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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Replace Junk with Subscription Snack Packs: A Practical Approach to Preventive Nutrition in India

India is witnessing a growing shift toward healthier eating habits, yet junk food consumption continues to rise across all age groups. According to ICMR and NFHS-5 data, high-calorie packaged snacks, sugary beverages and deep-fried foods contribute significantly to obesity, diabetes and cardiovascular risk. Replacing these items with nutritious snack alternatives is one of the simplest yet most effective steps toward preventive wellness.

Subscription snack packs offer a structured, convenient and affordable way to transition from unhealthy snacking to balanced nutrition. SecondMedic promotes this approach as part of a broader preventive health ecosystem that focuses on long-term behavioural change rather than temporary diets.

Why Indians are Choosing Healthy Snack Subscriptions

1. Convenience in fast-paced lifestyles

Urban and semi-urban households often depend on quick, accessible snacks to keep up with busy schedules. Healthy subscription packs bring pre-portioned nutrition directly to the doorstep.

2. Rising health concerns

India now ranks among the world’s highest in:

Diabetes prevalence
Childhood obesity
Hypertension
High cholesterol

Replacing junk food is essential for reducing these long-term risks.

3. Growing awareness of clean eating

People are moving toward:

Low-sugar
Low-sodium
High-fibre
High-protein
Non-fried
snack alternatives.

4. Cost-effectiveness

Contrary to belief, balanced snack packs cost less than repeated purchases of unhealthy packaged foods.

What Makes Subscription Snack Packs Healthier?

Healthy snack packs are curated for balanced nutrition:

• Nuts and seeds

Rich in healthy fats, fibre and minerals.

• Millet-based snacks

Low GI, nutrient-dense and suitable for diabetics.

• Dried fruits

Provide natural sweetness without refined sugar.

• Roasted chana and legumes

Excellent plant-based protein sources.

• Low-sugar bars

Made from oats, dates, nuts and seeds.

• Whole-grain crackers

Better than refined flour biscuits.

• Herbal teas

Support digestion and relaxation.

These snacks reduce cravings while supporting metabolic health.

Why Junk Food Needs Replacement

• High in trans fats

Linked to heart disease and inflammation.

• Excess sugar

Promotes insulin resistance, weight gain and metabolic syndrome.

• Refined flour

Lacks fibre and elevates glucose rapidly.

• Additives & preservatives

May contribute to long-term digestive and metabolic issues.

• Instant cravings

Junk foods trigger overeating by stimulating dopamine pathways.

Replacing them with healthier options breaks this cycle.

How Subscription Snack Packs Support Preventive Healthcare

1. Portion control

Pre-measured servings reduce the risk of overeating.

2. Balanced nutrition

Snack packs provide fibre, healthy fats and micronutrients missing from typical Indian diets.

3. Reduced decision fatigue

Users do not have to search for healthy options daily.

4. Behavioural consistency

Weekly or monthly packs promote long-term habit formation.

5. Support for chronic disease management

Especially helpful for:

Diabetes
PCOS
Thyroid issues
Heart disease

SecondMedic integrates snack guidance into dietitian consultations and AI-driven nutrition analysis.

The Role of AI Health Guide in Smarter Snacking

SecondMedic’s AI Health Guide provides:

• Calorie and nutrient insights

Evaluates daily intake based on user habits.

• Snack recommendations

Based on medical conditions, preferences and goals.

• Craving pattern analysis

Identifies triggers for unhealthy eating.

• Personalised preventive plans

Aligns snacking habits with heart, gut and metabolic health.

This makes snack substitution easier and more sustainable.

How to Transition from Junk Food to Healthy Snack Packs

Step 1: Identify your biggest cravings

Sugary, salty, crunchy or fried?

Step 2: Find healthier alternatives

For example:

Replace chips ? roasted makhana
Replace sweets ? dates + nuts
Replace biscuits ? whole-grain crackers

Step 3: Use subscription packs for structure

Pre-curated boxes guide behaviour change.

Step 4: Track progress

Energy levels improve within 2-4 weeks.

Step 5: Build long-term habits

Consistency leads to metabolic improvement.

Conclusion

Replacing junk food with subscription snack packs is an effective and convenient step toward preventive wellness in India. By combining healthier ingredients, balanced nutrition and consistent delivery, subscription packs help individuals make better choices daily. With expert guidance and AI-driven insights from SecondMedic, these changes become sustainable, personalised and impactful for long-term health.

References

• ICMR - Dietary Patterns & Junk Food Consumption Study
• NFHS-5 - Nutrition Deficiencies & Lifestyle Data India
• NITI Aayog - Preventive Health & Nutrition Strategy
• WHO - Healthy Diet & Non-Communicable Disease Guidelines
• Lancet - Consumption Patterns & Cardiometabolic Risk
• Statista India - Healthy Snacking Trends
• EY-FICCI - Consumer Behaviour Toward Preventive Health

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