Call
+918447748545

Published on: Apr 28, 2020
4 minute read
By: Dr Rajan Choudhary

Strokes In The Young And How COVID Causing Clotting Disorders?

Strokes in the young and healthy: how is COVID causing clotting disorders?

In the news, there has been a rush in stories linking Strokes in young and healthy patients, patients who also have COIVD-19. This is certainly worrying news, and at first glance, it is difficult to explain. How does a respiratory virus, one that is very similar to the coronavirus responsible for the common cold, cause such serious issues in a completely unrelated organ system? In this two-part series we will first go over the basics of clotting and its function, how clotting can cause problems, and finally how COVID can lead to clotting disorders.

STROKES

Before we progress, if you or a family member are having any of the following symptoms, contact your local emergency services immediately. Strokes can be devastating, and treatment needs to be given as soon as possible to save as much of the brain as we can. Early recognition can be the difference between manageable long term effects and crippling disability.

Remember, act F.A.S.T

Facial Droop on one side
Arm or hand on one side feels numb or weak with reduced power (same in one leg)
Slurred speech making it difficult to understand
Time to phone an ambulance

Other symptoms can include sudden loss in balance, sudden loss in vision in one eye, problems swallowing, and more.

PLUGGING A HOLE

We have an intricate network of vessels to transport oxygen, nutrients, and signals to cells and organs across our bodies. Damage to these blood vessels causes blood loss, reduction in oxygen and nutrient delivery to these cells, and organ damage if the issue isn’t rectified. Failure in multiple organ systems across the body will eventually lead to death. Our blood has cells and proteins that work together to form a clot at the site of injury. This acts as a plug to physically stop the leak, but also encourages repair of the blood vessel and surrounding tissue.

A clot can be triggered in three different ways: blood stasis (pooling up in one area), exposure of blood vessel lining, and pro-coagulant factors released into the blood. When triggered a coagulation cascade occurs to form the building blocks of a clot – it works so well that even a small trigger can create a response big enough to repair the damage. These form a mesh trapping platelets and other blood cells into a plug. Immune cells also arrive to destroy any organisms that might enter from the trauma site that caused the injury, and these immune cells also instruct nearby cells to begin the repair process.

As with everything in our body the whole process is very tightly regulated. The cascade has triggers and accelerators, but it also has brakes. These brakes stop a clot from growing too big, or from clots forming spontaneously when they are not needed. They also help dissolve a clot once the vessel is repaired and it isn’t needed.

WHEN IT GOES WRONG

Heart attacks and strokes. These devastating cardiovascular diseases are well recognized by the public as a leading cause of disability and death. Both can be caused by abnormal clotting. How does our finely tuned clotting cascade turn abnormal? Let's go back to the three triggers of blood clotting.

Vessel damage: Eating a high fat and cholesterol diet can cause fatty plaques to build up in our arteries. This is known as atherosclerosis, and it is extremely common. The plaques can narrow your arteries and reduce blood flow. If this happens in your coronary arteries supplying your heart muscles, your heart might not receive enough oxygen when you exercise or exert yourself. This can cause chest pain, known as angina.

If the plaques burst open it can expose the vessel lining, causing a large clot to form. This clot can become dislodged and be carried away by the blood. It will eventually get lodged in a narrow artery, blocking it and stopping blood from entering. The tissue and cells supplied by that artery will not receive oxygen and eventually die. If this happens in the coronary arteries it can cause a heart attack. In the arteries supplying the brain, it can cause a stroke, leading to neurological deficits.

THIS IS THE MOST IMPORTANT LEARNING POINT, and this is why a healthy diet low in fat and sugars is so important.

Stasis: Our heart pumps blood at high pressures through the arteries. But in the veins, there is very little pressure to drive the blood back to the heart. In our arms and head, gravity helps blood flow down to the heart. But from our legs? When we walk the muscles in our legs squeeze the veins and move the blood. Valves make sure this flow is only one way, back to the heart.

If we sit or lie down in one place and don’t move, the blood isn’t pumped back and pools up in our legs, causing a clot to form. This usually happens in our calves (known as a DEEP VEIN THROMBOSIS, or DVT). The calf becomes swollen, painful, red, and hot. If this clot is dislodged, it can end up in our lungs causing a PULMONARY EMBOLISM. A large PE can block blood from entering the lungs and can be fatal. This is why you should take regular walks on long haul flights, to prevent blood from pooling.

Pro-coagulant: Sometimes the factors in our blood responsible for triggering a clot can be triggered accidentally. Cigarette smoke contains many toxins and harmful chemicals that, when inhaled, end up in your blood. These chemicals can cause damage to vessel linings, and also cause the clotting cascade to be triggered more easily. Some medications, such as the Combined Oral Contraceptive Pill, also have a similar effect, though the risk of getting a clot is still very low.

The immune system can also trigger a clot. The protein mesh formed in the blood can also capture bacteria and viruses around an infection site, making it easier for immune cells to find and destroy these invading organisms. In cancer patients, this process is sometimes triggered by unregulated cancer cells.

WHAT HAVE WE LEARNT?

Our clotting system stops us from bleeding to death from a small wound. People who have bleeding disorders are clear examples and need to be extremely careful if they injure themselves. But unregulated, our body can end up harming itself. If there is one thing you should take away from this, it is that a high sugar/high-fat diet with little exercise can directly increase your risk of having a heart attack or stroke. This is why doctors emphasize so much the importance of a good diet and exercise.

In our next blog, we will look at how this clotting problem is implicated in COVID patients.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

Read Blog

AI-Based Disease Detection India: How SecondMedic Is Transforming Early Diagnosis

India’s healthcare landscape is evolving rapidly, with artificial intelligence emerging as one of the most powerful tools for early disease detection. AI-based disease detection India represents a major shift from reactive healthcare to predictive, preventive, and precise medical analysis. Instead of waiting for symptoms to appear, AI enables clinicians and patients to identify risks early through advanced data interpretation.

