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Published on: Apr 06, 2020
2 minute read
By: Dr Rajan Choudhary

MicroRNA That Makes Them Fight COVID Better ?

Recently you may have read a New Delhi based International Center for Genetic Engineering and Biotechnology (ICGEB) sequenced the genome (genetic data) of SARS-COV-2 (coronavirus) from India, Italy, US, Nepal and Wuhan, China. They found that the Indian variant of SARS-CoV2 has the potential to be targeted by antiviral RNA within host cells, a feature that is unique to the Indian strain.

This amazing finding has been published on blogs, newspapers and other media as proof that Indians may not suffer as much as the rest of the world when the COVID-19 pandemic hits the country. One headline touted “MicroRNA in Indians may reduce severity of corona attack”, stating “Indians have comparatively better immunity compared to other countries”. Of course this article is being forwarded on WhatsApp, and enough people may take it as gospel. Is it true?

No.

If you want to know why, just look on the Journal’s website:

“these are preliminary reports that have not been peer-reviewed. They should NOT be regarded as conclusive, guide clinical practice/health-related behaviour, or be reported in news media as established information.”

Research is not easy. I could write a very long explanation for why, but I have summarised it below.

SUMMARY:

- To prove x causes y up to a high scientific standard is incredibly difficult

- Even if you think x causes y, someone might find a flaw in your study

- Numbers can be manipulated by statistics to show what you want to believe

- Reporters might not understand the study and mis-report it

- We all want to believe there is a magic cure that will protect us, that makes us special, immune to this disaster so we can get on with our lives. Unfortunately there simply isn’t one. And believing in them without fact checking can cause more harm than good.

IMMUNITY AGAINST COVID

So what about this study? Firstly it is looking at one tiny mechanism in a cell, when a cell can have millions of proteins responsible for a billion different functions in just the cell itself. Secondly it is not peer reviewed. This means no one has fact checked the study to check whether the design is valid, whether the statistics hold up, whether they have missed something or are making incorrect conclusions based off their data. Peer-reviewing a recent paper showing SARS-CoV-2 and HIV were extremely similar disproved this paper as false.

In the authors defence he acknowledges this:

“In our study, which is a purely computational one, we predicted that this microRNA binds to the SARS-Cov2 genome submitted from India. However, it is too early to comment on it because there is only one high coverage sequence from India, so far,”

Thirdly, the news article says that Indians have better immunity because of this “microRNA”. This is wrong. The study sequenced the genome of the virus, not of the Indian population. Antiviral microRNA is found in all people. The study simply suggests that this might be more effective at targeting the Indian strain of COVID, but it does not make any concrete claims that Indians are protected from COVID.

Again, the journal even states this:

“These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”

But most importantly, even if the paper suggests that the Indian strain may be less potent, it does not give us an excuse to be reckless. We have to adhere to social distancing, hygiene, lockdown principles in order to prevent infection. Because what happens if you take the article stating “Indians have comparatively better immunity compared to other countries” as fact, use this as an excuse to go about your regular daily lives, and it actually turns out that the microRNA has little to no effect on COVID. This endangers yourself and those around you.

Be sensible. Listen to public health officials.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Monthly Health Survey via SecondMedic App: A Smarter Approach to Preventive Healthcare

Healthcare is gradually shifting from reactive treatment to proactive prevention. Traditional health models rely heavily on annual checkups or medical visits only after symptoms become severe. However, many chronic and lifestyle-related conditions develop silently over time. The Monthly Health Survey via the SecondMedic App addresses this gap by enabling continuous health monitoring and early risk identification.

According to the Indian Council of Medical Research (ICMR) and NITI Aayog, early detection and preventive care are critical to reducing the growing burden of non-communicable diseases in India. Digital health tools play a key role in achieving this shift.

What Is the Monthly Health Survey?

The Monthly Health Survey is a structured digital questionnaire delivered through the SecondMedic App. It captures key health indicators such as:

recurring symptoms
lifestyle habits
stress and sleep patterns
nutrition and activity levels
chronic condition markers

By repeating the survey monthly, subtle health trends become visible.

