• Published on: Jan 23, 2022
  • 3 minute read
  • By: Second Medic Expert

Diagnostics: Kidney Function Test

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Diagnostics: Kidney function Test

Blood and urine tests are done to check kidney function.

Blood tests that can help assess kidney function include creatinine level, blood urea nitrogen level, and estimated glomerular filtration rate (eGFR).

Urine tests that can help assess kidney function include urine protein test, urine specific gravity test, and urine creatinine test.

What tests are done to check kidney function?

The most common tests to check kidney function are a blood test called creatinine and a urine test called albumin.

Creatinine is a waste product that is released into the blood when the muscle is damaged. So if the kidneys are not working properly, creatinine levels will go up. Albumin is a protein that is found in the urine. If the kidneys are not working properly, more albumin will leak out of the kidneys and into the urine.

Other tests that may be done to check kidney function include:

-A blood test to measure creatinine clearance. This measures how well the kidneys are filtering creatinine from the blood.

-A urine test to measure protein levels. High protein levels

When a doctor checks kidney function, they will order a blood test to check creatinine levels and blood urea nitrogen levels. These tests give an indication of how well the kidneys are working. If the creatinine or BUN levels are high, it means that the kidneys are not working properly. The doctor may also order a urine test to look for albumin in the urine. Albumin is a protein that is normally filtered out by the kidneys. If there is albumin in the urine, it means that the kidneys are not working properly.

What is the most accurate test for kidney function?

The most accurate test for kidney function is a creatinine blood test. It measures the level of creatinine in your blood. Creatinine is a waste product that is released when muscle tissue is damaged. So the higher your creatinine level, the more damage your kidneys have sustained.

Other tests that can be used to measure kidney function include a BUN (blood urea nitrogen) test and urine analysis. However, both tests are less accurate than the creatinine blood test.

What is a normal kidney function level?

Normal kidney function is when the kidneys filter wastes and excess fluid from the blood to make urine. The normal range for creatinine, a waste product that is filtered out by the kidneys, is 0.5 to 1.1 mg/dL for women and 0.6 to 1.2 mg/dL for men. Urine output should be about 600 to 800 mL per day. If you have symptoms such as foamy urine, swelling in your legs, shortness of breath, or chest pain, see your doctor right away because they may be signs of a problem with your kidneys.

Normal kidney function is defined as a creatinine level below 1.5 mg/dL in men and below 1.4 mg/dL in women. Creatinine is a waste product that is eliminated from the body through the kidneys. When the kidneys are functioning properly, they filter creatinine and other waste products from the blood and excrete them in urine. A creatinine level that is higher than normal indicates that the kidneys are not filtering blood as efficiently as they should be. This can be a sign of many different diseases or conditions, including kidney disease, liver disease, heart failure, and diabetes.

What are the first signs of kidney disease?

The first signs of kidney disease are usually subtle and can be easily missed. Here are five common early signs of kidney disease:

1) Changes in urine output, such as a decrease in the amount of urine produced or an increase in the amount of time needed to produce a full bladder

2) Increased thirst and urination, caused by the body's efforts to get rid of excess fluid by increasing urine production

3) Foamy or bubbly urine, a sign that protein is spilling over into the urine from damaged kidneys

4) Swelling in feet, ankles, and legs, caused by buildup of fluid called edema

5) Feeling tired and sluggish all the time, possibly due to anemia

Can a blood test detect kidney problems?

Yes. A blood test can detect kidney problems by looking for biomarkers in the blood that indicate a problem with the kidneys.

Some common biomarkers that may be detected in a blood test include creatinine, urea nitrogen, and albumin. If any of these biomarkers are elevated, it may indicate that there is a problem with the kidneys.

Kidney problems can be detected through blood tests, although the specific tests used will vary depending on the nature of the kidney problem.

Some common blood tests used to detect kidney problems include:

-A creatinine level, which measures how well your kidneys are filtering waste products from your blood

-A BUN level, which measures how much urea (a breakdown product of protein) is in your blood

-An albumin level, which measures how much albumin (a type of protein) is in your urine

-A creatinine clearance test, which measures how much creatinine is cleared from your blood per minute

Read Blog
Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

  • Gene mutations
     

  • Family-linked disease patterns
     

  • Hereditary cancer markers
     

  • Metabolic and cardiovascular risks
     

  • Neurological conditions
     

  • Autoimmune predispositions
     

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

  • Breast
     

  • Ovarian
     

  • Colorectal
     

  • Prostate
     

  • Pancreatic
     

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

  • Cholesterol levels
     

  • Plaque formation
     

  • Blood pressure regulation
     

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

  • People with family history of cancer
     

  • Individuals whose relatives had early heart attacks
     

  • Families with diabetes across generations
     

  • Women with breast or ovarian cancer history
     

  • Couples planning pregnancy
     

  • People with unexplained chronic conditions
     

  • Individuals wanting personalized preventive healthcare
     

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

  • AI-based genome interpretation
     

  • Affordable whole-genome sequencing
     

  • Predictive analytics for early cancer
     

  • Family-wide health risk mapping
     

  • Integration with digital health IDs under ABDM
     

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

  • ICMR – Genetic research insights
     

  • NIH – Genetic testing guidelines
     

  • WHO – Genomic medicine developments
     

  • Statista – DNA testing market India
     

  • SecondMedic genetic health studies

See all

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