• Published on: Apr 28, 2020
  • 4 minute read
  • By: Dr Rajan Choudhary

Strokes In The Young And How COVID Causing Clotting Disorders?

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Strokes in the young and healthy: how is COVID causing clotting disorders?

In the news, there has been a rush in stories linking Strokes in young and healthy patients, patients who also have COIVD-19. This is certainly worrying news, and at first glance, it is difficult to explain. How does a respiratory virus, one that is very similar to the coronavirus responsible for the common cold, cause such serious issues in a completely unrelated organ system? In this two-part series we will first go over the basics of clotting and its function, how clotting can cause problems, and finally how COVID can lead to clotting disorders.

STROKES

Before we progress, if you or a family member are having any of the following symptoms, contact your local emergency services immediately. Strokes can be devastating, and treatment needs to be given as soon as possible to save as much of the brain as we can. Early recognition can be the difference between manageable long term effects and crippling disability.

Remember, act F.A.S.T

  • Facial Droop on one side
  • Arm or hand on one side feels numb or weak with reduced power (same in one leg)
  • Slurred speech making it difficult to understand
  • Time to phone an ambulance

Other symptoms can include sudden loss in balance, sudden loss in vision in one eye, problems swallowing, and more.

PLUGGING A HOLE

We have an intricate network of vessels to transport oxygen, nutrients, and signals to cells and organs across our bodies. Damage to these blood vessels causes blood loss, reduction in oxygen and nutrient delivery to these cells, and organ damage if the issue isn’t rectified. Failure in multiple organ systems across the body will eventually lead to death. Our blood has cells and proteins that work together to form a clot at the site of injury. This acts as a plug to physically stop the leak, but also encourages repair of the blood vessel and surrounding tissue.

A clot can be triggered in three different ways: blood stasis (pooling up in one area), exposure of blood vessel lining, and pro-coagulant factors released into the blood. When triggered a coagulation cascade occurs to form the building blocks of a clot – it works so well that even a small trigger can create a response big enough to repair the damage. These form a mesh trapping platelets and other blood cells into a plug. Immune cells also arrive to destroy any organisms that might enter from the trauma site that caused the injury, and these immune cells also instruct nearby cells to begin the repair process.

As with everything in our body the whole process is very tightly regulated. The cascade has triggers and accelerators, but it also has brakes. These brakes stop a clot from growing too big, or from clots forming spontaneously when they are not needed. They also help dissolve a clot once the vessel is repaired and it isn’t needed.

WHEN IT GOES WRONG

Heart attacks and strokes. These devastating cardiovascular diseases are well recognized by the public as a leading cause of disability and death. Both can be caused by abnormal clotting. How does our finely tuned clotting cascade turn abnormal? Let's go back to the three triggers of blood clotting.

Vessel damage: Eating a high fat and cholesterol diet can cause fatty plaques to build up in our arteries. This is known as atherosclerosis, and it is extremely common. The plaques can narrow your arteries and reduce blood flow. If this happens in your coronary arteries supplying your heart muscles, your heart might not receive enough oxygen when you exercise or exert yourself. This can cause chest pain, known as angina.

If the plaques burst open it can expose the vessel lining, causing a large clot to form. This clot can become dislodged and be carried away by the blood. It will eventually get lodged in a narrow artery, blocking it and stopping blood from entering. The tissue and cells supplied by that artery will not receive oxygen and eventually die. If this happens in the coronary arteries it can cause a heart attack. In the arteries supplying the brain, it can cause a stroke, leading to neurological deficits.

THIS IS THE MOST IMPORTANT LEARNING POINT, and this is why a healthy diet low in fat and sugars is so important. 

Stasis: Our heart pumps blood at high pressures through the arteries. But in the veins, there is very little pressure to drive the blood back to the heart. In our arms and head, gravity helps blood flow down to the heart. But from our legs? When we walk the muscles in our legs squeeze the veins and move the blood. Valves make sure this flow is only one way, back to the heart.

If we sit or lie down in one place and don’t move, the blood isn’t pumped back and pools up in our legs, causing a clot to form. This usually happens in our calves (known as a DEEP VEIN THROMBOSIS, or DVT). The calf becomes swollen, painful, red, and hot. If this clot is dislodged, it can end up in our lungs causing a PULMONARY EMBOLISM. A large PE can block blood from entering the lungs and can be fatal. This is why you should take regular walks on long haul flights, to prevent blood from pooling.

Pro-coagulant: Sometimes the factors in our blood responsible for triggering a clot can be triggered accidentally. Cigarette smoke contains many toxins and harmful chemicals that, when inhaled, end up in your blood. These chemicals can cause damage to vessel linings, and also cause the clotting cascade to be triggered more easily. Some medications, such as the Combined Oral Contraceptive Pill, also have a similar effect, though the risk of getting a clot is still very low.

The immune system can also trigger a clot. The protein mesh formed in the blood can also capture bacteria and viruses around an infection site, making it easier for immune cells to find and destroy these invading organisms. In cancer patients, this process is sometimes triggered by unregulated cancer cells.

WHAT HAVE WE LEARNT?

