• Published on: Nov 10, 2021
  • 2 minute read
  • By: Second Medic Expert

Understanding Hemogram

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Understanding Hemogram

A hemogram can tell you a lot about your blood. For instance, red and white blood cells, as well as platelets (also called thrombocytes), will be counted and examined for size, shape, volume, and degree of organization. Specific factors that may affect these parameters include a total number of erythrocyte progenitor stem cells; RBC membrane stiffness; frequency of RBC production; distribution and frequency of phagocytosis (cellular breakdown); distribution and type of leukocytes (white blood cells) in circulation; vitamin deficiencies like folic acid or B12 deficiency. The number of toxic substances such as lead poisoning can also be analyzed from a hemogram.

Your hemoglobin levels should be high and your white cell count should be low. It's very important to have a blood test done when you're pregnant to make sure that you don't have any type of disease that the blood could transmit to the baby through the placenta, such as hepatitis B or C, HIV/AIDS, syphilis, or other diseases.

It's also important when giving birth if one is Rh-negative and hasn't been vaccinated against it (if they can't remember their past). If they were exposed in pregnancy and gave birth with an Rh-positive partner, there's a chance for their newborn baby to receive too many RBCs from mom and develop jaundice/anemia;

A hemogram is a blood test that measures the hematocrit, hemoglobin levels, and other substances in the blood (such as total protein and red blood cells). Hemograms can be differential or comprehensive. Comprehensive: performs a complete analysis of all forms of an organism's entire circulating cellular mass.  Differential: analyzes two sources from one specimen- for example, plasma and white cells, platelets and red cells, prothrombin time combined with partial thromboplastin time (PTT), D-dimer level with complete lipid profile to provide a clear diagnosis of possible metabolic liver problems.

A blood count measures the number of each type of cell found in one cubic millimeter (1/10th of a teaspoon) or 500 microliters (a little less than half a cup) of whole blood. The numbers are reported as cells per cubic millimeter, so you need to know how many millions there are to divide by 10 to get the actual headcount. In this way, for example, someone under 20 could have 1.0x1012 neutrophils and have a CBC that says they have 10x109 neutrophils per cubic millimeter."

The blood count may reveal, for example, an abnormally high number of red blood cells (confirmatory diagnosis) or determinations made by routine inspection that are not obvious without the additional information present in the hemogram. A hemogram is typically conducted to investigate an abnormal indication on a CBC. For instance, if you have very low white counts and no cause for this can be determined using other lab tests like a peripheral smear or bone marrow biopsy, it's possible that your doctor will perform a complete hemogram. Most often abnormalities are seen on the CBC.

When you're involved in extreme sports like skateboarding, your chances of getting injured are much greater than if you're at the pool or sipping tea. Hematoma is a condition that usually arises from some form of blunt force or direct trauma-related injury to the muscles and/or bones due to the high blood vessels around those areas. This injury can cause swelling which creates pressure on these vessels causing red blood cells to either leak into the soft tissue, tissues fluids, or even lead to a blocked flow of fresh oxygenated blood through these vessels if not treated promptly with an incision.

A hematocrit test analyzes the volume of red blood cells in one cubic millimeter of blood. Red blood cells contain hemoglobin, which carries oxygen and carbon dioxide to and from tissues and organs. The more severely an individual is afflicted with anemia, the lower the percentage of red blood cells they would have in one cubic millimeter of their own cardiac tissue.

If you endure a deep cut on your arm, your body will release stress hormones such as cortisol or epinephrine that prepare your immune system for increased levels of intense activity. These types of stress hormones also trigger a large release of iron from storage sites on red blood cells so that enough iron is available to help form new erythrocytes.

A haemogram is a study of the cellular inclusions in one's blood based on their shape, color, size, and specific gene expression. This process involves pumping a person's blood through a machine (this machine includes some spinning disks that separate out each type of cell for study). However, this test is not commonly done. Instead, analysis is usually limited to basic counts of red and white blood cells as well as platelets.

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Role of Nutrition in Disease Prevention: How Food Choices Shape Long-Term Health

Role of Nutrition in Disease Prevention: How Food Choices Shape Long-Term Health

Disease prevention is no longer limited to vaccinations and medical screenings. Modern healthcare increasingly recognises nutrition as one of the most powerful tools for preventing illness before it begins. The role of nutrition in disease prevention is especially important in India, where lifestyle-related diseases account for a large share of premature illness and mortality.

According to the Indian Council of Medical Research (ICMR) and the National Family Health Survey (NFHS-5), poor dietary patterns contribute significantly to rising cases of diabetes, heart disease, obesity and hypertension. Unlike genetic factors, nutrition is a modifiable risk factor, meaning everyday food choices can actively protect health.

 


Why Nutrition Is Central to Disease Prevention

1. Nutrition regulates metabolic health

Balanced diets help maintain:

  • healthy blood sugar levels
     

  • optimal cholesterol balance
     

  • stable blood pressure
     

Disruption in these systems increases disease risk.

