• Published on: Sep 12, 2021
  • 6 minute read
  • By: Dr Rakesh Rai

Diagnostics : When Doctors Recommend It

  • WhatsApp share link icon
  • copy & share link icon
  • twitter share link icon
  • facebook share link icon

Diagnostics  : Understanding PET Scan – When doctors recommend it & what are the disadvantages if any.

Why would a doctor recommend a PET scan

A PET scan is an imaging study that produces clearer, more detailed information about the body, especially when looking for disease. The most common PET scans are used to diagnose cancers and show tissue changes in different parts of the body such as lungs or kidneys.

A PET scan is often done if a patient is having symptoms like confusion, sudden weight loss, and vomiting. These symptoms can be signs of cancer but they can also be caused by other diseases like ulcers/peptic ulcer disease (indigestion), low blood sugar (diabetes), and chronic kidney or liver failure. A doctor will recommend a PET scan if these symptoms last longer than three months in order to find out what may be causing them.

The PET scan is recommended for many cancers to determine the viability of chemotherapy treatments, which can be too harsh for people with low levels of glucose in their cells.

Positron-emitting radioactive tracers like fluorodeoxyglucose (FDG) are used to label and identify tissues in organs in your body. The concentration FDG labeled products in a particular organ will show how active that organ is functioning in the body. For example, when cancer cells are active there is often an increased uptake FDG inside these cells (a person's cancerous tumor). With this information, doctors may recommend lower doses of chemotherapy which can be more tolerable for patients who have low blood glucose levels.

A PET scan can help a physician diagnose a variety of conditions, including lung/liver disease, cancer problems, coronary artery disease and stroke. It's also used to assess radiation exposure or detect physical injuries.

Modern nuclear medicine techniques use short-lived radioactive molecules called radioisotopes that are injected into the body to provide information about function in specific organs or tissues. The radioisotope is usually combined with an accompanying medication that is being tested for the problem being studied. In some cases, a not-radioactive compound can be inserted into a vein to produce an image like what will be seen in a PET scan in another laboratory without exposing patients to any radiation at all.

A doctor typically recommends a PET scan for any change in an individual's physical or mental health. A PET scan helps doctors diagnose cancers, neurological diseases, heart disease, lung disease, liver disease, and more. The test can be done at the same time as other tests that are already planned to be taken place, or it can be done on its own without warning.

A PET scan is recommended when the diagnosis of carcinoma, sarcoma or leukemia is uncertain, given atypical findings on any imaging exam done on the individual's digestive organs. PET scans are usually used on individuals with unexplained gastrointestinal issues.

Positron emission tomography (PET), sometimes called single-photon emission computed tomography (SPECT) involves using gamma rays that pass through tissue and collide with electrons in different tissues to create positrons and then capture these emitted positrons on a camera that uses very sensitive light detectors or semiconductor detectors to detect their energy or direction of motion after ionization from their initial collision.

Positron Emission Tomography (PET) is a nuclear medicine imaging technique used to detect shape and location of functional tracer in the body. It involves using molecular scans to produce 3D images that doctors can use to diagnose illness and any changes in the affected area. PET scans use low doses of radiation that's delivered to an invasive and targeted area within your body by a cyclotron (a device like a medical x-ray tube). These low doses might be used as little as two times every year, if you have been hospitalized for heart bypass surgery or other open-heart procedure OR used before many types of cancer treatments so as to find how close as possible, they are coming.

PET scans are used for a variety of reasons, but these are the most common applications: -

  • Diagnosing cancer or other metabolic disorders   - Finding out where a contrast dye is leaking into the tissues (e.g., diverticulitis)   - Tumor staging (e.g., glioblastoma)
  • Planning lung surgery (lung CT planning) for central airway obstruction (RV typically needs to be reamed out to make it wider at the surgical site; large TVS may need to be lobe amputated; viable transplant option is latissumus dorsi flap instead)- Evaluating "restrictive" affections of chest wall & lungs like neuroma

The PET scan will help to rule out any form of cancerous cells in the body and will also detect damage to the brain caused by Alzheimer's disease. It can't properly diagnose Alzheimer's itself but it can pinpoint its progression better than other methods. Doctors ask people to take this test when they are concerned about memory loss or dementia which may indicate an early case of Alzheimer's. The doctor also asks them to look through medical records because sometimes there may be clues that trigger his anxieties like drug reactions, alcoholism, endocrine disorders; multiple sclerosis; seizure disorders; strong depressive states or strong anxiogenic states.

Positrons are emitted by the radioisotope that has been injected into the patient just before the imaging part of the procedure starts. Positrons are identical except that they have an electric charge, while electrons have a negative charge. The scanner’s detector records all "positive" positron energetic events in order to create computerized images of body structures and organs. Additionally, because not all positrons emitted by radioactive material collide with another electron or other particle, some positrons during their brief life-span (10-15 seconds)

Is a PET scan claustrophobic?\

Upon entering the machine, a patient is instructed to lie down on his or her back while sliding into a cylindrical opening in one of the walls. The person may be enclosed by anything from a simple mesh barrier to a thick fiberglass shell giving direct access only to their head and neck.

