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Published on: Jul 22, 2020
2 minute read
By: Dr Rajan Choudhary

The Oxford Vaccine

Recently we wrote a blog on the success of an RNA vaccine against SARS-CoV-2, the virus responsible for COVID-19. Within just a few weeks of that incredible research breakthrough, researchers at Oxford University’s Jenner Institute have announced a COVID vaccine that has induced remarkable immune response against the virus.

This study was published in the Lancet, one of the most prestigious medical journals in the world, and a simple summary suggests the vaccine has no early safety concern and is able to induce a strong immune response with both T cells and B cell/antibodies.

THE VACCINE

ChAdOx1 nCoV-19, now known as AZD1222, was co-developed by the University of Oxford and one of its spin-off companies, Vaccitech. The vaccine uses a viral vector based on a common cold virus (adenovirus). This carries genetic material for the SARS-CoV-2 spike protein. In our previous blog, we saw how the spike proteins are used by the virus to target and fuse with our target cells, allowing the virus to invade, replicate and ultimately cause the disease known as COVID. It is also a good target for the human immune system to recognize and attack.

The viral vector delivers the genetic material inside our cells. The spike protein is then produced by our cells, recognized by the immune system as a viral target, and an immune response is created against it. This can be antibodies, which recognize, attach to and mark the virus in our blood, allowing for other white blood cells to destroy the virus.

In this case, the vaccine also produced a T cell response. T cells can recognize cells infected by a virus-based on the markers present on the surface of infected cells. They can tell an infected cell to destroy itself, thereby destroying the virus within without spreading the infection. They also have other functions that we will not discuss in this blog.

THE STUDY

This study was a Phase I/II trial that started in April using the vaccine named ChAdOx1 nCoV-19. This vaccine development started in January 2020, and progress on development has been incredibly rapid. Whilst our previous study had just 45 people, this study looked reviewed over 1,000 healthy adults. 10 of these participants received two doses of the vaccine.

In a study the more participants there are, the greater the power of the study. If the vaccine has any side effects, even ones that rarely occur, it is more likely to be picked up in studies with more people. Similarly having more people helps show that the vaccine is effective, and the strong responses are not merely a fluke or accident. Another benefit of this study is it was able to compare the vaccine against a control group. This shows the results were not simply a placebo and allowed comparison of side effects as well.

The majority of side effects were feeling feverish, chills, muscle ache, headache, and malaise, all symptoms treatable with paracetamol. None of the participants had any serious side effects. It took just 14 days to create a T cell response, and 28 days to make strong antibodies. In 91% of patients, this was enough to neutralize the COVID coronavirus. Receiving two doses gave an even stronger antibody response, and all participants were able to stop the virus.

WHAT NEXT

The news from the University of Oxford is needed, as infection rate and mortality continue to increase in countries such as the US and Brazil. The ability to induce an antibody response without causing harm to the patient shows we have made huge progress in the fight against COVID-19. Further Large scale Phase III trials been set up through a global partnership, and include studies in the US with over 30,000 patients, studies in children as well as some in low to middle-income countries.

If successful a vaccine would be essential in preventing a second wave of COVID in the winter when the elderly population is most at risk. And it would be the key to restarting the economy and getting our everyday lives back to where it was pre-pandemic.

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Monthly Field Day with Patients & Staff: Building Trust, Engagement, and Wellbeing

Healthcare is built on relationships. While diagnosis, treatment and technology are critical, the human connection between patients and healthcare staff remains central to healing and recovery. A Monthly Field Day with Patients & Staff is a thoughtful initiative designed to strengthen these relationships by creating opportunities for interaction outside routine clinical environments.

In today’s healthcare systems, patient engagement and staff wellbeing are recognised as essential components of quality care. Monthly field days provide a structured yet informal platform to support both.

What Is a Monthly Field Day with Patients & Staff?

A Monthly Field Day is a planned engagement event where patients and healthcare staff come together to participate in non-clinical activities. These events focus on:

interaction
wellbeing
communication
community-building

They are not medical appointments but shared experiences that promote trust and understanding.

