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Published on: Jan 23, 2022
3 minute read
By: Second Medic Expert

Diagnostics: Kidney Function Test

Diagnostics: Kidney function Test

Blood and urine tests are done to check kidney function.

Blood tests that can help assess kidney function include creatinine level, blood urea nitrogen level, and estimated glomerular filtration rate (eGFR).

Urine tests that can help assess kidney function include urine protein test, urine specific gravity test, and urine creatinine test.

What tests are done to check kidney function?

The most common tests to check kidney function are a blood test called creatinine and a urine test called albumin.

Creatinine is a waste product that is released into the blood when the muscle is damaged. So if the kidneys are not working properly, creatinine levels will go up. Albumin is a protein that is found in the urine. If the kidneys are not working properly, more albumin will leak out of the kidneys and into the urine.

Other tests that may be done to check kidney function include:

-A blood test to measure creatinine clearance. This measures how well the kidneys are filtering creatinine from the blood.

-A urine test to measure protein levels. High protein levels

When a doctor checks kidney function, they will order a blood test to check creatinine levels and blood urea nitrogen levels. These tests give an indication of how well the kidneys are working. If the creatinine or BUN levels are high, it means that the kidneys are not working properly. The doctor may also order a urine test to look for albumin in the urine. Albumin is a protein that is normally filtered out by the kidneys. If there is albumin in the urine, it means that the kidneys are not working properly.

What is the most accurate test for kidney function?

The most accurate test for kidney function is a creatinine blood test. It measures the level of creatinine in your blood. Creatinine is a waste product that is released when muscle tissue is damaged. So the higher your creatinine level, the more damage your kidneys have sustained.

Other tests that can be used to measure kidney function include a BUN (blood urea nitrogen) test and urine analysis. However, both tests are less accurate than the creatinine blood test.

What is a normal kidney function level?

Normal kidney function is when the kidneys filter wastes and excess fluid from the blood to make urine. The normal range for creatinine, a waste product that is filtered out by the kidneys, is 0.5 to 1.1 mg/dL for women and 0.6 to 1.2 mg/dL for men. Urine output should be about 600 to 800 mL per day. If you have symptoms such as foamy urine, swelling in your legs, shortness of breath, or chest pain, see your doctor right away because they may be signs of a problem with your kidneys.

Normal kidney function is defined as a creatinine level below 1.5 mg/dL in men and below 1.4 mg/dL in women. Creatinine is a waste product that is eliminated from the body through the kidneys. When the kidneys are functioning properly, they filter creatinine and other waste products from the blood and excrete them in urine. A creatinine level that is higher than normal indicates that the kidneys are not filtering blood as efficiently as they should be. This can be a sign of many different diseases or conditions, including kidney disease, liver disease, heart failure, and diabetes.

What are the first signs of kidney disease?

The first signs of kidney disease are usually subtle and can be easily missed. Here are five common early signs of kidney disease:

1) Changes in urine output, such as a decrease in the amount of urine produced or an increase in the amount of time needed to produce a full bladder

2) Increased thirst and urination, caused by the body's efforts to get rid of excess fluid by increasing urine production

3) Foamy or bubbly urine, a sign that protein is spilling over into the urine from damaged kidneys

4) Swelling in feet, ankles, and legs, caused by buildup of fluid called edema

5) Feeling tired and sluggish all the time, possibly due to anemia

Can a blood test detect kidney problems?

Yes. A blood test can detect kidney problems by looking for biomarkers in the blood that indicate a problem with the kidneys.

Some common biomarkers that may be detected in a blood test include creatinine, urea nitrogen, and albumin. If any of these biomarkers are elevated, it may indicate that there is a problem with the kidneys.

Kidney problems can be detected through blood tests, although the specific tests used will vary depending on the nature of the kidney problem.

Some common blood tests used to detect kidney problems include:

-A creatinine level, which measures how well your kidneys are filtering waste products from your blood

-A BUN level, which measures how much urea (a breakdown product of protein) is in your blood

-An albumin level, which measures how much albumin (a type of protein) is in your urine

-A creatinine clearance test, which measures how much creatinine is cleared from your blood per minute

Read Blog

Pale Skin Symptoms: Causes, Health Conditions, and When to Seek Medical Care

Skin colour provides important clues about internal health. When the skin becomes noticeably lighter than usual, it may indicate an underlying medical condition. Pale skin symptoms, also referred to as pallor, are commonly associated with reduced blood flow, low hemoglobin levels or impaired oxygen delivery to tissues.

