Call
+918447748545

Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

Read Blog

Flexible Work Schedules with Telehealth Support: A Smarter Approach to Employee Wellbeing

The modern workplace is undergoing a significant transformation. Rigid office hours and traditional healthcare access models are giving way to flexible work schedules and digital health solutions. One of the most impactful combinations emerging in corporate wellness is flexible work schedules with telehealth support.

This integrated approach addresses two critical challenges faced by today’s workforce: work-life imbalance and delayed healthcare access.

Why Workplace Health Models Need to Change

According to NITI Aayog and EY-FICCI workforce reports, Indian employees face rising levels of:

work-related stress
lifestyle diseases
burnout
absenteeism

Long working hours, commuting stress and limited time for medical visits worsen health outcomes. Flexible work arrangements and telehealth support directly address these gaps.

What Are Flexible Work Schedules?

Flexible work schedules allow employees to:

adjust start and end times
work remotely or in hybrid formats
manage personal commitments alongside work

Flexibility empowers employees to align work with their physical and mental health needs.

Understanding Telehealth Support

Telehealth uses digital platforms to deliver healthcare services such as:

online doctor consultations
follow-up care
preventive health advice
mental health support

It eliminates geographical and time barriers to healthcare.

Why Combining Flexibility with Telehealth Works

Individually, flexibility and telehealth are beneficial. Together, they create a powerful wellness ecosystem.

This combination allows employees to:

consult doctors without taking leave
manage chronic conditions proactively
address early symptoms promptly
reduce healthcare delays

Health Benefits for Employees

Reduced Stress and Burnout

Flexible schedules reduce time pressure, while telehealth removes healthcare-related anxiety.

Improved Access to Preventive Care

Employees are more likely to seek early consultations when care is convenient.

Better Management of Chronic Conditions

Conditions like hypertension, diabetes and thyroid disorders require regular follow-up, which telehealth supports efficiently.

Enhanced Mental Wellbeing

Tele-mental health services enable confidential and timely support.

Improved Work-Life Balance

Employees can prioritise health without compromising job responsibilities.

Productivity Benefits for Employers

Reduced Absenteeism

Quick access to care reduces prolonged sick leave.

Improved Employee Engagement

Health-supported employees show higher motivation and loyalty.

Lower Healthcare Costs

Preventive care reduces long-term medical claims.

Strong Employer Branding

Wellness-focused policies attract and retain talent.

Evidence Supporting Flexible Work and Telehealth

According to WHO and Lancet workplace health studies:

flexible work reduces stress-related disorders
telehealth improves healthcare utilisation
preventive care lowers chronic disease burden

Indian corporate data mirrors these findings, especially in hybrid work environments.

Role in Preventive Healthcare

Preventive healthcare focuses on early risk identification and lifestyle management.

Flexible schedules with telehealth support:

encourage routine checkups
support ongoing health monitoring
enable early intervention

This aligns with India’s preventive healthcare priorities outlined by NITI Aayog.

Addressing Common Concerns

Productivity Loss Myth

Multiple studies show flexible work improves output rather than reducing it.

Quality of Telehealth

Telehealth is effective for most primary care and follow-up needs.

Data Security

Modern telehealth platforms follow strict privacy and data protection standards.

Ideal Use Cases in the Workplace

This model is particularly effective for:

IT and corporate offices
remote and hybrid teams
organisations with distributed workforce
high-stress work environments

Implementation Best Practices

To maximise impact:

set clear flexibility guidelines
integrate telehealth access into HR benefits
promote preventive consultations
track wellness metrics

Leadership support is key to adoption.

Long-Term Organisational Impact

Organisations adopting this model report:

improved employee health indicators
reduced burnout
stronger workplace culture
sustainable productivity gains

Wellbeing becomes a strategic advantage.

Conclusion

Flexible work schedules with telehealth support represent the future of employee wellbeing. By removing barriers to healthcare access and allowing employees control over their work routines, this approach promotes preventive care, reduces stress and enhances productivity. As workplaces evolve, integrating flexibility with digital health support is not just an employee benefit—it is a strategic investment in long-term organisational health and resilience.

References

World Health Organization (WHO) – Workplace Health Promotion Framework
Indian Council of Medical Research (ICMR) – Lifestyle Disease and Workforce Health Studies
NITI Aayog – Digital Health and Workplace Wellness Reports
Lancet – Telehealth and Workforce Productivity Research
EY-FICCI – Corporate Wellness and Future of Work Reports
Statista – Telehealth Adoption and Workforce Trends

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.