It's possible for some patients, depending on size and shape, that would not feel claustrophobic. For most patients, though it is normal that they would at least feel anxious, frightened, or nervous when seeing no exit from the machine except through the way they came in—this feeling goes away with time as you're more accustomed to being inside.

It shouldn't be, as the CT scan machine moves around you to take a series of scans from different angles. Information to include in the answer: Requires that you drink a liter of water beforehand and burp every few hours afterward.

Your comfort during a PET scan will depend largely on your tolerance to being closed-in places. It can be intimidating and scary for those who don't like tightly enclosed spaces, even if the space is relatively large such as an MRI or CT scanner. Those who are feeling uneasy should speak with their physician before proceeding with the test.

What are the disadvantages of a PET scan?

From a medical perspective, some disadvantages of PET scans include radiation exposure as well as increased sensitivity to false positives.

PET scans can expose our bodies to various types of radiation from the radioactive substances injected into the body during the procedure. These substances will decay and emit ionizing radiation at a rate greater than that emitted by ordinary atmospheric radon leading to pet scans being more sensitive for false positives than other scans. However, it does not significantly increase your risk for developing cancer later in life these risks are very low.

This means that when doctors use this type of scan to diagnose patients, they can expect more accurate results than with other types of scans like CT (although there is still some work left to be done)

The sugar solution used in the PET scan emits low levels of radiation which does not harm the cells of your body. Your doctor directs these rays where needed without risking any harm on you or their own health. The increased cost of the procedure due to high demand and technological excellence. 

A PET scan can be a redundant test, due to the low sensitivity of the scanning equipment.

A PET scan is made up of many radio buttons that emit photons into your body and then measure what they interact with after it passes through you. However, there are often places in the body where something gets inserted during an IV infusion for example, which can't be detected by a PET scan - yet this spot will show up as an abnormality on a CT or MRI. So a doctor may choose to do another imaging study instead of a PET scan. Also, because all tissues appear bright on these scans (e.g., stomach containing food appears bright), some doctors think it interferes with true diagnoses to make tissue distinctions difficult

It's possible to see cancerous cells too small to be detected

A PET scan can also create a false-positive result from substances such as amyloid protein, which is associated with Alzheimer's disease. In addition, the injections used to inject patients for a PET scan may cause minor allergic reactions in some patients. In rare cases, these reactions have been fatal.

The scans emit radiation which can damage cells in the long run. There is also speculation about whether the use of the more powerful alpha-emitting particles associated with radiolabeling leads to an increase in cancer risk. It has been estimated that these potential risks may be acceptable in a small proportion of cases where there is a good chance that this imaging procedure could save a person's life or improve their health. Still, many physicians would prefer to avoid using PET scans if possible, without compromising patient care by not ordering appropriate tests to diagnose serious illnesses when needed.

In most cases, a PET scan has no disadvantages, since it doesn't have an ionizing radiation dose.

The disadvantage to a PET scan is that they are not as accurate as a CT or MRI. A person can "clear" their chest of cancer cells so the doctor gets a false negative on the PET scans which leads to them recommending immediate surgery. The patient's surgeon can easily know if this is going to happen by looking at the mass and taking a biopsy for confirmation--most often before surgery (even if it will be after surgery). So there is no reason not to do both unless tumors are small and tumors cannot clearly be seen on an initial evaluation with ultrasound or MRI imaging techniques. This article goes into more

Well, the most obvious disadvantage of a PET scan is that it has to be taken very close to an x-ray (or other radioactive material) source. This means the room needs to be isolated from outside sources of radiation, which can prove more difficult than with other scanning procedures.

It also involves greater risk because there is no detector or shield on the head for this procedure - unlike in CT scanning - so some radiation just shoots straight up into your skull. Finally, there's a higher cost associated with it as well.

It can be uncomfortable to sit with your head inside of this scanner, but there are usually plenty of people around you the entire time that offer support. It's like always having someone behind you - making sure that they're there if something goes wrong and they'll hold my hand if it gets worse. It feels like I'm not alone; someone is bringing me back up when I get scared or upset.  My safety net is one step closer than they would normally be by my side for any other sort of medical procedure too - they can make sure that everything is going well before moving on to the next thing if anything goes wrong, which means that I don't have to worry as much about being safe."

Read Blog
Air Pollution & Respiratory Health

Air Pollution & Respiratory Health: Understanding the Impact and Taking Action

Introduction

Air pollution has become a growing concern in India, especially in urban and industrial areas. One of the most serious effects of air pollution is its impact on respiratory health. As pollution levels continue to rise, it’s important for people to understand how polluted air affects their lungs and overall breathing. This blog will explain what air pollution is, how it harms the respiratory system, and what steps you can take to protect yourself and your loved ones.

 

What is Air Pollution?

