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Published on: Apr 04, 2020
3 minute read
By: Dr Rajan Choudhary

Declaring A Pandemic — What Does This Mean ?

Its finally happened. Three months after the first case was reported in Wuhan, China, and after a 13 fold increase in cases in just two weeks, the World Health Organisation has designated COVID-19 a pandemic. This disease has resulted in over 121,500 confirmed cases across 114 nations, and 4,300 deaths, over 3,000 of them in China alone.

The WHO has shown alarm at some countries that have shown “alarming levels of inaction” and hope the new designation of pandemic will shock these nations into action. “This is not just a public health crisis, it is a crisis that will touch every sector,” said Dr. Tedros Adhanom Ghebreyesus, WHO director-general, at a media briefing. “So every sector and every individual must be involved in the fights.”

Despite this new update, it is not too late for nations to act, and countries can still impact the course of the outbreak by detecting, testing, treating and isolating patient, with further education to the public and contact tracing of cases.

WHAT IS A PANDEMIC

An epidemic is an increase in the spread of a disease within a community, and can be relatively common. Sometimes a single disease may spread rapidly in a small, unprepared community creating an epidemic. This is happening more often with the prevalence of the anti-vaxx movement, as immunity falters against preventable diseases like measles.

A pandemic on the other hand is the global outbreak of a serious new illness that is “sustainably transmitted throughout the world”. It is not a descriptor that is used lightly, as declaring a pandemic could “cause unreasonable fear, or unjustified acceptance that the fight is over,” if used incorrectly. There has been much discussion whether the declaration of N1N1 “swine flu” as a pandemic caused unnecessary panic, overwhelmed emergency services or caused excessive expenditure on antiviral medication.

Though they were concerned by the spread of the disease and came close by labelling it a “pandemic potential”, the WHO were reluctant to declare it one. Unfortunately, after 2 months of assessing the outbreak, members of the WHO were concerned “both by the alarming levels of spread and severity, and by the alarming levels of inaction.” There is no threshold, number of deaths, number of countries affected.

WHAT DOES THIS MEAN FOR THE COUNTRIES?

According to the World Bank, the annual global cost of a severe pandemic is around $570 billion, or 0.7% of the entire world’s income. This estimation is realised as more people stay at home and more authoritative measures are enforced by governments. At this time, Italy has not put in place nationwide quarantine with further closure of almost all shops and services bar food shops and chemists.

The UK is expected to move from the “containment” phase of the outbreak, aimed at halting the spread of the disease”, to “delay”. This instead accepts the disease cannot be contained, and instead looks to slow its progression. Measures such as “social distancing”, isolation of those showing minor viral symptoms and cancellation of social events. To prepare for the UK epidemic a £30bn package has been prepared to boost the economy during the COVID outbreak.

India has suspended all tourist visas and e-visas until April 15ht as a pandemic is declared. All incoming travellers including Indian nationals will be quarantined for a minimum of 14 days if they have visited China, Italy, Iran, Korea, France, Spain and Germany after 15ht February. Advice has also been given to avoid all non-essential travel abroad.

South Korea has ramped up testing, performing around 4,000 tests per million people between 3rd January and 11th March. In comparison to 1,000 per million in Italy, 400 per million in the UK and only 28 in the UK. This has been due to differences in government responses, the severity of outbreaks in each country and the nature of the healthcare system in each country.

The steady decrease in new coronavirus cases in South Korea has been attributed to this mass testing, improved public communications and the use of new technology to aid diagnosis and management. Interestingly it has been achieved without the drastic quarantine procedures in place in China and Italy.

WHAT SHOULD I DO

Washing your hands has been emphasised by almost all public health agencies and governments. And you should continue to follow this advice. Soap and water is one of the most effective ways to destroy the virus on your hands, and helps prevent its spread.

It is also important to avoid panic, and to not hoard soap, food and toilet roll. Do not trust forwards on WhatsApp or treatment advice suggested, as these can be ineffective or even dangerous. Recently 27 people died from alcohol poisoning after a myth was spread stating strong alcohol could cure coronavirus.

Similarly be wary of false cures being sold online or by un reputable stores. Currently there is no cure for COVID, and supportive treatment is required for those who fall extremely ill.

If you have symptoms of COVID-19, you should self-isolate and notify your local health authorities. Symptoms include fever, cough, sneezing, general lethargy and joint pain, symptoms similar to the flu.

If you have confirmed COVID and have been asked to quarantine yourself, PLEASE STAY INDOORS. There have been instances of infected people continuing to partake in everyday activities, resulting in the spread of the infection, sometimes to vulnerable children and the elderly.

Dr Rajan Choudhary, Product Head, Second Medic Inc, UK

www.secondmedic.com

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Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

Gene mutations
Family-linked disease patterns
Hereditary cancer markers
Metabolic and cardiovascular risks
Neurological conditions
Autoimmune predispositions

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

Breast
Ovarian
Colorectal
Prostate
Pancreatic

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

Cholesterol levels
Plaque formation
Blood pressure regulation

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

People with family history of cancer
Individuals whose relatives had early heart attacks
Families with diabetes across generations
Women with breast or ovarian cancer history
Couples planning pregnancy
People with unexplained chronic conditions
Individuals wanting personalized preventive healthcare

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

AI-based genome interpretation
Affordable whole-genome sequencing
Predictive analytics for early cancer
Family-wide health risk mapping
Integration with digital health IDs under ABDM

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

ICMR – Genetic research insights
NIH – Genetic testing guidelines
WHO – Genomic medicine developments
Statista – DNA testing market India
SecondMedic genetic health studies

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