• Published on: Nov 10, 2021
  • 2 minute read
  • By: Second Medic Expert

Understanding Hemogram

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Understanding Hemogram

A hemogram can tell you a lot about your blood. For instance, red and white blood cells, as well as platelets (also called thrombocytes), will be counted and examined for size, shape, volume, and degree of organization. Specific factors that may affect these parameters include a total number of erythrocyte progenitor stem cells; RBC membrane stiffness; frequency of RBC production; distribution and frequency of phagocytosis (cellular breakdown); distribution and type of leukocytes (white blood cells) in circulation; vitamin deficiencies like folic acid or B12 deficiency. The number of toxic substances such as lead poisoning can also be analyzed from a hemogram.

Your hemoglobin levels should be high and your white cell count should be low. It's very important to have a blood test done when you're pregnant to make sure that you don't have any type of disease that the blood could transmit to the baby through the placenta, such as hepatitis B or C, HIV/AIDS, syphilis, or other diseases.

It's also important when giving birth if one is Rh-negative and hasn't been vaccinated against it (if they can't remember their past). If they were exposed in pregnancy and gave birth with an Rh-positive partner, there's a chance for their newborn baby to receive too many RBCs from mom and develop jaundice/anemia;

A hemogram is a blood test that measures the hematocrit, hemoglobin levels, and other substances in the blood (such as total protein and red blood cells). Hemograms can be differential or comprehensive. Comprehensive: performs a complete analysis of all forms of an organism's entire circulating cellular mass.  Differential: analyzes two sources from one specimen- for example, plasma and white cells, platelets and red cells, prothrombin time combined with partial thromboplastin time (PTT), D-dimer level with complete lipid profile to provide a clear diagnosis of possible metabolic liver problems.

A blood count measures the number of each type of cell found in one cubic millimeter (1/10th of a teaspoon) or 500 microliters (a little less than half a cup) of whole blood. The numbers are reported as cells per cubic millimeter, so you need to know how many millions there are to divide by 10 to get the actual headcount. In this way, for example, someone under 20 could have 1.0x1012 neutrophils and have a CBC that says they have 10x109 neutrophils per cubic millimeter."

The blood count may reveal, for example, an abnormally high number of red blood cells (confirmatory diagnosis) or determinations made by routine inspection that are not obvious without the additional information present in the hemogram. A hemogram is typically conducted to investigate an abnormal indication on a CBC. For instance, if you have very low white counts and no cause for this can be determined using other lab tests like a peripheral smear or bone marrow biopsy, it's possible that your doctor will perform a complete hemogram. Most often abnormalities are seen on the CBC.

When you're involved in extreme sports like skateboarding, your chances of getting injured are much greater than if you're at the pool or sipping tea. Hematoma is a condition that usually arises from some form of blunt force or direct trauma-related injury to the muscles and/or bones due to the high blood vessels around those areas. This injury can cause swelling which creates pressure on these vessels causing red blood cells to either leak into the soft tissue, tissues fluids, or even lead to a blocked flow of fresh oxygenated blood through these vessels if not treated promptly with an incision.

A hematocrit test analyzes the volume of red blood cells in one cubic millimeter of blood. Red blood cells contain hemoglobin, which carries oxygen and carbon dioxide to and from tissues and organs. The more severely an individual is afflicted with anemia, the lower the percentage of red blood cells they would have in one cubic millimeter of their own cardiac tissue.

If you endure a deep cut on your arm, your body will release stress hormones such as cortisol or epinephrine that prepare your immune system for increased levels of intense activity. These types of stress hormones also trigger a large release of iron from storage sites on red blood cells so that enough iron is available to help form new erythrocytes.

A haemogram is a study of the cellular inclusions in one's blood based on their shape, color, size, and specific gene expression. This process involves pumping a person's blood through a machine (this machine includes some spinning disks that separate out each type of cell for study). However, this test is not commonly done. Instead, analysis is usually limited to basic counts of red and white blood cells as well as platelets.

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Inflammation

How Inflammation Affects Overall Health: Understanding the Hidden Risks

Inflammation is often misunderstood. While it is a vital protective response of the immune system, persistent or chronic inflammation can quietly damage tissues and increase the risk of serious diseases. Understanding how inflammation affects overall health is crucial in preventing long-term complications and maintaining optimal wellbeing.

According to the World Health Organization and global medical research published in Lancet, chronic inflammation is linked to a wide range of non-communicable diseases, including heart disease, diabetes and autoimmune disorders.

 

What Is Inflammation?

Inflammation is the body’s natural response to:

  • infection

  • injury

  • toxins

  • stress

It activates immune cells to eliminate harmful stimuli and promote healing.

