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Published on: Apr 06, 2020
2 minute read
By: Dr Rajan Choudhary

MicroRNA That Makes Them Fight COVID Better ?

Recently you may have read a New Delhi based International Center for Genetic Engineering and Biotechnology (ICGEB) sequenced the genome (genetic data) of SARS-COV-2 (coronavirus) from India, Italy, US, Nepal and Wuhan, China. They found that the Indian variant of SARS-CoV2 has the potential to be targeted by antiviral RNA within host cells, a feature that is unique to the Indian strain.

This amazing finding has been published on blogs, newspapers and other media as proof that Indians may not suffer as much as the rest of the world when the COVID-19 pandemic hits the country. One headline touted “MicroRNA in Indians may reduce severity of corona attack”, stating “Indians have comparatively better immunity compared to other countries”. Of course this article is being forwarded on WhatsApp, and enough people may take it as gospel. Is it true?

No.

If you want to know why, just look on the Journal’s website:

“these are preliminary reports that have not been peer-reviewed. They should NOT be regarded as conclusive, guide clinical practice/health-related behaviour, or be reported in news media as established information.”

Research is not easy. I could write a very long explanation for why, but I have summarised it below.

SUMMARY:

- To prove x causes y up to a high scientific standard is incredibly difficult

- Even if you think x causes y, someone might find a flaw in your study

- Numbers can be manipulated by statistics to show what you want to believe

- Reporters might not understand the study and mis-report it

- We all want to believe there is a magic cure that will protect us, that makes us special, immune to this disaster so we can get on with our lives. Unfortunately there simply isn’t one. And believing in them without fact checking can cause more harm than good.

IMMUNITY AGAINST COVID

So what about this study? Firstly it is looking at one tiny mechanism in a cell, when a cell can have millions of proteins responsible for a billion different functions in just the cell itself. Secondly it is not peer reviewed. This means no one has fact checked the study to check whether the design is valid, whether the statistics hold up, whether they have missed something or are making incorrect conclusions based off their data. Peer-reviewing a recent paper showing SARS-CoV-2 and HIV were extremely similar disproved this paper as false.

In the authors defence he acknowledges this:

“In our study, which is a purely computational one, we predicted that this microRNA binds to the SARS-Cov2 genome submitted from India. However, it is too early to comment on it because there is only one high coverage sequence from India, so far,”

Thirdly, the news article says that Indians have better immunity because of this “microRNA”. This is wrong. The study sequenced the genome of the virus, not of the Indian population. Antiviral microRNA is found in all people. The study simply suggests that this might be more effective at targeting the Indian strain of COVID, but it does not make any concrete claims that Indians are protected from COVID.

Again, the journal even states this:

“These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”

But most importantly, even if the paper suggests that the Indian strain may be less potent, it does not give us an excuse to be reckless. We have to adhere to social distancing, hygiene, lockdown principles in order to prevent infection. Because what happens if you take the article stating “Indians have comparatively better immunity compared to other countries” as fact, use this as an excuse to go about your regular daily lives, and it actually turns out that the microRNA has little to no effect on COVID. This endangers yourself and those around you.

Be sensible. Listen to public health officials.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Role of Nutrition in Disease Prevention: How Food Choices Shape Long-Term Health

Disease prevention is no longer limited to vaccinations and medical screenings. Modern healthcare increasingly recognises nutrition as one of the most powerful tools for preventing illness before it begins. The role of nutrition in disease prevention is especially important in India, where lifestyle-related diseases account for a large share of premature illness and mortality.

According to the Indian Council of Medical Research (ICMR) and the National Family Health Survey (NFHS-5), poor dietary patterns contribute significantly to rising cases of diabetes, heart disease, obesity and hypertension. Unlike genetic factors, nutrition is a modifiable risk factor, meaning everyday food choices can actively protect health.

Why Nutrition Is Central to Disease Prevention

1. Nutrition regulates metabolic health

Balanced diets help maintain:

healthy blood sugar levels
optimal cholesterol balance
stable blood pressure

Disruption in these systems increases disease risk.

2. Nutrition strengthens immunity

WHO highlights that immune function depends heavily on adequate intake of vitamins, minerals and protein.

3. Nutrition controls inflammation

Chronic low-grade inflammation is linked to most lifestyle diseases. Diets rich in whole foods reduce inflammatory markers.

