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Published on: Apr 04, 2020
2 minute read
By: Dr Rajan Choudhary

Let's Talk COVID-19: Can Chloroquine Really Work Magic?

In the fight against COVID-19, we're looking for good medicines. One medicine we're talking about is chloroquine. Can chloroquine do something amazing against the coronavirus? In this blog, we'll talk about chloroquine and learn about the chloroquine uses, what good things it might do, and the chloroquine side effects. We want to understand how chloroquine can help in the battle against COVID-19.

Understanding Chloroquine

Chloroquine is a medicine that's usually used to treat malaria. But now, scientists are looking closely at it because they think it might help fight the coronavirus. People who study science are talking a lot about whether it could be a big help in the fight against COVID-19. They're trying to figure out if it could be a game-changer in the battle against the virus.

Chloroquine's Role in COVID-19 Treatment

Scientists have been looking into whether chloroquine and hydroxychloroquine can help treat COVID-19. These medicines are famous for fighting viruses and have done well in stopping the virus from multiplying in lab tests. But figuring out if they work the same way in real life for people is a bit tricky.

Exploring the Potential Benefits

Scientists think that chloroquine might stop the virus from getting into our cells, kind of like putting up a barrier, which could make the infection happen more slowly. Also, some studies say it might help make the symptoms of COVID-19 not as bad.

Chloroquine Uses Beyond Malaria

Chloroquine has been around in medicine for a while. It was first used to fight malaria, but because it can do different things, doctors are now looking at whether it can also help with other illnesses. The big question is if it can change from being a medicine for malaria to a strong fighter against the coronavirus.

1. Can chloroquine, once a malaria hero, now fight COVID-19 too?

Think of it as a medicine with a strong track record against one bad guy (malaria) that researchers are now considering for a new mission against another foe (COVID-19). This idea has really caught the attention of scientists and got them excited.

2. Can Chloroquine Really Help Against the Coronavirus?

In the fight against COVID-19, we want to stop the virus from getting into our cells and making copies of itself. Some smart studies suggest that chloroquine could be like a superhero, slowing down this virus-making process. This gives us hope that it could be a good treatment.

Chloroquine's Many Jobs: More Than Just Malaria!

Chloroquine isn't just a hero in the fight against malaria; it's like a superhero that's taken on new challenges, including battling COVID-19. Picture it as a versatile warrior moving from the malaria jungles to the COVID-19 battlefield. To know how powerful it can be against the coronavirus, we need to understand all the different ways it can be used. It's like figuring out all the tricks a superhero has up its sleeve!

Chloroquine Side Effects: The Flip Side of the Coin

Discovering the good things about chloroquine is interesting, but we also need to look at the not-so-good part – the side effects. Just like any medicine, chloroquine has some things we should think about.

Handling Chloroquine Side Effects

In the study by Cochrane, they stress how essential it is to know about the possible side effects of chloroquine and hydroxychloroquine. These could involve stomach problems, skin reactions, and, in rare situations, heart issues. It's like weighing the good things it can do against these possible troubles, so you can make smart decisions about your health.

So, when we talk about dealing with COVID-19, think of chloroquine as one of the players in the game. It's like a potential superhero, but hey, even superheroes have their challenges. Studies, like the one by Cochrane, give us a peek into how chloroquine fights the virus, but we're still figuring out if it's the superhero we need in the real world.

In the middle of this COVID-19 mess, it's super important to keep yourself in the loop, look at what the scientists are saying, and understand that the answer we're all looking for might not be a one-size-fits-all kind of deal. Chloroquine, with its cool past and potential, is just one piece of the puzzle in our big effort to kick COVID-19 to the curb.

As we dream about a healthier future, chloroquine's journey is like an ongoing story. The talk about how it fits into the whole COVID-19 battle is a crucial part of our ongoing chat about keeping the world healthy.

Stay connected with us for the latest updates and exclusive content! Together, let's build lasting connections!

Read FAQs

A. Initially, drugs like chloroquine and hydroxychloroquine were considered potential treatments for COVID-19. However, their effectiveness in curing the disease is still under research, and no specific drug has been proven to cure COVID-19.

A. Chloroquine is believed to have potential benefits in treating COVID-19. It may inhibit the virus's ability to enter human cells, slowing down infection. Some studies suggest it could also reduce the severity of symptoms. However, these benefits are still being studied and are not conclusive.

A. Hydroxychloroquine, like chloroquine, is an antimalarial drug. It has been explored for its potential in treating COVID-19. Studies suggest it may have antiviral properties, hindering the virus's replication. However, its specific role and effectiveness in treating COVID-19 are still being investigated, and it's not proven to be a definitive cure.

