What is the normal range of SGPT and SGOT?

SGPT (ALT): 7–56 U/L and SGOT (AST): 8–48 U/L. Ranges may slightly vary depending on the lab.

Is fasting required before a liver enzyme test?

Fasting is not always required. Follow your doctor's or diagnostic lab’s instructions.

Which tests should I take for a complete liver check-up?

A full Liver Function Test (LFT) is ideal. It includes SGPT, SGOT, Bilirubin, ALP, GGT, and proteins like Albumin.

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Published on: May 21, 2025
4 minute read
By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

SGPT (ALT) – Serum Glutamic Pyruvic Transaminase
SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

Fatigue or weakness
Yellowing of skin or eyes (jaundice)
Abdominal pain or swelling
Dark urine or pale stools
Alcohol consumption
Hepatitis (A, B, or C)
Obesity or fatty liver
Long-term medication usage
Diabetes or high cholesterol

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

For men: 7 to 56 units per liter of blood
For women: 7 to 45 units per liter

What Does High SGPT Mean?

High SGPT levels may indicate:

Liver inflammation (Hepatitis)
Fatty liver disease
Alcohol-related liver damage
Liver infection or injury
Side effects of medications
Obesity-related liver stress

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

For men: 8 to 48 units per liter of blood
For women: 8 to 43 units per liter

What Does High SGOT Mean?

High SGOT levels may be due to:

Liver damage or cirrhosis
Heart disease or recent heart attack
Muscle injuries
Pancreatitis
Alcohol abuse
Use of certain drugs or supplements

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature	SGPT (ALT)	SGOT (AST)
Location	Mainly in the liver	Liver, heart, kidneys, muscles, brain
Specificity	More liver-specific	Less liver-specific
Indicates	Liver damage	Liver, heart, or muscle damage
Normal Range	7–56 U/L	8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

ALP (Alkaline Phosphatase) – Linked to bile ducts
GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems
Bilirubin – Indicates liver’s ability to process waste
Albumin and Total Protein – Reflects liver's protein production
PT/INR – Measures blood clotting, another liver function

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

Avoid alcohol completely
Maintain a healthy diet (low-fat, high-fiber)
Exercise regularly
Control blood sugar and cholesterol
Stay hydrated

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

Yellow eyes or skin (jaundice)
Severe abdominal pain
Swelling in legs or abdomen
Confusion or mood changes
Dark-colored urine or light-colored stools

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

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Read FAQs

A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

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CRP Test Meaning and When to Do It

If you’ve recently had blood work or your doctor suspects an infection or inflammation, they may have recommended a CRP test. But what is it? Why is it important? And when exactly should you get it done?

Let’s simplify the medical jargon and walk you through the CRP test meaning and when to do it, especially in the Indian healthcare context.

What Is a CRP Test?

CRP stands for C-reactive protein. It is a substance produced by your liver in response to inflammation in the body.

The CRP test is a blood test that measures the amount of C-reactive protein in your blood. High levels of CRP usually mean there’s inflammation in your body, which could be due to an infection, injury, or a chronic disease like arthritis.

High CRP = Inflammation Alert

This test doesn’t tell you what’s causing the inflammation—it simply tells you that something is wrong, and further testing might be needed.

What Does the CRP Test Detect?

While CRP is a general marker, it is helpful in detecting:

Bacterial or viral infections
Autoimmune disorders like rheumatoid arthritis or lupus
Inflammatory bowel diseases
COVID-19 severity
Heart disease risk (especially with high-sensitivity CRP or hs-CRP)

When Should You Do a CRP Test?

You should get a CRP test done when:

You have fever or chills that won’t go away
You’re showing signs of infection like cough, swelling, or pain
Your doctor is monitoring an autoimmune disease
You’re recovering from surgery or injury
Your doctor is checking inflammation due to chronic disease
You are showing COVID-like symptoms (to assess severity)

Normal CRP Levels:

CRP Level	Interpretation
Below 1 mg/L	Low risk of inflammation
1–3 mg/L	Moderate risk
Above 3 mg/L	High inflammation or infection present
Above 10 mg/L	May indicate serious infection or disease

Note: For heart disease risk, a high-sensitivity CRP (hs-CRP) test is used.

Is Fasting Required for the CRP Test?

No, fasting is not required. You can take the CRP test at any time of day, unless it is being done with other tests that require fasting (like blood sugar or cholesterol).

Lab Tests Packages Including CRP

You can book a CRP test alone or as part of a health package via SecondMedic.com, powered by Thyrocare:

Basic CRP Test

Detects inflammation/infection
Simple blood draw
Home sample collection

COVID Monitoring Panel

CRP, D-Dimer, Ferritin, CBC
Recommended if you have COVID symptoms or are recovering

Inflammation Panel

CRP + ESR + CBC + Liver Profile
For those with chronic fatigue, joint pain, or autoimmune diseases

Lifestyle Tips If Your CRP is High

A high CRP may indicate ongoing inflammation. Along with medical treatment, here are some tips:

Eat more fruits, vegetables, and whole grains
Cut down on sugar and processed food
Include omega-3 rich foods like flaxseed and fish
Exercise regularly
Manage stress and sleep better
Quit smoking and limit alcohol

5 Most Asked Questions About the CRP Test

1. What is the CRP test used for?

CRP tests are used to check for inflammation due to infections, autoimmune diseases, and to monitor treatment effectiveness.

2. What causes a high CRP level?

Infections, chronic inflammation, surgery, injuries, and lifestyle diseases like diabetes and heart disease.

3. Is a CRP test painful?

No. It’s a simple blood test and usually takes just a few minutes.

4. How long does it take to get CRP test results?

Most labs deliver CRP results within 24 to 48 hours.

5. Can CRP levels return to normal?

Yes, with proper treatment and lifestyle changes, CRP levels can go back to the normal range.

Booking a CRP Test Online (Thyrocare via SecondMedic)

Here’s how you can book it:

Go to www.secondmedic.com
Search for "CRP Test – Thyrocare"
Select home sample collection
Enter your location and schedule pickup
Get digital results within 1–2 days

Conclusion

The CRP test is a simple, affordable, and powerful tool to detect inflammation early. Whether you’re dealing with an infection, monitoring a chronic condition, or recovering from illness, this test gives your doctor a clearer picture of what’s happening inside your body.

Don’t ignore signs like unexplained fever, fatigue, or body pain. Get tested.

If you’re wondering about CRP test meaning and when to do it — the answer is simple: whenever inflammation or infection is suspected, this test is your body's alert system.

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