• Published on: Jul 22, 2020
  • 2 minute read
  • By: Dr Rajan Choudhary

The Oxford Vaccine

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Recently we wrote a blog on the success of an RNA vaccine against SARS-CoV-2, the virus responsible for COVID-19. Within just a few weeks of that incredible research breakthrough, researchers at Oxford University’s Jenner Institute have announced a COVID vaccine that has induced remarkable immune response against the virus.

This study was published in the Lancet, one of the most prestigious medical journals in the world, and a simple summary suggests the vaccine has no early safety concern and is able to induce a strong immune response with both T cells and B cell/antibodies.

THE VACCINE

ChAdOx1 nCoV-19, now known as AZD1222, was co-developed by the University of Oxford and one of its spin-off companies, Vaccitech. The vaccine uses a viral vector based on a common cold virus (adenovirus). This carries genetic material for the SARS-CoV-2 spike protein. In our previous blog, we saw how the spike proteins are used by the virus to target and fuse with our target cells, allowing the virus to invade, replicate and ultimately cause the disease known as COVID. It is also a good target for the human immune system to recognize and attack.

The viral vector delivers the genetic material inside our cells. The spike protein is then produced by our cells, recognized by the immune system as a viral target, and an immune response is created against it. This can be antibodies, which recognize, attach to and mark the virus in our blood, allowing for other white blood cells to destroy the virus.

In this case, the vaccine also produced a T cell response. T cells can recognize cells infected by a virus-based on the markers present on the surface of infected cells. They can tell an infected cell to destroy itself, thereby destroying the virus within without spreading the infection. They also have other functions that we will not discuss in this blog.

THE STUDY

This study was a Phase I/II trial that started in April using the vaccine named ChAdOx1 nCoV-19. This vaccine development started in January 2020, and progress on development has been incredibly rapid. Whilst our previous study had just 45 people, this study looked reviewed over 1,000 healthy adults. 10 of these participants received two doses of the vaccine.

In a study the more participants there are, the greater the power of the study. If the vaccine has any side effects, even ones that rarely occur, it is more likely to be picked up in studies with more people. Similarly having more people helps show that the vaccine is effective, and the strong responses are not merely a fluke or accident. Another benefit of this study is it was able to compare the vaccine against a control group. This shows the results were not simply a placebo and allowed comparison of side effects as well.

The majority of side effects were feeling feverish, chills, muscle ache, headache, and malaise, all symptoms treatable with paracetamol. None of the participants had any serious side effects. It took just 14 days to create a T cell response, and  28 days to make strong antibodies. In 91% of patients, this was enough to neutralize the COVID coronavirus. Receiving two doses gave an even stronger antibody response, and all participants were able to stop the virus.

 

WHAT NEXT

The news from the University of Oxford is needed, as infection rate and mortality continue to increase in countries such as the US and Brazil. The ability to induce an antibody response without causing harm to the patient shows we have made huge progress in the fight against COVID-19. Further Large scale Phase III trials been set up through a global partnership, and include studies in the US with over 30,000 patients, studies in children as well as some in low to middle-income countries.

If successful a vaccine would be essential in preventing a second wave of COVID in the winter when the elderly population is most at risk. And it would be the key to restarting the economy and getting our everyday lives back to where it was pre-pandemic.

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Virtual Clinic India: How SecondMedic Is Transforming Digital Healthcare

Virtual Clinic India: How SecondMedic Is Transforming Digital Healthcare

Healthcare in India is undergoing a significant transformation as digital platforms reshape how people access medical care. Virtual clinics have emerged as a powerful solution, offering patients immediate access to doctors, diagnostics, prescriptions, and continuous monitoring—without the need for physical hospital visits. This model has become increasingly important in a country where population density, geographical barriers, and long wait times often make healthcare inaccessible or inconvenient.

A virtual clinic uses telemedicine, digital records, online diagnostics, AI tools, and remote monitoring to offer a full healthcare experience through smartphones or computers. SecondMedic is among the leaders in this space, providing a robust virtual clinic ecosystem designed to support preventive health, chronic disease management, and immediate care for everyday medical needs.

The Role of Virtual Clinics in India’s Healthcare Evolution

India faces significant challenges including uneven specialist distribution, crowded hospitals, and rising lifestyle diseases. Virtual clinics bridge these gaps by making healthcare more accessible, affordable, and continuous. They enable patients from metropolitan areas, rural communities, and even remote regions to receive quality care without leaving home.

Key drivers behind virtual clinic growth include:

  • Growing smartphone and internet penetration

  • Increased comfort with digital health platforms

  • The need for safe and convenient care

  • Rising chronic illnesses requiring ongoing monitoring

  • Awareness of preventive healthcare
     

As a result, virtual clinics are becoming the first point of contact for many health concerns.

How Virtual Clinics Deliver Complete Healthcare

Virtual clinics are more than video consultations. They integrate multiple components of healthcare into a unified digital experience. SecondMedic’s virtual clinic model ensures continuity of care by bringing together doctors, diagnostics, monitoring tools, pharmacy support, and digital health records.