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Yellow Eyes and Skin Symptoms: Causes, Warning Signs and When to Seek Care

Yellowing of the eyes and skin is one of the most noticeable physical changes a person can experience. Often referred to as jaundice, this symptom is not a disease by itself but a sign of underlying health conditions. Understanding yellow eyes and skin symptoms is essential because they frequently indicate problems involving the liver, blood or bile ducts and may require urgent medical attention.

In India, jaundice is a common presentation across age groups due to infections, liver disease and metabolic disorders.

What Does Yellowing of Eyes and Skin Mean?

The yellow colour appears due to excess bilirubin in the blood.

Bilirubin is:

a yellow pigment
produced from the breakdown of red blood cells
processed and removed by the liver

When bilirubin builds up, it deposits in tissues, causing yellow discoloration.

Why the Eyes Turn Yellow First

The sclera, or white part of the eyes, contains elastic tissue that binds bilirubin easily.

This makes yellowing:

more visible in eyes
detectable before skin changes

Yellow eyes are often the earliest sign of jaundice.

Common Causes of Yellow Eyes and Skin

Liver-Related Causes

The liver plays a central role in bilirubin metabolism.

Common liver causes include:

viral hepatitis (A, B, C, E)
fatty liver disease
alcoholic liver disease
liver cirrhosis
drug-induced liver injury

ICMR reports viral hepatitis as a major cause of jaundice in India.

Bile Duct Obstruction

Blocked bile flow prevents bilirubin excretion.

Causes include:

gallstones
bile duct strictures
pancreatic or bile duct tumours

This type of jaundice is often associated with itching and pale stools.

Blood Disorders

Excess breakdown of red blood cells increases bilirubin production.

Conditions include:

hemolytic anemia
malaria
inherited blood disorders

The liver may be overwhelmed despite being healthy.

Infections

Certain infections directly affect liver function.

Examples include:

hepatitis viruses
leptospirosis
severe sepsis

WHO data highlights hepatitis as a leading infectious cause of jaundice globally.

Newborn and Pregnancy-Related Causes

While common in newborns, jaundice in adults always needs evaluation.

Pregnancy-related liver disorders can also cause yellowing.

Associated Symptoms That Provide Clues

Yellow eyes and skin are often accompanied by:

dark yellow or tea-coloured urine
pale or clay-coloured stools
itching
fatigue
abdominal pain
loss of appetite

These symptoms help identify the underlying cause.

When Yellowing Becomes Dangerous

Seek urgent medical care if yellowing is accompanied by:

high fever
severe abdominal pain
confusion or drowsiness
vomiting
rapid worsening of colour

These signs suggest severe liver or systemic disease.

Jaundice and Liver Function

The liver normally:

conjugates bilirubin
excretes it into bile

When liver cells are damaged, bilirubin accumulates.

Lancet studies confirm jaundice as a key marker of liver dysfunction.

Diagnostic Evaluation

Doctors evaluate jaundice using:

blood tests for bilirubin levels
liver function tests
viral markers
ultrasound or CT scans
additional tests based on findings

Early testing identifies reversible causes.

Impact on Daily Life

Persistent jaundice can affect:

energy levels
digestion
mental clarity
work performance

Untreated liver disease can progress silently.

Treatment Depends on the Cause

There is no single treatment for jaundice.

Management focuses on:

treating infection
relieving bile obstruction
stopping harmful medications
managing chronic liver disease

Self-medication can worsen liver injury.

Role of Preventive Healthcare

Preventive measures include:

hepatitis vaccination
safe drinking water
limiting alcohol intake
regular health checkups

NITI Aayog emphasises liver health in preventive care strategies.

Lifestyle Factors That Affect Liver Health

Risk factors include:

excessive alcohol
obesity
high-fat diets
unsafe injections

Addressing these reduces jaundice risk.

Importance of Early Detection

Early diagnosis:

prevents complications
improves recovery
reduces hospitalisation

Delays increase the risk of liver failure.

Jaundice Is a Symptom, Not a Diagnosis

Understanding this distinction is crucial.

Treating the symptom alone:

does not resolve the disease
may mask serious conditions

Medical evaluation is essential.

Conclusion

Yellow eyes and skin symptoms are visible warning signs that should never be ignored. Most often linked to jaundice, they reflect underlying problems involving the liver, bile ducts or blood. Early medical evaluation, accurate diagnosis and timely treatment are critical to prevent serious complications. Recognising these symptoms and seeking care promptly can protect liver health and save lives.

References

Indian Council of Medical Research (ICMR) – Hepatitis and Liver Disease Reports
World Health Organization (WHO) – Jaundice and Hepatitis Guidelines
National Family Health Survey (NFHS-5) – Liver and Metabolic Health Indicators
Lancet – Liver Function and Bilirubin Research
NITI Aayog – Non-Communicable Diseases and Liver Health
Statista – Liver Disease and Hepatitis Trends

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