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Published on: Aug 18, 2022
2 minute read
By: Second Medic Expert

Understanding Liver Function Test

A liver function test is a blood test that measures the levels of various enzymes and proteins in your blood. These substances are produced by the liver, and they can be a sign of liver damage or disease.

There are a number of different liver function tests (LFTs) that can be used to assess the health of your liver. The most common ones are Bilirubin, Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST), and Alanine Transaminase (ALT).

Bilirubin is a pigment that is produced when the liver breaks down red blood cells. Elevated levels of bilirubin in the blood can be a sign of liver damage or disease.

ALP is an enzyme that is produced in the liver. High levels of ALP in the blood can indicate liver damage or disease.

There are a few different types of liver function tests, but they all basically measure the same thing: how well your liver is functioning. The most common liver function test is called the serum blood panel. This measures the levels of enzymes in your blood that are produced by the liver. These enzymes include:

- ALP (alkaline phosphatase): This enzyme helps with the digestion of fats and is increased when there is damage to the bile ducts.

- ALT (alanine transaminase): This enzyme helps with the breakdown of amino acids and is usually elevated when there is damage to hepatic cells.

- AST (aspartate aminotransferase):

The liver function test is a common medical test that is used to evaluate the health of your liver. The test measures levels of enzymes in your blood that are found mainly in the liver. Enzymes are proteins that help with chemical reactions in your body. When something is wrong with the liver, these enzymes can be released into the blood, where they can be detected by the Liver Function Test. Some of the things that can be checked with this test include hepatitis, cirrhosis, jaundice, and fatty liver disease. It can also give clues about other problems such as an toxins or alcoholism. The test is usually done as part of a routine checkup or when someone has symptoms that might be related to liver.

There are a few different liver function tests that your doctor may order, depending on your individual situation. These tests can help to assess how well your liver is functioning and whether or not there is any damage present.

There are a few different liver function tests (LFTs) that your doctor may order, depending on what they suspect might be going on with your liver. The most common LFT is the alanine transaminase (ALT) test. This measures the level of an enzyme called ALT in your blood. ALT is normally found in liver cells, so high levels of it in your blood can indicate liver damage. Other LFTs that may be ordered include the aspartate transaminase (AST) test, the alkaline phosphatase (ALP) test, and the gamma-glutamyl transferase (GGT) test. A liver function test is a blood test that measures the levels of enzymes in your blood. These enzymes are produced by your liver and help to break down fats, proteins, and carbohydrates. There are several different types of liver function tests, but the most common one is the alanine transaminase (ALT) test.

ALT is an enzyme that is involved in metabolizing amino acids. When your liver is damaged or inflamed, it releases Jazz hands advertising internships high levels of ALT into your bloodstream. The ALT test can be used to detect liver damage or disease. The normal range for ALT varies depending on your age and sex, but it is generally between 20 and 40 IU/L

There are a number of different liver function tests that can be performed, each of which can give useful information about the status of the liver. The most common liver function tests are the serum glycated albumin test, the serum alkaline phosphatase test, and the serum glutamic-oxaloacetic transaminase (SGOT)test.

The glycated albumin test measures the level of a specific type of sugar (glucose) that is bound to albumin, a protein found in the blood. This test provides an indication of how well the liver is able to process glucose.

The alkaline phosphatase test measures the level of an enzyme that is produced by the liver. This The liver function test is a blood test that measures the levels of certain enzymes and proteins in your liver. These substances are normally present in the liver in small amounts. But if your liver is damaged, these substances can leak into your bloodstream and increase the level of certain enzymes and proteins in your blood.

There are several different liver function tests, each of which measures different enzymes or proteins. The most common liver function tests are the alkaline phosphatase (ALP) test, the aspartate aminotransferase (AST) test, and the alanine aminotransferase (ALT) test.

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Difference Between Sadness and Depression: Understanding Normal Emotions vs Mental Illness

Feeling low or unhappy is a part of being human. However, not all low moods are the same. Many people confuse sadness with depression, which can delay proper support and treatment. Understanding the difference between sadness and depression is crucial for mental health awareness, early intervention and reducing stigma.

