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Published on: Oct 28, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Hepatitis C Nobel Prize

Earlier this month the Nobel Prize in Physiology and Medicine was jointly awarded to Harvey J Alter, Michael Houghton and Charles M Rice for the discovery of the Hepatitis C virus. This helped push our understanding of blood-borne hepatitis, a major global health problem that is one of the leading causes of cirrhosis and liver cancer alongside Hepatitis B. It led the way in introducing new tests for chronic hepatitis as well as new treatments that have saved the lives of millions.

HEPATITIS

Hepatitis is the inflammation of your liver, the largest solid organ in your body. Though there are numerous other causes of hepatitis, including alcohol abuse, drugs and toxins (including paracetamol overdose), and autoimmune disorders (such as Wilson’s disease), viral infections are the most common worldwide causes for hepatitis. Hepatitis A was the first to be discovered, transmitted by polluted food and water, and results in a short-term transient hepatitis. Hepatitis B on the other hand is transmitted through blood and is more of an issue as it can lead to chronic cirrhosis and possible liver cancer. It can remain indolent in a person, causing disease long after the initial infection.

Blood borne hepatitis was first discovered in the 1960s, when it was found that some patients would become ill after receiving blood transfusions. Despite this discovery and new tests for Hepatitis B reducing the number of transfusion related hepatitis, a large number of cases remained.

NOT A, NOT B

Harvey Alter, working at the US National Institute of Health, was studying the occurrence of hepatitis in blood transfusion patients. His team showed that blood from these infected patients could transmit the disease to chimpanzees, resulting in hepatitis. This agent had the properties of a virus, one that was “non-A, non B” hepatitis.

Further investigation into the virus would require the input of Michael Houghton, working for Chiron pharmaceutical. His team created a collection of DNA fragments found in the blood of infected chimpanzees. Though the majority of these fragments were from the chimpanzee, enough were from the virus. They were able to utilise this information to identify antibodies against the suspected virus, and ultimately identify it as the flavivirus Hepatitis C.

The final piece of the puzzle was shown by Charles M Rice, a researcher at Washington University, St Louis – could the virus alone cause hepatitis. He studied the RNA of Hepatitis C to identify regions that may be used for replication, and areas that might hinder replication. This was key as the virus can lay dormant for years, replicating at a slow rate before causing damage to the liver. For researchers, this was an issue as it was not feasible to wait years and see if the suspected virus caused hepatitis. By genetically engineering the viral genome, he developed a variant of Hepatitis C that would only multiple rapidly and have no mechanism to inactivate itself for dormancy. This strain caused rapid changes to the livers of infected chimpanzees; the same changes seen in hepatitis patients.

. ;.,hrvxzThe impact was significant. Prior to this, receiving a blood transfusion was like Russian Roulette. You were receiving life saving therapy, but it coZuld also be a hidden death sentence. Now that hepatitis had been discovered, it became possible to screen patients prior to donation, to screen blood transfusion bags, and to start developing treatments for the virus.

The fight is not over yet. There are still over 70 million people who still live with the virus, and it still kills around 400,000 a year. Its only very recently that we have found treatments that can reduce the viral load in patients to levels that they are considered cured. This treatment remains expensive, and we are very far away from eradication itself.

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Busting Nutrition Myths in India: An Evidence-Based Guide Powered by SecondMedic’s AI Health Guide

Nutrition misinformation has become increasingly common in India. From viral social media diets to generational food beliefs, many individuals struggle to separate fact from fiction. These myths can influence daily habits, delay proper treatment and contribute to the growing burden of lifestyle diseases.

SecondMedic’s AI Health Guide was designed to offer clarity. By analysing scientific literature, Indian dietary patterns and personal health inputs, it explains complex nutrition topics in a human-friendly, practical manner. This blog explores the most widespread nutrition myths in India and how an AI-enabled approach helps users make informed dietary decisions.

Why Nutrition Myths Persist in India

1. Cultural dietary traditions

Food practices often evolve through experience but not always through evidence. Certain long-held assumptions continue despite scientific updates.

2. Rise of viral misinformation

Millions of Indians search diet advice online daily, and misleading content spreads rapidly without expert review.

