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Published on: Apr 04, 2020
2 minute read
By: Raj Dwivedi

Problems With Detecting The Novel Coronavirus (COVID-19) (1)

The Novel Coronavirus Disease has been in the public eye for almost two months now, and a lot has been happening behind the scenes to understand this new outbreak. Several organizations have been working together with the World Health Organization and Officials from China to understand the symptoms and how the virus causes the disease, track the number of people infected by the virus and put in place public health measures to adequately mitigate the potential dangers this disease can bring with it. In this post we will discuss the new updates to the Coronavirus Disease 2019 (COVID-19).

IDENTIFYING COVID-19

As of 17 February, there have been 70, 365 confirmed cases of COVID-19 in China, with 1772 deaths, which gives it an estimated fatality rate of 2.5%. Now whilst these are official figures, the actual estimate may differ from this. This is because the areas that have been heavily affected especially the Hubei region, have had shortages of coronavirus testing kits, with demands far outstripping supply. Testing is required to not only identify patients for treatment but also for isolation and quarantine. This is a key step in preventing the rapid spread of disease amongst the population. Understanding the spread of a new disease also helps scientists create accurate disease models that can determine the infectivity, morbidity and mortality of COVID-19, and predict where the infection may strike next. The government authorities can use this information to prepare the surrounding regions, and ensure the impact of the disease is lessened.

Current testing requires swabs to be taken from the patients mouth and throat. This sample is then sent to laboratories, where the viral DNA is replicated in order to identify whether this DNA is from the coronavirus. Unfortunately, this is expensive, uses lots of reagents and can take two days. Even with laboratories working round the clock, running 6,000 tests a day, the workload is outstripping the health departments capacity. This leaves a large population of the Hubei Province with symptoms suggestive of COVID-19 but with no way to formally diagnose the disease. There may be a significant under-reporting of cases simply because capacity does not exist to test everyone, and the disease burden may be considerably higher.

INNOVATION IN RESPONSE

In response to this doctors have started using CT scans to identify potentially infected patients. CT scans are a quick, non-invasive and readily available. By looking for lesions and signs of pneumonia in the patients lungs. Whilst this negates the need for testing strips, lesions are a fairly late sign of COVID-19, and so this method is not suitable for those who have recently been infected or have not yet shown these symptoms. In the Hubei Province however, with the drastic shortage of testing kits, clinical and radiological diagnosis is now being used to increase the rate of detection.

Manufacturers are also struggling to increase output of testing kits and reagents to match this demand, and the race is on to develop new rapid testing kits. Beijing has approved seven Biopharmaceutical companies to push forward with fast track development of testing kits. Liferiver, a Shanghai based biotech company, took just 20 days from development of its kit to launch. This process normally takes 3 years. China’s Nankai University announced on Monday a breakthrough in developing a rapid test kit that can identify infection among suspected patients within 15 minutes.

And it’s not just Chinese companies — a Singapore based biotech company has announced a portable kit that can detect the novel coronavirus as well as similar viruses responsible for MERS and SARS in a single 2 hour test. These innovations represent a massive step forward in identifying infected patients early in order to provide them the necessary treatment, and in accurately tracking the spread of the disease.

www.secondmedic.com

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How Inflammation Affects Overall Health: Understanding the Hidden Risks

Inflammation is often misunderstood. While it is a vital protective response of the immune system, persistent or chronic inflammation can quietly damage tissues and increase the risk of serious diseases. Understanding how inflammation affects overall health is crucial in preventing long-term complications and maintaining optimal wellbeing.

According to the World Health Organization and global medical research published in Lancet, chronic inflammation is linked to a wide range of non-communicable diseases, including heart disease, diabetes and autoimmune disorders.

What Is Inflammation?

Inflammation is the body’s natural response to:

infection
injury
toxins
stress

It activates immune cells to eliminate harmful stimuli and promote healing.

There are two main types:

Acute Inflammation

Short-term and protective.
Examples include swelling after injury or fever during infection.

Chronic Inflammation

Long-term, low-grade inflammation that persists even without injury.

Chronic inflammation is harmful.

