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Published on: Apr 06, 2020
2 minute read
By: Dr Rajan Choudhary

MicroRNA That Makes Them Fight COVID Better ?

Recently you may have read a New Delhi based International Center for Genetic Engineering and Biotechnology (ICGEB) sequenced the genome (genetic data) of SARS-COV-2 (coronavirus) from India, Italy, US, Nepal and Wuhan, China. They found that the Indian variant of SARS-CoV2 has the potential to be targeted by antiviral RNA within host cells, a feature that is unique to the Indian strain.

This amazing finding has been published on blogs, newspapers and other media as proof that Indians may not suffer as much as the rest of the world when the COVID-19 pandemic hits the country. One headline touted “MicroRNA in Indians may reduce severity of corona attack”, stating “Indians have comparatively better immunity compared to other countries”. Of course this article is being forwarded on WhatsApp, and enough people may take it as gospel. Is it true?

No.

If you want to know why, just look on the Journal’s website:

“these are preliminary reports that have not been peer-reviewed. They should NOT be regarded as conclusive, guide clinical practice/health-related behaviour, or be reported in news media as established information.”

Research is not easy. I could write a very long explanation for why, but I have summarised it below.

SUMMARY:

- To prove x causes y up to a high scientific standard is incredibly difficult

- Even if you think x causes y, someone might find a flaw in your study

- Numbers can be manipulated by statistics to show what you want to believe

- Reporters might not understand the study and mis-report it

- We all want to believe there is a magic cure that will protect us, that makes us special, immune to this disaster so we can get on with our lives. Unfortunately there simply isn’t one. And believing in them without fact checking can cause more harm than good.

IMMUNITY AGAINST COVID

So what about this study? Firstly it is looking at one tiny mechanism in a cell, when a cell can have millions of proteins responsible for a billion different functions in just the cell itself. Secondly it is not peer reviewed. This means no one has fact checked the study to check whether the design is valid, whether the statistics hold up, whether they have missed something or are making incorrect conclusions based off their data. Peer-reviewing a recent paper showing SARS-CoV-2 and HIV were extremely similar disproved this paper as false.

In the authors defence he acknowledges this:

“In our study, which is a purely computational one, we predicted that this microRNA binds to the SARS-Cov2 genome submitted from India. However, it is too early to comment on it because there is only one high coverage sequence from India, so far,”

Thirdly, the news article says that Indians have better immunity because of this “microRNA”. This is wrong. The study sequenced the genome of the virus, not of the Indian population. Antiviral microRNA is found in all people. The study simply suggests that this might be more effective at targeting the Indian strain of COVID, but it does not make any concrete claims that Indians are protected from COVID.

Again, the journal even states this:

“These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”

But most importantly, even if the paper suggests that the Indian strain may be less potent, it does not give us an excuse to be reckless. We have to adhere to social distancing, hygiene, lockdown principles in order to prevent infection. Because what happens if you take the article stating “Indians have comparatively better immunity compared to other countries” as fact, use this as an excuse to go about your regular daily lives, and it actually turns out that the microRNA has little to no effect on COVID. This endangers yourself and those around you.

Be sensible. Listen to public health officials.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Lifestyle Disease Prevention India: Protecting Health Through Proactive Care

Lifestyle diseases, also known as non-communicable diseases (NCDs), have become one of India’s most pressing health challenges. Conditions such as diabetes, hypertension, obesity, heart disease, thyroid disorders, fatty liver, and high cholesterol now affect millions-often starting at younger ages compared to previous generations. According to the Indian Council of Medical Research (ICMR), NCDs account for more than 60 percent of deaths in India. The good news: most lifestyle diseases are preventable with awareness, screening, and timely intervention.

SecondMedic supports a national shift from reactive to preventive healthcare through early detection, nutrition planning, lifestyle improvement, and chronic risk monitoring.

Why Lifestyle Disease Prevention Matters in India

1. Rising NCD Burden

Rapid urbanization, longer working hours, stress, and processed foods have accelerated lifestyle disease growth.

2. Younger Population at Risk

More Indians in their 20s and 30s are developing prediabetes, fatty liver, and high cholesterol.

3. Silent Disease Progression

Many conditions show no symptoms in the early stages.

4. High Long-Term Medical Cost

Treatment for advanced diabetes or heart disease is expensive compared to prevention.

5. Impact on Productivity

Organizations face rising health-related absenteeism and reduced performance.

Prevention is not optional-it is a necessity.

Major Lifestyle Diseases in India

1. Diabetes & Prediabetes

India has over 10 crore diabetics, with many unaware of their condition.

2. Hypertension

Known as the “silent killer,” it increases risk for heart attack and stroke.

3. Heart Disease

India sees one of the highest premature heart attack rates globally.

4. Obesity & Metabolic Syndrome

Poor diet and inactivity contribute to dangerous fat accumulation.

5. Fatty Liver Disease

Highly common even among non-alcoholic individuals.

6. Thyroid Disorders

Thyroid imbalances affect metabolism, weight, and mental health.

7. Stress & Sleep Disorders

Impact emotional stability and long-term health.

SecondMedic offers preventive screenings tailored for each of these risk areas.

Early Detection Through Preventive Health Checkups

Preventive checkups help detect abnormalities before they turn into chronic disease.

SecondMedic’s packages include:

CBC
Lipid profile
HbA1c
Thyroid panel
Liver function tests
Kidney profile
Cardiac markers
Vitamin D & B12
Hormone tests
ECG

These tests provide a comprehensive health snapshot.

Lifestyle Disease Prevention Strategies

1. Nutrition Management

A healthy diet is the foundation of prevention.
SecondMedic dietitians design personalized nutrition plans based on:

Age
Weight
Activity
Medical history

2. Regular Physical Activity

Movement reduces blood sugar, strengthens the heart, and improves metabolism.

3. Stress Management

Chronic stress increases cortisol, causing diabetes and weight gain.
SecondMedic offers:

Online mental health counselling
Anxiety management
Sleep routines

4. Avoiding Tobacco & Alcohol

These significantly increase risk of cancer, fatty liver, and heart disease.

5. Healthy Weight Maintenance

Targeted routines help maintain optimal BMI and waist circumference.

6. Adequate Sleep

Poor sleep leads to hormonal imbalance and weak immunity.

7. Regular Health Checkups

Monitoring every 6-12 months helps track changes early.

Technology in Lifestyle Disease Prevention

India’s digital health ecosystem supports smarter prevention through:

Wearables
Fitness trackers
AI-based risk prediction
Digital symptom assessment
Remote monitoring devices

SecondMedic integrates these tools for continuous care.

Why SecondMedic for Lifestyle Disease Prevention

1. Comprehensive Screening

All major biomarkers, organ function tests, and metabolic indicators.

2. Expert Interpretation

Doctors analyze results and provide actionable insights.

3. Personalized Health Plans

Nutrition + fitness + lifestyle guidance.

4. Continuous Monitoring

Follow-ups ensure long-term success.

5. Integrated Telemedicine Support

Patients can speak to specialists anytime.

Conclusion

Lifestyle disease prevention India is crucial for improving long-term health and reducing the national burden of chronic diseases. Through early screening, targeted intervention, better nutrition, exercise routines, and continuous monitoring, individuals can dramatically reduce their risk. SecondMedic offers a complete ecosystem of preventive healthcare to help Indians stay healthy and proactive.

To begin your preventive health journey, visit www.secondmedic.com

References

ICMR - India NCD burden
WHO - Global NCD prevention guidelines
Statista - Lifestyle disease trends in India
NITI Aayog - Preventive health model
SecondMedic preventive care insights

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