Major Diseases Influenced by Nutrition

Diabetes and Prediabetes

Excess refined carbohydrates and sugar drive insulin resistance.

Preventive nutrition focuses on:

whole grains
fibre-rich vegetables
adequate protein
controlled portion sizes

ICMR data shows that dietary modification can delay or prevent type 2 diabetes in high-risk individuals.

Cardiovascular Disease

Heart disease remains a leading cause of death in India.

Nutrition impacts:

cholesterol levels
blood pressure
arterial inflammation

Diets low in trans fats and high in fibre significantly reduce cardiovascular risk, as confirmed by WHO and Lancet studies.

Obesity

Obesity increases the risk of multiple chronic diseases.

Preventive nutrition addresses:

calorie density
food quality
satiety regulation

NFHS-5 reports a steady rise in overweight and obesity across age groups.

Hypertension

High sodium intake and low potassium intake contribute to high blood pressure.

Preventive dietary strategies include:

reducing processed foods
increasing fruits and vegetables
maintaining mineral balance

Certain Cancers

Diet influences cancer risk through:

antioxidant intake
fibre consumption
reduced exposure to carcinogenic compounds

WHO estimates that a significant percentage of cancers are preventable through diet and lifestyle changes.

Key Nutrients That Support Disease Prevention

Fibre

Supports gut health, blood sugar control and cholesterol reduction.

Protein

Essential for muscle health, immune function and metabolic balance.

Healthy Fats

Omega-3 fats reduce inflammation and protect heart health.

Micronutrients

Iron, zinc, vitamin D and B vitamins are essential for metabolic and immune regulation.

NFHS-5 highlights widespread micronutrient deficiencies in India, increasing disease vulnerability.

Role of Gut Health in Prevention

The gut microbiome plays a major role in:

immune regulation
inflammation control
nutrient absorption

Fermented foods and fibre-rich diets support healthy gut bacteria, strengthening disease resistance.

Why Preventive Nutrition Works Best Early

Nutrition is most effective when applied:

before disease onset
during pre-disease stages
alongside regular health screening

Once disease progresses, nutrition remains supportive but may not reverse damage fully.

Nutrition vs Medication in Prevention

Medication treats disease; nutrition reduces risk.

WHO and NITI Aayog emphasize that:

preventive nutrition reduces disease incidence
lifestyle modification lowers healthcare burden
early nutrition changes reduce dependency on long-term medication

Both approaches work best when combined appropriately.

Workplace and Community Role in Preventive Nutrition

Structured nutrition programs at workplaces and communities:

improve awareness
support behaviour change
reduce population-level disease burden

Lancet studies show that group-based nutrition interventions improve long-term adherence.

Common Myths About Nutrition and Disease Prevention

Myth 1: Supplements replace healthy food

Whole foods provide better long-term protection.

Myth 2: Prevention requires extreme diets

Consistency matters more than restriction.

Myth 3: Nutrition only matters after diagnosis

Early nutrition is most effective before disease develops.

Building a Preventive Nutrition Routine

Effective preventive nutrition includes:

regular meals
diverse food groups
portion awareness
minimal processed foods
hydration

Small daily choices compound into long-term health benefits.

Long-Term Impact of Preventive Nutrition

Consistent healthy eating leads to:

reduced disease risk
improved energy and productivity
better immune resilience
lower healthcare costs
improved quality of life

NITI Aayog identifies nutrition as a cornerstone of sustainable healthcare systems.

Conclusion

Understanding the role of nutrition in disease prevention empowers individuals to take control of their health long before illness develops. Balanced, consistent nutrition reduces inflammation, supports immunity and protects against chronic diseases that burden India’s healthcare system. Preventive nutrition is not about short-term fixes but about building lifelong habits that support health, resilience and longevity.

References

ICMR – Nutrition and Lifestyle Disease Prevention Reports
National Family Health Survey (NFHS-5) – Dietary and Metabolic Health Data
NITI Aayog – Preventive Healthcare and Nutrition Strategy Reports
WHO – Diet, Nutrition and Chronic Disease Prevention Guidelines
Lancet – Nutrition and Disease Risk Reduction Studies
Statista – Dietary Trends and Health Outcomes India
EY-FICCI – Preventive Healthcare and Nutrition Economics

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