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Published on: Apr 06, 2020
2 minute read
By: Dr Rajan Choudhary

MicroRNA That Makes Them Fight COVID Better ?

Recently you may have read a New Delhi based International Center for Genetic Engineering and Biotechnology (ICGEB) sequenced the genome (genetic data) of SARS-COV-2 (coronavirus) from India, Italy, US, Nepal and Wuhan, China. They found that the Indian variant of SARS-CoV2 has the potential to be targeted by antiviral RNA within host cells, a feature that is unique to the Indian strain.

This amazing finding has been published on blogs, newspapers and other media as proof that Indians may not suffer as much as the rest of the world when the COVID-19 pandemic hits the country. One headline touted “MicroRNA in Indians may reduce severity of corona attack”, stating “Indians have comparatively better immunity compared to other countries”. Of course this article is being forwarded on WhatsApp, and enough people may take it as gospel. Is it true?

No.

If you want to know why, just look on the Journal’s website:

“these are preliminary reports that have not been peer-reviewed. They should NOT be regarded as conclusive, guide clinical practice/health-related behaviour, or be reported in news media as established information.”

Research is not easy. I could write a very long explanation for why, but I have summarised it below.

SUMMARY:

- To prove x causes y up to a high scientific standard is incredibly difficult

- Even if you think x causes y, someone might find a flaw in your study

- Numbers can be manipulated by statistics to show what you want to believe

- Reporters might not understand the study and mis-report it

- We all want to believe there is a magic cure that will protect us, that makes us special, immune to this disaster so we can get on with our lives. Unfortunately there simply isn’t one. And believing in them without fact checking can cause more harm than good.

IMMUNITY AGAINST COVID

So what about this study? Firstly it is looking at one tiny mechanism in a cell, when a cell can have millions of proteins responsible for a billion different functions in just the cell itself. Secondly it is not peer reviewed. This means no one has fact checked the study to check whether the design is valid, whether the statistics hold up, whether they have missed something or are making incorrect conclusions based off their data. Peer-reviewing a recent paper showing SARS-CoV-2 and HIV were extremely similar disproved this paper as false.

In the authors defence he acknowledges this:

“In our study, which is a purely computational one, we predicted that this microRNA binds to the SARS-Cov2 genome submitted from India. However, it is too early to comment on it because there is only one high coverage sequence from India, so far,”

Thirdly, the news article says that Indians have better immunity because of this “microRNA”. This is wrong. The study sequenced the genome of the virus, not of the Indian population. Antiviral microRNA is found in all people. The study simply suggests that this might be more effective at targeting the Indian strain of COVID, but it does not make any concrete claims that Indians are protected from COVID.

Again, the journal even states this:

“These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”

But most importantly, even if the paper suggests that the Indian strain may be less potent, it does not give us an excuse to be reckless. We have to adhere to social distancing, hygiene, lockdown principles in order to prevent infection. Because what happens if you take the article stating “Indians have comparatively better immunity compared to other countries” as fact, use this as an excuse to go about your regular daily lives, and it actually turns out that the microRNA has little to no effect on COVID. This endangers yourself and those around you.

Be sensible. Listen to public health officials.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Anemia Diet Plan: What to Eat to Improve Hemoglobin Levels Naturally

Anemia is one of the most widespread nutritional disorders in India, affecting people across age groups. According to NFHS-5 and ICMR data, more than half of Indian women and a significant proportion of men suffer from anemia. While supplements are sometimes required, a structured anemia diet plan plays a central role in preventing and managing the condition.

Anemia occurs when the body lacks sufficient healthy red blood cells or hemoglobin to carry oxygen efficiently. Nutrition is the foundation of hemoglobin production, making dietary correction essential.

Understanding the Nutritional Causes of Anemia

Anemia commonly results from deficiencies of:

iron
vitamin B12
folate

Each nutrient plays a specific role in red blood cell formation.

Iron: The Core Nutrient in Anemia

Iron is a key component of hemoglobin.

