• Published on: Apr 04, 2020
  • 2 minute read
  • By: Dr Rajan Choudhary

THE CHALLENGES FACED IN MAKING A VACCINE FOR COVID-19 — Part 2

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Previously we’ve seen the difficulties researches face in trying to make a vaccine. But even if we make a vaccine, that’s just half the battle. Viruses are unique because they can mutate, and they can mutate to astonishing degrees. In humans mutations to tiny parts of our DNA can cause severe diseases or even death. In viruses mutations can change their structure, making them more infective and giving them a new coat. It gives them a survival advantage, the ability to evade our immune system and make our vaccines ineffective. This is why we need a new flu vaccine every year.

If it takes months to a year to develop a vaccine, it will be based off the virus found in December 2019. By this time the virus may have spread and mutated to such a degree that it is not effective. This does not mean all the effort was for nothing. Going through the steps and understanding the issues faced with making a COVID-19 vaccine can make the process quicker for subsequent vaccines against its mutated versions.

https://www.sciencealert.com/who-says-a-coronavirus-vaccine-is-18-months-away So Long to Develop a Vaccine

FAILURES FROM THE PAST

These issues were faced during the Ebola and Zika virus epidemics, and many large companies are understandably hesitant to develop vaccines for COVID-19. Ebola first broke out in 2014, and it was only in December 2019 that the first vaccine was approved for use by the European Commission and the United States. This is despite multiple large institutes in Canada and the UK working together to develop it.

13 different Ebola vaccine candidates had been identified soon after the outbreak, but none had been tested on humans. Unfortunately this is the most expensive part of development, and the area biopharmecuticals stand to loose the most money. Return on investments is also low, since epidemics usually take place in poorer countries, and the potential customers are unable to pay the high prices for these brand new treatments. It is an unfortunate realisation that research into medicines is driven by rich countries, for diseases that affect the rich.

https://newint.org/features/web-exclusive/2016/06/16/why-did-the-market-fail-to-produce-an-ebola-vaccine Ebola 

WHERE ARE WE NOW?

This is all well and good, but what does it mean for COVID-19? We know we cannot rush a vaccine, because a poorly designed vaccine with unknown side effects can cause more harm than good, especially if given to children or the elderly. Currently the WHO are tracking 31 different attempts at making a COVID-19 vaccine, using different methods as discussed before. All of these are currently in the pre-clinical stage, focusing on isolating parts of the virus and creating a target the body will recognise and react to.

Researchers at the University of Queensland were one of the first to start using the genetic code of COVID-19, released openly by Chinese researchers. They have developed a test vaccine within 6 weeks using state-of-the-art genetic techniques, used for the first time. If animal models prove successful then human testing might begin within 6 months. In the pharmaceutical industry advancements this quick are almost unheard of.

Additionally over 293 clinical trials are taking place in China using existing drugs on the market. The advantage is we already know these drugs are safe to use in humans, but we are trying to work out if they will work against COVID-19. Some scientists are also looking at medications that were initially developed against SARS and MERS, but never completed because these outbreaks died down and the medication was no longer required.

https://www.aljazeera.com/news/2020/03/china-recovered-develop-effective-covid-19-treatments-200302082850237.html COVID-19 treatments

https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus-landscape-ncov.pdf?ua=1 WHO news

https://www.theverge.com/2020/2/28/21156385/covid-coronavirus-vaccine-treatment-moderna-remdesivir-research COVID-19 treatment

Its not all doom and gloom. Challenges drive innovation, and we are already benefitting from this. New forms of genetic sequencing, new methods for extracting viral proteins, new techniques in creating a vaccine. These innovations are already benefitting us on the drive to create an effective vaccine for COVID-19, and they will benefit us in the future when the next pandemic hits.

Dr Rajan Choudhary, Product Manager Second Medic UK

www.secondmedic.com

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Remote Cardiac Monitoring India: Transforming Heart Health Through Continuous Digital Tracking

Remote Cardiac Monitoring India: Transforming Heart Health Through Continuous Digital Tracking

Heart disease remains one of the leading causes of death in India. According to the Indian Council of Medical Research (ICMR), cardiovascular diseases account for nearly 28% of total deaths in the country. With rising stress levels, sedentary lifestyles, air pollution exposure, diabetes, hypertension, and delayed diagnosis, the need for better cardiac monitoring has grown significantly. Remote cardiac monitoring India is emerging as a powerful solution to monitor heart health in real time and detect abnormalities before they turn into emergencies.

Remote cardiac monitoring involves wearable or portable ECG devices that track heart signals continuously or at regular intervals. These devices transmit data securely to cardiologists or AI-based systems, enabling early detection of arrhythmias, rhythm abnormalities, ischemic patterns, and fluctuations in heart rate variability (HRV). SecondMedic brings cutting-edge remote monitoring options that help patients manage heart-related risks effectively, anytime and anywhere.

Why Remote Cardiac Monitoring Is Becoming Essential in India

India has a disproportionately high cardiac burden. Reports by WHO show that Indians suffer heart attacks at a younger age compared to global averages. Additionally, more than 50% of cardiac patients in India do not recognize early warning signs and reach hospitals late.

