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Published on: Jan 02, 2021
2 minute read
By: Dr Rajan Choudhary

COVID-19 Variant: What We Know About This New Mutation

COVID-19 Variant: What we know about this new mutation

In early December a new variant of COVID -19 was detected in the UK, raising concerns across the world. SARS-CoV-2 has already significantly impacted the world, with 84 million cases worldwide and nearly 2 million deaths. Could the new variant cause further havoc? Is it something we should be worried about? Today we will have a look at what we know so far about the virus.

MUTAGENESIS

To start with we should go over viral mutations. Unlike complex organisms, viruses are highly prone to genetic mutations, even more than bacteria. All organisms including humans, birds, even worms, are prone to mutations as well. However due to their complexity, there is much higher risk of mutations causing significant problems with their cellular and genetic processes, problems that are often incompatible with life, or lead to cancer. For this reason, there are significant genetic roadblocks present to prevent such mutations from occurring.

Viruses on the other hand have genetic replication machinery of poor “quality”, prone to introducing mutations. Since they replicate quickly, with little care on which viral particles survive, it matters little if hundreds of viruses do not survive, as further thousands will and continue to spread in their host. It is for this reason we have such difficulty treating viruses or making viruses against them .

COVID VARIANT

The variant was first picked up by the COVID-19 Genomics UK consortium, which undertakes random genetic sequencing of positive COVID-19 samples across the UK. Since April they have sequenced 140,000 virus genomes, to identify and track outbreaks across the UK. The strain was first identified in September and sequenced in early October. However, the significance of this strain was not realized until the end of the year. By 13th December 1108 cases had been identified across 60 different locations, though the true number is likely much higher. In Norfolk, it accounts for nearly 20% of all samples.

17 Variations have been identified, most significantly in the spike protein the virus uses to bind to the ACE2 receptor found in the lungs. Changes in this protein may have resulted in it being more infectious and spreading more quickly between people. A review of current evidence has shown the rate of transmission was 71% higher than the other variants and may also have a much higher viral load. This has given it an advantage over the other COVID-19 strains- it has already been detected in South Africa, Europe, and America, and it is likely to become the dominant global strain in the near future.

It appears children are more susceptible to catching this virus. The virus propagated at a time when schools were open and running, whilst the rest of the country remained in lockdown. This may have provided a larger pool of children for the virus to spread in, resulting in this change. However, this does not mean that the virus “attacks” children, rather it is able to attach to ACE2 receptors in children’s lungs with greater ease and spread quickly.

VACCINE

The most important question on everyone’s mind – will the vaccine be effective against this new strain? If not, lockdown rules may be extended until new vaccines are discovered, and by then newer strains may leapfrog ahead and make the new vaccines irrelevant again.

So far experts believe that the new variant is unlikely to make vaccines ineffective. The vaccines all produce antibodies against the viral spike protein, but so far it appears the mutation has not changed the shape or function of the spike protein enough for antibodies to fail against it. The antibodies should be able to recognize enough sites on the spike protein to successfully attach, neuter the protein, and present the virus for destruction by the body’s immune system. Unfortunately, it will take some time to fully understand the effects of the mutation, though we can remain hopeful for now

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Clothing Drives for Secondhand Donation: Serving Society Sustainably

Clothing is a basic human need, yet millions of people across India lack access to adequate apparel, especially during extreme weather conditions. At the same time, urban households discard large volumes of wearable clothing each year. Clothing drives for secondhand donation bridge this gap by connecting surplus with need in a dignified, sustainable manner.

These initiatives are not merely charitable activities. They represent a structured approach to social responsibility, environmental stewardship and community wellbeing.

The Growing Need for Clothing Donation in India

India faces significant socio-economic disparity.

According to government and NGO data:

millions live below the poverty line
seasonal weather exposes vulnerable populations to health risks
access to basic clothing remains inconsistent

Clothing insecurity directly affects dignity, health and social participation.

