• Published on: Jul 24, 2024
  • 3 minute read
  • By: SecondMedic Expert

Why Dengue Fever Causes Low Platelet Counts And How To Manage It

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Dengue fever, a mosquito-borne viral infection, has become a significant public health concern in many tropical and subtropical regions. One of the hallmarks of severe dengue is a drop in platelet count, which can lead to serious complications. Understanding why dengue fever causes low platelet counts and how to manage this condition is crucial for anyone living in or traveling to affected areas.

Understanding Dengue Fever

Dengue fever is caused by the dengue virus, which is transmitted primarily by Aedes aegypti mosquitoes. The virus has four distinct serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). Infection with one serotype usually provides lifelong immunity against that specific type, but only partial and temporary immunity against the others. Subsequent infections with a different serotype increase the risk of severe dengue, including dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).

Why Dengue Fever Causes Low Platelet Counts

Platelets are small blood cells that play a crucial role in blood clotting. A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Dengue fever often leads to a significant drop in platelet count, a condition known as thrombocytopenia. There are several reasons for this:

1. Bone Marrow Suppression: The dengue virus can infect and impair the bone marrow, which is responsible for producing blood cells, including platelets. This leads to reduced platelet production.

2. Increased Platelet Destruction: The virus and the immune response it triggers can increase the destruction of platelets. The body’s immune system mistakenly targets platelets, thinking they are infected cells.

3. Increased Utilization: In severe dengue, there is increased leakage of plasma from the blood vessels. To combat this, the body uses up more platelets for clotting, leading to lower counts in the bloodstream.

4. Splenic Sequestration: The spleen may sequester or hold onto more platelets than usual in dengue fever, reducing the number of platelets circulating in the blood.

Symptoms of Low Platelet Count

A low platelet count can lead to several symptoms, which may vary in severity:

- Easy bruising

- Petechiae (small red or purple spots on the skin)

- Bleeding gums or nosebleeds

- Blood in urine or stools

- Heavy menstrual bleeding

- Fatigue and weakness

In severe cases, internal bleeding and shock can occur, which are life-threatening conditions requiring immediate medical attention.

How to Manage Low Platelet Counts in Dengue Fever

Managing low platelet counts in dengue fever involves several strategies aimed at supporting the patient until their body recovers. Here are some key approaches:

1. Hydration

Maintaining adequate hydration is crucial. Fluids help maintain blood volume and support overall bodily functions. Oral rehydration solutions, coconut water, and plain water are often recommended. In severe cases, intravenous (IV) fluids may be necessary.

2. Monitoring Platelet Counts

Regular monitoring of platelet counts is essential to assess the severity of thrombocytopenia. This helps healthcare providers decide on the necessary interventions and monitor recovery.

3. Medications

There are no specific antiviral medications for dengue. However, supportive care includes:

Acetaminophen: To reduce fever and relieve pain. Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin, as they can increase the risk of bleeding.

Platelet Transfusions: In cases of very low platelet counts or significant bleeding, platelet transfusions may be necessary.

4. Rest and Nutrition

Adequate rest and proper nutrition support the body's recovery. A balanced diet rich in fruits, vegetables, and lean proteins can help maintain energy levels and support immune function.

5. Avoiding Certain Foods and Activities

Patients with low platelet counts should avoid activities that can increase the risk of bleeding, such as contact sports. Additionally, foods that may thin the blood, like garlic and ginger, should be consumed in moderation.

6. Natural Remedies

Some natural remedies are believed to help increase platelet counts, although scientific evidence is limited. These include:

Papaya Leaf Extract: Some studies suggest that papaya leaf extract can help increase platelet counts.

Pomegranate and Kiwi: These fruits are rich in vitamins and antioxidants that support overall health.

Preventing Dengue Fever

Preventing dengue fever is the best way to avoid complications like low platelet counts. Preventive measures include:

Mosquito Control: Eliminate standing water around your home, use mosquito repellents, and install screens on windows and doors.

Protective Clothing: Wear long-sleeved shirts, long pants, socks, and shoes when outdoors.

Vaccination: In some regions, a dengue vaccine is available and recommended for individuals who have had a previous dengue infection.

Conclusion

Dengue fever and its complications, such as low platelet counts, pose significant health challenges in many parts of the world. Understanding the reasons behind thrombocytopenia and implementing effective management strategies can help mitigate the risks and support recovery. By taking preventive measures and staying informed, individuals can reduce their risk of dengue fever and its potentially severe consequences.

Read FAQs


A. Dengue fever causes low platelet counts due to bone marrow suppression, increased platelet destruction, increased utilization for clotting, and splenic sequestration. The dengue virus affects the body's ability to produce and maintain adequate platelet levels.

A. Managing low platelet counts involves staying hydrated, monitoring platelet levels, taking acetaminophen for fever and pain, resting, eating a nutritious diet, and avoiding activities and foods that increase bleeding risk. In severe cases, platelet transfusions may be necessary.

A. Signs of a low platelet count include easy bruising, petechiae (small red or purple spots on the skin), bleeding gums or nosebleeds, blood in urine or stools, heavy menstrual bleeding, fatigue, and weakness. In severe cases, internal bleeding and shock may occur.

