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Published on: Aug 03, 2021
2 minute read
By: Second Medic Pulmonologist

What Is Mucormycosis & COVID-19 Associated With Mucormycosis ?

Mucormycosis is a rare but serious infectious disease that can be caused by inhaling spores from the ubiquitous fungi. These organisms, commonly found in soil and composts are also present on fallen leaves or animal dung. Less contagious than other types of infections, mucormycosis mainly affects people who have weakened immune systems because it cannot spread like others that do not need an outside source to enter one's body via open wounds or cuts. Mucoromyces mean "fuzz," which describes their appearance when seen under a microscope with long branching filaments called pseudohistiocysts arising off these branched threads (hyphae).

Mucormycosis is a rare but serious angio-invasive infection caused by ubiquitous fungi. The spores of these fungi can be inhaled and then infect the lungs, sinuses, or extend into brain tissue to cause mucormycosis in people who are immunocompromised. Mucoromyces has been found all over Earth with it mainly affecting those living on farms due to contact from animal dung containing high quantities of this fungus type as well as compost piles where fresh manure falls leaves cover vegetable gardening beds that may have fallen nearby leading most cases occurring near woodland areas such before dorms at college campuses were previously thought responsible for respiratory infections since they might contain bacteria like tuberculosis which also needs oxygenated.

Fungal infections, including mucormycosis, aspergillosis and invasive candidiasis, have been reported in patients with severe COVID-19 or those recovering from the disease and are associated with a high risk of serious illness. India has recently seen an increase in cases that present this way when compared to other countries where these types of fungus thrive. Prevention needs to focus on making sure people who suffer from Covid-19 maintain better glycemic control so they do not develop any fungal infection like Mucoromyces Cerealis (a subtype found more often outside India) which can cause pneumonia if untreated or brain damage if left too long without treatment because it is resistant both systemic corticosteroids/other.

Mucormycosis, an invasive fungal infection that can lead to death, has been reported in patients with severe COVID-19. The Indian government recently noted a surge of cases and the spread of this dangerous condition is attributed largely to poor glycemic control among those living with the disease or recovering from it.

Fungal infections, including mucormycosis and invasive candidiasis, have been reported in patients with severe COVID-19 or those recovering from the disease. India has seen an uptick of cases due to fungal infection caused by COVID-19 along with a surge in people who are severely affected because they were not diagnosed early on while fighting off the virus. Prevention for this type of fungus is increased monitoring when trying to apply systemic corticosteroids/other immunomodulating drugs on these patients just as much as it would be if there was no sign that someone had ARDS (acute respiratory distress syndrome).

Mucormycosis is not contagious and does not spread by contact from person to person. This fungus has been found in the environment, but transmission occurs through inhalation or ingestion of spores from the environment. Although most cases are sporadic, healthcare-associated outbreaks have occurred after the use of adhesive bandages made out wood tongue depressors as well as linens with lackadaisical hygiene standards at hospitals that result in fungal exposure on surfaces like walls and floors which can lead to airborne infection if those areas aren't properly cleaned up soon enough. Mucormicosis primarily affects sinuses or lungs after inhaling spores from air when it's breathed directly into them.

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Difference Between Sadness and Depression: Understanding Normal Emotions vs Mental Illness

Feeling low or unhappy is a part of being human. However, not all low moods are the same. Many people confuse sadness with depression, which can delay proper support and treatment. Understanding the difference between sadness and depression is crucial for mental health awareness, early intervention and reducing stigma.

In India, mental health conditions are often misunderstood, with emotional distress frequently dismissed as temporary sadness.

What Is Sadness?

Sadness is a normal human emotion.

It usually occurs due to:

loss or disappointment
relationship issues
failure or stress
temporary life challenges

Sadness serves a psychological purpose, allowing individuals to process emotions and adapt.

Key Characteristics of Sadness

Sadness is:

situational
temporary
emotionally painful but manageable
responsive to support and positive events

A person experiencing sadness can still function, enjoy moments and feel hopeful.

What Is Depression?

Depression is a medical condition classified as a mood disorder.

It affects:

emotions
thinking patterns
behaviour
physical health

According to WHO, depression is one of the leading causes of disability worldwide.

Core Symptoms of Depression

Depression involves a combination of symptoms such as:

persistent low mood
loss of interest or pleasure
fatigue
sleep disturbances
appetite changes
feelings of worthlessness
difficulty concentrating

These symptoms last at least two weeks or longer.

Duration: A Key Difference

One major difference lies in duration.

Sadness:

lasts hours or days
improves with time

Depression:

lasts weeks or months
persists despite positive events

Duration helps distinguish emotional response from illness.

Impact on Daily Functioning

Sadness:

allows continuation of work and relationships
may reduce motivation temporarily

Depression:

interferes with work, studies and relationships
reduces self-care and productivity

Functional impairment is a defining feature of depression.

Emotional Experience: Sadness vs Depression

Sadness:

allows emotional range
moments of joy still occur

Depression:

creates emotional numbness
joy and interest disappear

People with depression often describe feeling empty rather than sad.

Physical Symptoms in Depression

Depression is not only emotional.

Physical symptoms include:

chronic fatigue
body aches
headaches
digestive issues

ICMR mental health studies highlight the physical burden of depression.

Thought Patterns and Self-Perception

Sadness:

thoughts remain realistic
self-worth is preserved

Depression:

negative self-talk dominates
feelings of guilt and worthlessness increase

These cognitive changes deepen emotional suffering.

Risk Factors for Depression

Factors increasing depression risk include:

chronic stress
trauma
family history
medical illnesses
hormonal changes

NFHS-5 data indicates rising mental health concerns among young adults.

Can Sadness Turn Into Depression?

Yes, prolonged or unresolved sadness can progress into depression.

This is more likely when:

stressors are ongoing
support systems are weak
coping mechanisms are limited

Early emotional support can prevent progression.

When to Seek Professional Help

Seek help if:

low mood lasts more than two weeks
daily functioning is affected
sleep and appetite are disturbed
thoughts of self-harm occur

Early care leads to better outcomes.

Treatment Differences

Sadness:

improves with rest, support and time

Depression:

requires psychotherapy
may need medication
benefits from structured care

WHO emphasises early treatment to reduce disability.

Role of Social Support

Support systems help both conditions but are essential for recovery.

Depression recovery improves with:

understanding family
supportive workplaces
accessible mental healthcare

Stigma reduction is key.

Mental Health Awareness in India

Mental health remains underdiagnosed in India.

NITI Aayog reports:

limited access to mental health services
low awareness
high stigma

Education helps bridge this gap.

Importance of Early Recognition

Recognising depression early:

prevents worsening
reduces suicide risk
improves quality of life

Delay increases suffering and complications.

Supporting Someone With Depression

Helpful actions include:

listening without judgement
encouraging professional help
avoiding minimising feelings

Compassion is more effective than advice.

Conclusion

Understanding the difference between sadness and depression is essential for emotional wellbeing and mental health care. Sadness is a natural, temporary response to life events, while depression is a serious medical condition that affects thoughts, emotions and daily functioning. Recognising the signs early and seeking appropriate help can prevent long-term suffering and promote recovery. Mental health deserves the same attention and care as physical health.

References

World Health Organization (WHO) – Depression and Mental Health Disorders
Indian Council of Medical Research (ICMR) – Mental Health Research and Burden
National Family Health Survey (NFHS-5) – Mental Health Indicators
Lancet – Depression, Disability and Public Health
NITI Aayog – National Mental Health Policy and Awareness Reports
Statista – Global and Indian Mental Health Trends

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