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Published on: Jan 23, 2022
3 minute read
By: Second Medic Expert

Diagnostics: Kidney Function Test

Diagnostics: Kidney function Test

Blood and urine tests are done to check kidney function.

Blood tests that can help assess kidney function include creatinine level, blood urea nitrogen level, and estimated glomerular filtration rate (eGFR).

Urine tests that can help assess kidney function include urine protein test, urine specific gravity test, and urine creatinine test.

What tests are done to check kidney function?

The most common tests to check kidney function are a blood test called creatinine and a urine test called albumin.

Creatinine is a waste product that is released into the blood when the muscle is damaged. So if the kidneys are not working properly, creatinine levels will go up. Albumin is a protein that is found in the urine. If the kidneys are not working properly, more albumin will leak out of the kidneys and into the urine.

Other tests that may be done to check kidney function include:

-A blood test to measure creatinine clearance. This measures how well the kidneys are filtering creatinine from the blood.

-A urine test to measure protein levels. High protein levels

When a doctor checks kidney function, they will order a blood test to check creatinine levels and blood urea nitrogen levels. These tests give an indication of how well the kidneys are working. If the creatinine or BUN levels are high, it means that the kidneys are not working properly. The doctor may also order a urine test to look for albumin in the urine. Albumin is a protein that is normally filtered out by the kidneys. If there is albumin in the urine, it means that the kidneys are not working properly.

What is the most accurate test for kidney function?

The most accurate test for kidney function is a creatinine blood test. It measures the level of creatinine in your blood. Creatinine is a waste product that is released when muscle tissue is damaged. So the higher your creatinine level, the more damage your kidneys have sustained.

Other tests that can be used to measure kidney function include a BUN (blood urea nitrogen) test and urine analysis. However, both tests are less accurate than the creatinine blood test.

What is a normal kidney function level?

Normal kidney function is when the kidneys filter wastes and excess fluid from the blood to make urine. The normal range for creatinine, a waste product that is filtered out by the kidneys, is 0.5 to 1.1 mg/dL for women and 0.6 to 1.2 mg/dL for men. Urine output should be about 600 to 800 mL per day. If you have symptoms such as foamy urine, swelling in your legs, shortness of breath, or chest pain, see your doctor right away because they may be signs of a problem with your kidneys.

Normal kidney function is defined as a creatinine level below 1.5 mg/dL in men and below 1.4 mg/dL in women. Creatinine is a waste product that is eliminated from the body through the kidneys. When the kidneys are functioning properly, they filter creatinine and other waste products from the blood and excrete them in urine. A creatinine level that is higher than normal indicates that the kidneys are not filtering blood as efficiently as they should be. This can be a sign of many different diseases or conditions, including kidney disease, liver disease, heart failure, and diabetes.

What are the first signs of kidney disease?

The first signs of kidney disease are usually subtle and can be easily missed. Here are five common early signs of kidney disease:

1) Changes in urine output, such as a decrease in the amount of urine produced or an increase in the amount of time needed to produce a full bladder

2) Increased thirst and urination, caused by the body's efforts to get rid of excess fluid by increasing urine production

3) Foamy or bubbly urine, a sign that protein is spilling over into the urine from damaged kidneys

4) Swelling in feet, ankles, and legs, caused by buildup of fluid called edema

5) Feeling tired and sluggish all the time, possibly due to anemia

Can a blood test detect kidney problems?

Yes. A blood test can detect kidney problems by looking for biomarkers in the blood that indicate a problem with the kidneys.

Some common biomarkers that may be detected in a blood test include creatinine, urea nitrogen, and albumin. If any of these biomarkers are elevated, it may indicate that there is a problem with the kidneys.

Kidney problems can be detected through blood tests, although the specific tests used will vary depending on the nature of the kidney problem.

Some common blood tests used to detect kidney problems include:

-A creatinine level, which measures how well your kidneys are filtering waste products from your blood

-A BUN level, which measures how much urea (a breakdown product of protein) is in your blood

-An albumin level, which measures how much albumin (a type of protein) is in your urine

-A creatinine clearance test, which measures how much creatinine is cleared from your blood per minute

Read Blog

Role of Nutrition in Disease Prevention: How Food Choices Shape Long-Term Health

Disease prevention is no longer limited to vaccinations and medical screenings. Modern healthcare increasingly recognises nutrition as one of the most powerful tools for preventing illness before it begins. The role of nutrition in disease prevention is especially important in India, where lifestyle-related diseases account for a large share of premature illness and mortality.

According to the Indian Council of Medical Research (ICMR) and the National Family Health Survey (NFHS-5), poor dietary patterns contribute significantly to rising cases of diabetes, heart disease, obesity and hypertension. Unlike genetic factors, nutrition is a modifiable risk factor, meaning everyday food choices can actively protect health.

