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Published on: Nov 10, 2021
2 minute read
By: Second Medic Expert

Understanding Hemogram

A hemogram can tell you a lot about your blood. For instance, red and white blood cells, as well as platelets (also called thrombocytes), will be counted and examined for size, shape, volume, and degree of organization. Specific factors that may affect these parameters include a total number of erythrocyte progenitor stem cells; RBC membrane stiffness; frequency of RBC production; distribution and frequency of phagocytosis (cellular breakdown); distribution and type of leukocytes (white blood cells) in circulation; vitamin deficiencies like folic acid or B12 deficiency. The number of toxic substances such as lead poisoning can also be analyzed from a hemogram.

Your hemoglobin levels should be high and your white cell count should be low. It's very important to have a blood test done when you're pregnant to make sure that you don't have any type of disease that the blood could transmit to the baby through the placenta, such as hepatitis B or C, HIV/AIDS, syphilis, or other diseases.

It's also important when giving birth if one is Rh-negative and hasn't been vaccinated against it (if they can't remember their past). If they were exposed in pregnancy and gave birth with an Rh-positive partner, there's a chance for their newborn baby to receive too many RBCs from mom and develop jaundice/anemia;

A hemogram is a blood test that measures the hematocrit, hemoglobin levels, and other substances in the blood (such as total protein and red blood cells). Hemograms can be differential or comprehensive. Comprehensive: performs a complete analysis of all forms of an organism's entire circulating cellular mass. Differential: analyzes two sources from one specimen- for example, plasma and white cells, platelets and red cells, prothrombin time combined with partial thromboplastin time (PTT), D-dimer level with complete lipid profile to provide a clear diagnosis of possible metabolic liver problems.

A blood count measures the number of each type of cell found in one cubic millimeter (1/10th of a teaspoon) or 500 microliters (a little less than half a cup) of whole blood. The numbers are reported as cells per cubic millimeter, so you need to know how many millions there are to divide by 10 to get the actual headcount. In this way, for example, someone under 20 could have 1.0x1012 neutrophils and have a CBC that says they have 10x109 neutrophils per cubic millimeter."

The blood count may reveal, for example, an abnormally high number of red blood cells (confirmatory diagnosis) or determinations made by routine inspection that are not obvious without the additional information present in the hemogram. A hemogram is typically conducted to investigate an abnormal indication on a CBC. For instance, if you have very low white counts and no cause for this can be determined using other lab tests like a peripheral smear or bone marrow biopsy, it's possible that your doctor will perform a complete hemogram. Most often abnormalities are seen on the CBC.

When you're involved in extreme sports like skateboarding, your chances of getting injured are much greater than if you're at the pool or sipping tea. Hematoma is a condition that usually arises from some form of blunt force or direct trauma-related injury to the muscles and/or bones due to the high blood vessels around those areas. This injury can cause swelling which creates pressure on these vessels causing red blood cells to either leak into the soft tissue, tissues fluids, or even lead to a blocked flow of fresh oxygenated blood through these vessels if not treated promptly with an incision.

A hematocrit test analyzes the volume of red blood cells in one cubic millimeter of blood. Red blood cells contain hemoglobin, which carries oxygen and carbon dioxide to and from tissues and organs. The more severely an individual is afflicted with anemia, the lower the percentage of red blood cells they would have in one cubic millimeter of their own cardiac tissue.

If you endure a deep cut on your arm, your body will release stress hormones such as cortisol or epinephrine that prepare your immune system for increased levels of intense activity. These types of stress hormones also trigger a large release of iron from storage sites on red blood cells so that enough iron is available to help form new erythrocytes.

A haemogram is a study of the cellular inclusions in one's blood based on their shape, color, size, and specific gene expression. This process involves pumping a person's blood through a machine (this machine includes some spinning disks that separate out each type of cell for study). However, this test is not commonly done. Instead, analysis is usually limited to basic counts of red and white blood cells as well as platelets.

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How Cold Weather Affects Health: Understanding Winter’s Impact on the Body

Seasonal changes influence human health more than most people realise. Cold weather, in particular, places unique stress on the body and can worsen existing health conditions while increasing susceptibility to new illnesses. Understanding how cold weather affects health is essential for preventing seasonal complications and maintaining wellbeing during winter months.

