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Published on: Apr 04, 2020
2 minute read
By: Raj Dwivedi

Problems With Detecting The Novel Coronavirus (COVID-19) (1)

The Novel Coronavirus Disease has been in the public eye for almost two months now, and a lot has been happening behind the scenes to understand this new outbreak. Several organizations have been working together with the World Health Organization and Officials from China to understand the symptoms and how the virus causes the disease, track the number of people infected by the virus and put in place public health measures to adequately mitigate the potential dangers this disease can bring with it. In this post we will discuss the new updates to the Coronavirus Disease 2019 (COVID-19).

IDENTIFYING COVID-19

As of 17 February, there have been 70, 365 confirmed cases of COVID-19 in China, with 1772 deaths, which gives it an estimated fatality rate of 2.5%. Now whilst these are official figures, the actual estimate may differ from this. This is because the areas that have been heavily affected especially the Hubei region, have had shortages of coronavirus testing kits, with demands far outstripping supply. Testing is required to not only identify patients for treatment but also for isolation and quarantine. This is a key step in preventing the rapid spread of disease amongst the population. Understanding the spread of a new disease also helps scientists create accurate disease models that can determine the infectivity, morbidity and mortality of COVID-19, and predict where the infection may strike next. The government authorities can use this information to prepare the surrounding regions, and ensure the impact of the disease is lessened.

Current testing requires swabs to be taken from the patients mouth and throat. This sample is then sent to laboratories, where the viral DNA is replicated in order to identify whether this DNA is from the coronavirus. Unfortunately, this is expensive, uses lots of reagents and can take two days. Even with laboratories working round the clock, running 6,000 tests a day, the workload is outstripping the health departments capacity. This leaves a large population of the Hubei Province with symptoms suggestive of COVID-19 but with no way to formally diagnose the disease. There may be a significant under-reporting of cases simply because capacity does not exist to test everyone, and the disease burden may be considerably higher.

INNOVATION IN RESPONSE

In response to this doctors have started using CT scans to identify potentially infected patients. CT scans are a quick, non-invasive and readily available. By looking for lesions and signs of pneumonia in the patients lungs. Whilst this negates the need for testing strips, lesions are a fairly late sign of COVID-19, and so this method is not suitable for those who have recently been infected or have not yet shown these symptoms. In the Hubei Province however, with the drastic shortage of testing kits, clinical and radiological diagnosis is now being used to increase the rate of detection.

Manufacturers are also struggling to increase output of testing kits and reagents to match this demand, and the race is on to develop new rapid testing kits. Beijing has approved seven Biopharmaceutical companies to push forward with fast track development of testing kits. Liferiver, a Shanghai based biotech company, took just 20 days from development of its kit to launch. This process normally takes 3 years. China’s Nankai University announced on Monday a breakthrough in developing a rapid test kit that can identify infection among suspected patients within 15 minutes.

And it’s not just Chinese companies — a Singapore based biotech company has announced a portable kit that can detect the novel coronavirus as well as similar viruses responsible for MERS and SARS in a single 2 hour test. These innovations represent a massive step forward in identifying infected patients early in order to provide them the necessary treatment, and in accurately tracking the spread of the disease.

www.secondmedic.com

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Monkeypox Virus Symptoms: Early Signs, Disease Progression, and When to Seek Care

Monkeypox, now commonly referred to as mpox, is a viral infection that has gained global attention due to outbreaks beyond traditionally affected regions. Understanding monkeypox virus symptoms is essential for early detection, timely isolation and prevention of further spread.

According to the World Health Organization and Indian public health authorities, awareness of symptom patterns plays a critical role in controlling outbreaks and protecting vulnerable populations.

What Is the Monkeypox Virus?

Monkeypox is caused by the monkeypox virus, a member of the Orthopoxvirus family, which also includes smallpox. While generally less severe than smallpox, monkeypox can still cause significant illness and discomfort.

The virus spreads primarily through close physical contact.

Incubation Period of Monkeypox

After exposure, symptoms typically appear within:

5 to 21 days
most commonly 6 to 13 days

Individuals may feel well during this period but can become infectious once symptoms begin.

Early Monkeypox Virus Symptoms

Fever

Fever is usually the first symptom and may be:

sudden in onset
moderate to high grade
accompanied by chills

Fever signals the start of systemic infection.

Headache and Body Aches

Patients often experience:

severe headache
muscle aches
back pain

These symptoms resemble many viral illnesses.

Fatigue and Weakness

Marked tiredness and low energy levels are common and may limit daily activities.

Swollen Lymph Nodes

Swollen lymph nodes are a distinguishing feature of monkeypox.

Common sites include:

neck
armpits
groin

This helps differentiate monkeypox from chickenpox or smallpox.

Development of Monkeypox Rash

The skin rash usually appears:

1 to 3 days after fever onset

It may begin on the face or genital area and spread to other parts of the body.

Stages of Monkeypox Rash

The rash progresses through well-defined stages:

Macules

Flat red spots on the skin.

Papules

Raised, firm bumps.

Vesicles

Fluid-filled blisters.

Pustules

Pus-filled lesions that are painful.

Scabs

Lesions crust over and eventually fall off.

Complete healing occurs once scabs detach.

Distribution of Rash

Rash commonly affects:

face
hands and feet
mouth
genital and anal areas

The number of lesions can vary widely.

Pain and Discomfort

Rash lesions may be:

painful
itchy during healing

Pain severity differs between individuals.

Other Possible Symptoms

Additional symptoms may include:

sore throat
cough
nasal congestion

These reflect upper respiratory involvement.

Duration of Illness

Monkeypox symptoms typically last:

2 to 4 weeks

Recovery occurs gradually as lesions heal.

Who Is at Higher Risk of Severe Illness?

Higher risk groups include:

children
pregnant women
individuals with weakened immunity
people with chronic illness

Early care is crucial in these groups.

Complications of Monkeypox

Though uncommon, complications may include:

secondary bacterial skin infections
dehydration
pneumonia
eye involvement

Prompt medical guidance reduces risk.

How Monkeypox Is Transmitted

Transmission occurs through:

direct skin-to-skin contact
contact with lesions or bodily fluids
respiratory droplets during close contact
contaminated clothing or bedding

Understanding transmission helps prevent spread.

When to Seek Medical Care

Seek medical evaluation if:

fever is followed by rash
lymph nodes become swollen
rash appears in genital or facial areas

Early diagnosis supports isolation and care.

Diagnosis and Testing

Diagnosis may involve:

clinical examination
laboratory testing of lesion samples

Public health authorities guide testing protocols.

Prevention and Control Measures

Preventive steps include:

avoiding close contact with infected individuals
maintaining good hand hygiene
isolating during illness
following public health guidance

Vaccination may be recommended for high-risk groups.

Role of Public Awareness

Awareness of symptoms:

enables early detection
reduces stigma
supports timely care

WHO emphasises community education in outbreak control.

Conclusion

Monkeypox virus symptoms typically begin with fever, body aches and swollen lymph nodes, followed by a characteristic rash that progresses through defined stages. While most cases are self-limiting, early recognition, medical evaluation and isolation are essential to prevent complications and reduce transmission. Staying informed and acting promptly protects both individual and public health.

References

World Health Organization (WHO) – Mpox (Monkeypox) Clinical and Public Health Guidance
Indian Council of Medical Research (ICMR) – Emerging Viral Infections Reports
National Centre for Disease Control (NCDC), India – Monkeypox Advisories
Lancet – Clinical Features and Outcomes of Mpox
NITI Aayog – Public Health Preparedness and Infectious Disease Control

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