• Published on: Nov 10, 2021
  • 2 minute read
  • By: Second Medic Expert

Understanding Hemogram

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Understanding Hemogram

A hemogram can tell you a lot about your blood. For instance, red and white blood cells, as well as platelets (also called thrombocytes), will be counted and examined for size, shape, volume, and degree of organization. Specific factors that may affect these parameters include a total number of erythrocyte progenitor stem cells; RBC membrane stiffness; frequency of RBC production; distribution and frequency of phagocytosis (cellular breakdown); distribution and type of leukocytes (white blood cells) in circulation; vitamin deficiencies like folic acid or B12 deficiency. The number of toxic substances such as lead poisoning can also be analyzed from a hemogram.

Your hemoglobin levels should be high and your white cell count should be low. It's very important to have a blood test done when you're pregnant to make sure that you don't have any type of disease that the blood could transmit to the baby through the placenta, such as hepatitis B or C, HIV/AIDS, syphilis, or other diseases.

It's also important when giving birth if one is Rh-negative and hasn't been vaccinated against it (if they can't remember their past). If they were exposed in pregnancy and gave birth with an Rh-positive partner, there's a chance for their newborn baby to receive too many RBCs from mom and develop jaundice/anemia;

A hemogram is a blood test that measures the hematocrit, hemoglobin levels, and other substances in the blood (such as total protein and red blood cells). Hemograms can be differential or comprehensive. Comprehensive: performs a complete analysis of all forms of an organism's entire circulating cellular mass.  Differential: analyzes two sources from one specimen- for example, plasma and white cells, platelets and red cells, prothrombin time combined with partial thromboplastin time (PTT), D-dimer level with complete lipid profile to provide a clear diagnosis of possible metabolic liver problems.

A blood count measures the number of each type of cell found in one cubic millimeter (1/10th of a teaspoon) or 500 microliters (a little less than half a cup) of whole blood. The numbers are reported as cells per cubic millimeter, so you need to know how many millions there are to divide by 10 to get the actual headcount. In this way, for example, someone under 20 could have 1.0x1012 neutrophils and have a CBC that says they have 10x109 neutrophils per cubic millimeter."

The blood count may reveal, for example, an abnormally high number of red blood cells (confirmatory diagnosis) or determinations made by routine inspection that are not obvious without the additional information present in the hemogram. A hemogram is typically conducted to investigate an abnormal indication on a CBC. For instance, if you have very low white counts and no cause for this can be determined using other lab tests like a peripheral smear or bone marrow biopsy, it's possible that your doctor will perform a complete hemogram. Most often abnormalities are seen on the CBC.

When you're involved in extreme sports like skateboarding, your chances of getting injured are much greater than if you're at the pool or sipping tea. Hematoma is a condition that usually arises from some form of blunt force or direct trauma-related injury to the muscles and/or bones due to the high blood vessels around those areas. This injury can cause swelling which creates pressure on these vessels causing red blood cells to either leak into the soft tissue, tissues fluids, or even lead to a blocked flow of fresh oxygenated blood through these vessels if not treated promptly with an incision.

A hematocrit test analyzes the volume of red blood cells in one cubic millimeter of blood. Red blood cells contain hemoglobin, which carries oxygen and carbon dioxide to and from tissues and organs. The more severely an individual is afflicted with anemia, the lower the percentage of red blood cells they would have in one cubic millimeter of their own cardiac tissue.

If you endure a deep cut on your arm, your body will release stress hormones such as cortisol or epinephrine that prepare your immune system for increased levels of intense activity. These types of stress hormones also trigger a large release of iron from storage sites on red blood cells so that enough iron is available to help form new erythrocytes.

A haemogram is a study of the cellular inclusions in one's blood based on their shape, color, size, and specific gene expression. This process involves pumping a person's blood through a machine (this machine includes some spinning disks that separate out each type of cell for study). However, this test is not commonly done. Instead, analysis is usually limited to basic counts of red and white blood cells as well as platelets.

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Asthma

Asthma Symptoms in Adults: Early Signs, Triggers, and When to Seek Care

Asthma is often perceived as a childhood condition, but a significant number of cases develop or persist into adulthood. In India, adult asthma is increasingly recognised due to rising air pollution, occupational exposure and lifestyle-related risk factors. Unfortunately, asthma symptoms in adults are frequently misdiagnosed as recurrent infections, allergies or age-related breathlessness, leading to delayed treatment.

Understanding adult asthma symptoms is critical for early diagnosis, effective control and prevention of severe attacks.

 

What Is Asthma?

Asthma is a chronic inflammatory disease of the airways. In asthma, the airways become:

  • inflamed
     

  • narrow
     

  • overly sensitive to triggers
     

This leads to difficulty in breathing, especially during exposure to specific stimuli.

 

Why Adult Asthma Is Often Missed

Adult asthma symptoms may:

  • appear gradually
     

  • vary in severity
     

  • mimic common respiratory conditions
     

According to Indian Council of Medical Research and WHO data, many adults remain undiagnosed for years, increasing the risk of complications.