Rising chronic diseases, increased diagnostic loads, and limited specialist availability make AI essential for early diagnosis in India. The use of AI in medical imaging, risk scoring, and pattern recognition significantly enhances accuracy while reducing time-consuming manual processes. SecondMedic integrates AI-powered diagnostic tools to help individuals detect health conditions in their earliest stages, enabling timely intervention and improved long-term outcomes.

Why India Needs AI-Based Disease Detection

India faces one of the world’s highest burdens of chronic and lifestyle diseases. Many conditions remain undiagnosed until they reach advanced stages, often due to late screenings, limited access to specialists, or lack of early symptoms.

The need for AI-based detection is driven by:

High incidence of silent diseases like diabetes and hypertension
Overloaded healthcare systems
Limited availability of expert radiologists
Rising lifestyle risk factors
Increasing demand for precision diagnostics
Need for faster, more accurate analysis

AI bridges these gaps by providing early alerts, consistent accuracy, and fast interpretations.

How AI Detects Diseases Early

AI-based disease detection uses machine learning models trained on thousands of medical datasets. These models learn to recognize abnormal patterns and subtle changes that the human eye might overlook.

AI analyzes:

Blood test patterns
Vital signs and wearable data
Imaging scans (X-rays, MRIs, CT scans)
Medical history
Genetic predispositions
Lifestyle habits

Through advanced algorithms, AI can identify risks long before symptoms appear, giving patients critical time for prevention and treatment.

AI in Medical Imaging: A Major Breakthrough for India

Medical imaging AI has transformed diagnosis speed and accuracy. In India, where access to radiologists is uneven, AI helps bridge diagnostic gaps.

AI-assisted imaging helps detect:

Lung infections and tuberculosis
Early-stage cancer indicators
Cardiac abnormalities
Brain tumors and neurological issues
Bone fractures and musculoskeletal conditions
Liver and kidney anomalies

SecondMedic uses AI-supported imaging interpretation to enhance precision and reduce reporting delays.

AI for Chronic Disease Prediction

Chronic illnesses often develop silently. By analyzing long-term trends, AI can predict disease progression and alert patients earlier.

AI helps forecast:

Prediabetes to diabetes progression
Heart attack risk
Hypertension development
Chronic kidney disease
Thyroid dysfunction
Metabolic health decline

These predictions allow individuals to take preventive action far in advance.

Personalized Disease Detection with AI

AI enables personalized diagnostics by incorporating each user’s biological and lifestyle data into prediction models.

Personalized AI detection considers:

Age and family history
Diet and activity levels
Sleep patterns
Stress levels
Blood markers
Genetic factors

This creates a highly individualized health risk profile.

SecondMedic’s AI engine creates a personalized risk score for each user, allowing targeted preventive strategies.

AI for Cancer Early Detection

Cancer often goes undiagnosed until it reaches advanced stages. AI helps detect early warning signs by analyzing subtle abnormalities.

AI supports early cancer detection in:

Breast cancer (mammograms)
Cervical cancer (Pap tests and visual scans)
Lung cancer (X-rays and CT scans)
Colon cancer indicators
Skin cancer lesion analysis

This improves survival rates by supporting early diagnosis.

Real-Time Monitoring with AI

Continuous monitoring is essential for early disease detection. AI integrates with wearable devices and digital health tools to track vital parameters in real time.

AI monitors:

Heart rate trends
Oxygen levels
Blood pressure variations
Stress levels
Sleep quality
Blood glucose fluctuations (connected devices)

Real-time alerts notify users of abnormalities that require attention.

AI in Public Health Disease Detection

AI is also used at the population level to identify disease patterns and outbreaks.

AI supports public health by:

Predicting outbreak patterns
Analyzing environmental health impact
Tracking regional disease trends
Supporting government screening programs

This strengthens India’s preventive health strategy.

How SecondMedic Uses AI for Disease Detection

SecondMedic integrates AI tools throughout its digital healthcare ecosystem, helping individuals access early detection and preventive insights.

SecondMedic’s AI capabilities include:

Risk scoring for diseases
AI analysis of medical reports
Predictive analytics dashboards
Early-warning alerts
Integration with wearables
AI-supported doctor consultations

This helps users understand risks clearly and take action early.

Challenges in AI-Based Disease Detection

While AI offers powerful benefits, it must be used responsibly.

Challenges include:

Requirement of high-quality medical data
Need for clinical validation
Maintaining data privacy
Avoiding algorithmic bias
Ensuring user awareness and understanding

SecondMedic follows ethical AI practices aligned with DPDP Act and ABDM standards.

Future of AI-Based Disease Detection in India

AI will continue to redefine diagnostics in India over the next decade.

Future developments include:

Deep AI for full-body scan interpretation
Genomic-based AI predictions
Emotion and mental health detection through AI
AI-assisted virtual triage systems
At-home AI diagnostic kits
National integrated AI health platforms

SecondMedic aims to lead in these innovations by integrating advanced predictive tools.

Conclusion

AI-based disease detection India is shaping a new era of proactive healthcare. By analyzing health patterns, detecting abnormalities early, and providing accurate risk assessment, AI empowers individuals to act before diseases progress. SecondMedic uses AI-driven diagnostic tools to support early detection, preventive care, and long-term health protection.

To explore AI-powered diagnostic support, visit www.secondmedic.com

References

NITI Aayog – AI for Healthcare in India
WHO – AI in Early Disease Detection
ICMR – Chronic Disease Patterns India
IMARC – Indian AI Healthcare Market
FICCI – AI and Precision Medicine India

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.