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Published on: May 17, 2025
3 minute read
By: Secondmedic Expert

Top 5 Blood Tests You Shouldn’t Skip After 40

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As we grow older, our bodies go through many changes — some are visible, like graying hair or slower metabolism, but others happen quietly inside. After the age of 40, the risk of lifestyle-related diseases such as diabetes, heart disease, thyroid disorders, and kidney problems increases significantly. The good news? Most of these conditions can be detected early with simple blood tests.

Regular health checkups and blood tests can help you stay ahead of potential problems. They can alert you before symptoms even begin, giving you the chance to take control of your health in time.

In this blog, we’ll look at the Top 5 blood tests you shouldn’t skip after 40, why they’re important, and how you can easily get them done — even from the comfort of your home.

1. Complete Blood Count (CBC)

What is it?
The Complete Blood Count is a common blood test that checks the levels of different cells in your blood — red blood cells, white blood cells, and platelets.

Why is it important after 40?

Detects anemia, which is common in both men and women over 40
Helps identify infections and inflammatory conditions
Can point toward more serious issues like blood cancer in rare cases

What it includes:

Hemoglobin
Hematocrit
White blood cell (WBC) count
Platelet count

How often to test:
Once a year, or as advised by your doctor.

2. Blood Sugar Tests – Fasting & HbA1c

What is it?
These tests measure the amount of glucose (sugar) in your blood. The fasting blood sugar test checks your sugar level after 8–10 hours of fasting, while the HbA1c test shows your average sugar level over the past 2-3 months.

Why is it important after 40?

Type 2 diabetes is very common in people above 40, especially in India
Early detection can prevent complications like nerve damage, eye problems, and kidney disease
Many people have prediabetes and don’t even know it

What it includes:

Fasting Blood Glucose (FBS)
Postprandial Blood Sugar (PPBS)
HbA1c

How often to test:
Every 6–12 months, or more often if you're overweight, have a family history, or symptoms of diabetes.

3. Lipid Profile (Cholesterol Test)

What is it?
A lipid profile checks the levels of different types of fats (lipids) in your blood — especially cholesterol and triglycerides.

Why is it important after 40?

Helps assess your risk of heart disease, stroke, and artery blockages
Detects high LDL ("bad cholesterol"), which builds up in arteries
Encourages healthy lifestyle changes before medications are needed

What it includes:

Total cholesterol
LDL (Low-Density Lipoprotein)
HDL (High-Density Lipoprotein)
Triglycerides

How often to test:
Once a year, or every 6 months if you're overweight, smoke, or have a family history of heart issues.

4. Liver Function Test (LFT)

What is it?
This test checks how well your liver is working. The liver is responsible for digesting food, filtering toxins, and regulating many body processes.

Why is it important after 40?

Modern lifestyle increases the risk of fatty liver disease, even in non-drinkers
Long-term use of medications, alcohol, or unhealthy diets can silently damage the liver
Detects hepatitis, jaundice, and other liver issues early

What it includes:

SGPT (ALT), SGOT (AST)
Bilirubin
Alkaline Phosphatase
Albumin

How often to test:
Once a year or as recommended, especially if you drink alcohol, are overweight, or take regular medications.

5. Kidney Function Test (KFT)

What is it?
This test checks how well your kidneys are filtering waste and balancing fluids in your body.

Why is it important after 40?

Kidneys often get damaged silently due to high blood pressure, diabetes, or painkillers
Early detection can prevent serious kidney damage or the need for dialysis
Many Indians are at risk of chronic kidney disease (CKD) without knowing it

What it includes:

Blood Urea
Serum Creatinine
Uric Acid
Electrolytes (Sodium, Potassium)
eGFR (Estimated Glomerular Filtration Rate)

How often to test:
Yearly, especially if you have diabetes, high blood pressure, or a family history of kidney problems.

Other Important Tests After 40

While the above 5 are essential, don’t ignore these additional tests:

Thyroid Function Test (TSH, T3, T4) – for energy, weight, and mood balance
Vitamin D & B12 – deficiencies are common in Indian adults
ECG or TMT – if you feel chest pain or breathlessness
Prostate Test (PSA) – for men over 45
Pap Smear & Mammogram – for women to detect cervical and breast cancer

How to Book These Tests Easily in India

Getting a blood test today is simple and stress-free. You don’t even need to visit a lab anymore.

At SecondMedic, you can:

Book blood tests online through our website
Get home sample collection by trained professionals
View your digital reports online within 24–48 hours
Consult our doctors based on your results

Conclusion

Turning 40 is a milestone — and a reminder that your health needs attention. Don’t wait for symptoms. These simple blood tests can alert you to hidden problems and help you take action before it’s too late.

Remember, good health starts with awareness. Be proactive, not reactive.

If you care about your long-term well-being, Top 5 Blood Tests You Shouldn’t Skip After 40 should be part of your annual health routine. Book them today on SecondMedic and stay a step ahead in your health journey.

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Read FAQs

A. After 40, the most important blood tests include Complete Blood Count (CBC), Fasting Blood Sugar & HbA1c, Lipid Profile, Liver Function Test (LFT), and Kidney Function Test (KFT).

A. It's recommended to get a full set of preventive blood tests at least once a year. If you have risk factors like diabetes, hypertension, or family history of chronic disease, more frequent testing may be needed.

A. Yes, platforms like SecondMedic offer home sample collection for blood tests across India. You can book tests online and receive digital reports within 24–48 hours.

A. Most of these tests are affordable and are also available in bundled health checkup packages. Prices range from ₹500 to ₹2000 depending on the tests and provider.

A. Many chronic diseases like diabetes, kidney damage, or fatty liver show no symptoms in the early stages. Regular blood tests help detect these issues early, improving chances of effective treatment or reversal.

Read Blog

Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

Gene mutations
Family-linked disease patterns
Hereditary cancer markers
Metabolic and cardiovascular risks
Neurological conditions
Autoimmune predispositions

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

Breast
Ovarian
Colorectal
Prostate
Pancreatic

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

Cholesterol levels
Plaque formation
Blood pressure regulation

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

People with family history of cancer
Individuals whose relatives had early heart attacks
Families with diabetes across generations
Women with breast or ovarian cancer history
Couples planning pregnancy
People with unexplained chronic conditions
Individuals wanting personalized preventive healthcare

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

AI-based genome interpretation
Affordable whole-genome sequencing
Predictive analytics for early cancer
Family-wide health risk mapping
Integration with digital health IDs under ABDM

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

ICMR – Genetic research insights
NIH – Genetic testing guidelines
WHO – Genomic medicine developments
Statista – DNA testing market India
SecondMedic genetic health studies

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