Why Nutrition Is Central to Disease Prevention

1. Nutrition regulates metabolic health

Balanced diets help maintain:

healthy blood sugar levels
optimal cholesterol balance
stable blood pressure

Disruption in these systems increases disease risk.

2. Nutrition strengthens immunity

WHO highlights that immune function depends heavily on adequate intake of vitamins, minerals and protein.

3. Nutrition controls inflammation

Chronic low-grade inflammation is linked to most lifestyle diseases. Diets rich in whole foods reduce inflammatory markers.

Major Diseases Influenced by Nutrition

Diabetes and Prediabetes

Excess refined carbohydrates and sugar drive insulin resistance.

Preventive nutrition focuses on:

whole grains
fibre-rich vegetables
adequate protein
controlled portion sizes

ICMR data shows that dietary modification can delay or prevent type 2 diabetes in high-risk individuals.

Cardiovascular Disease

Heart disease remains a leading cause of death in India.

Nutrition impacts:

cholesterol levels
blood pressure
arterial inflammation

Diets low in trans fats and high in fibre significantly reduce cardiovascular risk, as confirmed by WHO and Lancet studies.

Obesity

Obesity increases the risk of multiple chronic diseases.

Preventive nutrition addresses:

calorie density
food quality
satiety regulation

NFHS-5 reports a steady rise in overweight and obesity across age groups.

Hypertension

High sodium intake and low potassium intake contribute to high blood pressure.

Preventive dietary strategies include:

reducing processed foods
increasing fruits and vegetables
maintaining mineral balance

Certain Cancers

Diet influences cancer risk through:

antioxidant intake
fibre consumption
reduced exposure to carcinogenic compounds

WHO estimates that a significant percentage of cancers are preventable through diet and lifestyle changes.

Key Nutrients That Support Disease Prevention

Fibre

Supports gut health, blood sugar control and cholesterol reduction.

Protein

Essential for muscle health, immune function and metabolic balance.

Healthy Fats

Omega-3 fats reduce inflammation and protect heart health.

Micronutrients

Iron, zinc, vitamin D and B vitamins are essential for metabolic and immune regulation.

NFHS-5 highlights widespread micronutrient deficiencies in India, increasing disease vulnerability.

Role of Gut Health in Prevention

The gut microbiome plays a major role in:

immune regulation
inflammation control
nutrient absorption

Fermented foods and fibre-rich diets support healthy gut bacteria, strengthening disease resistance.

Why Preventive Nutrition Works Best Early

Nutrition is most effective when applied:

before disease onset
during pre-disease stages
alongside regular health screening

Once disease progresses, nutrition remains supportive but may not reverse damage fully.

Nutrition vs Medication in Prevention

Medication treats disease; nutrition reduces risk.

WHO and NITI Aayog emphasize that:

preventive nutrition reduces disease incidence
lifestyle modification lowers healthcare burden
early nutrition changes reduce dependency on long-term medication

Both approaches work best when combined appropriately.

Workplace and Community Role in Preventive Nutrition

Structured nutrition programs at workplaces and communities:

improve awareness
support behaviour change
reduce population-level disease burden

Lancet studies show that group-based nutrition interventions improve long-term adherence.

Common Myths About Nutrition and Disease Prevention

Myth 1: Supplements replace healthy food

Whole foods provide better long-term protection.

Myth 2: Prevention requires extreme diets

Consistency matters more than restriction.

Myth 3: Nutrition only matters after diagnosis

Early nutrition is most effective before disease develops.

Building a Preventive Nutrition Routine

Effective preventive nutrition includes:

regular meals
diverse food groups
portion awareness
minimal processed foods
hydration

Small daily choices compound into long-term health benefits.

Long-Term Impact of Preventive Nutrition

Consistent healthy eating leads to:

reduced disease risk
improved energy and productivity
better immune resilience
lower healthcare costs
improved quality of life

NITI Aayog identifies nutrition as a cornerstone of sustainable healthcare systems.

Conclusion

Understanding the role of nutrition in disease prevention empowers individuals to take control of their health long before illness develops. Balanced, consistent nutrition reduces inflammation, supports immunity and protects against chronic diseases that burden India’s healthcare system. Preventive nutrition is not about short-term fixes but about building lifelong habits that support health, resilience and longevity.

References

ICMR – Nutrition and Lifestyle Disease Prevention Reports
National Family Health Survey (NFHS-5) – Dietary and Metabolic Health Data
NITI Aayog – Preventive Healthcare and Nutrition Strategy Reports
WHO – Diet, Nutrition and Chronic Disease Prevention Guidelines
Lancet – Nutrition and Disease Risk Reduction Studies
Statista – Dietary Trends and Health Outcomes India
EY-FICCI – Preventive Healthcare and Nutrition Economics

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