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Published on: Nov 10, 2021
2 minute read
By: Second Medic Expert

Understanding Hemogram

A hemogram can tell you a lot about your blood. For instance, red and white blood cells, as well as platelets (also called thrombocytes), will be counted and examined for size, shape, volume, and degree of organization. Specific factors that may affect these parameters include a total number of erythrocyte progenitor stem cells; RBC membrane stiffness; frequency of RBC production; distribution and frequency of phagocytosis (cellular breakdown); distribution and type of leukocytes (white blood cells) in circulation; vitamin deficiencies like folic acid or B12 deficiency. The number of toxic substances such as lead poisoning can also be analyzed from a hemogram.

Your hemoglobin levels should be high and your white cell count should be low. It's very important to have a blood test done when you're pregnant to make sure that you don't have any type of disease that the blood could transmit to the baby through the placenta, such as hepatitis B or C, HIV/AIDS, syphilis, or other diseases.

It's also important when giving birth if one is Rh-negative and hasn't been vaccinated against it (if they can't remember their past). If they were exposed in pregnancy and gave birth with an Rh-positive partner, there's a chance for their newborn baby to receive too many RBCs from mom and develop jaundice/anemia;

A hemogram is a blood test that measures the hematocrit, hemoglobin levels, and other substances in the blood (such as total protein and red blood cells). Hemograms can be differential or comprehensive. Comprehensive: performs a complete analysis of all forms of an organism's entire circulating cellular mass. Differential: analyzes two sources from one specimen- for example, plasma and white cells, platelets and red cells, prothrombin time combined with partial thromboplastin time (PTT), D-dimer level with complete lipid profile to provide a clear diagnosis of possible metabolic liver problems.

A blood count measures the number of each type of cell found in one cubic millimeter (1/10th of a teaspoon) or 500 microliters (a little less than half a cup) of whole blood. The numbers are reported as cells per cubic millimeter, so you need to know how many millions there are to divide by 10 to get the actual headcount. In this way, for example, someone under 20 could have 1.0x1012 neutrophils and have a CBC that says they have 10x109 neutrophils per cubic millimeter."

The blood count may reveal, for example, an abnormally high number of red blood cells (confirmatory diagnosis) or determinations made by routine inspection that are not obvious without the additional information present in the hemogram. A hemogram is typically conducted to investigate an abnormal indication on a CBC. For instance, if you have very low white counts and no cause for this can be determined using other lab tests like a peripheral smear or bone marrow biopsy, it's possible that your doctor will perform a complete hemogram. Most often abnormalities are seen on the CBC.

When you're involved in extreme sports like skateboarding, your chances of getting injured are much greater than if you're at the pool or sipping tea. Hematoma is a condition that usually arises from some form of blunt force or direct trauma-related injury to the muscles and/or bones due to the high blood vessels around those areas. This injury can cause swelling which creates pressure on these vessels causing red blood cells to either leak into the soft tissue, tissues fluids, or even lead to a blocked flow of fresh oxygenated blood through these vessels if not treated promptly with an incision.

A hematocrit test analyzes the volume of red blood cells in one cubic millimeter of blood. Red blood cells contain hemoglobin, which carries oxygen and carbon dioxide to and from tissues and organs. The more severely an individual is afflicted with anemia, the lower the percentage of red blood cells they would have in one cubic millimeter of their own cardiac tissue.

If you endure a deep cut on your arm, your body will release stress hormones such as cortisol or epinephrine that prepare your immune system for increased levels of intense activity. These types of stress hormones also trigger a large release of iron from storage sites on red blood cells so that enough iron is available to help form new erythrocytes.

A haemogram is a study of the cellular inclusions in one's blood based on their shape, color, size, and specific gene expression. This process involves pumping a person's blood through a machine (this machine includes some spinning disks that separate out each type of cell for study). However, this test is not commonly done. Instead, analysis is usually limited to basic counts of red and white blood cells as well as platelets.

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Health Problems Linked to Excessive Caffeine Intake: When Too Much Becomes Harmful

Caffeine is one of the most widely consumed stimulants in the world. Found in coffee, tea, energy drinks and many soft drinks, it is often used to improve alertness and combat fatigue. While moderate caffeine consumption can be safe for most people, understanding the health problems linked to excessive caffeine intake is important, especially as daily consumption levels continue to rise in India.

Urban lifestyles, long working hours and increased reliance on energy drinks have made caffeine overconsumption a growing public health concern.

How Caffeine Works in the Body

Caffeine stimulates the central nervous system by blocking adenosine, a chemical responsible for promoting sleep and relaxation.

This results in:

increased alertness
faster heart rate
heightened mental activity

However, overstimulation places stress on multiple body systems.

What Is Considered Excessive Caffeine Intake?