Remote cardiac monitoring helps solve these challenges by offering:

  • Early arrhythmia detection
     

  • Timely identification of heart stress
     

  • Post-surgery cardiac recovery supervision
     

  • Reduced hospital dependency
     

  • Continuous heart rhythm tracking
     

  • Better outcomes for chronic heart patients
     

With easy access to digital ECG devices, monitoring is no longer limited to hospitals.

How Remote Cardiac Monitoring Works

Remote cardiac monitoring uses smart ECG patches, chest straps, handheld ECG devices, and even AI-driven wearables. These devices record heart electrical activity or rhythm patterns and transmit the data to:

  • Cardiologists
     

  • Digital dashboards
     

  • AI algorithms
     

  • Care teams
     

The real-time nature of the data allows immediate response in case of abnormalities.

Core parameters captured include:

  • ECG waveform
     

  • Heart rate variability (HRV)
     

  • Arrhythmias (AFib, SVT, PVCs)
     

  • Tachycardia or bradycardia
     

  • QT interval abnormalities
     

  • Stress-related heart rhythm changes
     

SecondMedic ensures that the captured data is clinically relevant and accessible to both patients and doctors.

Patients Who Benefit Most from Remote Cardiac Monitoring

1. Post-Cardiac Surgery Patients

After angioplasty, bypass surgery, pacemaker implantation, or stent placement, patients require strict monitoring for weeks or months. Remote devices track recovery trends.

2. Individuals With Arrhythmia

Conditions like atrial fibrillation (AFib) require continuous monitoring, as episodes may come and go unpredictably.

3. Patients With Heart Failure

Monitoring helps evaluate worsening symptoms or cardiac stress.

4. High-Risk Individuals

Patients with diabetes, hypertension, obesity, or family history of heart disease benefit from early detection.

5. Elderly and Homebound Patients

Remote monitoring eliminates frequent hospital visits for routine ECG checks.

6. People Experiencing Palpitations

Intermittent symptoms can be captured and analyzed with wearable monitors.

Key Advantages of Remote Cardiac Monitoring

Early Detection Saves Lives

Abnormal rhythms such as atrial fibrillation can go unnoticed and lead to stroke. Remote monitoring detects these in real time.

Avoids Emergency Situations

AI alerts allow doctors to intervene early before symptoms worsen.

Better Long-Term Cardiac Care

Continuous data provides better insights than occasional clinic-based ECGs.

High Accuracy

Medical-grade ECG wearables match hospital-level precision for diagnosis.

Patient Convenience

Patients can monitor their heart health from home, office, or while traveling.

Improved Doctor Decisions

Trend-based cardiac data supports more accurate treatment planning.

Role of AI in Remote Cardiac Monitoring

AI and machine learning models analyze patterns collected from ECG devices.

AI enhances care by:

  • Identifying subtle abnormalities
     

  • Predicting arrhythmia events
     

  • Detecting ischemic trends early
     

  • Classifying ECG signal types
     

  • Reducing manual interpretation burden
     

SecondMedic integrates AI-assisted analysis to strengthen cardiac risk evaluation.

Post-Surgery and Rehabilitation Monitoring

Cardiac rehabilitation is crucial after major procedures. Remote monitoring provides:

  • Heart rate control
     

  • Blood pressure trend tracking
     

  • Rhythm abnormality detection
     

  • Activity monitoring
     

  • Medication adherence support
     

This reduces readmission rates and supports safer recovery.

Remote Cardiac Monitoring in Rural India

Many small towns lack cardiology specialists or advanced ECG equipment. Remote monitoring bridges this gap by:

  • Connecting patients to cardiologists virtually
     

  • Providing ECG analysis without hospital visits
     

  • Reducing delay in diagnosis
     

  • Supporting long-term monitoring at home
     

SecondMedic helps democratize heart care access across India.

Challenges and Solutions

Device Accuracy Variability

Solution: Use medical-grade, certified ECG wearables.

Digital Literacy Issues

Solution: Simple interfaces, guided onboarding, multilingual instructions.

Data Security

Solution: End-to-end encrypted data under DPDP Act compliance.

Connectivity Challenges

Solution: Devices with offline sync capabilities.

Future of Remote Cardiac Monitoring in India

The next decade will bring significant advancements:

  • Patch-based continuous ECG devices
     

  • AI-driven early warning scores
     

  • Smart pacemaker data integration
     

  • Multi-day continuous ECG monitoring
     

  • Predictive arrhythmia detection algorithms
     

  • Tele-ICU support for remote patients
     

SecondMedic is actively working to integrate next-generation cardiac monitoring tools into its platform.

Conclusion

Remote cardiac monitoring India is transforming heart care by enabling real-time ECG tracking, early abnormality detection, and continuous cardiologist oversight. This digital-first approach empowers high-risk patients, improves outcomes, and ensures safer long-term cardiac management. SecondMedic’s integrated digital heart monitoring solutions allow patients across India to access expert cardiac care anytime.

To explore remote cardiac monitoring solutions, visit www.secondmedic.com

 

References

  • ICMR - Cardiovascular disease burden
     

  • WHO - Early cardiac risk detection
     

  • NITI Aayog - Digital health innovation in India
     

  • ABDM - Unified digital health mission
     

  • Statista - Wearable and ECG device adoption India
     

  • SecondMedic cardiac care insights

See all

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