3. High prevalence of lifestyle diseases

ICMR and NFHS-5 highlight escalating rates of:

Diabetes
Obesity
Hypertension
PCOS
Thyroid disorders

The public seeks quick solutions, making myths appealing.

4. Limited access to qualified dietitians

Many people rely on hearsay or generic tips rather than personalised nutrition guidance.

SecondMedic’s AI Health Guide bridges this gap by offering accessible, evidence-backed explanations.

Myth 1: “Carbohydrates always lead to weight gain.”

Carbohydrates are not inherently harmful.
The problem lies in refined carbohydrates like white bread, sugary drinks and packaged snacks.

What the science says

Whole grains, millets, oats and fibre-rich carbs improve:

Gut health
Blood sugar regulation
Energy levels

Research in Lancet Public Health confirms that complex carbs support metabolic wellbeing.

AI Health Guide perspective

The system evaluates:

Activity level
Blood sugar trends
Dietary preferences

Then recommends the type and quantity of carbs suitable for the individual.

Myth 2: “Protein damages the kidneys.”

This is one of India’s most common misconceptions.

Clinical reality

Protein affects kidneys only in individuals with existing kidney disease.

NFHS-5 shows that most Indians do not meet their daily protein requirement.

Balanced approach

Safe protein sources:

Lentils
Paneer
Eggs
Tofu
Chicken
Fish

An AI-guided nutrition plan ensures intake matches needs and health conditions.

Myth 3: “All fats are unhealthy.”

Fats play essential roles in:

Hormone production
Brain function
Vitamin absorption

Good fats

Nuts and seeds
Olive oil
Flaxseed
Fatty fish

Harmful fats

Trans fats
Hydrogenated oils
Deep-fried packaged snacks

SecondMedic’s AI Health Guide analyses dietary logs to suggest healthier fat alternatives.

Myth 4: “Detox diets cleanse the body.”

Detox teas, juices and cleanses are popular but not scientifically validated.

Actual detoxification

The liver, kidneys and digestive system naturally remove toxins.

Risks of extreme detox diets

Fatigue
Digestive distress
Slow metabolism
Nutrient deficiencies

A sustainable alternative includes balanced meals, hydration and fibre-rich foods.

Myth 5: “Eating after 8 PM causes weight gain.”

Timing is not the primary factor.
Weight gain depends on:

Total calorie intake
Food quality
Portion control
Sleep-wake cycles

For shift workers or late diners, an AI-based guide personalises eating windows that match biological rhythms.

How AI Personalises Nutrition Guidance for India

The AI Health Guide adapts advice based on:

• Clinical inputs

Blood reports, symptoms, chronic conditions.

• Lifestyle signals

Sleep, activity, stress, work schedules.

• Cultural eating patterns

North Indian, South Indian, vegetarian, non-vegetarian diets.

• Personal health goals

Weight control, energy improvement, disease management.

This ensures that the guidance is not generic-it is tailored for real-life Indian scenarios.

How an AI Health Guide Supports Preventive Healthcare

1. Early risk identification

AI recognises patterns that may indicate:

Rising blood sugar
Nutrient deficiencies
Poor digestion
Inflammatory markers

2. Behavioural nudges

Small, realistic changes are suggested instead of extreme diet plans.

3. Improved health literacy

Users understand why certain foods are better choices.

4. Better medical support

Clear explanations enhance doctor and dietitian consultations.

Conclusion

Nutrition myths can lead individuals toward restrictive diets, nutrient deficiencies and misguided health decisions. With rising lifestyle diseases in India, accurate nutrition knowledge is essential. A scientific, personalised approach-supported by an AI Health Guide-helps individuals navigate misinformation confidently.

By combining evidence-based insights with individual dietary needs, SecondMedic’s AI-driven guidance empowers people to adopt sustainable, preventive and truly health-enhancing food habits.

References

• ICMR Indian Nutrition Profile & Dietary Science Study
• National Family Health Survey (NFHS-5) - Protein Intake & Micronutrient Data
• NITI Aayog - Preventive Health & Digital Nutrition Insights
• WHO Global Dietary Guidelines & Balanced Nutrition Framework
• Lancet Public Health - Carbohydrate Quality & Metabolic Health Studies
• Statista - India Digital Nutrition & Health Behaviour Analysis
• EY-FICCI - AI and Preventive Healthcare Consumer Report

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