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Published on: Apr 06, 2020
2 minute read
By: Dr Rajan Choudhary

MicroRNA That Makes Them Fight COVID Better ?

Recently you may have read a New Delhi based International Center for Genetic Engineering and Biotechnology (ICGEB) sequenced the genome (genetic data) of SARS-COV-2 (coronavirus) from India, Italy, US, Nepal and Wuhan, China. They found that the Indian variant of SARS-CoV2 has the potential to be targeted by antiviral RNA within host cells, a feature that is unique to the Indian strain.

This amazing finding has been published on blogs, newspapers and other media as proof that Indians may not suffer as much as the rest of the world when the COVID-19 pandemic hits the country. One headline touted “MicroRNA in Indians may reduce severity of corona attack”, stating “Indians have comparatively better immunity compared to other countries”. Of course this article is being forwarded on WhatsApp, and enough people may take it as gospel. Is it true?

No.

If you want to know why, just look on the Journal’s website:

“these are preliminary reports that have not been peer-reviewed. They should NOT be regarded as conclusive, guide clinical practice/health-related behaviour, or be reported in news media as established information.”

Research is not easy. I could write a very long explanation for why, but I have summarised it below.

SUMMARY:

- To prove x causes y up to a high scientific standard is incredibly difficult

- Even if you think x causes y, someone might find a flaw in your study

- Numbers can be manipulated by statistics to show what you want to believe

- Reporters might not understand the study and mis-report it

- We all want to believe there is a magic cure that will protect us, that makes us special, immune to this disaster so we can get on with our lives. Unfortunately there simply isn’t one. And believing in them without fact checking can cause more harm than good.

IMMUNITY AGAINST COVID

So what about this study? Firstly it is looking at one tiny mechanism in a cell, when a cell can have millions of proteins responsible for a billion different functions in just the cell itself. Secondly it is not peer reviewed. This means no one has fact checked the study to check whether the design is valid, whether the statistics hold up, whether they have missed something or are making incorrect conclusions based off their data. Peer-reviewing a recent paper showing SARS-CoV-2 and HIV were extremely similar disproved this paper as false.

In the authors defence he acknowledges this:

“In our study, which is a purely computational one, we predicted that this microRNA binds to the SARS-Cov2 genome submitted from India. However, it is too early to comment on it because there is only one high coverage sequence from India, so far,”

Thirdly, the news article says that Indians have better immunity because of this “microRNA”. This is wrong. The study sequenced the genome of the virus, not of the Indian population. Antiviral microRNA is found in all people. The study simply suggests that this might be more effective at targeting the Indian strain of COVID, but it does not make any concrete claims that Indians are protected from COVID.

Again, the journal even states this:

“These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”

But most importantly, even if the paper suggests that the Indian strain may be less potent, it does not give us an excuse to be reckless. We have to adhere to social distancing, hygiene, lockdown principles in order to prevent infection. Because what happens if you take the article stating “Indians have comparatively better immunity compared to other countries” as fact, use this as an excuse to go about your regular daily lives, and it actually turns out that the microRNA has little to no effect on COVID. This endangers yourself and those around you.

Be sensible. Listen to public health officials.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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5K Run for a Cause: How Community Fitness Drives Preventive Health Awareness

Physical activity is one of the most effective tools for disease prevention, yet it remains underutilised in everyday life. Community-based fitness initiatives such as a 5K Run for a Cause play a powerful role in bridging this gap by making movement accessible, meaningful and socially engaging. These events combine the benefits of exercise with awareness-building, creating lasting impact on public health.

In India, lifestyle-related diseases such as diabetes, heart disease and obesity are rising rapidly. According to the Indian Council of Medical Research (ICMR) and National Family Health Survey (NFHS-5), physical inactivity is a major contributor to this growing burden. Events that encourage structured, enjoyable physical activity help counter this trend.

What Is a 5K Run for a Cause?

A 5K Run for a Cause is a short-distance running or walking event designed to promote fitness while supporting a health, social or community objective. Participants may run, jog or walk the 5-kilometre distance, making the event inclusive for people of varying fitness levels.

