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Published on: Jul 07, 2020
1 minute read
By: Dr Rajan Choudhary

Asymptomatic Carriers Of COVID

Why Asymptomatic carriers of COVID are as dangerous as symptomatic patients

Many countries have now begun enforcing masks for everyone to wear when out in public, in enclosed spaces, or on public transport. There is good evidence to support these measures, but unfortunately, some still show resistance to the idea. Whilst some reasons put forward are non-sensical (masks do not cause any noticeable or measurable decrease in oxygen delivery to the body), other people feel like they shouldn’t wear a mask because they do not have symptoms of COVID. And thus would not spread anything. Here we look at a recent publication in Nature, one of the most esteemed peer-reviewed scientific journals in the world, and what it shows us about the transmission of COVID in a population.

This study by Lavezzo et al looked at the suppression of the SARS-CoV-2 outbreak in the Italian municipality of Vo’. This municipality is 50 kilometers west of Venice with a population of just 3,416 people. It experienced its first casualty of COVID on the 21st of February, after which it underwent lockdown for 14 days. During this time data was collected on the clinical presentation and hospitalization of COVID patients, as well as other citizens through the contact tracing network.

In total 2,812 residents were tested in late February, with another 2,343 tests performed two weeks later at the end of lockdown. Nasal and throat swabs were taken to identify infected individuals. The study found only 2.6% of people were positive for COVID at the start of lockdown, which reduced to 1.2% two weeks later.

Out of this infected population, 42.5% were asymptomatic. They had no symptoms at the time of swab testing nor did they develop symptoms afterwards. When the viral load was measured between symptomatic and asymptomatic patients, there was little difference.

Evidence has pointed to a large asymptomatic population, and previous studies have shown it to be as high as 50% in some cases. Many would assume if a patient has no symptoms then they must have fought the infection before it became an issue, or had a very low viral load and therefore were not likely to spread it. This study shows it is simply not true. Asymptomatic carriers of COVID are likely to contribute to the transmission and spread of COVID amongst the population.

If you are asymptomatic you have as high a viral load as someone who is symptomatic. But there is no way to tell without a swab. You have as much of a potential to spread the infection to the vulnerable. Even in people who became symptomatic the height of transmission was found to be before the patient showed any symptoms.

So what does this mean? If you have COVID you are likely to spread it before you show any symptoms or any symptoms at all. We know masks are effective at significantly reducing the spread of COVID, by catching the water droplets that carry the SARS-CoV-2 Virus. Now that shops and public places are re-opening, the risk of spread is high.

Wear a mask. Stop the spread.

https://www.nature.com/articles/s41586-020-2488-1_reference.pdf suppression of a SARS article

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Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

Gene mutations
Family-linked disease patterns
Hereditary cancer markers
Metabolic and cardiovascular risks
Neurological conditions
Autoimmune predispositions

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

Breast
Ovarian
Colorectal
Prostate
Pancreatic

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

Cholesterol levels
Plaque formation
Blood pressure regulation

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

People with family history of cancer
Individuals whose relatives had early heart attacks
Families with diabetes across generations
Women with breast or ovarian cancer history
Couples planning pregnancy
People with unexplained chronic conditions
Individuals wanting personalized preventive healthcare

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

AI-based genome interpretation
Affordable whole-genome sequencing
Predictive analytics for early cancer
Family-wide health risk mapping
Integration with digital health IDs under ABDM

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

ICMR – Genetic research insights
NIH – Genetic testing guidelines
WHO – Genomic medicine developments
Statista – DNA testing market India
SecondMedic genetic health studies

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