Why Monthly Health Tracking Matters

Annual Checkups Miss Gradual Changes

Many health issues develop slowly. Annual tests may appear normal while symptoms quietly progress between visits.

Monthly surveys:

detect early warning signs
capture symptom patterns
identify lifestyle-related risks

Health Is Dynamic, Not Static

Stress, sleep, diet and activity fluctuate monthly. Regular tracking reflects real-life health variation more accurately than isolated tests.

How the Monthly Health Survey Works

Each month, users answer a guided set of questions related to:

physical symptoms
mental wellbeing
lifestyle behaviours
known medical conditions

The app analyses responses to highlight:

risk trends
symptom persistence
areas needing attention

This structured approach simplifies health awareness.

Key Health Areas Covered

Symptom Monitoring

Persistent fatigue, headaches, breathlessness or digestive issues are tracked across months to identify patterns.

Lifestyle Risk Factors

The survey captures:

sedentary behaviour
sleep quality
stress levels
dietary habits

These factors strongly influence long-term health outcomes.

Chronic Disease Indicators

For individuals with diabetes, hypertension or thyroid conditions, monthly monitoring supports better disease control and early escalation.

Role in Preventive Healthcare

Preventive healthcare focuses on stopping disease before complications arise.

Monthly health surveys support prevention by:

identifying risks early
prompting timely consultations
supporting lifestyle modification
reducing emergency care needs

WHO and NITI Aayog both highlight digital monitoring as a cornerstone of preventive health systems.

Benefits for Individuals

Early Awareness

Users become aware of health changes before symptoms become severe.

Empowered Decision-Making

Access to regular health insights encourages proactive lifestyle choices.

Reduced Anxiety

Structured tracking reduces uncertainty and fear about unexplained symptoms.

Better Doctor Consultations

Survey data provides doctors with a clearer health history, improving consultation quality.

Benefits for Chronic Care Management

For chronic conditions, consistency is key.

Monthly surveys help:

track symptom control
identify early deterioration
support medication adherence
reduce complications

This continuous loop improves long-term outcomes.

Data-Driven Personalised Care

The survey supports personalised care by:

tailoring recommendations
prioritising high-risk users
guiding preventive interventions

This approach moves healthcare from generic advice to individualised guidance.

Privacy and Responsible Use

Health data is sensitive.

The survey framework is designed to:

collect only relevant information
support medical decision-making
maintain confidentiality

Responsible data use builds trust and long-term engagement.

Why Digital Surveys Are Effective in India

India’s healthcare challenges include:

large population
limited access to preventive care
high lifestyle disease burden

Digital surveys overcome barriers by:

being accessible anywhere
requiring minimal time
enabling large-scale preventive monitoring

This scalability makes them highly impactful.

Integration with Broader Health Ecosystems

Monthly health surveys work best when integrated with:

medical consultations
diagnostic services
preventive checkups
digital health records

Integration ensures continuity of care.

Long-Term Impact on Healthcare Outcomes

Over time, regular health tracking leads to:

earlier diagnoses
reduced hospitalisations
better chronic disease control
lower healthcare costs
improved quality of life

Lancet studies show that continuous monitoring significantly improves preventive outcomes.

Who Should Use a Monthly Health Survey?

adults over 30
individuals with chronic conditions
people with high-stress lifestyles
those focusing on preventive health
corporate wellness participants

Proactive monitoring benefits all age groups.

Conclusion

The Monthly Health Survey via the SecondMedic App represents a modern, preventive approach to healthcare. By capturing health trends regularly rather than annually, it empowers individuals to act early, supports doctors with better insights and reduces the burden of advanced disease. In an era where prevention is the most effective medicine, monthly health surveys transform awareness into action and data into healthier lives.

References

Indian Council of Medical Research (ICMR) – Preventive Healthcare and Early Detection Report
NITI Aayog – Digital Health and Preventive Care Strateg
World Health Organization (WHO) – Digital Health Monitoring Guideline
Lancet – Preventive Healthcare and Continuous Monitoring Studies
National Health Authority – Digital Health Mission Indi
Statista – Digital Health App Adoption Trends India

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