Iron deficiency leads to:

fatigue
weakness
pale skin
shortness of breath

ICMR identifies iron deficiency as the leading cause of anemia in India.

Types of Dietary Iron

Heme Iron

Found in animal foods and absorbed efficiently.

Sources include:

eggs
fish
chicken
liver

Non-Heme Iron

Found in plant-based foods and absorbed less efficiently.

Sources include:

spinach
lentils
chickpeas
jaggery
dates

Vitamin C improves non-heme iron absorption.

Role of Vitamin B12 in Anemia

Vitamin B12 is essential for red blood cell maturation.

Deficiency causes:

megaloblastic anemia
nerve symptoms
memory issues

Vegetarians are at higher risk due to limited dietary sources.

Role of Folate

Folate supports:

DNA synthesis
red blood cell formation

Low folate intake worsens anemia, especially during pregnancy.

Foods to Include in an Anemia Diet Plan

Iron-Rich Foods

green leafy vegetables (spinach, amaranth)
legumes and pulses
dates, raisins and figs
jaggery
red meat and eggs

Vitamin C-Rich Foods

citrus fruits
guava
tomatoes
bell peppers

These enhance iron absorption.

Vitamin B12 Sources

milk and dairy products
eggs
fish
fortified cereals

Folate-Rich Foods

green leafy vegetables
beans and peas
peanuts
whole grains

Sample Daily Anemia Diet Plan

Breakfast

vegetable omelette or sprouted moong
citrus fruit or guava

Mid-Morning

soaked raisins or dates
lemon water

Lunch

brown rice or roti
dal or chickpeas
green leafy vegetable sabzi
salad with lemon dressing

Evening Snack

roasted peanuts or chana
fruit rich in vitamin C

Dinner

vegetable curry with paneer or fish
whole wheat roti
lightly cooked greens

Bedtime

warm milk if tolerated

Foods That Reduce Iron Absorption

Certain foods interfere with iron absorption:

tea and coffee
excess calcium
highly processed foods

These should be avoided close to iron-rich meals.

Special Considerations for Women

Women require more iron due to:

menstruation
pregnancy
lactation

NFHS-5 highlights anemia as a major women’s health concern in India.

Anemia in Men and Older Adults

In men and elderly individuals, anemia may signal:

nutritional deficiency
chronic disease
gastrointestinal issues

Dietary correction should be combined with medical evaluation.

When Diet Alone Is Not Enough

Diet may not be sufficient if:

anemia is severe
absorption is impaired
chronic illness is present

In such cases, supplements or treatment of underlying causes is required.

Importance of Regular Blood Tests

Monitoring hemoglobin helps:

assess improvement
guide dietary adjustments
prevent recurrence

Preventive checkups are essential for high-risk groups.

Lifestyle Factors That Support Recovery

Along with diet:

adequate sleep
stress management
regular physical activity

support blood health and recovery.

Preventing Anemia Long-Term

Long-term prevention includes:

balanced meals
iron-rich cooking methods
avoiding excessive junk food
periodic screening

WHO and NITI Aayog emphasize nutrition education as a preventive strategy.

Conclusion

A well-structured anemia diet plan is the cornerstone of improving hemoglobin levels and restoring energy. By including iron-rich foods, supporting nutrients like vitamin B12 and folate, and improving absorption through smart food combinations, anemia can be effectively managed and prevented. Early dietary intervention, supported by regular health monitoring, helps avoid long-term complications and improves overall quality of life.

References

Indian Council of Medical Research (ICMR) – Anemia and Micronutrient Deficiency Reports
National Family Health Survey (NFHS-5) – Anemia Prevalence Data
World Health Organization (WHO) – Nutrition and Anemia Guidelines
Lancet – Micronutrient Deficiency and Public Health Research
NITI Aayog – Poshan Abhiyaan and Nutrition Policy Reports
Statista – Nutrition and Health Trends in India

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