• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Gastrointestinal Infections in Humid Weather

Gastrointestinal Infections in Humid Weather: Causes, Symptoms, and Prevention

Introduction

With the arrival of the rainy season and rising humidity levels, there’s a sudden spike in health issues—especially those related to the stomach. One of the most common problems during this time is gastrointestinal infections in humid weather. From children to adults, no one is completely safe when it comes to these infections. They may lead to discomfort, dehydration, and even hospitalization if not managed early.

This blog covers the key causes, symptoms, and effective prevention methods for gastrointestinal infections during humid months in India.

 

Why Humid Weather Triggers Gastrointestinal Infections

Humidity creates the perfect breeding ground for bacteria, viruses, and parasites. The combination of moisture and heat increases the risk of food and water contamination. Here’s why gastrointestinal infections are common during this time:

  • Bacterial Growth: Warm and moist conditions allow bacteria like E. coli, Salmonella, and Shigella to multiply faster.
     

  • Contaminated Water: Heavy rains can mix sewage with drinking water supplies, increasing the chances of infection.
     

  • Improper Food Storage: Heat and moisture spoil food quickly, making it a carrier of infections.
     

  • Street Food Consumption: Monsoon cravings often lead people to consume unhygienic street food, increasing the infection risk.
     

 

Common Gastrointestinal Infections in Humid Weather

Some of the most frequently reported infections during humid conditions include:

1. Bacterial Diarrhea

Caused by E. coli, Salmonella, or Campylobacter, this infection results in watery stools, abdominal cramps, and fever.

2. Cholera

Triggered by Vibrio cholerae, cholera spreads through contaminated water and causes severe watery diarrhea and dehydration.

3. Typhoid Fever

Caused by Salmonella typhi, this infection spreads via contaminated food or water and brings symptoms like fever, weakness, and abdominal pain.

4. Hepatitis A & E

These viral infections spread through contaminated water and affect the liver, leading to symptoms like jaundice, nausea, and fatigue.

5. Amoebiasis and Giardiasis

These are parasitic infections often found in contaminated drinking water and cause prolonged diarrhea and stomach pain.

 

Symptoms to Watch Out For

It’s crucial to identify the symptoms early to avoid complications. Look out for:

  • Persistent or watery diarrhea

  • Vomiting and nausea

  • Abdominal cramps or pain

  • Fever and chills

  • Loss of appetite

  • Dehydration (dry mouth, low urine output, weakness)

  • Jaundice (yellowing of eyes and skin in hepatitis)
     

If any of these symptoms last more than 2 days or worsen, consult a doctor immediately.

 

Who Is Most at Risk?

Some groups are more vulnerable to gastrointestinal infections in humid weather, including:

  • Children under 5 years

  • Elderly adults

  • Pregnant women

  • People with weakened immunity or chronic illnesses

  • Individuals living in flood-prone or poorly sanitized areas
     

 

Prevention Tips: How to Stay Safe

You can significantly reduce your chances of falling sick by following these simple preventive measures:

1. Drink Safe Water

  • Always boil drinking water or use water purifiers.

  • Avoid drinking outside water, especially from open sources or street vendors.
     

2. Eat Fresh, Home-Cooked Food

  • Avoid street food and uncovered items.

  • Consume freshly prepared meals and store leftovers properly in the refrigerator.
     

3. Maintain Hand Hygiene

  • Wash hands thoroughly with soap before eating or cooking.

  • Use a hand sanitizer when soap isn’t available.
     

4. Wash Fruits and Vegetables

  • Clean all produce with clean water.

  • Soak leafy greens in salt water before cooking or eating.
     

5. Be Cautious While Traveling

  • Carry your own drinking water and snacks.

  • Avoid uncooked or cold food items from unknown sources.
     

 

Tests You Can Consider (Powered by Thyrocare at SecondMedic)

If symptoms persist or you want to rule out infections, consider the following lab tests:

  • Stool Routine & Microscopy Test

  • Widal Test (for Typhoid)

  • Liver Function Test (for Hepatitis)

  • Cholera Culture Test

  • Complete Blood Count (CBC)
     

These tests are available through SecondMedic.com and powered by trusted labs like Thyrocare, ensuring accuracy and quick results.

 

Treatment Options

Most gastrointestinal infections can be treated with:

  • Oral Rehydration Solutions (ORS) to avoid dehydration

  • Antibiotics or antiparasitic medicines (only when prescribed by a doctor)

  • Probiotics to restore healthy gut bacteria

  • Diet control, avoiding oily and spicy food during recovery
     

Avoid self-medication and always consult a healthcare provider before starting any treatment.

 

When to Seek Medical Help

See a doctor immediately if:

  • Diarrhea lasts more than 3 days

  • There is blood in stools

  • Fever exceeds 102°F

  • There are signs of dehydration

  • You experience severe abdominal pain or vomiting
     

 

Conclusion

Monsoon and humidity bring along their set of health risks—especially to the digestive system. But with a few mindful habits and hygiene practices, you can enjoy the season without falling sick. Watch what you eat and drink, maintain cleanliness, and don’t ignore symptoms.

Protect yourself and your family from gastrointestinal infections in humid weather by staying alert, eating safe, and testing when necessary.

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