In India, pale skin is frequently linked to anemia, nutritional deficiencies and chronic illnesses, making early recognition essential.

What Is Pale Skin?

Pale skin refers to:

lighter-than-normal skin tone
reduced redness
pale appearance of lips, gums or nail beds

It can affect the entire body or specific areas such as the face or hands.

Common Pale Skin Symptoms

Typical signs include:

pale face or complexion
pale lips or tongue
light-colored gums
pale nail beds
cold hands and feet
fatigue and weakness

These symptoms often occur together.

Most Common Causes of Pale Skin

Anemia

Anemia occurs when hemoglobin levels are low.

This reduces oxygen delivery to tissues, causing:

pale skin
fatigue
breathlessness
dizziness

NFHS-5 reports anemia affects a large proportion of Indian adults, especially women.

Iron Deficiency

Iron deficiency is the leading cause of anemia.

Contributing factors include:

poor dietary intake
blood loss
absorption problems

ICMR identifies iron deficiency as a major public health issue.

Poor Blood Circulation

Reduced circulation causes:

less blood reaching the skin
visible pallor

Conditions such as heart disease or shock impair circulation.

Acute Blood Loss

Sudden blood loss from:

injury
gastrointestinal bleeding
heavy menstrual bleeding

can cause rapid pallor and weakness.

Chronic Diseases

Chronic illnesses such as:

kidney disease
liver disease
cancer

often cause anemia and pallor over time.

Infections and Inflammation

Severe infections cause:

blood vessel constriction
redistribution of blood flow

This leads to pale or clammy skin.

Nutritional Deficiencies

Deficiencies of:

vitamin B12
folate

affect red blood cell production and cause pallor.

Hormonal Imbalance

Conditions like hypothyroidism reduce metabolic activity, causing:

pale, dry skin
fatigue

Thyroid disorders are common but underdiagnosed.

Genetic Conditions

Inherited disorders such as thalassemia affect hemoglobin production, leading to chronic pallor.

Pale Skin in Children and Older Adults

Children:

may develop pallor due to iron deficiency or infections

Older adults:

often develop pallor due to chronic disease or nutritional deficiency

Both groups need careful evaluation.

Warning Signs That Need Immediate Medical Attention

Seek urgent care if pale skin is associated with:

sudden weakness
chest pain
breathlessness
fainting
rapid heartbeat

These may indicate serious medical emergencies.

How Pale Skin Affects Daily Life

Persistent pallor often causes:

low energy
reduced physical endurance
difficulty concentrating

Quality of life may decline without treatment.

Diagnostic Evaluation

Doctors may recommend:

complete blood count
iron studies
vitamin B12 and folate levels
kidney and liver function tests

Identifying the cause is critical for treatment.

Role of Preventive Health Checkups

Preventive screening helps detect:

early anemia
nutritional deficiencies
chronic disease

Early treatment prevents complications.

Management and Treatment Options

Treatment depends on cause and may include:

iron or vitamin supplementation
treatment of underlying disease
dietary correction
medical therapy for chronic conditions

Self-treatment without diagnosis should be avoided.

Lifestyle Measures to Prevent Pallor

Helpful strategies include:

balanced diet rich in iron and vitamins
adequate hydration
regular health monitoring
treating infections early

Lifestyle changes support long-term health.

Importance of Early Detection

Ignoring pale skin delays diagnosis of:

anemia
internal bleeding
chronic illness

Early recognition improves outcomes.

Conclusion

Pale skin symptoms are more than a cosmetic concern. They often signal anemia, poor circulation, nutritional deficiencies or underlying medical conditions. While temporary pallor may occur due to minor causes, persistent or sudden pale skin requires medical evaluation. Early diagnosis, preventive health screening and appropriate treatment can restore normal skin tone, improve energy levels and protect long-term health.

References

Indian Council of Medical Research (ICMR) – Anemia and Nutritional Deficiency Reports
National Family Health Survey (NFHS-5) – Anemia and Adult Health Data
World Health Organization (WHO) – Anemia and Circulatory Health
Lancet – Pallor, Anemia and Chronic Disease Research
NITI Aayog – Preventive Healthcare and Early Symptom Detection

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