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Human Metapneumovirus (HMPV)

Human Metapneumovirus (HMPV): Treatment & Symptoms

Human Metapneumovirus (HMPV) is a respiratory virus that causes illness in people of all ages, particularly young children, older adults, and people with weakened immune systems. The virus can lead to conditions such as bronchitis, pneumonia, and upper respiratory infections. With rising cases globally and in India, awareness about HMPV, its symptoms, and available treatment options is essential.

In this blog, we'll break down everything you need to know about Human Metapneumovirus (HMPV): Treatment & Symptoms in easy-to-understand language.

 

What is Human Metapneumovirus (HMPV)?

HMPV is a virus that belongs to the Paramyxoviridae family—the same group of viruses responsible for illnesses like RSV (Respiratory Syncytial Virus) and mumps. It was first discovered in 2001 but is now known to have been circulating for decades.

The virus mainly affects the respiratory tract and can range from mild cold-like symptoms to severe lower respiratory infections. It spreads most commonly in late winter and spring, similar to flu season.

 

HMPV in India: Current Overview

In 2025, several hospitals in India have seen a rise in cases of HMPV among children and elderly patients. Though not as widely known as COVID-19 or flu, Human Metapneumovirus is a common cause of pediatric hospital admissions during respiratory infection surges.

Doctors advise taking it seriously because it can mimic flu or pneumonia, making early diagnosis crucial.

 

Common Symptoms of HMPV

The symptoms of HMPV are similar to other respiratory viruses. They can range from mild cold-like symptoms to severe breathing difficulties, especially in vulnerable groups.

Main Symptoms Include:

  • Fever

  • Cough

  • Runny nose

  • Nasal congestion

  • Sore throat

  • Wheezing

  • Shortness of breath

  • Fatigue

  • Loss of appetite (especially in children)
     

In severe cases, it can lead to bronchitis or pneumonia.

 

How is HMPV Transmitted?

Human Metapneumovirus spreads from person to person through:

  • Coughing and sneezing

  • Close personal contact

  • Touching contaminated surfaces or hands
     

The virus can survive on surfaces like toys, doorknobs, and tables for several hours. That’s why regular handwashing and hygiene are essential.

 

How is HMPV Diagnosed?

Since HMPV symptoms resemble other viral infections, a lab test is the only way to confirm the virus.

Tests may include:

  • RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) for detecting viral RNA

  • Nasopharyngeal swabs

  • Rapid antigen tests (less common)
     

In India, you can book respiratory virus panels or flu-like illness tests from diagnostic labs like Thyrocare through SecondMedic to check for multiple viruses including HMPV.

 

Human Metapneumovirus (HMPV): Treatment

There is no specific antiviral drug for HMPV. Treatment is mainly supportive, aimed at relieving symptoms.

Supportive Treatments:

  • Fever reducers like paracetamol

  • Cough suppressants

  • Steam inhalation

  • Hydration (drinking fluids)

  • Rest
     

Hospitalization is required if:

  • Breathing becomes difficult

  • Oxygen levels drop

  • Patient is elderly, a young child, or has chronic illnesses (like asthma or heart disease)
     

Doctors may provide oxygen therapy or nebulizers to ease breathing in severe cases.

 

How to Prevent HMPV

As with many respiratory infections, prevention is the best protection.

Tips to Avoid Infection:

  • Wash your hands regularly with soap and water.

  • Use alcohol-based hand sanitizers when outside.

  • Cover mouth and nose when sneezing or coughing.

  • Avoid touching your face, especially eyes and nose.

  • Disinfect commonly used surfaces at home and work.

  • Avoid close contact with sick individuals.

  • Wear a mask in crowded places during flu season.
     

There is no vaccine for HMPV yet, but researchers are working on developing one.

 

Who is Most at Risk?

  • Infants and toddlers (under 5 years)

  • Adults over 65

  • People with weakened immune systems

  • Individuals with chronic respiratory or heart diseases
     

These groups may experience more severe symptoms and need urgent care if infected.

 

When to See a Doctor

You should consult a doctor if:

  • Symptoms last more than 5–7 days

  • Breathing becomes difficult

  • Fever is very high or persistent

  • There's chest pain or confusion

  • A child has a bluish face or lips
     

Early intervention can prevent complications.

 

Recommended Tests on SecondMedic (Powered by Thyrocare)

While there is no HMPV-specific test for home collection, you can book tests like:

  1. Complete Blood Count (CBC)

  2. CRP (C-Reactive Protein)

  3. Respiratory Pathogen Panel

  4. Influenza A & B Detection

  5. RT-PCR Viral Panels (on request)
     

Visit SecondMedic’s Lab Test Section to explore packages and book your test online.

 

Conclusion

Human Metapneumovirus (HMPV) is a growing cause of respiratory illness in India, especially in children and the elderly. Though there is no specific cure, early diagnosis and symptom-based treatment can help patients recover fully. Practicing good hygiene and avoiding close contact with sick people are the best ways to prevent infection.

Stay informed and protect your loved ones. For detailed insights and medical advice, bookmark this guide on "Human Metapneumovirus (HMPV): Treatment & Symptoms."

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