Environmental Impact of Textile Waste

The fashion and textile industry is among the largest contributors to environmental pollution.

Textile waste leads to:

landfill accumulation
water pollution from dyes
increased carbon footprint

Reusing clothing through donation significantly reduces environmental strain.

Why Secondhand Clothing Matters

Secondhand clothing extends the lifecycle of garments.

Benefits include:

reduced demand for new production
conservation of water and energy
lower environmental emissions

According to sustainability studies, reuse has a far lower environmental cost than recycling or disposal.

Social Impact of Clothing Drives

Clothing donation drives provide:

protection from heat, cold and rain
improved hygiene and comfort
enhanced dignity and self-esteem

For recipients, clean, appropriate clothing supports physical health and social inclusion.

Role of Clothing Drives in Community Wellbeing

Community-based donation drives:

encourage collective responsibility
foster empathy and awareness
strengthen social bonds

When organised locally, they ensure relevance and timely distribution.

Corporate and Institutional Participation

Many organisations integrate clothing drives into CSR initiatives.

Benefits for organisations include:

measurable social impact
employee engagement
alignment with sustainability goals

EY-FICCI CSR reports highlight employee-driven social initiatives as highly effective engagement tools.

How to Organise an Effective Clothing Drive

Successful drives follow structured processes.

Key steps include:

clear communication on donation guidelines
segregation by size, gender and season
quality checks for usability
hygienic packing and storage

Organisation ensures dignity for recipients.

Importance of Quality and Dignity

Donations should always respect the recipient.

Essential guidelines:

clothes must be clean and wearable
damaged or unusable items should be excluded
culturally appropriate clothing should be prioritised

Dignified donation builds trust and respect.

Seasonal Relevance of Clothing Drives

Seasonal drives maximise impact.

Examples include:

winter clothing drives
monsoon protection apparel
school clothing collections

Timing ensures practical usefulness.

Health and Wellbeing Benefits

Adequate clothing reduces:

exposure-related illnesses
skin infections
respiratory conditions during cold weather

WHO recognises appropriate clothing as a basic determinant of health.

Sustainability and Circular Economy

Clothing drives support a circular economy by:

keeping materials in use longer
reducing waste generation
encouraging responsible consumption

They align with global sustainability goals.

Community Partnerships and NGOs

Collaborating with NGOs ensures:

efficient distribution
identification of genuine needs
transparency and accountability

Partnerships amplify reach and impact.

Measuring the Impact of Clothing Drives

Impact can be assessed through:

number of beneficiaries
quantity of clothing reused
environmental waste reduction
community feedback

Data-driven evaluation improves future initiatives.

Challenges and How to Address Them

Common challenges include:

poor-quality donations
storage and logistics issues
uneven distribution

Clear guidelines and partnerships help overcome these barriers.

Long-Term Value of Sustainable Donation Drives

Regular clothing drives:

normalise responsible disposal habits
build sustainable communities
encourage conscious consumption

They move society from waste to welfare.

Integrating Clothing Drives with Broader Wellness Initiatives

Clothing drives complement:

health camps
nutrition programs
community wellness initiatives

Holistic approaches improve overall social wellbeing.

Conclusion

Clothing drives for secondhand donation represent a powerful intersection of compassion and sustainability. By redirecting wearable clothing to those who need it most, these initiatives protect dignity, improve health outcomes and reduce environmental impact. In a society striving for sustainable development, organised clothing donation drives serve as practical, high-impact actions that benefit communities and the planet alike. When individuals and organisations come together to serve responsibly, small acts of reuse create lasting social change.

References

World Health Organization (WHO) – Social Determinants of Health Reports
Indian Council of Medical Research (ICMR) – Environmental and Community Health Studies
NITI Aayog – Sustainability and Social Impact Frameworks
EY-FICCI – Corporate Social Responsibility and Sustainability Reports
Statista – Textile Waste and Sustainability Data
UN Environment Programme – Sustainable Consumption and Circular Economy

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