How Chronic Inflammation Develops

Persistent inflammation can result from:

unhealthy diet
sedentary lifestyle
obesity
chronic stress
environmental toxins
untreated infections

Modern lifestyle patterns contribute significantly to this condition.

Impact on Heart Health

Inflammation damages blood vessels and promotes plaque formation.

This increases risk of:

heart attack
stroke
hypertension

ICMR data highlights cardiovascular disease as a leading cause of death in India, with inflammation playing a contributing role.

Link Between Inflammation and Diabetes

Chronic inflammation interferes with insulin signalling.

This leads to:

insulin resistance
elevated blood sugar
metabolic syndrome

NFHS-5 data shows rising diabetes prevalence, partly linked to inflammatory lifestyle factors.

Effect on Joint and Muscle Health

Inflammatory processes contribute to:

arthritis
joint stiffness
muscle pain

Autoimmune diseases often involve chronic inflammation.

Gut Health and Inflammation

The gut plays a central role in immune regulation.

Poor diet and stress disrupt gut balance, triggering:

inflammatory bowel conditions
digestive discomfort
nutrient malabsorption

Gut inflammation impacts systemic health.

Brain Health and Inflammation

Emerging research suggests chronic inflammation affects:

memory
mood
cognitive performance

Inflammatory markers are associated with depression and neurodegenerative disorders.

Chronic Fatigue and Inflammatory Stress

Persistent inflammation causes:

ongoing fatigue
reduced stamina
sleep disturbances

The immune system remains in constant activation mode.

Role in Autoimmune Disorders

Autoimmune diseases occur when the immune system mistakenly attacks healthy tissues.

Chronic inflammation is central to conditions such as:

rheumatoid arthritis
lupus
inflammatory bowel disease

Signs of Chronic Inflammation

Symptoms may include:

unexplained fatigue
persistent joint pain
digestive issues
frequent infections
skin problems

Early detection is important.

Lifestyle Factors That Increase Inflammation

High Sugar Intake

Excess sugar promotes inflammatory pathways.

Processed Foods

Trans fats and additives trigger immune responses.

Sedentary Lifestyle

Lack of exercise reduces anti-inflammatory benefits.

Poor Sleep

Sleep deprivation increases inflammatory markers.

Chronic Stress

Elevated cortisol disrupts immune balance.

Natural Ways to Reduce Inflammation

Anti-Inflammatory Diet

Include:

leafy greens
fruits rich in antioxidants
nuts and seeds
whole grains

Avoid excessive processed foods.

Regular Physical Activity

Exercise lowers inflammatory markers and improves circulation.

Stress Management

Meditation and breathing exercises reduce stress hormones.

Adequate Sleep

7–8 hours of quality sleep supports immune regulation.

Maintain Healthy Weight

Excess abdominal fat produces inflammatory chemicals.

Role of Preventive Health Screening

Regular tests such as:

blood sugar
lipid profile
inflammatory markers

help monitor risk factors early.

Importance of Early Intervention

Unchecked inflammation increases risk of:

cardiovascular disease
metabolic disorders
organ damage

Timely lifestyle changes reverse early inflammatory effects.

Long-Term Health Benefits of Inflammation Control

Reducing inflammation supports:

heart health
stable blood sugar
improved immunity
enhanced cognitive function
reduced pain

Preventive strategies protect long-term wellbeing.

Conclusion

Understanding how inflammation affects overall health reveals its profound impact on the heart, brain, gut and metabolic systems. While acute inflammation protects the body, chronic inflammation silently contributes to major diseases. Fortunately, lifestyle changes such as balanced nutrition, regular exercise, quality sleep and stress management significantly reduce inflammatory burden. Prevention and early monitoring remain the most effective tools for protecting overall health and ensuring long-term vitality.

References

World Health Organization (WHO) – Chronic Disease and Inflammation Reports
Indian Council of Medical Research (ICMR) – Cardiovascular and Metabolic Health Studies
National Family Health Survey (NFHS-5) – Diabetes and Hypertension Data
NITI Aayog – Preventive Healthcare Strategy Reports
Lancet – Inflammation and Chronic Disease Research

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