Beyond physical activity, these runs aim to:

raise awareness about preventive health
encourage active lifestyles
build community participation
support wellness-driven causes

Why 5K Is an Ideal Distance

The 5-kilometre distance is widely recognised as:

achievable for beginners
challenging enough to promote fitness
safe for most age groups with minimal training

WHO physical activity guidelines support moderate-intensity exercise like running or brisk walking for improving cardiovascular and metabolic health.

Health Benefits of Participating in a 5K Run

Improved Cardiovascular Health

Running and brisk walking strengthen the heart, improve circulation and lower blood pressure. Regular participation reduces the risk of heart disease and stroke.

Better Metabolic Health

Physical activity improves insulin sensitivity and supports weight management. ICMR data shows that regular movement significantly reduces diabetes risk.

Enhanced Mental Wellbeing

Exercise releases endorphins that reduce stress, anxiety and depression. Community runs add a social element that further supports mental health.

Improved Musculoskeletal Strength

Running strengthens muscles, bones and joints, reducing the risk of age-related mobility issues.

Role of 5K Runs in Preventive Healthcare

Preventive healthcare focuses on reducing disease risk before illness develops. A 5K Run for a Cause supports prevention by:

promoting physical activity
encouraging regular movement habits
raising awareness about lifestyle diseases
motivating health-conscious behaviour

NITI Aayog identifies physical activity promotion as a key pillar of preventive healthcare in India.

Community Impact of a 5K Run for a Cause

Building Health Awareness

Runs often highlight specific causes such as heart health, diabetes prevention or mental wellbeing, reinforcing public health messages.

Strengthening Social Bonds

Community participation fosters shared goals and mutual motivation, increasing long-term adherence to healthy habits.

Encouraging Family Participation

Inclusive events encourage families to adopt healthier lifestyles together.

5K Runs and Corporate Wellness Programs

Corporate wellness programs increasingly include physical activity initiatives.

Benefits for organisations include:

improved employee engagement
reduced absenteeism
enhanced team bonding
positive employer branding

EY-FICCI reports show that wellness initiatives focused on physical activity deliver strong participation and measurable health benefits.

Accessibility and Inclusivity

A key strength of 5K runs is inclusivity.

They accommodate:

first-time runners
walkers
older adults
people transitioning to active lifestyles

This inclusiveness reduces barriers to participation.

Supporting Long-Term Behaviour Change

One-time events create awareness, but their true value lies in inspiring long-term change.

Participants often:

continue walking or running regularly
become more conscious of fitness
seek preventive health checkups

Lancet studies indicate that community-based physical activity initiatives can influence long-term health behaviours.

Safety and Health Considerations

For safe participation:

individuals should assess fitness levels
warm-up and cool-down are essential
hydration should be prioritised
those with medical conditions should seek medical advice

Proper guidance ensures benefits without injury.

Role of Awareness and Education

Successful runs integrate education through:

health talks
informational materials
screening camps
wellness resources

This combination reinforces preventive health messages.

Measuring Impact

Impact can be assessed through:

participation rates
follow-up health initiatives
employee engagement metrics
community feedback

Data-driven evaluation improves future program design.

Why 5K Runs Matter in India

India faces challenges such as:

rising sedentary lifestyles
limited health awareness
increasing chronic disease burden

Community fitness events provide a scalable, low-cost solution to promote active living and prevention.

Conclusion

A 5K Run for a Cause is more than a fitness event—it is a preventive health movement. By combining physical activity with purpose, these runs encourage healthier lifestyles, strengthen community bonds and raise awareness about long-term wellbeing. In a country where lifestyle diseases are growing rapidly, initiatives that make movement accessible and meaningful are essential. A simple 5K run can be a powerful step toward a healthier, more active society.

References

ICMR – Physical Activity and Lifestyle Disease Prevention Reports
National Family Health Survey (NFHS-5) – Physical Activity and Health Data
NITI Aayog – Preventive Healthcare and Physical Activity Promotion Strategy
WHO – Physical Activity and Health Guideline
Lancet – Community Fitness and Preventive Health Studies
Statista – Fitness Events and Participation Trends India
EY-FICCI – Corporate Wellness and Physical Activity Reports

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