Launch Of New Antiviral Against COVID-19

2-deoxy-d-glucose (2-DG) – Launch of new antiviral against COVID-19.

A new drug developed by the Defense Research and Development Organization (DRDO) in association with Dr. Reddy’s Laboratories Ltd has been launched following approval for emergency use in the treatment of Covid-19 patients by the Drug Control General of India (DCGI).

This drug is only available in India and there is no data from any other country regarding its use in COVID-19 patients.

This drug called 2-deoxy-d-glucose (2-DG) is a glucose molecule that has been modified. This drug is taken up by the virus and collects inside virus cells and prevents its replication.

This drug has not undergone a detailed clinical trial at present that’s why it has been granted not routine approval but emergency approval. Limited trial data has shown that it hastens the recovery of hospitalized patients with COVID and reduces oxygen dependence.

Most of the evidence for the molecule efficacy has come from laboratory data rather than its uses in COVID -19 patients. In the viral cell lines in the lab, it was found that they inhibited cell growth.

The drug comes in powder form in the sachet and is taken orally by dissolving it in water. This drug will be available only on prescription and only for hospitalized patients. The drug most likely will be available for use by mid-June.

We need to remember that in the last year many anti-viral and other medications came into the market to be used against COVID -19 including – hydroxychloroquine, Ivermectin, doxycycline, and azithromycin. None of these medicines were found to have any significant effect on COVD-19 patients in human trials.

Unless we have data of efficacy and safety which comes from a large clinical trial done on patients with COVID-19 patients, it will be difficult to conclude its final role in the fight against COVID-19.

Dr. Rakesh Rai.

MS, FRCS, MD, CCST, ASTS Fellow (USA).

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Stomach Ulcer Symptoms You Shouldn’t Ignore

Stomach ulcers, also called gastric ulcers, are open sores that develop on the lining of the stomach. They are a common digestive problem, affecting millions of people globally. While mild symptoms can be overlooked, ignoring them can lead to serious complications, including internal bleeding, perforation, or infection.

Common Symptoms to Watch Out For

Burning Abdominal Pain
Persistent pain or a burning sensation in the upper abdomen is the most common ulcer symptom. Pain may worsen on an empty stomach or at night.
Nausea and Vomiting
Frequent nausea, sometimes followed by vomiting, is another warning sign. In severe cases, vomit may contain blood, which indicates bleeding ulcers.
Bloating and Indigestion
Ulcers can cause the stomach to feel full quickly or bloated after meals. Indigestion and heartburn are also common.
Dark or Bloody Stools
Black, tarry, or bloody stools can be a sign of bleeding ulcers. This requires immediate medical attention.
Loss of Appetite and Weight Loss
Ulcers can reduce appetite due to discomfort while eating. Unexplained weight loss may also occur over time.

Causes and Risk Factors

Stomach ulcers develop when the stomach’s protective lining is weakened. Common causes include:

H. pylori infection – A bacterial infection that damages the stomach lining.
Excessive NSAIDs use – Painkillers like ibuprofen or aspirin can irritate the stomach.
Lifestyle factors – Smoking, alcohol, stress, and spicy food can aggravate ulcers.

Managing and Preventing Ulcers

Avoid trigger foods like alcohol, spicy meals, and caffeine.
Take medications only under doctor guidance to reduce irritation.
Manage stress with relaxation techniques or counseling.
Get regular checkups, especially if you have persistent stomach pain.

Importance of Lab Tests

Doctors often recommend lab tests to confirm ulcers and rule out other conditions. Tests may include H. pylori detection, CBC for anemia, stool tests for hidden blood, and liver/kidney function tests for safe treatment planning. Platforms like SecondMedic allow you to book these tests from home with expert guidance.

Conclusion

Ignoring stomach ulcer symptoms can lead to severe complications. Recognize warning signs such as burning pain, nausea, bloating, or blood in stools, and seek timely medical advice. Early detection and proper care can prevent serious outcomes.

If you or a loved one are experiencing digestive discomfort, consult a specialist and understand stomach ulcer symptoms you shouldn’t ignore with expert guidance from SecondMedic.

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