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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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KEYWORD: Employee Wall of Fame – Celebrate uniqueness

In today’s competitive and fast-paced work environment, employee recognition plays a vital role in building a positive and productive workplace culture. While salary and benefits are important, appreciation and acknowledgment often have a deeper and longer-lasting impact on motivation.

An Employee Wall of Fame is a powerful yet simple initiative that celebrates individual contributions, highlights achievements and reinforces a culture of appreciation.

What Is an Employee Wall of Fame?

An Employee Wall of Fame is a recognition platform — physical or digital — that showcases employees who have demonstrated exceptional performance, creativity, teamwork or leadership.

It may include:

Employee photographs
Achievement descriptions
Monthly or quarterly awards
Customer appreciation highlights
Team milestones

This visible recognition fosters pride and belonging.

Why Celebrating Uniqueness Matters

Every employee brings distinct skills, experiences and perspectives to the organization. Recognizing uniqueness:

Encourages diversity
Builds confidence
Promotes innovation
Strengthens team cohesion

Appreciation creates an inclusive culture where everyone feels valued.

Benefits of an Employee Wall of Fame

1. Boosts Employee Morale

Public recognition reinforces positive behavior and motivates others to perform better.

Employees feel acknowledged for their hard work.

2. Enhances Productivity

When employees know their efforts are recognized, they are more likely to:

Stay engaged
Take initiative
Maintain consistent performance

Motivation translates into measurable productivity gains.

3. Strengthens Workplace Culture

Recognition fosters:

Respect
Team spirit
Healthy competition

A positive environment encourages long-term retention.

4. Encourages Continuous Improvement

Highlighting achievements sets performance benchmarks.

Employees strive to improve skills and meet high standards.

5. Improves Employee Retention

Feeling valued reduces turnover.

Recognition strengthens emotional connection with the organization.

Types of Employee Wall of Fame Models

Physical Recognition Board

Placed in office reception or common area.

Ideal for on-site teams.

Digital Wall of Fame

Hosted on company intranet or website.

Suitable for remote or hybrid teams.

Themed Recognition

Examples include:

Innovator of the Month
Team Player Award
Customer Champion
Wellness Ambassador

This allows diverse achievements to be celebrated.

How to Implement an Effective Wall of Fame

Define Clear Criteria

Establish transparent guidelines for selection.

Encourage Peer Nominations

Allow employees to nominate colleagues.

This increases participation and fairness.

Rotate Recognition Regularly

Monthly or quarterly updates maintain enthusiasm.

Share Stories

Include short narratives describing contributions.

Stories inspire others and personalize achievements.

Combine with Rewards

Certificates, small gifts or appreciation emails enhance impact.

Employee Recognition in the Indian Workplace

With evolving workplace dynamics in India, organizations are focusing more on employee engagement and cultural development.

Recognition programs like Employee Wall of Fame help companies build stronger employer branding and create motivating environments.

Such initiatives are particularly effective in fast-growing sectors such as healthcare, IT and startups.

Addressing Common Challenges

Avoid Bias

Use structured evaluation criteria.

Maintain Consistency

Ensure regular updates to sustain credibility.

Encourage Inclusivity

Recognize diverse roles, not just top performers.

Long-Term Impact on Organizations

Organizations that celebrate employee uniqueness often experience:

Higher engagement levels
Better teamwork
Increased innovation
Stronger organizational loyalty

Recognition transforms workplace dynamics positively.

Integrating Wall of Fame with Wellness Culture

Companies can align recognition with health and wellbeing initiatives, such as:

Fitness achievements
Community volunteering
Mental health advocacy

Celebrating holistic contributions promotes balanced development.

Conclusion

An Employee Wall of Fame is more than a decorative display — it is a strategic recognition tool that celebrates uniqueness and strengthens workplace culture.

By acknowledging achievements openly and consistently, organizations foster motivation, engagement and loyalty.

In an era where talent retention and employee satisfaction are critical, simple appreciation initiatives can create lasting impact.

Celebrating individuality is not just good for morale — it is essential for building resilient and high-performing teams.

Recognition inspires excellence, and excellence drives success.

References

World Health Organization – Healthy Workplace Framework
Harvard Business Review – Employee Recognition Research
Indian Journal of Occupational Health – Workplace Engagement Studies
Society for Human Resource Management (SHRM) – Recognition Reports
NITI Aayog – Workplace Wellness Strategies

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