Call
+918447748545

Published on: Oct 28, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Hepatitis C Nobel Prize

Earlier this month the Nobel Prize in Physiology and Medicine was jointly awarded to Harvey J Alter, Michael Houghton and Charles M Rice for the discovery of the Hepatitis C virus. This helped push our understanding of blood-borne hepatitis, a major global health problem that is one of the leading causes of cirrhosis and liver cancer alongside Hepatitis B. It led the way in introducing new tests for chronic hepatitis as well as new treatments that have saved the lives of millions.

HEPATITIS

Hepatitis is the inflammation of your liver, the largest solid organ in your body. Though there are numerous other causes of hepatitis, including alcohol abuse, drugs and toxins (including paracetamol overdose), and autoimmune disorders (such as Wilson’s disease), viral infections are the most common worldwide causes for hepatitis. Hepatitis A was the first to be discovered, transmitted by polluted food and water, and results in a short-term transient hepatitis. Hepatitis B on the other hand is transmitted through blood and is more of an issue as it can lead to chronic cirrhosis and possible liver cancer. It can remain indolent in a person, causing disease long after the initial infection.

Blood borne hepatitis was first discovered in the 1960s, when it was found that some patients would become ill after receiving blood transfusions. Despite this discovery and new tests for Hepatitis B reducing the number of transfusion related hepatitis, a large number of cases remained.

NOT A, NOT B

Harvey Alter, working at the US National Institute of Health, was studying the occurrence of hepatitis in blood transfusion patients. His team showed that blood from these infected patients could transmit the disease to chimpanzees, resulting in hepatitis. This agent had the properties of a virus, one that was “non-A, non B” hepatitis.

Further investigation into the virus would require the input of Michael Houghton, working for Chiron pharmaceutical. His team created a collection of DNA fragments found in the blood of infected chimpanzees. Though the majority of these fragments were from the chimpanzee, enough were from the virus. They were able to utilise this information to identify antibodies against the suspected virus, and ultimately identify it as the flavivirus Hepatitis C.

The final piece of the puzzle was shown by Charles M Rice, a researcher at Washington University, St Louis – could the virus alone cause hepatitis. He studied the RNA of Hepatitis C to identify regions that may be used for replication, and areas that might hinder replication. This was key as the virus can lay dormant for years, replicating at a slow rate before causing damage to the liver. For researchers, this was an issue as it was not feasible to wait years and see if the suspected virus caused hepatitis. By genetically engineering the viral genome, he developed a variant of Hepatitis C that would only multiple rapidly and have no mechanism to inactivate itself for dormancy. This strain caused rapid changes to the livers of infected chimpanzees; the same changes seen in hepatitis patients.

. ;.,hrvxzThe impact was significant. Prior to this, receiving a blood transfusion was like Russian Roulette. You were receiving life saving therapy, but it coZuld also be a hidden death sentence. Now that hepatitis had been discovered, it became possible to screen patients prior to donation, to screen blood transfusion bags, and to start developing treatments for the virus.

The fight is not over yet. There are still over 70 million people who still live with the virus, and it still kills around 400,000 a year. Its only very recently that we have found treatments that can reduce the viral load in patients to levels that they are considered cured. This treatment remains expensive, and we are very far away from eradication itself.

Read Blog

Replace Junk with Subscription Snack Packs: A Practical Approach to Preventive Nutrition in India

India is witnessing a growing shift toward healthier eating habits, yet junk food consumption continues to rise across all age groups. According to ICMR and NFHS-5 data, high-calorie packaged snacks, sugary beverages and deep-fried foods contribute significantly to obesity, diabetes and cardiovascular risk. Replacing these items with nutritious snack alternatives is one of the simplest yet most effective steps toward preventive wellness.

Subscription snack packs offer a structured, convenient and affordable way to transition from unhealthy snacking to balanced nutrition. SecondMedic promotes this approach as part of a broader preventive health ecosystem that focuses on long-term behavioural change rather than temporary diets.