In India, winter-related health issues vary by region but commonly include respiratory infections, cardiovascular strain and joint discomfort. According to the Indian Council of Medical Research (ICMR) and World Health Organization (WHO), cold exposure is associated with increased morbidity, especially among older adults and people with chronic conditions.

Why Cold Weather Impacts the Body

The human body works constantly to maintain core temperature. In cold environments:

blood vessels constrict to conserve heat
energy expenditure increases
immune responses may weaken
organs work harder to maintain balance

These adaptations, while protective, also create health vulnerabilities.

Increased Risk of Infections

Weakened Immune Response

Cold weather can suppress immune function, making it harder for the body to fight infections.

Factors contributing to winter infections include:

reduced vitamin D due to less sunlight
dry air affecting mucosal defenses
closer indoor contact

Common winter infections include colds, flu and respiratory illnesses.

Respiratory Health Problems

Cold air irritates the respiratory tract.

This can lead to:

worsening asthma symptoms
bronchitis flare-ups
increased cough and breathlessness

WHO reports higher hospital admissions for respiratory illnesses during colder months.

Impact on Heart Health

Cold temperatures affect cardiovascular function.

Blood Vessel Constriction

Cold causes blood vessels to narrow, increasing:

blood pressure
heart workload

This raises the risk of:

heart attacks
strokes

People with existing heart disease are particularly vulnerable.

Joint and Muscle Pain

Cold weather affects musculoskeletal health.

Common complaints include:

joint stiffness
muscle aches
worsening arthritis pain

Lower temperatures reduce joint lubrication and increase sensitivity to pain.

Metabolic and Weight Changes

Winter often leads to:

reduced physical activity
increased calorie intake
metabolic slowdown

These changes contribute to weight gain and worsen metabolic conditions such as diabetes.

Skin and Hydration Issues

Cold air holds less moisture.

This leads to:

dry skin
cracked lips
worsening eczema

Dehydration is also common as thirst perception reduces in cold weather.

Mental Health Effects

Seasonal changes can influence mental wellbeing.

Cold weather is associated with:

low mood
reduced motivation
seasonal affective symptoms

Limited sunlight affects circadian rhythm and serotonin levels.

Cold Weather and Older Adults

Elderly individuals face higher risks due to:

reduced temperature regulation
weaker immunity
existing chronic conditions

Winter-related complications are a significant cause of hospitalisation in older populations.

Why Chronic Diseases Worsen in Winter

Conditions such as:

hypertension
arthritis
asthma
diabetes

often worsen due to reduced activity, stress on organs and infection risk.

Preventive Strategies for Winter Health

Maintain Body Warmth

Layered clothing and warm environments reduce cold stress.

Support Immunity

Adequate nutrition, vitamin intake and sleep strengthen immune defences.

Stay Physically Active

Indoor exercises and regular movement prevent stiffness and metabolic decline.

Manage Chronic Conditions

Regular monitoring and medication adherence are critical during winter.

Hydration and Skin Care

Drinking fluids and using moisturisers prevent dehydration and skin damage.

Role of Preventive Healthcare

Preventive healthcare helps:

identify seasonal risk factors
adjust treatment plans
prevent winter complications

NITI Aayog highlights seasonal preparedness as an important public health strategy.

When to Seek Medical Help

Medical attention is necessary if:

infections persist or worsen
chest pain or breathlessness occurs
joint pain limits mobility
mental health symptoms interfere with daily life

Early care prevents serious outcomes.

Long-Term Impact of Ignoring Winter Health Risks

Ignoring cold weather effects may lead to:

severe infections
cardiovascular events
chronic pain progression
reduced quality of life

Seasonal awareness plays a critical role in long-term health.

Conclusion

Understanding how cold weather affects health allows individuals to take timely preventive measures. Winter increases the risk of infections, heart strain, respiratory problems, joint pain and mental health challenges. With proper warmth, nutrition, activity and preventive healthcare, most cold-related health issues are manageable and preventable. Seasonal care is not optional—it is essential for protecting health and wellbeing throughout the colder months.

References

ICMR – Seasonal Health and Infectious Disease Reports
National Family Health Survey (NFHS-5) – Seasonal Morbidity Data
NITI Aayog – Preventive Healthcare and Seasonal Preparedness Strategy
WHO – Cold Weather and Health Impact Guideline
Lancet – Seasonal Variation in Cardiovascular and Respiratory Diseases
Statista – Winter Health Trends and Illness Data
Indian Journal of Public Health – Climate and Health Studies

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