 minute read
By: Dr Rakesh Rai

What Are The Causes Of Liver Cirrhosis?

"What are the causes of liver cirrhosis?"

Several diseases can lead to cirrhosis of the liver, which is characterized by hardening and scarring to the organ's tissue. These include alcoholism, hepatitis C, chronic hepatitis B, and fatty liver disease.

Smoking, drinking too much alcohol, and hepatitis infection. Smoking and excessive drinking can lead to liver cirrhosis because they reduce the amount of oxygen and nutrients delivered to the liver. Smokers also have an increased risk of developing alcoholic hepatitis if they drink as well. Diseases such as chronic pancreatitis, a condition often caused by alcoholism, may also cause cirrhosis. Hepatitis infections are one prime example; people who will contract this type of virus have a greater likelihood of developing the liver disease later in life than those who haven't been exposed to it.

Cirrhosis is a condition that results when healthy cells inside the liver are replaced by scar tissue because of an injury, infection, or chronic disease. This eventually reduces the functionality of the organ and may eventually lead to liver failure, which in many cases can necessitate a transplant. Prevention and early detection for common conditions associated with liver cirrhosis should be pursued such as hepatitis B or C or Wilson’s Disease (a rare genetic disorder). Treatment options vary depending on the severity of cirrhosis but may include alcohol abstinence, medication to promote regeneration of diseased hepatocytes (specialized cells in the lining), surgery to remove any pools of blood/scar tissue from within the abdominal cavity that would otherwise compress other organs.

There are many possible causes, including genetics, diseases of the biliary tract system, drugs, and alcohol abuse. The cirrhotic liver has less elasticity than a typically healthy liver. This can lead to ruptured blood vessels within the organ that will cause bleeding into the cavity of the organ. The result of this bleeding is swelling and destruction of cells in that area; it's also called 'cirrhosis.' As cirrhosis progresses, there are limits to how much your damaged liver can work towards cleansing and detoxifying your body by removing poisons or toxins from the food you eat - because a damaged liver cannot produce enough bile that helps aid digestion.

There are many causes for liver cirrhosis, so it's not as though we can generalize. Some symptoms of liver damage include jaundice (yellowing skin) and frequent urination. Most signs of liver failure occur only in the advanced stages when the organ becomes too large to be compensated for by other organs or systems of the body. One should also note that alcohol is a primary cause of cirrhosis and often comes with other complications such as malnutrition, high blood pressure, and diabetes.

A) Symptoms of liver cirrhosis include jaundice, bruising easily, abnormal swelling in the legs and abdomen.

B) Hepatitis is a potential cause of liver cirrhosis.

C) Liver cancer can also produce symptoms related to liver cirrhosis such as enlarged lymph nodes or fluid buildup in the abdomen.

D) People who have eaten too much alcohol for many years are more likely to develop chronic alcohol abuse which destroys the cells on your liver causing it to stop functioning for good resulting in death. (this answer would be an ideal opportunity for advertising a medical consultation site but just mentioning their name could result in being reported)

E) Long-term exposure to viral hepatitis B or C

There are many causes of liver cirrhosis. Open sores on the skin, inflammation of the liver (cirrhosis), gall bladder problems, heavy drinking/overuse of alcohol, viral hepatitis, or other infections that cause scarring in the liver.

Liver cirrhosis is most often caused by chronic or acute alcoholism, drug abuse, hepatitis C, and other conditions that impair liver function. Liver cirrhosis causes your liver to be enlarged as its cells increase in number and fill up with fat. Liver cells normally work to get rid of any extra substances found in the blood and body fluids because these substances can cause damage to various organs including the liver. As diseased cells accumulate rapidly in the liver, they cannot do their job efficiently leading to additional organ damage such as end-stage renal disease. This whole process exposes you more easily to viruses such as hepatitis B and C which ultimately leads to advanced disease of the lungs called "cryptogenic pulmonary alveolar proteinosis".

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Impact of Air Pollution on Human Health: Risks, Effects and Prevention

Air pollution has become one of the most serious public health challenges worldwide. In India, rapid urbanisation, vehicle emissions, industrial activity and seasonal factors contribute to high pollution levels, especially in metropolitan cities. Understanding the impact of air pollution on human health is essential because exposure to polluted air significantly increases the risk of chronic illness and premature death.

