• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Brain Fog After Viral Infections

Brain Fog After Viral Infections: Why So Many Indians Are Reporting Memory Issues

In recent years, a growing number of Indians have been reporting a strange yet troubling experience after recovering from viral infections – difficulty focusing, forgetfulness, and mental fatigue. This condition, commonly referred to as brain fog, is leaving many people puzzled and anxious about their cognitive health. But what exactly is brain fog? And why does it seem to follow viral infections so often?

Let’s break it down and understand why so many Indians are experiencing memory issues after viral illnesses and what can be done about it.

 

What is Brain Fog?

Brain fog is not a medical diagnosis but a term used to describe a collection of symptoms that affect your ability to think clearly. It can include:

  • Trouble concentrating

  • Forgetfulness

  • Slow thinking

  • Mental fatigue

  • Difficulty multitasking

  • Lack of mental clarity
     

People often describe it as feeling like their brain is “cloudy” or “foggy,” hence the name.

 

Why Does Brain Fog Happen After Viral Infections?

Viruses like COVID-19, influenza, dengue, and even the common cold can impact brain function in subtle but serious ways. Here are a few reasons why brain fog may occur after recovering from a viral infection:

1. Inflammation in the Brain

When your body fights a virus, it produces inflammation as part of the immune response. Sometimes, this inflammation can reach the brain, even if the virus itself doesn’t. This can disrupt normal brain function and cause symptoms of brain fog.

2. Reduced Oxygen Supply

Some viral infections, especially COVID-19, can affect your lungs and reduce the amount of oxygen reaching your brain. A lack of sufficient oxygen can impair brain activity, leading to confusion, fatigue, and forgetfulness.

3. Disrupted Sleep Patterns

Viral illnesses often disturb sleep – either due to fever, congestion, coughing, or stress. Poor sleep quality directly affects brain performance and memory. Long-term sleep disruption can even mimic symptoms of cognitive decline.

4. Post-Viral Fatigue Syndrome

Many people suffer from fatigue for weeks or months after a viral infection. This prolonged tiredness also impacts mental alertness and memory. It’s like your body is trying to heal, but your brain hasn’t caught up yet.

5. Stress and Anxiety

Getting sick, especially during a pandemic, brings emotional stress and anxiety. Financial worries, isolation, and fear of reinfection can all take a toll on mental health and contribute to brain fog.

 

Why Are So Many Indians Affected?

There are several reasons why this issue seems to be widespread in India:

1. High Viral Load in Population

India has seen a high incidence of viral infections in recent years – from waves of COVID-19 to seasonal flu and dengue. With so many people exposed, it’s no surprise that post-viral symptoms like brain fog are being reported on a large scale.

2. Lack of Awareness

Many Indians dismiss mental fatigue or forgetfulness as simple tiredness. This leads to underreporting and delayed treatment. Now, with growing awareness, more people are coming forward with their symptoms.

3. Urban Lifestyle and Pollution

Stressful jobs, long commutes, and air pollution can all weaken the immune system. This makes urban populations more vulnerable to severe post-viral symptoms, including brain fog.

4. Inadequate Recovery Time

In many Indian households, people return to work or daily duties too soon after illness. Without proper rest and nutrition, the brain doesn't get enough time to recover.

 

How Long Does Brain Fog Last?

The duration of brain fog varies. For some, it lasts just a few days. For others, especially post-COVID patients, it can linger for weeks or even months. If symptoms continue beyond 3–4 weeks, it’s advisable to consult a doctor or neurologist.

 

How to Recover From Brain Fog?

The good news is that brain fog is usually temporary. Here are some effective strategies to recover faster:

1. Prioritize Sleep

Getting 7–9 hours of good quality sleep every night is essential for brain recovery. Stick to a regular sleep schedule and avoid screens before bedtime.

2. Eat a Brain-Boosting Diet

Include foods rich in omega-3, antioxidants, and vitamins like:

  • Fatty fish (salmon, sardines)

  • Nuts and seeds

  • Green leafy vegetables

  • Berries

  • Whole grains

  • Eggs
     

3. Stay Hydrated

Dehydration can worsen brain fog. Drink at least 2–3 liters of water daily, especially if you’ve had fever or diarrhea during the illness.

4. Reduce Stress

Practice relaxation techniques like meditation, yoga, or deep breathing. Mental stress adds to the burden your brain is already dealing with.

5. Light Physical Activity

Gentle exercises like walking or stretching can improve blood flow to the brain and aid recovery.

6. Limit Screen Time

Excessive mobile and laptop use can strain your brain. Take regular breaks and try to spend more time offline.

7. Mental Exercises

Try memory games, puzzles, reading, or learning a new skill to stimulate brain function.

 

When to Seek Medical Help

If your symptoms include severe confusion, frequent memory loss, or difficulty with basic tasks, don’t ignore it. Visit a neurologist or psychiatrist for evaluation. Early intervention can prevent long-term complications.

 

What Can Families and Employers Do?

  • Be Understanding: People recovering from viral illnesses may not be at their mental best. Show patience and empathy.
     

  • Encourage Breaks: Allow flexible schedules or work-from-home options for recovering employees.
     

  • Educate Others: Spread awareness about post-viral symptoms like brain fog so that more people recognize and address it early.
     

 

Conclusion

Brain fog after viral infections is real, and it’s affecting a large number of Indians more than ever before. As viruses continue to evolve and impact our lives, it’s important to recognize the lingering symptoms that come after the fever and cough are gone. Understanding the causes, taking preventive steps, and giving your body the time it needs to heal can make a big difference in mental clarity and long-term brain health.

If you or someone you know is experiencing confusion, memory loss, or difficulty focusing after recovering from an illness, don’t brush it off. You’re not alone. Many are going through the same – and help is available.

Take action today to protect your cognitive health and stay informed about brain fog after viral infections: why so many Indians are reporting memory issues.

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