There are two main types:

Acute Inflammation

Short-term and protective.
Examples include swelling after injury or fever during infection.

Chronic Inflammation

Long-term, low-grade inflammation that persists even without injury.

Chronic inflammation is harmful.

 

How Chronic Inflammation Develops

Persistent inflammation can result from:

  • unhealthy diet

  • sedentary lifestyle

  • obesity

  • chronic stress

  • environmental toxins

  • untreated infections

Modern lifestyle patterns contribute significantly to this condition.

 

Impact on Heart Health

Inflammation damages blood vessels and promotes plaque formation.

This increases risk of:

  • heart attack

  • stroke

  • hypertension

ICMR data highlights cardiovascular disease as a leading cause of death in India, with inflammation playing a contributing role.

 

Link Between Inflammation and Diabetes

Chronic inflammation interferes with insulin signalling.

This leads to:

  • insulin resistance

  • elevated blood sugar

  • metabolic syndrome

NFHS-5 data shows rising diabetes prevalence, partly linked to inflammatory lifestyle factors.

 

Effect on Joint and Muscle Health

Inflammatory processes contribute to:

  • arthritis

  • joint stiffness

  • muscle pain

Autoimmune diseases often involve chronic inflammation.

 

Gut Health and Inflammation

The gut plays a central role in immune regulation.

Poor diet and stress disrupt gut balance, triggering:

  • inflammatory bowel conditions

  • digestive discomfort

  • nutrient malabsorption

Gut inflammation impacts systemic health.

 

Brain Health and Inflammation

Emerging research suggests chronic inflammation affects:

  • memory

  • mood

  • cognitive performance

Inflammatory markers are associated with depression and neurodegenerative disorders.

 

Chronic Fatigue and Inflammatory Stress

Persistent inflammation causes:

  • ongoing fatigue

  • reduced stamina

  • sleep disturbances

The immune system remains in constant activation mode.

 

Role in Autoimmune Disorders

Autoimmune diseases occur when the immune system mistakenly attacks healthy tissues.

Chronic inflammation is central to conditions such as:

  • rheumatoid arthritis

  • lupus

  • inflammatory bowel disease

 

Signs of Chronic Inflammation

Symptoms may include:

  • unexplained fatigue

  • persistent joint pain

  • digestive issues

  • frequent infections

  • skin problems

Early detection is important.

 

Lifestyle Factors That Increase Inflammation

High Sugar Intake

Excess sugar promotes inflammatory pathways.

 

Processed Foods

Trans fats and additives trigger immune responses.

 

Sedentary Lifestyle

Lack of exercise reduces anti-inflammatory benefits.

 

Poor Sleep

Sleep deprivation increases inflammatory markers.

 

Chronic Stress

Elevated cortisol disrupts immune balance.

 

Natural Ways to Reduce Inflammation

Anti-Inflammatory Diet

Include:

  • leafy greens

  • fruits rich in antioxidants

  • nuts and seeds

  • whole grains

Avoid excessive processed foods.

 

Regular Physical Activity

Exercise lowers inflammatory markers and improves circulation.

 

Stress Management

Meditation and breathing exercises reduce stress hormones.

 

Adequate Sleep

7–8 hours of quality sleep supports immune regulation.

 

Maintain Healthy Weight

Excess abdominal fat produces inflammatory chemicals.

 

Role of Preventive Health Screening

Regular tests such as:

  • blood sugar

  • lipid profile

  • inflammatory markers

help monitor risk factors early.

 

Importance of Early Intervention

Unchecked inflammation increases risk of:

  • cardiovascular disease

  • metabolic disorders

  • organ damage

Timely lifestyle changes reverse early inflammatory effects.

 

Long-Term Health Benefits of Inflammation Control

Reducing inflammation supports:

  • heart health

  • stable blood sugar

  • improved immunity

  • enhanced cognitive function

  • reduced pain

Preventive strategies protect long-term wellbeing.

 

Conclusion

Understanding how inflammation affects overall health reveals its profound impact on the heart, brain, gut and metabolic systems. While acute inflammation protects the body, chronic inflammation silently contributes to major diseases. Fortunately, lifestyle changes such as balanced nutrition, regular exercise, quality sleep and stress management significantly reduce inflammatory burden. Prevention and early monitoring remain the most effective tools for protecting overall health and ensuring long-term vitality.

 

References

  • World Health Organization (WHO) – Chronic Disease and Inflammation Reports

  • Indian Council of Medical Research (ICMR) – Cardiovascular and Metabolic Health Studies

  • National Family Health Survey (NFHS-5) – Diabetes and Hypertension Data

  • NITI Aayog – Preventive Healthcare Strategy Reports

  • Lancet – Inflammation and Chronic Disease Research

See all

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