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Published on: Oct 28, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Hepatitis C Nobel Prize

Earlier this month the Nobel Prize in Physiology and Medicine was jointly awarded to Harvey J Alter, Michael Houghton and Charles M Rice for the discovery of the Hepatitis C virus. This helped push our understanding of blood-borne hepatitis, a major global health problem that is one of the leading causes of cirrhosis and liver cancer alongside Hepatitis B. It led the way in introducing new tests for chronic hepatitis as well as new treatments that have saved the lives of millions.

HEPATITIS

Hepatitis is the inflammation of your liver, the largest solid organ in your body. Though there are numerous other causes of hepatitis, including alcohol abuse, drugs and toxins (including paracetamol overdose), and autoimmune disorders (such as Wilson’s disease), viral infections are the most common worldwide causes for hepatitis. Hepatitis A was the first to be discovered, transmitted by polluted food and water, and results in a short-term transient hepatitis. Hepatitis B on the other hand is transmitted through blood and is more of an issue as it can lead to chronic cirrhosis and possible liver cancer. It can remain indolent in a person, causing disease long after the initial infection.

Blood borne hepatitis was first discovered in the 1960s, when it was found that some patients would become ill after receiving blood transfusions. Despite this discovery and new tests for Hepatitis B reducing the number of transfusion related hepatitis, a large number of cases remained.

NOT A, NOT B

Harvey Alter, working at the US National Institute of Health, was studying the occurrence of hepatitis in blood transfusion patients. His team showed that blood from these infected patients could transmit the disease to chimpanzees, resulting in hepatitis. This agent had the properties of a virus, one that was “non-A, non B” hepatitis.

Further investigation into the virus would require the input of Michael Houghton, working for Chiron pharmaceutical. His team created a collection of DNA fragments found in the blood of infected chimpanzees. Though the majority of these fragments were from the chimpanzee, enough were from the virus. They were able to utilise this information to identify antibodies against the suspected virus, and ultimately identify it as the flavivirus Hepatitis C.

The final piece of the puzzle was shown by Charles M Rice, a researcher at Washington University, St Louis – could the virus alone cause hepatitis. He studied the RNA of Hepatitis C to identify regions that may be used for replication, and areas that might hinder replication. This was key as the virus can lay dormant for years, replicating at a slow rate before causing damage to the liver. For researchers, this was an issue as it was not feasible to wait years and see if the suspected virus caused hepatitis. By genetically engineering the viral genome, he developed a variant of Hepatitis C that would only multiple rapidly and have no mechanism to inactivate itself for dormancy. This strain caused rapid changes to the livers of infected chimpanzees; the same changes seen in hepatitis patients.

. ;.,hrvxzThe impact was significant. Prior to this, receiving a blood transfusion was like Russian Roulette. You were receiving life saving therapy, but it coZuld also be a hidden death sentence. Now that hepatitis had been discovered, it became possible to screen patients prior to donation, to screen blood transfusion bags, and to start developing treatments for the virus.

The fight is not over yet. There are still over 70 million people who still live with the virus, and it still kills around 400,000 a year. Its only very recently that we have found treatments that can reduce the viral load in patients to levels that they are considered cured. This treatment remains expensive, and we are very far away from eradication itself.

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Dairy-Free Options for All: A Comprehensive SecondMedic Guide for India

Dairy consumption has long been a part of Indian dietary culture, but rising awareness of digestive health, metabolic concerns, acne, inflammation and lactose intolerance has encouraged many individuals to explore dairy-free alternatives. India is experiencing a significant shift toward plant-based nutrition as people prioritise preventive health, gut comfort and personalised dietary choices.

SecondMedic’s nutrition experts emphasise evidence-based, dairy-free patterns that support digestion, hormonal balance, metabolic stability and overall wellbeing. This guide explores the best dairy-free options in India, their health benefits and how they integrate into daily preventive care.

Why Dairy-Free Eating Is Growing in India

1. Rising Lactose Intolerance

According to ICMR Digestive Health Trends, a high percentage of Indian adults experience lactose intolerance due to decreased lactase enzyme activity.

Common symptoms include:

Bloating
Gas
Acidity
Diarrhoea
Skin flare-ups

Dairy-free alternatives eliminate these discomforts.

2. Skin & Hormonal Concerns

Dairy may influence acne, PCOS symptoms and inflammation in certain individuals.

3. Improved Digestibility

Many plant-based options are easier on the gut and reduce inflammation.

4. Increasing Nutrition Awareness

NFHS-5 highlights micronutrient deficiencies-including Vitamin D and B12-leading people to choose fortified dairy-free alternatives.

Popular Dairy-Free Options in India

1. Almond Milk

Rich in Vitamin E and naturally low in calories.
Ideal for smoothies, coffee and cereal.

2. Soy Milk

High in protein and often fortified with calcium.
Great for cooking and baking.

3. Oat Milk

Creamy texture, high in soluble fibre.
Excellent for lattes and desserts.

4. Coconut Milk

Rich flavour, suitable for Indian curries and smoothies.

5. Nut-Based Yoghurt

Cashew and almond curds have become widely available.
Probiotic varieties support gut health.

6. Tofu & Plant-Based Paneer

Excellent protein source for vegetarians.

7. Lactose-Free Dairy

For those who prefer traditional taste without digestive discomfort.

Nutritional Benefits of Dairy-Free Options

1. Reduced Inflammation

Studies in Lancet Public Health show improved gut comfort among individuals switching to dairy-free diets.

2. Hormonal Balance

Plant-based alternatives help regulate insulin, estrogen and androgen patterns-especially valuable for PCOS and thyroid care.

3. Weight Management

Lower calorie load and better digestibility support metabolic health.

4. Allergy-Friendly Choice

A safe option for individuals sensitive to casein or whey proteins.

How to Build a Balanced Dairy-Free Diet

Ensure calcium intake:

Choose fortified plant milks.

Include plant proteins:

Tofu, dals, nuts and seeds.

Add healthy fats:

Ground flaxseed, chia and almonds.

Combine traditional and modern options:

Oat milk chai, tofu tikka, nut curd raita.

SecondMedic’s AI nutrition scoring helps evaluate vitamin density and carbohydrate load for optimal choices.

Dairy-Free Meal Examples

Breakfast

• Oats cooked with almond milk
• Fruit + chia seeds + nuts

Lunch

• Millet khichdi with tofu
• Vegetable salad with tahini dressing

Snack

• Coconut yoghurt with berries

Dinner

• Stir-fry vegetables with tofu
• Whole-grain roti + plant-based curd

Conclusion

Dairy-free options provide flexible, nutritious and preventive pathways for individuals across India. Whether motivated by digestive comfort, metabolic health, ethical choices or personal preference, dairy-free alternatives support long-term wellness. SecondMedic helps individuals evaluate and incorporate dairy-free nutrition through expert consultations, AI-based analysis and personalised dietary planning.

References

• ICMR Digestive Health & Lactose Intolerance Study
• National Family Health Survey (NFHS-5) - Nutrition & Dietary Patterns
• NITI Aayog - Plant-Based Nutrition & Preventive Wellness Framework
• WHO Guidelines on Healthy Dietary Alternatives
• Lancet Public Health - Dairy-Free Diets & Inflammation Research
• Statista India Plant-Based Food Market Analysis
• EY-FICCI Food Innovation & Health Trends Report

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