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Published on: Jul 22, 2020
2 minute read
By: Dr Rajan Choudhary

The Oxford Vaccine

Recently we wrote a blog on the success of an RNA vaccine against SARS-CoV-2, the virus responsible for COVID-19. Within just a few weeks of that incredible research breakthrough, researchers at Oxford University’s Jenner Institute have announced a COVID vaccine that has induced remarkable immune response against the virus.

This study was published in the Lancet, one of the most prestigious medical journals in the world, and a simple summary suggests the vaccine has no early safety concern and is able to induce a strong immune response with both T cells and B cell/antibodies.

THE VACCINE

ChAdOx1 nCoV-19, now known as AZD1222, was co-developed by the University of Oxford and one of its spin-off companies, Vaccitech. The vaccine uses a viral vector based on a common cold virus (adenovirus). This carries genetic material for the SARS-CoV-2 spike protein. In our previous blog, we saw how the spike proteins are used by the virus to target and fuse with our target cells, allowing the virus to invade, replicate and ultimately cause the disease known as COVID. It is also a good target for the human immune system to recognize and attack.

The viral vector delivers the genetic material inside our cells. The spike protein is then produced by our cells, recognized by the immune system as a viral target, and an immune response is created against it. This can be antibodies, which recognize, attach to and mark the virus in our blood, allowing for other white blood cells to destroy the virus.

In this case, the vaccine also produced a T cell response. T cells can recognize cells infected by a virus-based on the markers present on the surface of infected cells. They can tell an infected cell to destroy itself, thereby destroying the virus within without spreading the infection. They also have other functions that we will not discuss in this blog.

THE STUDY

This study was a Phase I/II trial that started in April using the vaccine named ChAdOx1 nCoV-19. This vaccine development started in January 2020, and progress on development has been incredibly rapid. Whilst our previous study had just 45 people, this study looked reviewed over 1,000 healthy adults. 10 of these participants received two doses of the vaccine.

In a study the more participants there are, the greater the power of the study. If the vaccine has any side effects, even ones that rarely occur, it is more likely to be picked up in studies with more people. Similarly having more people helps show that the vaccine is effective, and the strong responses are not merely a fluke or accident. Another benefit of this study is it was able to compare the vaccine against a control group. This shows the results were not simply a placebo and allowed comparison of side effects as well.

The majority of side effects were feeling feverish, chills, muscle ache, headache, and malaise, all symptoms treatable with paracetamol. None of the participants had any serious side effects. It took just 14 days to create a T cell response, and 28 days to make strong antibodies. In 91% of patients, this was enough to neutralize the COVID coronavirus. Receiving two doses gave an even stronger antibody response, and all participants were able to stop the virus.

WHAT NEXT

The news from the University of Oxford is needed, as infection rate and mortality continue to increase in countries such as the US and Brazil. The ability to induce an antibody response without causing harm to the patient shows we have made huge progress in the fight against COVID-19. Further Large scale Phase III trials been set up through a global partnership, and include studies in the US with over 30,000 patients, studies in children as well as some in low to middle-income countries.

If successful a vaccine would be essential in preventing a second wave of COVID in the winter when the elderly population is most at risk. And it would be the key to restarting the economy and getting our everyday lives back to where it was pre-pandemic.

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Monthly Field Day with Patients & Staff: Building Stronger Connections for Better Health

Healthcare outcomes are shaped not only by medical treatments but also by trust, communication and community engagement. As healthcare systems in India move toward preventive and patient-centric models, initiatives that foster meaningful interaction between patients and healthcare professionals are gaining importance. One such initiative is the Monthly Field Day with Patients & Staff.

A field day creates a shared space where patients and healthcare teams interact beyond clinical settings. These interactions humanise healthcare, improve understanding and encourage long-term wellness practices.

Why Community Engagement Matters in Healthcare

Modern healthcare recognises that health is influenced by behaviour, awareness and social support. According to the World Health Organization (WHO) and NITI Aayog, community-based health engagement improves preventive care adoption and patient outcomes.

Field days help bridge the gap between healthcare providers and patients by:

encouraging open dialogue
reducing fear and hesitation
promoting shared responsibility for health

What Is a Monthly Field Day with Patients & Staff?