Core pillars of virtual clinic care include:

  • Instant doctor access

  • Seamless diagnostic testing

  • AI-based symptom evaluation

  • E-prescriptions

  • Medication delivery

  • Chronic disease monitoring

  • Preventive health programs
     

This creates an end-to-end flow that mirrors the experience of visiting a physical clinic, but with added convenience and personalization.

Online Consultations: Immediate Access to Specialists

One of the strongest features of a virtual clinic is the ability to consult qualified doctors quickly. Instead of waiting days for appointments or traveling long distances, patients can connect with specialists through secure video calls or chat.

Virtual consultations are especially useful for:

  • Common illnesses

  • Follow-up appointments

  • Second opinions

  • Chronic condition management

  • Mental health support

  • Elderly care

  • Pediatric queries
     

SecondMedic ensures that all consultations are supported by electronic health records, making the experience seamless and informed.

Digital Diagnostics and At-Home Lab Testing

Diagnostics are a core component of healthcare, and virtual clinics have made them significantly more accessible. Users can book lab tests online and have samples collected from their home. Results are delivered digitally, enabling faster diagnosis and treatment.

Advantages of digital diagnostics include:

  • No travel or waiting lines

  • Fast report turnaround

  • Integration with doctor consultations

  • Easy follow-up and comparisons over time

  • Better compliance for chronic disease tracking
     

SecondMedic partners with certified diagnostic labs to ensure high-quality test processing and accurate digital reporting.

Remote Monitoring and Chronic Disease Care

Chronic diseases such as diabetes, hypertension, heart illness, and thyroid disorders require ongoing monitoring. Virtual clinics use connected devices and AI-driven alerts to help patients stay on track with their health goals.

Common remote monitoring tools include:

  • Glucometers

  • Blood pressure monitors

  • Heart-rate trackers

  • Pulse oximeters

  • Weight and BMI tools

  • Sleep monitors

  • Wearable sensors
     

SecondMedic uses advanced analytics to detect risk patterns early, send reminders, and support long-term condition management.

E-Prescriptions and Digital Pharmacy Support

Virtual clinics simplify the process of receiving medical prescriptions and ordering medicines. E-prescriptions are accurate, tamper-proof, and instantly shareable with online pharmacies.

Digital pharmacy support helps with:

  • Medication delivery

  • Monthly chronic care refills

  • Transparent drug information

  • Avoiding prescription errors

  • Improving medication adherence
     

SecondMedic integrates e-prescriptions directly with its pharmacy partners, making the treatment process seamless.

Preventive Healthcare Through Virtual Clinics

Preventive care is becoming a priority for many Indians due to rising lifestyle diseases and increasing awareness of early screening. Virtual clinics support this need through personalized health plans designed using AI assessments, digital screenings, and doctor insights.

Preventive healthcare offerings include:

  • Annual full-body checkups

  • Lifestyle assessments

  • Diet and fitness plans

  • Stress and sleep guidance

  • Vaccination reminders

  • Long-term wellness tracking
     

SecondMedic’s preventive programs are designed to detect risks early and help users adopt healthier habits.

How Virtual Clinics Improve Healthcare Accessibility in India

Virtual clinics remove geographical barriers by bringing medical care to people who otherwise face difficulty accessing doctors. This includes:

  • Rural regions with limited healthcare facilities

  • Urban areas with long hospital wait times

  • Elderly individuals who cannot travel easily

  • Busy professionals needing flexible care

  • Patients seeking discretion for sensitive concerns
     

With increased digital literacy and affordable smartphones, virtual clinics are becoming accessible to a wide demographic.

The Future of Virtual Clinics in India

The future of virtual clinics is strong, supported by national initiatives like the Ayushman Bharat Digital Mission (ABDM), which encourages digital health adoption. AI-driven diagnostics, intelligent triaging, predictive health tools, and integrated hospital systems will further strengthen the virtual care model.

Upcoming trends include:

  • AI chat-based symptom evaluation

  • Virtual reality rehabilitation sessions

  • Smart device-linked monitoring

  • AI-based early disease detection

  • Comprehensive preventive health ecosystems

  • Hybrid care combining virtual and in-clinic visits
     

SecondMedic is actively developing next-generation virtual clinic technologies to make healthcare more proactive and patient-centered.

Conclusion

Virtual clinics are revolutionizing healthcare delivery in India by offering convenient, reliable, and digitally connected care. They bring together consultations, diagnostics, monitoring, and preventive health in one platform, reducing barriers and enabling patients to receive high-quality medical support anytime, anywhere. SecondMedic leads this transformation with a comprehensive virtual clinic model designed to support long-term health and wellbeing.

To access virtual consultations, digital diagnostics, and remote care services, visit www.secondmedic.com

References

  1. NITI Aayog - Telemedicine and Digital Health Report 2024

  2. Statista - Telehealth Usage India 2025

  3. WHO - Digital Health Standards

  4. IMARC - India Telemedicine Market Forecast

  5. ABDM - Ayushman Bharat Digital Health Guidelines

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