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Published on: Oct 28, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Hepatitis C Nobel Prize

Earlier this month the Nobel Prize in Physiology and Medicine was jointly awarded to Harvey J Alter, Michael Houghton and Charles M Rice for the discovery of the Hepatitis C virus. This helped push our understanding of blood-borne hepatitis, a major global health problem that is one of the leading causes of cirrhosis and liver cancer alongside Hepatitis B. It led the way in introducing new tests for chronic hepatitis as well as new treatments that have saved the lives of millions.

HEPATITIS

Hepatitis is the inflammation of your liver, the largest solid organ in your body. Though there are numerous other causes of hepatitis, including alcohol abuse, drugs and toxins (including paracetamol overdose), and autoimmune disorders (such as Wilson’s disease), viral infections are the most common worldwide causes for hepatitis. Hepatitis A was the first to be discovered, transmitted by polluted food and water, and results in a short-term transient hepatitis. Hepatitis B on the other hand is transmitted through blood and is more of an issue as it can lead to chronic cirrhosis and possible liver cancer. It can remain indolent in a person, causing disease long after the initial infection.

Blood borne hepatitis was first discovered in the 1960s, when it was found that some patients would become ill after receiving blood transfusions. Despite this discovery and new tests for Hepatitis B reducing the number of transfusion related hepatitis, a large number of cases remained.

NOT A, NOT B

Harvey Alter, working at the US National Institute of Health, was studying the occurrence of hepatitis in blood transfusion patients. His team showed that blood from these infected patients could transmit the disease to chimpanzees, resulting in hepatitis. This agent had the properties of a virus, one that was “non-A, non B” hepatitis.

Further investigation into the virus would require the input of Michael Houghton, working for Chiron pharmaceutical. His team created a collection of DNA fragments found in the blood of infected chimpanzees. Though the majority of these fragments were from the chimpanzee, enough were from the virus. They were able to utilise this information to identify antibodies against the suspected virus, and ultimately identify it as the flavivirus Hepatitis C.

The final piece of the puzzle was shown by Charles M Rice, a researcher at Washington University, St Louis – could the virus alone cause hepatitis. He studied the RNA of Hepatitis C to identify regions that may be used for replication, and areas that might hinder replication. This was key as the virus can lay dormant for years, replicating at a slow rate before causing damage to the liver. For researchers, this was an issue as it was not feasible to wait years and see if the suspected virus caused hepatitis. By genetically engineering the viral genome, he developed a variant of Hepatitis C that would only multiple rapidly and have no mechanism to inactivate itself for dormancy. This strain caused rapid changes to the livers of infected chimpanzees; the same changes seen in hepatitis patients.

. ;.,hrvxzThe impact was significant. Prior to this, receiving a blood transfusion was like Russian Roulette. You were receiving life saving therapy, but it coZuld also be a hidden death sentence. Now that hepatitis had been discovered, it became possible to screen patients prior to donation, to screen blood transfusion bags, and to start developing treatments for the virus.

The fight is not over yet. There are still over 70 million people who still live with the virus, and it still kills around 400,000 a year. Its only very recently that we have found treatments that can reduce the viral load in patients to levels that they are considered cured. This treatment remains expensive, and we are very far away from eradication itself.

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Monthly Field Day with Patients & Staff: Building Stronger Connections for Better Health

Healthcare outcomes are shaped not only by medical treatments but also by trust, communication and community engagement. As healthcare systems in India move toward preventive and patient-centric models, initiatives that foster meaningful interaction between patients and healthcare professionals are gaining importance. One such initiative is the Monthly Field Day with Patients & Staff.

A field day creates a shared space where patients and healthcare teams interact beyond clinical settings. These interactions humanise healthcare, improve understanding and encourage long-term wellness practices.

Why Community Engagement Matters in Healthcare

Modern healthcare recognises that health is influenced by behaviour, awareness and social support. According to the World Health Organization (WHO) and NITI Aayog, community-based health engagement improves preventive care adoption and patient outcomes.

Field days help bridge the gap between healthcare providers and patients by:

encouraging open dialogue
reducing fear and hesitation
promoting shared responsibility for health

What Is a Monthly Field Day with Patients & Staff?

A Monthly Field Day with Patients & Staff is a structured wellness initiative organised outside the routine clinical environment. It focuses on interaction, education and preventive health activities.