 

Common Asthma Symptoms in Adults

Wheezing

A high-pitched whistling sound while breathing, especially during exhalation, is a classic asthma sign.

 

Shortness of Breath

Adults with asthma often feel:

  • breathless during routine activities
     

  • difficulty taking deep breaths
     

This may worsen at night or early morning.

 

Chest Tightness

Many describe a sensation of pressure or tightness in the chest, which can be mistaken for heart-related issues.

 

Chronic Cough

A persistent cough, especially:

  • at night
     

  • early morning
     

  • after exercise
     

is a common but overlooked asthma symptom.

 

Symptoms That Worsen With Triggers

Asthma symptoms often intensify after exposure to specific triggers.

Air Pollution and Smoke

Urban pollution, vehicle emissions and indoor smoke significantly worsen asthma symptoms in adults.

 

Allergens

Dust mites, pollen, mould and pet dander are common triggers.

 

Respiratory Infections

Viral infections can trigger asthma flare-ups or reveal undiagnosed asthma.

 

Physical Activity

Exercise-induced asthma causes breathlessness and wheezing during or after physical exertion.

 

Weather Changes

Cold air, humidity and sudden temperature changes can aggravate symptoms.

 

Adult-Onset Asthma

Adult-onset asthma differs from childhood asthma.

Characteristics include:

  • onset after age 20–30
     

  • less association with childhood allergies
     

  • more persistent symptoms
     

  • higher likelihood of severe disease
     

Occupational exposure and hormonal changes contribute to adult-onset asthma.

 

Risk Factors for Asthma in Adults

Several factors increase asthma risk:

  • long-term exposure to pollution
     

  • smoking or passive smoking
     

  • occupational chemicals or dust
     

  • obesity
     

  • family history of asthma
     

  • chronic sinusitis or allergies
     

Women may experience asthma onset or worsening during hormonal changes.

 

When Asthma Symptoms Become Serious

Seek immediate medical attention if experiencing:

  • severe breathlessness
     

  • difficulty speaking in full sentences
     

  • bluish lips or fingertips
     

  • rapid worsening of symptoms
     

  • poor response to usual inhalers
     

These signs indicate a potentially life-threatening asthma attack.

 

How Adult Asthma Is Diagnosed

Diagnosis includes:

  • detailed symptom history
     

  • physical examination
     

  • lung function tests (spirometry)
     

  • response to bronchodilators
     

Early diagnosis improves long-term outcomes.

 

Impact of Untreated Asthma

Untreated asthma can lead to:

  • frequent attacks
     

  • reduced lung function
     

  • sleep disturbances
     

  • missed workdays
     

  • reduced quality of life
     

According to Lancet respiratory studies, uncontrolled asthma increases hospitalisation risk.

 

Managing Asthma Symptoms in Adults

Effective asthma management focuses on:

  • identifying and avoiding triggers
     

  • using prescribed inhalers correctly
     

  • monitoring symptoms regularly
     

  • maintaining follow-up care
     

Asthma action plans help patients recognise worsening symptoms early.

 

Role of Preventive Healthcare

Preventive healthcare helps:

  • detect asthma early
     

  • assess lung function
     

  • guide lifestyle modifications
     

Regular health checkups are especially important for individuals with respiratory symptoms or occupational exposure.

 

Lifestyle Measures That Support Asthma Control

Helpful practices include:

  • avoiding smoking
     

  • improving indoor air quality
     

  • wearing masks in polluted environments
     

  • maintaining healthy weight
     

  • regular, moderate exercise
     

Lifestyle support complements medical treatment.

 

Mental Health and Asthma

Stress and anxiety can worsen asthma symptoms.

Stress management:

  • reduces symptom frequency
     

  • improves medication response
     

Holistic care improves asthma outcomes.

 

Importance of Medication Adherence

Asthma medications work best when:

  • taken regularly as prescribed
     

  • inhaler technique is correct
     

Skipping treatment increases flare-up risk.

 

Long-Term Outlook for Adults With Asthma

With proper management:

  • symptoms are well controlled
     

  • severe attacks are preventable
     

  • normal activity levels are achievable
     

Most adults with asthma lead active, productive lives.

 

Conclusion

Asthma symptoms in adults are often subtle, variable and easily mistaken for common respiratory problems. Wheezing, breathlessness, chest tightness and chronic cough should not be ignored, especially when triggered by pollution, exercise or weather changes. Early diagnosis, trigger control and consistent treatment are essential to prevent severe attacks and preserve lung health. Recognising adult asthma early empowers individuals to manage symptoms effectively and maintain a good quality of life.

 

References

  • Indian Council of Medical Research (ICMR) – Respiratory Disease and Asthma Studies
  • World Health Organization (WHO) – Asthma Management and Prevention Guidelines
  • National Family Health Survey (NFHS-5) – Respiratory Health Indicators
  • Lancet Respiratory Medicine – Adult Asthma Outcomes and Management
  • NITI Aayog – Air Pollution and Respiratory Health Reports
  • Statista – Global Asthma Prevalence and Trends

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