• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Impact of Junk Food on Hormonal Balance

Impact of Junk Food on Hormonal Balance

In today's fast-paced world, junk food has become a popular choice for many people. It is easily available, quick to eat, and often tasty. But behind the delicious flavors and convenience lies a growing health concern. Junk food is not just about empty calories — it has deeper effects on our bodies, especially on our hormones. Hormones are chemical messengers that control important functions in the body like growth, mood, metabolism, and reproduction. When your hormonal balance is disturbed, it can lead to serious health issues.

In this blog, we will explore how junk food affects hormonal balance and why it's important to make healthier food choices for a better life.

 

What Is Junk Food?

Junk food refers to food that is high in calories but low in nutrients. These foods are often loaded with:

  • Refined sugar

  • Unhealthy fats (trans fats and saturated fats)

  • Salt

  • Preservatives and additives
     

Common examples include chips, candies, sugary drinks, fast food (like burgers and fries), pastries, and processed snacks.

While having junk food occasionally is not harmful, regular consumption can have negative effects, especially on your hormones.

 

What Are Hormones and Why Are They Important?

Hormones are chemicals produced by glands in the endocrine system. They travel through the blood and affect many parts of the body. Hormones are responsible for:

  • Regulating metabolism

  • Controlling appetite

  • Balancing mood

  • Managing stress

  • Supporting growth and development

  • Controlling sexual function and reproductive health
     

Even a small imbalance in hormone levels can affect your physical and emotional well-being.

 

How Junk Food Affects Hormonal Balance

1. Insulin Resistance and Blood Sugar Spikes

Many junk foods are high in refined sugars and simple carbohydrates. When you eat them, your blood sugar levels rise quickly, and your body releases insulin to control it. Over time, repeated spikes can lead to insulin resistance, a condition where the body stops responding to insulin properly.

Hormonal impact:

  • Leads to type 2 diabetes

  • Causes weight gain, which further disrupts hormone levels

  • Can affect reproductive hormones, especially in women (e.g., PCOS)
     

 

2. Increased Cortisol Levels (Stress Hormone)

Junk food can cause inflammation and oxidative stress in the body. These physical stressors raise cortisol levels. High cortisol over time can:

  • Disrupt sleep

  • Lower immunity

  • Cause belly fat

  • Create mood swings or anxiety
     

Hormonal impact:
Cortisol imbalance throws off the natural rhythm of other hormones, like melatonin (sleep hormone) and serotonin (mood hormone).

 

3. Leptin Resistance (Hunger Hormone)

Leptin is the hormone that signals fullness to your brain. When you eat too much high-fat, high-sugar junk food, your brain can stop recognizing leptin signals — a condition known as leptin resistance.

Hormonal impact:

  • Constant feeling of hunger

  • Overeating and obesity

  • Poor appetite control

  • Disruption of metabolism and thyroid hormones
     

 

4. Imbalanced Sex Hormones

Junk food, especially processed meat and dairy, may contain hormone-disrupting chemicals. Additionally, high body fat from poor eating habits increases estrogen production in both men and women.

Hormonal impact:

  • In men: Low testosterone, reduced fertility

  • In women: Irregular periods, PCOS, mood changes, fertility issues
     

 

5. Thyroid Hormone Disruption

A diet high in sodium, sugar, and bad fats may affect the thyroid gland, which regulates metabolism through hormones like T3 and T4. Processed junk foods often contain preservatives and artificial additives that interfere with the absorption of iodine, a key mineral for thyroid function.

Hormonal impact:

  • Slowed metabolism

  • Weight gain

  • Fatigue

  • Depression
     

 

Signs of Hormonal Imbalance Due to Junk Food

Here are some common signs your hormones might be off track because of poor diet:

  • Unexplained weight gain or difficulty losing weight

  • Constant fatigue or low energy

  • Mood swings, anxiety, or depression

  • Irregular periods or fertility issues

  • Sleep problems or insomnia

  • Acne or skin issues

  • Sugar cravings and increased appetite
     

If you're experiencing these symptoms, it’s a sign that your hormones might be out of balance, and your diet could be playing a big role.

 

Simple Ways to Support Hormonal Health

While avoiding junk food completely might be hard, you can take simple steps to support your hormones:

1. Eat Whole Foods

Include more fruits, vegetables, whole grains, lean proteins, and healthy fats in your diet.

2. Stay Hydrated

Drink enough water every day. Hydration helps with hormone transport and overall health.

3. Exercise Regularly

Exercise improves insulin sensitivity and helps regulate stress hormones like cortisol.

4. Sleep Well

Good quality sleep is essential for hormone production and regulation.

5. Reduce Stress

Practice meditation, yoga, deep breathing, or spend time in nature.

6. Limit Sugar and Processed Foods

Read food labels and avoid products with high sugar, trans fats, and artificial additives.

 

Final Thoughts

Your body is a delicate machine that runs on balance — especially hormonal balance. Junk food may seem like a small indulgence, but its long-term effects on your hormones can be serious. From weight gain and mood swings to fertility issues and chronic fatigue, the consequences of poor diet choices can be far-reaching.

Making mindful changes to your eating habits doesn’t mean you have to give up everything you love. It simply means prioritizing your health by choosing more natural, wholesome foods most of the time.

 

Conclusion

The impact of junk food on hormonal balance is a growing concern in modern health. If you're struggling with symptoms like fatigue, mood changes, or weight gain, it's time to look at your plate. By reducing junk food and eating clean, you can bring your hormones back into harmony and improve your overall well-being. Start today — your body and mind will thank you.

Take the first step toward better health and avoid the impact of junk food on hormonal balance.

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