Typical elements include:

basic health screenings
lifestyle education sessions
fitness or relaxation activities
informal conversations with healthcare staff
family and caregiver participation

The aim is to create a supportive and approachable healthcare experience.

Why Monthly Frequency Matters

Consistency is key in behaviour change and preventive health.

Monthly field days:

reinforce health messages regularly
build familiarity and trust
allow continuous follow-up
keep wellness top of mind

According to public health studies, repeated engagement significantly improves health literacy and adherence.

Benefits for Patients

1. Improved Health Awareness

Patients gain better understanding of:

chronic disease management
preventive screenings
nutrition and lifestyle habits

Education in informal settings improves retention.

2. Increased Comfort with Healthcare Teams

Regular interaction reduces anxiety and hesitation around seeking medical care.

Patients are more likely to:

ask questions
follow medical advice
attend follow-ups

3. Early Risk Identification

Field days often include basic screenings that help detect:

high blood pressure
elevated blood sugar
obesity risk

Early identification enables timely intervention.

4. Enhanced Emotional Wellbeing

Social interaction and community activities reduce feelings of isolation, especially among elderly or chronically ill patients.

Benefits for Healthcare Staff

1. Better Understanding of Patient Needs

Direct interaction outside clinical settings helps staff understand patient challenges more holistically.

2. Improved Communication Skills

Informal engagement strengthens empathy and communication effectiveness.

3. Reduced Burnout

Positive patient interaction and community appreciation contribute to staff morale and job satisfaction.

WHO recognises staff wellbeing as a critical factor in healthcare quality.

Role of Field Days in Preventive Healthcare

Preventive healthcare focuses on reducing disease burden before complications arise. Field days support prevention by:

promoting routine screenings
encouraging healthy lifestyle habits
addressing myths and misconceptions
reinforcing long-term care plans

NITI Aayog identifies community engagement as a cornerstone of preventive healthcare strategies.

Activities Commonly Included in Field Days

Health Screening Stations

Blood pressure, blood sugar, BMI and basic assessments.

Wellness Education

Short talks on nutrition, exercise, sleep and stress.

Interactive Sessions

Q&A discussions with doctors, nurses and health educators.

Physical Activities

Group walks, yoga sessions or light exercises.

Family Engagement

Including caregivers improves adherence and support systems.

Impact on Chronic Disease Management

For patients with chronic conditions such as diabetes or hypertension, regular engagement:

improves medication adherence
reinforces lifestyle modification
reduces emergency visits

Lancet studies highlight that community-based interventions improve chronic disease outcomes.

Building Trust Through Transparency

Field days foster trust by:

making healthcare providers approachable
encouraging open dialogue
demonstrating commitment to patient wellbeing

Trust improves treatment adherence and satisfaction.

Role of Data and Feedback

Feedback collected during field days helps healthcare organisations:

identify common concerns
refine wellness programs
personalise future interventions

Data-driven engagement enhances program effectiveness.

Long-Term Impact on Healthcare Outcomes

Organisations that invest in regular patient-staff engagement observe:

higher patient satisfaction
improved preventive screening rates
reduced disease complications
stronger community relationships

According to WHO, patient-centred care models improve health outcomes and system efficiency.

Why Field Days Are Especially Relevant in India

India’s diverse population faces challenges such as:

limited health literacy
delayed care-seeking
chronic disease burden

Community-based initiatives like field days address these challenges through education and trust-building.

Conclusion

A Monthly Field Day with Patients & Staff is more than a community event—it is a strategic preventive healthcare initiative. By fostering open communication, promoting health awareness and strengthening relationships, field days improve patient engagement and staff wellbeing alike. In a healthcare landscape increasingly focused on prevention and community trust, regular field days play a vital role in building healthier, more connected communities.

References

ICMR – Community Health and Preventive Care Reports
National Family Health Survey (NFHS-5) – Health Awareness and Engagement Dat
NITI Aayog – Community-Based Preventive Healthcare Strategies
WHO – Patient-Centred Care and Community Health Guidelines
Lancet – Community Engagement and Health Outcome Studies
Statista – Healthcare Engagement and Preventive Care Trends India
EY-FICCI – Healthcare Workforce and Patient Engagement Reports

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