• Published on: May 05, 2024
  • 2 minute read
  • By: SecondMedic Expert

Role Of Kidney Function Tests In Chronic Kidney Disease (CKD)

  • WhatsApp share link icon
  • copy & share link icon
  • twitter share link icon
  • facebook share link icon

The progressive loss of kidney function over time is the hallmark of chronic kidney disease (CKD). In order to limit the progression of CKD and avoid complications, it is essential to recognize the condition early and monitor it regularly. Renal function tests, also referred to as kidney function tests or KFTs (Kidney Function Tests), are essential for the diagnosis and treatment of chronic kidney disease (CKD). This article examines the role that kidney function tests play in the evaluation of chronic kidney disease (CKD) phases and the importance of test results in the efficient management of this illness.

Importance of Kidney Function Tests in CKD Diagnosis

A series of blood and urine tests known as kidney function tests are used to evaluate the kidneys' overall health. By assessing certain indicators including creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR), and urine protein levels, these tests offer insightful information on kidney health. Kidney function tests aid in the diagnosis of chronic kidney disease (CKD) by detecting changes in kidney function prior to the onset of symptoms.

Key Markers in Kidney Function Tests

Creatinine: The kidneys' capacity to remove waste from the blood is reflected in the levels of serum creatinine. High levels of creatinine signify compromised kidney function, a characteristic of chronic renal disease.
Blood Urea Nitrogen (BUN): Urea is a waste product of protein metabolism. BUN levels indicate how much nitrogen is derived from urea in the blood. Reduced renal function may be indicated by elevated BUN levels.
Age, gender, race, and creatinine levels are used to calculate the estimated glomerular filtration rate, or eGFR. It calculates the kidneys' efficiency at removing waste from the blood. When CKD is staged, a low eGFR is indicative of diminished kidney function.
Urine Protein (Proteinuria): Proteinuria is a symptom of renal disease that can be identified by urine tests. A high protein level in the urine is indicative of a compromised kidney's filtration capacity.

Stages of CKD Based on Kidney Function Tests

Based on eGFR scores, kidney function tests are essential for classifying CKD into stages:
Stage 1 (Kidney Damage with Normal eGFR): eGFR (>90 mL/min/1.73 m2) is normal despite the presence of kidney damage.
Stage 2 (moderately impaired eGFR): eGFR 60-89 mL/min/1.73 m?2; indicates a moderately impaired kidney function.
Stage 3 (Moderately Reduced eGFR): eGFR of 30-59 mL/min/1.73 m?2; indicates a moderate decline in kidney function.
Severe loss in kidney function (eGFR 15-29 mL/min/1.73 m2) is shown in Stage 4 (Severely Reduced eGFR).
Kidney function is severely compromised or failed in Stage 5 (Kidney Failure) (eGFR <15>

Monitoring CKD Progression and Treatment

Tracking the course of CKD and directing treatment choices need routine monitoring of kidney function tests. The pace of loss in kidney function can be determined with great accuracy by monitoring changes in urine protein levels, eGFR, and creatinine over time. Through lifestyle changes, medicine, and, in more severe cases, renal replacement therapy (dialysis or kidney transplantation), treatment techniques for chronic kidney disease (CKD) seek to decrease the illness's course, manage its consequences, and preserve kidney function.

Conclusion

To sum up, renal function tests are essential diagnostic and surveillance instruments for chronic kidney disease (CKD). Based on kidney function measurements, these tests aid in the staging of chronic kidney disease (CKD), enabling individualized treatment plans to impede the illness's advancement and enhance patient outcomes. The key to maintaining kidney function and improving general health in those with chronic kidney disease (CKD) is early detection and routine monitoring of the condition using kidney function testing. For those with CKD, routine follow-up appointments with medical professionals are advised in order to assess kidney health and modify treatment plans as necessary.

Renal function tests must be included in regular health screenings in order to diagnose chronic renal disease early and treat it effectively. People can safeguard their kidney health and general well-being by being proactive and learning the role that kidney function tests play in the diagnosis and monitoring of chronic kidney disease (CKD).

Read FAQs


A. Common kidney function tests include serum creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio (ACR), and urine protein test.

A. Kidney function tests measure levels of substances like creatinine and urea in the blood and proteins in urine. Abnormal levels indicate kidney damage and help stage CKD.

A. The estimated glomerular filtration rate (eGFR) reflects the kidneys' filtering capacity. Lower eGFR values indicate reduced kidney function, a hallmark of Chronic Kidney Disease (CKD).

Read Blog

Heart Related Health Issues: Early Warning Signs You Should Not Ignore

Heart related health issues remain one of the leading causes of illness and death worldwide. Despite advancements in medical care, many heart conditions are diagnosed late because early symptoms are subtle, misunderstood or ignored. Understanding early warning signs of heart related health issues is crucial, as timely action can prevent life-threatening events such as heart attacks and strokes.

Public health data consistently shows that most cardiovascular events are preceded by warning signals that appear weeks, months or even years earlier. Recognising these signs allows for early intervention and better long-term outcomes.

 

What Are Heart Related Health Issues?

Heart related health issues include conditions that affect:

  • the heart muscle
     

  • coronary arteries
     

  • heart valves
     

  • electrical system of the heart
     

Common conditions include coronary artery disease, heart failure, arrhythmias and hypertension-related heart damage.