A Monthly Field Day with Patients & Staff is a structured wellness initiative organised outside the routine clinical environment. It focuses on interaction, education and preventive health activities.

Typical elements include:

basic health screenings
lifestyle education sessions
fitness or relaxation activities
informal conversations with healthcare staff
family and caregiver participation

The aim is to create a supportive and approachable healthcare experience.

Why Monthly Frequency Matters

Consistency is key in behaviour change and preventive health.

Monthly field days:

reinforce health messages regularly
build familiarity and trust
allow continuous follow-up
keep wellness top of mind

According to public health studies, repeated engagement significantly improves health literacy and adherence.

Benefits for Patients

1. Improved Health Awareness

Patients gain better understanding of:

chronic disease management
preventive screenings
nutrition and lifestyle habits

Education in informal settings improves retention.

2. Increased Comfort with Healthcare Teams

Regular interaction reduces anxiety and hesitation around seeking medical care.

Patients are more likely to:

ask questions
follow medical advice
attend follow-ups

3. Early Risk Identification

Field days often include basic screenings that help detect:

high blood pressure
elevated blood sugar
obesity risk

Early identification enables timely intervention.

4. Enhanced Emotional Wellbeing

Social interaction and community activities reduce feelings of isolation, especially among elderly or chronically ill patients.

Benefits for Healthcare Staff

1. Better Understanding of Patient Needs

Direct interaction outside clinical settings helps staff understand patient challenges more holistically.

2. Improved Communication Skills

Informal engagement strengthens empathy and communication effectiveness.

3. Reduced Burnout

Positive patient interaction and community appreciation contribute to staff morale and job satisfaction.

WHO recognises staff wellbeing as a critical factor in healthcare quality.

Role of Field Days in Preventive Healthcare

Preventive healthcare focuses on reducing disease burden before complications arise. Field days support prevention by:

promoting routine screenings
encouraging healthy lifestyle habits
addressing myths and misconceptions
reinforcing long-term care plans

NITI Aayog identifies community engagement as a cornerstone of preventive healthcare strategies.

Activities Commonly Included in Field Days

Health Screening Stations

Blood pressure, blood sugar, BMI and basic assessments.

Wellness Education

Short talks on nutrition, exercise, sleep and stress.

Interactive Sessions

Q&A discussions with doctors, nurses and health educators.

Physical Activities

Group walks, yoga sessions or light exercises.

Family Engagement

Including caregivers improves adherence and support systems.

Impact on Chronic Disease Management

For patients with chronic conditions such as diabetes or hypertension, regular engagement:

improves medication adherence
reinforces lifestyle modification
reduces emergency visits

Lancet studies highlight that community-based interventions improve chronic disease outcomes.

Building Trust Through Transparency

Field days foster trust by:

making healthcare providers approachable
encouraging open dialogue
demonstrating commitment to patient wellbeing

Trust improves treatment adherence and satisfaction.

Role of Data and Feedback

Feedback collected during field days helps healthcare organisations:

identify common concerns
refine wellness programs
personalise future interventions

Data-driven engagement enhances program effectiveness.

Long-Term Impact on Healthcare Outcomes

Organisations that invest in regular patient-staff engagement observe:

higher patient satisfaction
improved preventive screening rates
reduced disease complications
stronger community relationships

According to WHO, patient-centred care models improve health outcomes and system efficiency.

Why Field Days Are Especially Relevant in India

India’s diverse population faces challenges such as:

limited health literacy
delayed care-seeking
chronic disease burden

Community-based initiatives like field days address these challenges through education and trust-building.

Conclusion

A Monthly Field Day with Patients & Staff is more than a community event—it is a strategic preventive healthcare initiative. By fostering open communication, promoting health awareness and strengthening relationships, field days improve patient engagement and staff wellbeing alike. In a healthcare landscape increasingly focused on prevention and community trust, regular field days play a vital role in building healthier, more connected communities.

References

ICMR – Community Health and Preventive Care Reports
National Family Health Survey (NFHS-5) – Health Awareness and Engagement Dat
NITI Aayog – Community-Based Preventive Healthcare Strategies
WHO – Patient-Centred Care and Community Health Guidelines
Lancet – Community Engagement and Health Outcome Studies
Statista – Healthcare Engagement and Preventive Care Trends India
EY-FICCI – Healthcare Workforce and Patient Engagement Reports

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