Air pollution is the presence of harmful substances in the air that we breathe. These substances, known as pollutants, can come from both natural and man-made sources. The major air pollutants include:

  • Particulate Matter (PM2.5 and PM10) – Tiny particles from vehicles, factories, and construction that can enter the lungs.
     

  • Carbon Monoxide (CO) – A colorless gas produced by burning fuel.
     

  • Nitrogen Dioxide (NO?) – Released from vehicle exhaust and industrial activities.
     

  • Sulfur Dioxide (SO?) – Mainly from burning coal and oil.
     

  • Ozone (O?) – A gas that forms when sunlight reacts with pollutants.
     

These pollutants are invisible but have a big impact on our health, especially when inhaled over long periods.

 

Sources of Air Pollution in India

In India, air pollution comes from a variety of sources:

  • Vehicle emissions – The rising number of cars and bikes contribute heavily to pollution, especially in cities.
     

  • Industrial discharge – Factories and power plants release gases and smoke into the air.
     

  • Construction dust – Rapid urban development leads to dust and debris in the air.
     

  • Burning of biomass – In rural areas, wood, dung, and crop residues are often burned for cooking or heating.
     

  • Stubble burning – Common in northern states during harvest seasons.
     

  • Household emissions – Use of traditional stoves and fuels in homes adds to indoor pollution.
     

Together, these factors make the air in many Indian cities dangerous to breathe.

 

How Air Pollution Affects Respiratory Health

The respiratory system includes the nose, throat, windpipe, and lungs. When we breathe in polluted air, harmful particles and gases enter the body and cause a number of problems:

1. Asthma

Pollution can trigger asthma attacks or make existing asthma worse. It causes inflammation in the airways, making it hard to breathe.

2. Chronic Obstructive Pulmonary Disease (COPD)

This includes long-term conditions like chronic bronchitis and emphysema. Exposure to polluted air over time is a major risk factor for COPD.

3. Lung Cancer

Long-term exposure to fine particulate matter (PM2.5) increases the risk of developing lung cancer, even in people who don’t smoke.

4. Respiratory Infections

Children and elderly people are especially prone to infections like pneumonia and bronchitis when the air is polluted.

5. Worsening of Existing Conditions

For people already suffering from respiratory diseases, poor air quality can lead to more frequent doctor visits and hospitalizations.

 

Who is Most at Risk?

While air pollution affects everyone, some people are more vulnerable:

  • Children – Their lungs are still developing, and they breathe faster, which means they inhale more pollutants.
     

  • Elderly people – They often have weaker immune systems and pre-existing health problems.
     

  • People with lung or heart conditions – They may suffer more severely from pollution.
     

  • Outdoor workers – People like traffic police, street vendors, and construction workers are at greater risk due to long hours spent outside.
     

 

Air Pollution in Indian Cities

Several Indian cities are among the most polluted in the world. Cities like Delhi, Kanpur, Patna, and Lucknow often report extremely high levels of PM2.5, especially in winter. During these times, the air quality can be so poor that it is considered "hazardous." This not only affects day-to-day health but also reduces life expectancy over the long term.

 

Steps You Can Take to Protect Yourself

While it may not be possible to eliminate air pollution immediately, there are many things individuals can do to reduce their risk:

1. Check Air Quality Index (AQI)

Use AQI apps or websites to stay informed. Avoid outdoor activities when air quality is very poor.

2. Use Masks

Wearing an N95 or N99 mask helps filter out harmful particles when pollution is high.

3. Stay Indoors

On days with high pollution levels, try to stay indoors, especially during peak traffic hours.

4. Use Air Purifiers

Installing air purifiers at home can help improve indoor air quality, particularly for those with respiratory problems.

5. Improve Ventilation

Ensure good airflow in your home but avoid opening windows during high-pollution periods.

6. Plant Trees

Green spaces help clean the air. If possible, plant trees or keep air-purifying indoor plants like snake plant, aloe vera, or peace lily.

7. Switch to Cleaner Fuels

Using LPG or electricity for cooking instead of wood or coal helps reduce indoor air pollution.

 

What Can Communities and Governments Do?

Large-scale solutions require action from the government and communities:

  • Promoting public transport and reducing the number of private vehicles.
     

  • Controlling industrial emissions and enforcing pollution control norms.
     

  • Creating green zones and increasing tree cover in cities.
     

  • Encouraging use of cleaner fuels and technologies in homes and factories.
     

  • Educating people about the risks of pollution and how to protect themselves.
     

 

Conclusion

Air pollution is a serious threat to respiratory health, especially in a country like India where pollution levels are high in many areas. From asthma to lung cancer, the effects can be severe and long-lasting. However, by staying informed and taking simple precautions, individuals can reduce their risk. It’s also important to support broader actions that aim to reduce pollution at the source.

If you’re concerned about how pollution may be affecting your breathing or health, talk to a healthcare expert. Protect your lungs, stay informed, and take action—because Air Pollution & Respiratory Health should never be ignored.

See all

Live Doctor consultation
Live Doctor Chat

Download Our App & Get Consultation from anywhere.

App Download
call icon for mobile number calling and whatsapp at secondmedic