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Published on: Aug 03, 2021
2 minute read
By: Covid Expert Online

Covid Delta Variant: Virus Is Changing And We Need To Change Too!

Delta Variant: Virus is changing and we need to change too!

The entire world is changing its overall strategy on the coronavirus pandemic this week. Masks are back, vaccine mandates are looming, and officials have sounded more worried than they have in months. Employees must wear a mask throughout the day at work while also keeping distance from others and submitting to a virus test once per week for safety reasons driving these changes as two factors: The large number who remain unvaccinated due to fears about vaccines' health effects combined with Delta variant's rapid spread across Europe over recent weeks which forces authorities around the world into immediate action against disease threat."

The Delta variant, originally known as B.1-617.2 has been around since last year but in recent months it's become the fastest spreading virus of all time according to many experts and scientists who are researching this issue more now than ever before. The US Centers for Disease Control (CDC) have also said that COVID-19 cases have increased over 300% nationally from June 19th to July 23rd along with parallel increases in hospitalizations and deaths are driven by the highly transmissible B: 1 617 2 delta variant which is one of a few reasons why they're so concerned about this new strain because there doesn't seem like any way we can stop or cure it yet if at all.

The Delta variant, originally known as B.1.617.2, has been around since last year but in recent months it's become speedily dominant with an 80% share of newly diagnosed cases across the US according to Centers for Disease Control and Prevention (CDC). The CDC says there have also been "parallel increases" in hospitalizations and deaths which are being driven by this new highly transmissible strain - COVID-19 or what is now better described as the Delta infection

Let's understand what the Delta variant is: a virus that has been around since late last year but in recent months it has become speedily dominant in many countries. It accounts for more than 80% of newly diagnosed cases.

The Delta variant is more transmissible in some studies, but not all. One CDC document indicates the Delta variant to be as contagious as chickenpox with each infected person infecting a few others. This difficult number to check because it requires much testing which has yet been done

The Delta variant is more transmissible than traditional coronavirus, but we don't know by how much. The CDC estimates that the new virus might be about 60-200% as contagious as chickenpox with each infected person infecting eight or nine others on average while a typical case of common cold only has an infection rate of two other people per affected individual. One paragraph from one CDC document indicates that this number could even be higher and since it's difficult to determine exact statistics without comprehensive testing, there are multiple possible outcomes for these estimations.

In a recent presentation, the CDC has noted that vaccines prevent more than 90% of severe diseases but may be less effective at preventing infection or transmission. However, if you're vaccinated with one of two currently approved COVID-19 mRNA vaccine brands (Pfizer and Moderna), then evidence suggests they are highly effective against hospitalization and death for various strains such as Alpha (B.1.1.7) Beta (B 1/351), Gamma( P 1 ), Delta( B/617).

The presentation notes that vaccines are less effective at preventing infection or transmission and sometimes can lead to breakthrough outbreaks in communities despite vaccination. To help combat these effects, the site also noted Moderna's mRNA COVID-19 vaccine is highly effective for many strains of measles including Alpha (B.1.1), Beta (B2) Gamma (P), Delta B(2).

A recent study has shown that the effectiveness of vaccines against certain variants may be lower than previously anticipated. The CDC is urging for ongoing monitoring to ensure appropriate vaccination strategies are developed and implemented with these new findings in mind.

Data suggest that the vaccine is less effective against confirmed infection and symptomatic disease caused by variants of influenza. Ongoing monitoring should be done to ensure that vaccines are still as effective in fighting off Delta variant though lab tests indicate immune response generated should cover it.

Delta has a unique set of mutations that may allow it to evade the human immune system and be more efficient in infecting cells. Delta's changes are limited to its receptor-binding domain, which allows for tight connections with the host cell while also helping this virus escape detection by hiding from our body's natural defenses like antibodies. One change is believed to help make these bonds tighter--making us sicker faster!

The delta virus has at least three mutations on a structure that is called the receptor-binding domain--the part of the disease-causing agent responsible for docking into human cells it infects. It may help evade detection by our immune system, and one mutation, in particular, could make it bind more tightly to infected cells.

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Tuberculosis Symptoms and Treatment: Early Signs, Diagnosis, and Recovery

Tuberculosis (TB) is one of the oldest known infectious diseases and continues to be a major public health concern, especially in developing countries. India accounts for a significant proportion of global TB cases, despite advances in diagnosis and treatment. The good news is that tuberculosis is preventable, treatable and curable when detected early and managed properly.

Understanding tuberculosis symptoms and treatment is critical for reducing disease spread, preventing complications and achieving complete recovery.

