What is the normal range of SGPT and SGOT?

SGPT (ALT): 7–56 U/L and SGOT (AST): 8–48 U/L. Ranges may slightly vary depending on the lab.

Is fasting required before a liver enzyme test?

Fasting is not always required. Follow your doctor's or diagnostic lab’s instructions.

Which tests should I take for a complete liver check-up?

A full Liver Function Test (LFT) is ideal. It includes SGPT, SGOT, Bilirubin, ALP, GGT, and proteins like Albumin.

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Published on: May 21, 2025
4 minute read
By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

SGPT (ALT) – Serum Glutamic Pyruvic Transaminase
SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

Fatigue or weakness
Yellowing of skin or eyes (jaundice)
Abdominal pain or swelling
Dark urine or pale stools
Alcohol consumption
Hepatitis (A, B, or C)
Obesity or fatty liver
Long-term medication usage
Diabetes or high cholesterol

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

For men: 7 to 56 units per liter of blood
For women: 7 to 45 units per liter

What Does High SGPT Mean?

High SGPT levels may indicate:

Liver inflammation (Hepatitis)
Fatty liver disease
Alcohol-related liver damage
Liver infection or injury
Side effects of medications
Obesity-related liver stress

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

For men: 8 to 48 units per liter of blood
For women: 8 to 43 units per liter

What Does High SGOT Mean?

High SGOT levels may be due to:

Liver damage or cirrhosis
Heart disease or recent heart attack
Muscle injuries
Pancreatitis
Alcohol abuse
Use of certain drugs or supplements

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature	SGPT (ALT)	SGOT (AST)
Location	Mainly in the liver	Liver, heart, kidneys, muscles, brain
Specificity	More liver-specific	Less liver-specific
Indicates	Liver damage	Liver, heart, or muscle damage
Normal Range	7–56 U/L	8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

ALP (Alkaline Phosphatase) – Linked to bile ducts
GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems
Bilirubin – Indicates liver’s ability to process waste
Albumin and Total Protein – Reflects liver's protein production
PT/INR – Measures blood clotting, another liver function

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

Avoid alcohol completely
Maintain a healthy diet (low-fat, high-fiber)
Exercise regularly
Control blood sugar and cholesterol
Stay hydrated

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

Yellow eyes or skin (jaundice)
Severe abdominal pain
Swelling in legs or abdomen
Confusion or mood changes
Dark-colored urine or light-colored stools

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

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Read FAQs

A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

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Human Metapneumovirus (HMPV): Treatment & Symptoms

Human Metapneumovirus (HMPV) is a respiratory virus that causes illness in people of all ages, particularly young children, older adults, and people with weakened immune systems. The virus can lead to conditions such as bronchitis, pneumonia, and upper respiratory infections. With rising cases globally and in India, awareness about HMPV, its symptoms, and available treatment options is essential.

In this blog, we'll break down everything you need to know about Human Metapneumovirus (HMPV): Treatment & Symptoms in easy-to-understand language.

What is Human Metapneumovirus (HMPV)?

HMPV is a virus that belongs to the Paramyxoviridae family—the same group of viruses responsible for illnesses like RSV (Respiratory Syncytial Virus) and mumps. It was first discovered in 2001 but is now known to have been circulating for decades.

The virus mainly affects the respiratory tract and can range from mild cold-like symptoms to severe lower respiratory infections. It spreads most commonly in late winter and spring, similar to flu season.

HMPV in India: Current Overview

In 2025, several hospitals in India have seen a rise in cases of HMPV among children and elderly patients. Though not as widely known as COVID-19 or flu, Human Metapneumovirus is a common cause of pediatric hospital admissions during respiratory infection surges.

Doctors advise taking it seriously because it can mimic flu or pneumonia, making early diagnosis crucial.

Common Symptoms of HMPV

The symptoms of HMPV are similar to other respiratory viruses. They can range from mild cold-like symptoms to severe breathing difficulties, especially in vulnerable groups.

Main Symptoms Include:

Fever
Cough
Runny nose
Nasal congestion
Sore throat
Wheezing
Shortness of breath
Fatigue
Loss of appetite (especially in children)

In severe cases, it can lead to bronchitis or pneumonia.

How is HMPV Transmitted?

Human Metapneumovirus spreads from person to person through:

Coughing and sneezing
Close personal contact
Touching contaminated surfaces or hands

The virus can survive on surfaces like toys, doorknobs, and tables for several hours. That’s why regular handwashing and hygiene are essential.

How is HMPV Diagnosed?

Since HMPV symptoms resemble other viral infections, a lab test is the only way to confirm the virus.

Tests may include:

RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) for detecting viral RNA
Nasopharyngeal swabs
Rapid antigen tests (less common)

In India, you can book respiratory virus panels or flu-like illness tests from diagnostic labs like Thyrocare through SecondMedic to check for multiple viruses including HMPV.

Human Metapneumovirus (HMPV): Treatment

There is no specific antiviral drug for HMPV. Treatment is mainly supportive, aimed at relieving symptoms.

Supportive Treatments:

Fever reducers like paracetamol
Cough suppressants
Steam inhalation
Hydration (drinking fluids)
Rest

Hospitalization is required if:

Breathing becomes difficult
Oxygen levels drop
Patient is elderly, a young child, or has chronic illnesses (like asthma or heart disease)

Doctors may provide oxygen therapy or nebulizers to ease breathing in severe cases.

How to Prevent HMPV

As with many respiratory infections, prevention is the best protection.

Tips to Avoid Infection:

Wash your hands regularly with soap and water.
Use alcohol-based hand sanitizers when outside.
Cover mouth and nose when sneezing or coughing.
Avoid touching your face, especially eyes and nose.
Disinfect commonly used surfaces at home and work.
Avoid close contact with sick individuals.
Wear a mask in crowded places during flu season.

There is no vaccine for HMPV yet, but researchers are working on developing one.

Who is Most at Risk?

Infants and toddlers (under 5 years)
Adults over 65
People with weakened immune systems
Individuals with chronic respiratory or heart diseases

These groups may experience more severe symptoms and need urgent care if infected.

When to See a Doctor

You should consult a doctor if:

Symptoms last more than 5–7 days
Breathing becomes difficult
Fever is very high or persistent
There's chest pain or confusion
A child has a bluish face or lips

Early intervention can prevent complications.

Recommended Tests on SecondMedic (Powered by Thyrocare)

While there is no HMPV-specific test for home collection, you can book tests like:

Complete Blood Count (CBC)
CRP (C-Reactive Protein)
Respiratory Pathogen Panel
Influenza A & B Detection
RT-PCR Viral Panels (on request)

Visit SecondMedic’s Lab Test Section to explore packages and book your test online.

Conclusion

Human Metapneumovirus (HMPV) is a growing cause of respiratory illness in India, especially in children and the elderly. Though there is no specific cure, early diagnosis and symptom-based treatment can help patients recover fully. Practicing good hygiene and avoiding close contact with sick people are the best ways to prevent infection.

Stay informed and protect your loved ones. For detailed insights and medical advice, bookmark this guide on "Human Metapneumovirus (HMPV): Treatment & Symptoms."

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