According to the World Health Organization, air pollution is responsible for millions of premature deaths globally each year. Studies published in The Lancet highlight India as one of the countries most affected by air quality-related health burdens.

What Is Air Pollution?

Air pollution occurs when harmful substances such as:

particulate matter (PM2.5 and PM10)
nitrogen dioxide
sulfur dioxide
ozone
carbon monoxide

accumulate in the atmosphere at unsafe levels.

Among these, PM2.5 particles are particularly dangerous because they are small enough to penetrate deep into the lungs and bloodstream.

Respiratory Health Effects

The most immediate and visible impact of air pollution is on the lungs.

Short-Term Effects

coughing
throat irritation
wheezing
shortness of breath

Long-Term Effects

chronic bronchitis
asthma worsening
reduced lung capacity
chronic obstructive pulmonary disease (COPD)

Children and elderly individuals are especially vulnerable.

Impact on Heart Health

Air pollution does not only affect the lungs. Fine particles enter the bloodstream and trigger inflammation.

Long-term exposure increases risk of:

hypertension
heart attack
stroke
atherosclerosis

ICMR reports show cardiovascular diseases remain a leading cause of mortality in India, with pollution being a significant contributing factor.

Impact on Immune System

Constant exposure to polluted air weakens the immune response.

This leads to:

frequent respiratory infections
slower recovery from illness
increased susceptibility to viral diseases

Pollution also increases systemic inflammation.

Effect on Children’s Health

Children are particularly vulnerable because:

their lungs are still developing
they breathe more air relative to body weight
they spend time outdoors

Long-term exposure may reduce lung growth and increase asthma risk.

Impact on Pregnant Women and Infants

Research published in Lancet indicates that high pollution exposure during pregnancy increases risk of:

low birth weight
premature birth
developmental complications

Protecting pregnant women from pollution exposure is critical.

Air Pollution and Cancer Risk

Prolonged exposure to air pollution increases the risk of lung cancer.

WHO classifies outdoor air pollution as a carcinogen.

Mental Health and Cognitive Impact

Emerging research suggests pollution may contribute to:

cognitive decline
mood disorders
reduced concentration

Clean air supports brain health.

Seasonal Pollution in India

During winter months, many cities experience severe smog due to:

crop burning
temperature inversion
increased emissions

Monitoring Air Quality Index (AQI) helps individuals take precautions.

Signs of Pollution-Related Health Impact

persistent cough
chest tightness
eye irritation
unusual fatigue
worsening asthma

Individuals experiencing these symptoms should consult healthcare providers.

Preventive Measures to Reduce Exposure

Monitor AQI

Avoid outdoor activities during high pollution days.

Use Protective Masks

N95 masks filter fine particles effectively.

Indoor Air Quality

Use air purifiers and keep windows closed during peak pollution.

Avoid High-Traffic Areas

Limit time near busy roads.

Maintain Healthy Lifestyle

Strong immunity helps reduce pollution-related health risks.

Role of Preventive Healthcare

Regular screening for:

lung function
blood pressure
heart health

helps detect early damage caused by pollution.

Urban populations should prioritise routine health checkups.

Long-Term Public Health Impact

Air pollution contributes significantly to:

healthcare burden
productivity loss
economic strain

Preventive awareness and environmental policies are essential.

Conclusion

The impact of air pollution on human health is profound and far-reaching. From respiratory disorders and heart disease to immune suppression and increased cancer risk, polluted air affects nearly every organ system. In India’s urban environment, proactive measures such as monitoring AQI, using protective masks and maintaining regular health screenings are crucial. Protecting oneself from air pollution is not just about comfort—it is a vital step in preserving long-term health and preventing chronic disease.

References

World Health Organization (WHO) – Air Pollution and Health Reports
Indian Council of Medical Research (ICMR) – Environmental Health Studies
National Family Health Survey (NFHS-5) – Respiratory and Cardiovascular Data
NITI Aayog – Environmental and Preventive Health Strategy Reports
Lancet – Global Burden of Disease and Air Pollution Research

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