What Is Tuberculosis?

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. It primarily affects the lungs (pulmonary TB) but can also involve other parts of the body such as:

lymph nodes
bones and joints
kidneys
brain

TB spreads through the air when an infected person coughs, sneezes or speaks.

Why Tuberculosis Remains a Major Health Issue

According to the World Health Organization and ICMR data:

millions of new TB cases are reported annually
delayed diagnosis increases transmission
incomplete treatment leads to drug resistance

Early detection and treatment are key to TB control.

Common Tuberculosis Symptoms

TB symptoms often develop gradually and may be mild in the early stages, leading to delayed diagnosis.

Persistent Cough

A cough lasting more than two to three weeks is a hallmark symptom of pulmonary TB.

The cough may:

be dry or productive
worsen over time
sometimes produce blood

Fever and Night Sweats

Low-grade fever, especially in the evenings, is common.

Night sweats that soak clothing or bedding are a classic TB sign.

Unexplained Weight Loss

TB increases metabolic demand and reduces appetite, leading to significant weight loss.

Fatigue and Weakness

Persistent tiredness and reduced stamina occur due to chronic infection.

Chest Pain

Chest discomfort or pain may occur during coughing or breathing.

Symptoms of Extra-Pulmonary TB

When TB affects organs outside the lungs, symptoms depend on the site involved and may include:

swollen lymph nodes
bone or joint pain
headaches or neurological symptoms
urinary issues

Why TB Symptoms Are Often Ignored

Many TB symptoms resemble common infections or general weakness.

This leads to:

delayed medical consultation
prolonged transmission
disease progression

Awareness improves early detection.

How Tuberculosis Is Diagnosed

Diagnosis involves a combination of:

sputum tests
chest X-ray
molecular tests such as CBNAAT
blood tests and imaging for extra-pulmonary TB

Early and accurate diagnosis is essential for effective treatment.

Tuberculosis Treatment Explained

TB treatment involves a combination of antibiotics taken over a fixed duration.

Standard TB Treatment

For drug-sensitive TB, treatment typically lasts:

6 months

The regimen includes multiple antibiotics taken in phases to ensure complete bacterial clearance.

Importance of Treatment Adherence

TB bacteria are slow-growing and resilient.

Stopping treatment early can result in:

incomplete cure
relapse
drug-resistant TB

Completing the full course is essential.

Drug-Resistant TB

If TB bacteria become resistant to standard drugs, treatment becomes longer and more complex.

Drug-resistant TB requires:

specialised medications
longer treatment duration
close medical supervision

Prevention of resistance depends on correct treatment from the start.

Side Effects of TB Treatment

Some individuals may experience side effects such as:

nausea
loss of appetite
mild liver enzyme changes

Most side effects are manageable with medical guidance and do not require stopping treatment.

TB and Public Health

TB is not just an individual health issue but a community concern.

Effective TB control requires:

early diagnosis
treatment adherence
contact tracing
public awareness

India’s national TB elimination programmes focus on these strategies.

Preventing Tuberculosis

Preventive measures include:

early detection and treatment of active TB
improving nutrition and immunity
adequate ventilation in living spaces
screening close contacts

BCG vaccination offers partial protection, especially in children.

Living With and Recovering From TB

With proper treatment:

symptoms gradually improve
infection becomes non-contagious
normal life can be resumed

Regular follow-up ensures complete recovery.

When to Seek Medical Help

Consult a healthcare provider if experiencing:

cough lasting more than two weeks
unexplained weight loss
persistent fever or night sweats
blood in sputum

Early action saves lives and prevents spread.

Long-Term Outlook After TB Treatment

Most individuals who complete treatment:

recover fully
regain normal lung function
return to daily activities

Long-term complications are rare with timely care.

Conclusion

Tuberculosis symptoms and treatment must be understood clearly to combat this preventable and curable disease. Persistent cough, fever, night sweats and weight loss should never be ignored. Early diagnosis, complete treatment adherence and regular follow-up are essential for curing TB and preventing transmission. With proper medical care and public awareness, tuberculosis can be effectively controlled and eliminated as a public health threat.

References

Indian Council of Medical Research (ICMR) – Tuberculosis Epidemiology and Treatment Guidelines
World Health Organization (WHO) – Global Tuberculosis Report
National Tuberculosis Elimination Programme (NTEP) – Government of India
Lancet Infectious Diseases – TB Diagnosis and Treatment Outcomes
National Family Health Survey (NFHS-5) – Infectious Disease Indicators
Statista – Global Tuberculosis Burden and Trends

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