2. Nutrition strengthens immunity

WHO highlights that immune function depends heavily on adequate intake of vitamins, minerals and protein.

3. Nutrition controls inflammation

Chronic low-grade inflammation is linked to most lifestyle diseases. Diets rich in whole foods reduce inflammatory markers.

Major Diseases Influenced by Nutrition

Diabetes and Prediabetes

Excess refined carbohydrates and sugar drive insulin resistance.

Preventive nutrition focuses on:

  • whole grains
     

  • fibre-rich vegetables
     

  • adequate protein
     

  • controlled portion sizes
     

ICMR data shows that dietary modification can delay or prevent type 2 diabetes in high-risk individuals.

Cardiovascular Disease

Heart disease remains a leading cause of death in India.

Nutrition impacts:

  • cholesterol levels
     

  • blood pressure
     

  • arterial inflammation
     

Diets low in trans fats and high in fibre significantly reduce cardiovascular risk, as confirmed by WHO and Lancet studies.

Obesity

Obesity increases the risk of multiple chronic diseases.

Preventive nutrition addresses:

  • calorie density
     

  • food quality
     

  • satiety regulation
     

NFHS-5 reports a steady rise in overweight and obesity across age groups.

Hypertension

High sodium intake and low potassium intake contribute to high blood pressure.

Preventive dietary strategies include:

  • reducing processed foods
     

  • increasing fruits and vegetables
     

  • maintaining mineral balance
     

Certain Cancers

Diet influences cancer risk through:

  • antioxidant intake
     

  • fibre consumption
     

  • reduced exposure to carcinogenic compounds
     

WHO estimates that a significant percentage of cancers are preventable through diet and lifestyle changes.

Key Nutrients That Support Disease Prevention

Fibre

Supports gut health, blood sugar control and cholesterol reduction.

Protein

Essential for muscle health, immune function and metabolic balance.

Healthy Fats

Omega-3 fats reduce inflammation and protect heart health.

Micronutrients

Iron, zinc, vitamin D and B vitamins are essential for metabolic and immune regulation.

NFHS-5 highlights widespread micronutrient deficiencies in India, increasing disease vulnerability.

Role of Gut Health in Prevention

The gut microbiome plays a major role in:

  • immune regulation
     

  • inflammation control
     

  • nutrient absorption
     

Fermented foods and fibre-rich diets support healthy gut bacteria, strengthening disease resistance.

 

Why Preventive Nutrition Works Best Early

Nutrition is most effective when applied:

  • before disease onset
     

  • during pre-disease stages
     

  • alongside regular health screening
     

Once disease progresses, nutrition remains supportive but may not reverse damage fully.

Nutrition vs Medication in Prevention

Medication treats disease; nutrition reduces risk.

WHO and NITI Aayog emphasize that:

  • preventive nutrition reduces disease incidence
     

  • lifestyle modification lowers healthcare burden
     

  • early nutrition changes reduce dependency on long-term medication
     

Both approaches work best when combined appropriately.

Workplace and Community Role in Preventive Nutrition

Structured nutrition programs at workplaces and communities:

  • improve awareness
     

  • support behaviour change
     

  • reduce population-level disease burden
     

Lancet studies show that group-based nutrition interventions improve long-term adherence.

 

Common Myths About Nutrition and Disease Prevention

Myth 1: Supplements replace healthy food

Whole foods provide better long-term protection.

Myth 2: Prevention requires extreme diets

Consistency matters more than restriction.

Myth 3: Nutrition only matters after diagnosis

Early nutrition is most effective before disease develops.

Building a Preventive Nutrition Routine

Effective preventive nutrition includes:

  • regular meals
     

  • diverse food groups
     

  • portion awareness
     

  • minimal processed foods
     

  • hydration
     

Small daily choices compound into long-term health benefits.

Long-Term Impact of Preventive Nutrition

Consistent healthy eating leads to:

  • reduced disease risk
     

  • improved energy and productivity
     

  • better immune resilience
     

  • lower healthcare costs
     

  • improved quality of life
     

NITI Aayog identifies nutrition as a cornerstone of sustainable healthcare systems.

Conclusion

Understanding the role of nutrition in disease prevention empowers individuals to take control of their health long before illness develops. Balanced, consistent nutrition reduces inflammation, supports immunity and protects against chronic diseases that burden India’s healthcare system. Preventive nutrition is not about short-term fixes but about building lifelong habits that support health, resilience and longevity.

 

References

  • ICMR – Nutrition and Lifestyle Disease Prevention Reports
     

  • National Family Health Survey (NFHS-5) – Dietary and Metabolic Health Data
     

  • NITI Aayog – Preventive Healthcare and Nutrition Strategy Reports
     

  • WHO – Diet, Nutrition and Chronic Disease Prevention Guidelines
     

  • Lancet – Nutrition and Disease Risk Reduction Studies
     

  • Statista – Dietary Trends and Health Outcomes India
     

  • EY-FICCI – Preventive Healthcare and Nutrition Economics

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