In India, mental health conditions are often misunderstood, with emotional distress frequently dismissed as temporary sadness.

What Is Sadness?

Sadness is a normal human emotion.

It usually occurs due to:

loss or disappointment
relationship issues
failure or stress
temporary life challenges

Sadness serves a psychological purpose, allowing individuals to process emotions and adapt.

Key Characteristics of Sadness

Sadness is:

situational
temporary
emotionally painful but manageable
responsive to support and positive events

A person experiencing sadness can still function, enjoy moments and feel hopeful.

What Is Depression?

Depression is a medical condition classified as a mood disorder.

It affects:

emotions
thinking patterns
behaviour
physical health

According to WHO, depression is one of the leading causes of disability worldwide.

Core Symptoms of Depression

Depression involves a combination of symptoms such as:

persistent low mood
loss of interest or pleasure
fatigue
sleep disturbances
appetite changes
feelings of worthlessness
difficulty concentrating

These symptoms last at least two weeks or longer.

Duration: A Key Difference

One major difference lies in duration.

Sadness:

lasts hours or days
improves with time

Depression:

lasts weeks or months
persists despite positive events

Duration helps distinguish emotional response from illness.

Impact on Daily Functioning

Sadness:

allows continuation of work and relationships
may reduce motivation temporarily

Depression:

interferes with work, studies and relationships
reduces self-care and productivity

Functional impairment is a defining feature of depression.

Emotional Experience: Sadness vs Depression

Sadness:

allows emotional range
moments of joy still occur

Depression:

creates emotional numbness
joy and interest disappear

People with depression often describe feeling empty rather than sad.

Physical Symptoms in Depression

Depression is not only emotional.

Physical symptoms include:

chronic fatigue
body aches
headaches
digestive issues

ICMR mental health studies highlight the physical burden of depression.

Thought Patterns and Self-Perception

Sadness:

thoughts remain realistic
self-worth is preserved

Depression:

negative self-talk dominates
feelings of guilt and worthlessness increase

These cognitive changes deepen emotional suffering.

Risk Factors for Depression

Factors increasing depression risk include:

chronic stress
trauma
family history
medical illnesses
hormonal changes

NFHS-5 data indicates rising mental health concerns among young adults.

Can Sadness Turn Into Depression?

Yes, prolonged or unresolved sadness can progress into depression.

This is more likely when:

stressors are ongoing
support systems are weak
coping mechanisms are limited

Early emotional support can prevent progression.

When to Seek Professional Help

Seek help if:

low mood lasts more than two weeks
daily functioning is affected
sleep and appetite are disturbed
thoughts of self-harm occur

Early care leads to better outcomes.

Treatment Differences

Sadness:

improves with rest, support and time

Depression:

requires psychotherapy
may need medication
benefits from structured care

WHO emphasises early treatment to reduce disability.

Role of Social Support

Support systems help both conditions but are essential for recovery.

Depression recovery improves with:

understanding family
supportive workplaces
accessible mental healthcare

Stigma reduction is key.

Mental Health Awareness in India

Mental health remains underdiagnosed in India.

NITI Aayog reports:

limited access to mental health services
low awareness
high stigma

Education helps bridge this gap.

Importance of Early Recognition

Recognising depression early:

prevents worsening
reduces suicide risk
improves quality of life

Delay increases suffering and complications.

Supporting Someone With Depression

Helpful actions include:

listening without judgement
encouraging professional help
avoiding minimising feelings

Compassion is more effective than advice.

Conclusion

Understanding the difference between sadness and depression is essential for emotional wellbeing and mental health care. Sadness is a natural, temporary response to life events, while depression is a serious medical condition that affects thoughts, emotions and daily functioning. Recognising the signs early and seeking appropriate help can prevent long-term suffering and promote recovery. Mental health deserves the same attention and care as physical health.

References

World Health Organization (WHO) – Depression and Mental Health Disorders
Indian Council of Medical Research (ICMR) – Mental Health Research and Burden
National Family Health Survey (NFHS-5) – Mental Health Indicators
Lancet – Depression, Disability and Public Health
NITI Aayog – National Mental Health Policy and Awareness Reports
Statista – Global and Indian Mental Health Trends

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