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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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How Weekly Onsite Yoga Benefits Corporate Wellness: A Preventive Approach to Workplace Health

Corporate wellness programs are evolving rapidly. Traditional initiatives such as annual health checkups and gym memberships are no longer sufficient to address modern workplace health challenges. Rising stress levels, sedentary routines and burnout have pushed organisations to adopt preventive, sustainable wellness strategies. One of the most effective among these is weekly onsite yoga.

Understanding how onsite yoga weekly benefits corporate wellness highlights why this ancient practice has become a modern workplace necessity. Yoga addresses both physical and mental health, making it uniquely suited for today’s high-pressure corporate environments.

Why Corporate Wellness Needs Preventive Solutions

According to the Indian Council of Medical Research (ICMR) and workplace health reports, lifestyle-related disorders such as hypertension, diabetes, obesity and mental health conditions are increasingly affecting working professionals.

Key workplace health challenges include:

prolonged sitting
poor posture
chronic stress
sleep disturbances
reduced physical activity

Preventive interventions are essential to reverse these trends before they result in chronic disease and productivity loss.

What Is Weekly Onsite Yoga?

Weekly onsite yoga involves structured yoga sessions conducted at the workplace by trained instructors. These sessions typically include:

stretching and mobility exercises
breathing techniques
simple yoga postures
relaxation and mindfulness practices

Sessions are designed to be inclusive, requiring no prior yoga experience.

Why Weekly Frequency Matters

Consistency is the foundation of wellness.

Weekly yoga sessions:

reinforce healthy habits
prevent accumulation of stress
support gradual physical improvement
encourage long-term participation

Unlike one-time workshops, weekly programs deliver sustained impact.

Physical Health Benefits of Onsite Yoga

Reduces Musculoskeletal Problems

Desk-based work often leads to back pain, neck stiffness and joint discomfort. Yoga improves:

posture
flexibility
muscle strength

This reduces work-related musculoskeletal disorders.

Improves Cardiovascular and Metabolic Health

Regular yoga practice supports:

blood pressure regulation
improved circulation
better glucose control

WHO recognises yoga and similar mind-body practices as beneficial for lifestyle disease prevention.

Enhances Energy Levels

Yoga improves oxygenation and circulation, reducing fatigue and mid-day energy crashes.

Mental Health Benefits in the Workplace

Reduces Stress and Burnout

Yoga lowers cortisol levels and activates the parasympathetic nervous system, promoting relaxation.

This helps employees:

manage deadlines calmly
recover from mental fatigue
reduce anxiety

Improves Focus and Cognitive Performance

Breathing and mindfulness practices improve:

attention span
mental clarity
decision-making

Better focus directly translates into improved productivity.

Supports Emotional Wellbeing

Regular yoga enhances emotional regulation, reducing irritability and improving workplace relationships.

Impact on Productivity and Performance

Healthy employees perform better.

Weekly onsite yoga contributes to:

reduced absenteeism
fewer stress-related sick days
improved work engagement
sustained productivity

EY-FICCI corporate wellness studies show that preventive wellness programs deliver measurable performance benefits.

Role in Building a Wellness-Oriented Culture

Onsite yoga sends a strong message that employee wellbeing is a priority.

It helps organisations:

foster trust and engagement
encourage work-life balance
create a supportive environment

Wellness culture improves retention and employer branding.

Inclusivity and Accessibility

One of yoga’s biggest strengths is adaptability.

Onsite yoga:

suits all age groups
accommodates different fitness levels
requires minimal equipment
can be modified for health conditions

This inclusivity ensures broad participation.

Cost-Effectiveness and ROI

Compared to advanced medical interventions, onsite yoga is:

low-cost
scalable
preventive rather than reactive

By reducing long-term healthcare costs, yoga delivers high return on investment for employers.

Yoga as Part of Preventive Healthcare

Preventive healthcare focuses on reducing risk factors before disease develops.

Weekly onsite yoga supports prevention by:

lowering stress-related disease risk
improving metabolic health
encouraging active lifestyles
supporting mental resilience

NITI Aayog recognises workplace wellness as a key lever for national health improvement.

Integration with Corporate Wellness Programs

Onsite yoga works best when integrated with:

preventive health checkups
stress management initiatives
nutrition education
digital health tracking

Integrated programs deliver stronger outcomes than isolated activities.

Overcoming Common Barriers

Some organisations hesitate due to:

time constraints
perceived lack of interest
space concerns

However, short, well-structured sessions (30–45 minutes) overcome these challenges effectively.

Long-Term Impact on Organisations

Organisations that adopt weekly onsite yoga observe:

healthier workforce
reduced burnout
improved morale
better long-term healthcare outcomes

Lancet workplace health studies show that consistent mind-body interventions yield benefits within 6–12 months.

Conclusion

Understanding how onsite yoga weekly benefits corporate wellness reveals why it is more than a fitness activity—it is a preventive health strategy. By addressing physical strain, mental stress and lifestyle risks, weekly onsite yoga supports healthier employees, stronger productivity and sustainable wellness culture. In today’s demanding corporate environment, investing in regular yoga sessions is an investment in long-term organisational resilience and success.

References

ICMR – Workplace Health and Lifestyle Disease Reports
National Family Health Survey (NFHS-5) – Adult Health and Stress Indicators
NITI Aayog – Preventive Healthcare and Workplace Wellness Strategy
WHO – Physical Activity, Yoga and Mental Health Guideline
Lancet – Mind-Body Interventions and Workplace Health Outcomes
EY-FICCI – Corporate Wellness and Productivity Report
Statista – Corporate Wellness Program Trends India

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