Our clotting system stops us from bleeding to death from a small wound. People who have bleeding disorders are clear examples and need to be extremely careful if they injure themselves. But unregulated, our body can end up harming itself. If there is one thing you should take away from this, it is that a high sugar/high-fat diet with little exercise can directly increase your risk of having a heart attack or stroke. This is why doctors emphasize so much the importance of a good diet and exercise.

In our next blog, we will look at how this clotting problem is implicated in COVID patients.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Lipid Profile Test

Lipid Profile Test – Normal Range and Risks

Keeping your heart healthy isn’t just about staying active or eating green veggies. It also means knowing what’s going on inside your body—especially your cholesterol levels. One of the best ways to track this is through a lipid profile test.

If you’re wondering what this test means, what the numbers should be, and what risks you face if they're abnormal—this blog is for you.

Let’s dive into lipid profile test – normal range and risks in easy and clear language.

 

What Is a Lipid Profile Test?

A lipid profile test is a blood test that measures the amount of fat (lipids) in your blood. These lipids include different types of cholesterol and triglycerides.

The test helps evaluate your risk of heart disease, stroke, and clogged arteries.

 

What Does the Lipid Profile Test Measure?

A complete lipid profile usually measures:

  1. Total Cholesterol – the overall amount of cholesterol in your blood
     

  2. LDL (Low-Density Lipoprotein) – the “bad” cholesterol that can block arteries
     

  3. HDL (High-Density Lipoprotein) – the “good” cholesterol that protects your heart
     

  4. Triglycerides – a type of fat that provides energy but can cause heart issues in high amounts
     

Sometimes, the test also calculates VLDL and a cholesterol/HDL ratio to better assess your health risks.

 

Lipid Profile – Normal Range

Understanding what your numbers mean is key. Here are the recommended normal ranges:

Test Component

Normal Range

Total Cholesterol

Less than 200 mg/dL

LDL (Bad Cholesterol)

Less than 100 mg/dL

HDL (Good Cholesterol)

40 mg/dL or more (men), 50+ (women)

Triglycerides

Less than 150 mg/dL

Note: Values may vary slightly depending on labs and age. Always consult your doctor for interpretation.

 

Why Is This Test Important?

High cholesterol usually shows no symptoms. That’s why it's called a silent threat.

Your arteries may slowly get clogged without you knowing it, increasing the risk of:

  • Heart attacks
     

  • Strokes
     

  • Peripheral artery disease
     

  • High blood pressure
     

A lipid profile gives an early warning so you can make timely changes to protect your heart.

 

Risks of Abnormal Lipid Profile

Here’s what happens when the results are not in the normal range:

High LDL Cholesterol

  • Builds plaque in your arteries
     

  • Increases risk of heart attack or stroke
     

Low HDL Cholesterol

  • Reduces protection for your heart
     

  • Makes it easier for bad cholesterol to stick to artery walls
     

High Triglycerides

  • Can lead to pancreatitis and diabetes
     

  • Often linked with obesity and poor lifestyle
     

High Total Cholesterol

  • General risk marker for cardiovascular diseases
     

 

Causes of High Cholesterol or Triglycerides

  • Unhealthy diet (high in fried, fatty, and sugary foods)
     

  • Lack of physical activity
     

  • Smoking and alcohol consumption
     

  • Obesity
     

  • Diabetes or thyroid problems
     

  • Genetic/family history of high cholesterol
     

 

How to Improve Your Lipid Profile Naturally

If your test results are abnormal, you don’t always need medicine right away. Often, small changes in your lifestyle can bring big improvements.

Eat a Heart-Healthy Diet

  • Choose whole grains, fruits, vegetables, and lean proteins
     

  • Avoid processed food, red meat, and fried items
     

  • Include omega-3 rich foods like fish, flaxseeds, and walnuts
     

Exercise Regularly

  • 30 minutes of walking, yoga, cycling, or swimming at least 5 days a week
     

Quit Smoking & Limit Alcohol

  • These habits lower HDL and increase LDL
     

Maintain a Healthy Weight

  • Losing even 5–10% of body weight can improve lipid levels
     

 

How and When to Take the Lipid Profile Test

When to Take:

  • Once every 12 months for adults above 30
     

  • More often if you have heart disease, diabetes, obesity, or a family history
     

Fasting Required?

Yes, you should fast for 8–12 hours before giving the blood sample for the most accurate results.

 

Can I Get This Test at Home?

Yes! Platforms like SecondMedic.com offer home sample collection for the Lipid Profile Test, powered by trusted labs like Thyrocare.

You just book the test online, and a technician collects the sample from your doorstep. Results are available digitally within 24–48 hours.

Total cholesterol over 240 mg/dL, LDL over 160 mg/dL, and triglycerides over 200 mg/dL are considered high-risk levels.

 

Conclusion

A lipid profile test is a simple yet powerful tool that gives deep insights into your heart health. Knowing the normal range and understanding the risks of abnormal levels can help you take control early and live a longer, healthier life.

Stay proactive about your health. Book a lipid profile test – normal range and risks checkup today and make heart-smart choices.

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