 

Why Heart Problems Often Go Unnoticed

Heart disease is often called a “silent killer” because:

  • symptoms develop gradually
     

  • early signs are mild
     

  • discomfort is mistaken for fatigue or indigestion
     

  • people delay medical evaluation
     

Unfortunately, waiting for severe pain or emergencies increases risk.

 

Early Warning Signs of Heart Related Health Issues

Chest Discomfort

Chest pain or discomfort is the most recognised warning sign, but it does not always feel severe.

It may present as:

  • pressure
     

  • tightness
     

  • heaviness
     

  • burning sensation
     

Chest discomfort may come and go and worsen with exertion.

 

Breathlessness

Shortness of breath during routine activities or at rest may indicate:

  • reduced heart pumping capacity
     

  • fluid buildup in lungs
     

Breathlessness is often an early sign of heart failure or coronary disease.

 

Unusual Fatigue

Persistent, unexplained fatigue can signal reduced blood supply to the body.

People may notice:

  • exhaustion after minimal activity
     

  • reduced stamina
     

  • prolonged recovery after exertion
     

Fatigue is frequently overlooked as stress or ageing.

 

Palpitations or Irregular Heartbeat

Feeling the heart race, flutter or skip beats may indicate rhythm disturbances.

Symptoms include:

  • rapid heartbeat
     

  • pounding sensation
     

  • irregular pulse
     

Some arrhythmias increase stroke risk if untreated.

 

Dizziness or Lightheadedness

Reduced blood flow to the brain can cause:

  • dizziness
     

  • fainting spells
     

  • imbalance
     

These symptoms may signal heart rhythm or blood pressure issues.

 

Swelling in Legs or Ankles

Fluid retention in lower limbs suggests:

  • weakened heart function
     

  • poor circulation
     

Swelling often worsens by evening and improves overnight.

 

Pain in Other Areas

Heart-related pain may radiate to:

  • left arm
     

  • neck
     

  • jaw
     

  • back
     

  • upper abdomen
     

This atypical pain is common and frequently misdiagnosed.

 

Symptoms That Are More Common in Women

Women may experience:

  • nausea
     

  • jaw pain
     

  • back pain
     

  • extreme fatigue
     

  • shortness of breath without chest pain
     

These non-classic symptoms often delay diagnosis.

 

Risk Factors for Heart Related Health Issues

Major risk factors include:

  • high blood pressure
     

  • diabetes
     

  • high cholesterol
     

  • smoking
     

  • obesity
     

  • sedentary lifestyle
     

  • chronic stress
     

  • family history
     

Risk increases when multiple factors coexist.

 

Why Early Detection Is Critical

Early diagnosis:

  • prevents heart attacks
     

  • reduces heart muscle damage
     

  • lowers hospitalisation risk
     

  • improves quality of life
     

Most heart conditions are manageable when detected early.

 

How Heart Problems Are Diagnosed

Evaluation may involve:

  • blood pressure measurement
     

  • blood tests
     

  • electrocardiogram (ECG)
     

  • imaging studies
     

  • stress testing
     

Tests are chosen based on symptoms and risk profile.

 

Treatment and Management

Medical Management

Depending on the condition:

  • medications
     

  • lifestyle changes
     

  • monitoring
     

Early treatment slows disease progression.

 

Lifestyle Modification

Lifestyle plays a major role in heart health:

  • balanced diet
     

  • regular physical activity
     

  • stress management
     

  • adequate sleep
     

  • smoking cessation
     

Lifestyle changes significantly reduce risk.

 

Preventive Measures for Heart Health

  • regular health checkups
     

  • blood pressure and sugar monitoring
     

  • cholesterol screening
     

  • physical activity
     

  • heart-healthy diet
     

Prevention is the most effective strategy against heart disease.

 

When to Seek Immediate Medical Help

Seek urgent care if:

  • chest pain is severe or persistent
     

  • breathlessness occurs suddenly
     

  • fainting happens
     

  • pain radiates to arm or jaw
     

Prompt action saves lives.

 

Long-Term Impact of Ignoring Warning Signs

Ignoring early symptoms may lead to:

  • heart attack
     

  • stroke
     

  • heart failure
     

  • permanent heart damage
     

  • sudden cardiac events
     

Delayed care increases mortality risk.

 

Conclusion

Heart related health issues rarely appear suddenly without warning. The body often sends early signals such as chest discomfort, fatigue, breathlessness and palpitations long before emergencies occur. Recognising these early warning signs and seeking timely medical evaluation can prevent serious complications and save lives. Heart health requires awareness, proactive care and early action—because when it comes to the heart, ignoring symptoms is a risk no one should take.

 

References

  • Indian Council of Medical Research (ICMR) – Cardiovascular Disease Report

  •  World Health Organization (WHO) – Cardiovascular Health Guidelines

  • National Heart Institute – Early Signs of Heart Disease

  • Lancet – Global Burden of Cardiovascular Disease Studies

  • Indian Journal of Cardiology – Heart Disease Detection and Preventio

  •  Statista – Heart Disease Trends and Risk Factors

See all

Live Doctor consultation
Live Doctor Chat

Download Our App & Get Consultation from anywhere.

App Download
call icon for mobile number calling and whatsapp at secondmedic