Why Field Days Matter in Healthcare

Healthcare Is Emotionally Demanding

Patients often experience anxiety, fear and uncertainty. Staff face long hours, emotional stress and high responsibility. Field days offer a space for:

relaxed interaction
emotional connection
mutual understanding

This humanises care delivery.

Strengthening Patient–Staff Trust

Trust grows through:

open communication
shared experiences
consistent engagement

Field days reduce perceived barriers between patients and healthcare teams.

Benefits for Patients

Improved Comfort and Confidence

Patients feel more at ease when they know the people involved in their care beyond clinical roles.

Better Engagement in Care

Engaged patients are more likely to:

ask questions
follow care plans
attend follow-ups

This leads to improved health outcomes.

Emotional and Social Wellbeing

Social interaction, light activity and positive experiences support mental and emotional health, especially for patients with chronic conditions.

Benefits for Healthcare Staff

Reduced Burnout

Regular non-clinical engagement helps:

reduce emotional fatigue
restore motivation
improve job satisfaction

Stronger Team Relationships

Shared activities strengthen teamwork and communication among staff members.

Renewed Sense of Purpose

Seeing patients outside stressful clinical settings reinforces the meaningful impact of healthcare work.

Organisational Benefits

Enhanced Patient-Centered Culture

Field days reinforce values of empathy, accessibility and respect.

Improved Patient Satisfaction

Trust and familiarity contribute to better patient experiences and feedback.

Better Communication and Feedback

Informal settings encourage honest dialogue, helping organisations understand patient needs and expectations.

Activities Commonly Included in Field Days

Wellness Activities

gentle exercises
stretching or yoga
breathing sessions

Educational Interactions

health awareness talks
preventive care discussions
lifestyle guidance

Recreational and Social Activities

group games
creative sessions
interactive challenges

These activities promote joy, connection and inclusion.

Inclusivity and Accessibility

Effective field days are:

inclusive of different age groups
adaptable for physical limitations
culturally sensitive
welcoming and non-competitive

Inclusivity ensures meaningful participation for all.

Why Monthly Frequency Works Best

Monthly scheduling:

maintains continuity
builds long-term trust
prevents disengagement
supports gradual relationship building

Consistency transforms engagement into culture.

Evidence Supporting Engagement Initiatives

Research shows that:

patient engagement improves health outcomes
staff wellbeing reduces errors and burnout
relationship-based care enhances satisfaction

Global health frameworks emphasise people-centred care models.

Measuring the Impact of Field Days

Impact can be evaluated through:

patient feedback
staff engagement surveys
participation rates
qualitative testimonials

Regular assessment helps refine the program.

Implementing a Successful Monthly Field Day

Key elements include:

leadership support
clear objectives
simple, inclusive activities
consistent scheduling
feedback-driven improvement

Success depends on commitment rather than scale.

Long-Term Impact on Healthcare Culture

Over time, Monthly Field Days contribute to:

stronger trust
improved communication
better morale
enhanced care experience

They reinforce the idea that healthcare is a partnership between people.

Conclusion

A Monthly Field Day with Patients & Staff is more than an engagement activity—it is a meaningful investment in trust, wellbeing and human connection. By creating shared experiences beyond clinical settings, healthcare organisations strengthen relationships that directly influence care quality and satisfaction. In an environment often driven by efficiency and outcomes, monthly field days remind us that compassion, communication and community remain at the heart of effective healthcare.

References

World Health Organization (WHO) – People-Centred Care and Patient Engagement
Indian Council of Medical Research (ICMR) – Patient Experience and Care Quality Studie
Lancet – Patient–Provider Relationships and Health Outcomes
National Health Systems Resource Centre – Community Engagement in Healthcare
Indian Journal of Healthcare Management – Staff Wellbeing and Patient Satisfaction
Statista – Healthcare Engagement and Experience Trends

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