Why Indians are Choosing Healthy Snack Subscriptions

1. Convenience in fast-paced lifestyles

Urban and semi-urban households often depend on quick, accessible snacks to keep up with busy schedules. Healthy subscription packs bring pre-portioned nutrition directly to the doorstep.

2. Rising health concerns

India now ranks among the world’s highest in:

Diabetes prevalence
Childhood obesity
Hypertension
High cholesterol

Replacing junk food is essential for reducing these long-term risks.

3. Growing awareness of clean eating

People are moving toward:

Low-sugar
Low-sodium
High-fibre
High-protein
Non-fried
snack alternatives.

4. Cost-effectiveness

Contrary to belief, balanced snack packs cost less than repeated purchases of unhealthy packaged foods.

What Makes Subscription Snack Packs Healthier?

Healthy snack packs are curated for balanced nutrition:

• Nuts and seeds

Rich in healthy fats, fibre and minerals.

• Millet-based snacks

Low GI, nutrient-dense and suitable for diabetics.

• Dried fruits

Provide natural sweetness without refined sugar.

• Roasted chana and legumes

Excellent plant-based protein sources.

• Low-sugar bars

Made from oats, dates, nuts and seeds.

• Whole-grain crackers

Better than refined flour biscuits.

• Herbal teas

Support digestion and relaxation.

These snacks reduce cravings while supporting metabolic health.

Why Junk Food Needs Replacement

• High in trans fats

Linked to heart disease and inflammation.

• Excess sugar

Promotes insulin resistance, weight gain and metabolic syndrome.

• Refined flour

Lacks fibre and elevates glucose rapidly.

• Additives & preservatives

May contribute to long-term digestive and metabolic issues.

• Instant cravings

Junk foods trigger overeating by stimulating dopamine pathways.

Replacing them with healthier options breaks this cycle.

How Subscription Snack Packs Support Preventive Healthcare

1. Portion control

Pre-measured servings reduce the risk of overeating.

2. Balanced nutrition

Snack packs provide fibre, healthy fats and micronutrients missing from typical Indian diets.

3. Reduced decision fatigue

Users do not have to search for healthy options daily.

4. Behavioural consistency

Weekly or monthly packs promote long-term habit formation.

5. Support for chronic disease management

Especially helpful for:

Diabetes
PCOS
Thyroid issues
Heart disease

SecondMedic integrates snack guidance into dietitian consultations and AI-driven nutrition analysis.

The Role of AI Health Guide in Smarter Snacking

SecondMedic’s AI Health Guide provides:

• Calorie and nutrient insights

Evaluates daily intake based on user habits.

• Snack recommendations

Based on medical conditions, preferences and goals.

• Craving pattern analysis

Identifies triggers for unhealthy eating.

• Personalised preventive plans

Aligns snacking habits with heart, gut and metabolic health.

This makes snack substitution easier and more sustainable.

How to Transition from Junk Food to Healthy Snack Packs

Step 1: Identify your biggest cravings

Sugary, salty, crunchy or fried?

Step 2: Find healthier alternatives

For example:

Replace chips ? roasted makhana
Replace sweets ? dates + nuts
Replace biscuits ? whole-grain crackers

Step 3: Use subscription packs for structure

Pre-curated boxes guide behaviour change.

Step 4: Track progress

Energy levels improve within 2-4 weeks.

Step 5: Build long-term habits

Consistency leads to metabolic improvement.

Conclusion

Replacing junk food with subscription snack packs is an effective and convenient step toward preventive wellness in India. By combining healthier ingredients, balanced nutrition and consistent delivery, subscription packs help individuals make better choices daily. With expert guidance and AI-driven insights from SecondMedic, these changes become sustainable, personalised and impactful for long-term health.

References

• ICMR - Dietary Patterns & Junk Food Consumption Study
• NFHS-5 - Nutrition Deficiencies & Lifestyle Data India
• NITI Aayog - Preventive Health & Nutrition Strategy
• WHO - Healthy Diet & Non-Communicable Disease Guidelines
• Lancet - Consumption Patterns & Cardiometabolic Risk
• Statista India - Healthy Snacking Trends
• EY-FICCI - Consumer Behaviour Toward Preventive Health

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.