According to WHO and global health guidelines:

up to 400 mg per day is considered safe for most healthy adults

Excessive intake occurs when:

multiple caffeinated beverages are consumed daily
energy drinks are used frequently
caffeine is consumed late in the day

Many people unknowingly exceed safe limits.

Nervous System Overstimulation

Excess caffeine overstimulates the brain.

Common symptoms include:

restlessness
nervousness
tremors
irritability

Chronic overstimulation can worsen stress and reduce emotional stability.

Anxiety and Panic Symptoms

Caffeine increases adrenaline release.

This can:

trigger anxiety attacks
worsen panic disorder
increase feelings of unease

ICMR mental health studies note caffeine as a common trigger for anxiety symptoms in sensitive individuals.

Sleep Disruption and Insomnia

Sleep is one of the first systems affected.

Excessive caffeine:

delays sleep onset
reduces deep sleep
shortens total sleep duration

Even caffeine consumed 6–8 hours before bedtime can impair sleep quality.

Impact on Heart Health

High caffeine intake affects the cardiovascular system.

Possible effects include:

increased heart rate
palpitations
irregular heart rhythm

People with underlying heart conditions are particularly vulnerable.

Blood Pressure Elevation

Caffeine temporarily raises blood pressure.

Chronic excessive intake may:

worsen hypertension
increase cardiovascular risk

NFHS-5 data highlights rising hypertension prevalence in India, making caffeine moderation important.

Digestive System Problems

Caffeine stimulates stomach acid production.

This can cause:

acidity
heartburn
gastritis
bloating

People with sensitive digestion may experience symptoms even at lower doses.

Dependency and Withdrawal Symptoms

Regular high intake leads to caffeine dependence.

Withdrawal symptoms include:

headaches
fatigue
irritability
difficulty concentrating

Dependence reinforces overconsumption cycles.

Effect on Bone Health

Excessive caffeine:

increases calcium loss through urine
may affect bone density over time

This is particularly concerning for older adults and women.

Dehydration and Electrolyte Imbalance

Caffeine has a mild diuretic effect.

High intake without adequate hydration may lead to:

dehydration
muscle cramps
fatigue

Hot climates increase this risk.

Impact on Blood Sugar and Metabolism

Caffeine affects glucose metabolism.

Excessive intake:

worsens insulin sensitivity
increases stress hormone release

This may increase diabetes risk when combined with poor lifestyle habits.

Energy Drinks and Hidden Risks

Energy drinks often contain:

very high caffeine levels
added sugar
stimulants

Lancet reports associate energy drink overuse with heart rhythm disturbances and metabolic stress.

High-Risk Groups

Certain individuals should be especially cautious:

people with anxiety disorders
those with heart disease
pregnant women
individuals with sleep disorders

Safe limits may be lower for these groups.

Signs You May Be Consuming Too Much Caffeine

Warning signs include:

frequent palpitations
chronic insomnia
persistent anxiety
digestive discomfort
reliance on caffeine to function

These signals indicate the need for reduction.

How to Reduce Caffeine Intake Safely

Effective strategies include:

gradual reduction rather than abrupt stopping
switching to decaffeinated options
avoiding caffeine after mid-afternoon
improving sleep and nutrition

Small steps prevent withdrawal symptoms.

Healthier Alternatives for Energy

Better ways to improve energy include:

adequate sleep
balanced meals
hydration
regular physical activity

These support sustained energy without overstimulation.

Role of Preventive Health Awareness

Preventive healthcare focuses on:

identifying lifestyle triggers
reducing dependency habits

NITI Aayog highlights lifestyle modification as key to non-communicable disease prevention.

Long-Term Health Consequences of Ignoring Excess Intake

Chronic caffeine overuse increases risk of:

sleep disorders
anxiety and mood issues
heart rhythm problems
digestive disorders

These conditions often develop gradually.

Conclusion

The health problems linked to excessive caffeine intake extend beyond temporary jitters or sleep loss. Chronic overconsumption strains the nervous system, disrupts sleep, affects heart rhythm, worsens anxiety and impacts digestion and metabolism. While caffeine can be enjoyed safely in moderation, recognising personal limits and maintaining balance is essential for long-term health. Listening to early warning signs and adopting healthier energy habits can prevent serious health consequences.

References

World Health Organization (WHO) – Caffeine Intake and Health Guidelines
Indian Council of Medical Research (ICMR) – Nutrition and Mental Health Studies
National Family Health Survey (NFHS-5) – Hypertension and Lifestyle Risk Data
Lancet – Energy Drinks, Caffeine and Cardiovascular Effects
NITI Aayog – Preventive Health and Lifestyle Modification Reports
Statista – Caffeine Consumption Trends in India

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