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Published on: Apr 04, 2020
2 minute read
By: Dr Rajan Choudhary

COVID-19 LOCKDOWN !

As the cases continue to increase worldwide more and more countries have begun to take drastic measures to prevent the spread of COVID-19. In some places it is clear containment is no longer achievable, as too many people have become infected and the natural exponential increase in number of cases is inevitable. Now the focus switches to damage mitigation.

We first saw this in Wuhan, with city wide quarantine measures. Then Italy enacted similar measures, now extending across the country with all non-essential services and businesses closed for the foreseeable future. The Italian health service has become strained with the rising patient load, with reports of drastic measures taken in hospitals including conversion of operating theatres into intensive care bays. We have previously discussed the effect this has had on the Italian economy.

A NEW EPICENTRE

With Europe now seen as the “epicentre” of the pandemic, other countries have begun following suit. Spain is the second hardest hit country in Europe, with 6,000 infections and nearly 200 deaths. After a lengthy meeting of the government cabinet, the Spanish PM has enacted a partial lockdown of the country, with the use of armed forces on standby to assist. This includes closure of all shops except those selling food and basic necessities, reduction in medium-distance rail traffic to stem the spread of people around the country, and economic measures to support business workers.

France has also shut down all non-essential businesses, with food shops, chemists, banks and petrol stations remaining unaffected. The PM urged a reduction in travel amongst the population, and to enact “social distancing”. Germany has 3,800 cases but remarkably has only had 8 deaths so far. Berlin has banned all public and private events with more than 50 participants, with similar bans occurring in other cities across the countries.

So what do they hope to achieve with such measures? At first people were advised to take measures to wash hands, practice basic hygiene, self-quarantine if developing symptoms. But it became apparent this was not enough. Social distancing and lockdowns further reduce the spread of the virus by drastically reducing the number of people out in public, the number of interactions they can have. Schools and universities act as breeding grounds for infections, large congregations amongst which respiratory infections can spread like wildfire.

SHUT DOWN EVERYTHING

Lockdown also carries great political power. People respond well to drastic action, rather than soft recommendations to slightly change their daily habit with washing hands and increased hygiene. This is why masks have been so popular amongst the populous. It is decisive, it is visible. It is however NOT recommended by the WHO and most governments to wear as it is unnecessary unless around infected patients, and increased demands is straining supply for medical professionals and those who truly need it.

Similarly, Lockdown is a decisive action. It reassures the population that something is being done, that the government is taking the IT seriously. But it is not a cure to COVID. It is a plaster, a temporary stopping measure, one that cannot continue indefinitely. Shutting businesses can seriously affect the economy, affect people’s income and subsequently prevent them from paying off mortgages or loans. Forcing children to stay at home can affect their education, parents have to choose whether to work or look after their unsupervised kids.

It’s true that lockdown is now a necessity in some countries, and the lockdown of the Hubei province and parts of China was credited with significantly slowing down the spread of COVID. But it will not stop the viral spread completely. For this reason the UK has adopted an alternate strategy, one that we will discuss in our next blog.

Dr Rajan Choudhary, London UK

Head Of Products, Second Medic Inc

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Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

Gene mutations
Family-linked disease patterns
Hereditary cancer markers
Metabolic and cardiovascular risks
Neurological conditions
Autoimmune predispositions

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

Breast
Ovarian
Colorectal
Prostate
Pancreatic

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

Cholesterol levels
Plaque formation
Blood pressure regulation

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

People with family history of cancer
Individuals whose relatives had early heart attacks
Families with diabetes across generations
Women with breast or ovarian cancer history
Couples planning pregnancy
People with unexplained chronic conditions
Individuals wanting personalized preventive healthcare

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

AI-based genome interpretation
Affordable whole-genome sequencing
Predictive analytics for early cancer
Family-wide health risk mapping
Integration with digital health IDs under ABDM

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

ICMR – Genetic research insights
NIH – Genetic testing guidelines
WHO – Genomic medicine developments
Statista – DNA testing market India
SecondMedic genetic health studies

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