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Published on: Apr 13, 2020
3 minute read
By: Dr Rajan Choudhary

Plasma Treatment For COVID-19?

TREATING COVID WITH BLOOD

We have previously covered proposed treatments for COVID-19, in particular hydroxychloroquine, and explained why we shouldn’t look for a magic cure for this disease. Viruses are difficult to treat, and ultimately supportive treatment appears to be best we can achieve. But an editorial published in BioMedicine Central appears to show a novel treatment for the most ill patients, one that may have flown under most people’s radar.

“A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19”

An interesting title. Lets dissect it.

SUMMARY

- Blood is made up of many different components

- The immune system recognises the virus and produces antibodies against it to neutralise it

- These antibodies float in the blood plasma, a watery solution

- The plasma can be extracted from donated blood, and given to patients suffering from COVID-19

- So far evidence suggests it can help treat the most seriously affected patients.

WHAT IS IN OUR BLOOD

To understand this we must first understand what our blood is made of. Most people know that blood functions to transport oxygen from our lungs. But this is an oversimplification. Blood has many different functions:

- Transport: along with oxygen it transports sugars, fats, protein subunits throughout the body. This is done with the watery PLASMA of the blood.

- Clot: cells and protein structures act to plug any holes that form from cuts and damage. This is done by the PLATELETS in the blood

- Immunity: Immune cells respond to bacteria, viruses, parasites in the blood and body. They target these pathogens, identify and tag them with antibodies, and ultimately destroy them. This is done by the WHITE BLOOD CELLS.

And many more functions that we won’t bore you with.

IMMUNITY

It is this last point that is of interest to us. Our immune system consists of white blood cells that can recognise invading organisms in the blood, around cells and even invaders hiding within our own cells. All cells have protein markers on their surface, no matter if its human cells, bacterial, viral, fungal etc. These markers can be highlighted and targeted by specialised white blood cells, who in turn produce antibodies against these markers. Think of antibodies as handcuffs with flares attached: once attached other white blood cells use this information to find and destroy the invaders.

What is amazing about antibodies is how complex they are. The proteins in our body are incredibly complex. They are long chains that fold into unique shapes depending on hundreds of different types of chemical interactions. These are so complex that supercomputers can take literal years to figure out the shape of a single protein and how it folds depending on the subunits in its chain. This means that our immune system has to recognise these markers and figure out a complementary tag out of hundreds of billions of potential sequences. Antibodies have to be specific to their tag. If an antibody is produced that can target more than one tag, it can cause problems. If it targets a bacterial tag, but accidentally highlights the person’s cells as well, the immune system will start targeting and destroying the person’s organs. These auto-immune disorders can be devastating.

But when they work, antibodies are miraculous. They persist in the blood after an infection, and if a second infection occurs, memory cells in the blood can rapidly produce these antibodies before the infection can even produce symptoms. This is known as immunity, and is why we usually don’t get the same illness twice. Antibody based treatment is see as the future of medical therapy, and is something we will cover in future blogs.

PLASMA EXCHANGE

From population testing we can see that the majority of patients with COVID-19 recover, experiencing either mild symptoms, moderate symptoms requiring some form of treatment and hospitalisation, or no symptoms whatsoever. In these patients their immune system will have successfully recognised the virus and produced antibodies against it to neutralise the virus. It is the patients with severe symptoms, those in which the virus is running rampant in the body, that the production of antibodies happens too late.

Plasma exchange involves obtaining blood from patients who have beaten the virus, spinning the blood to separate out the red cells, white cells, platelets and watery plasma. The plasma contains all the glucose, small proteins and importantly for us, the antibodies. This plasma can be transfused into patients with COVID-19 that cannot cope, in order to help their immune system. These transfused antibodies will neutralise some of the viruses in the patient, reducing the viral load, amount of replication and cell destruction that causes such devastating symptoms in COVID-19.

The published editorial showed that in the most critical pneumonia patients, requiring mechanical ventilators and drugs to support the heart, mortality in plasma exchange patients resulted in a 47.8% mortality instead of 81.3%. Of course it is a single study with a limited number of patients, but the results are encouraging. It is further helped by the fact plasma exchange is a well established therapy, with established protocols known to intensivists and haematologists.

THE FUTURE

We may see the use of Plasma exchange for critically ill patients increase as the pandemic continues. It is not a treatment option available for everyone, as it requires intravenous access and careful monitoring in a controlled setting. But it also needs donation from people who have recovered from COVID and have suitable antibodies. So whilst it might not be a magic pill that everyone expects to cure COVID, it might be the difference between life and death for those that need it most.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

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Secondmedic Lunch & Learns: How Combining Skill Building and Health Education Transforms Workplace Wellness

Corporate wellness is no longer limited to annual health checkups or fitness challenges. Modern organisations recognise that sustained employee wellbeing requires continuous learning, awareness and engagement. Secondmedic Lunch & Learns are designed around this philosophy, bringing together skill development and health education in a format that is practical, engaging and easy to implement.

By using informal lunchtime sessions, organisations create a safe, relaxed environment where employees can learn, ask questions and apply knowledge immediately.

What Are Lunch & Learn Sessions?

Lunch & Learn sessions are short, focused learning programs conducted during lunch hours.

They:

minimise disruption to work
encourage voluntary participation
promote informal learning

Secondmedic enhances this format by integrating health education with essential workplace skills.

Why Combine Skill Development with Health Education?

Health and performance are deeply interconnected.

Employees who understand:

stress management
nutrition
ergonomics
mental wellbeing

are better equipped to:

focus
collaborate
perform consistently

NITI Aayog workforce reports highlight that health literacy directly influences productivity and engagement.

The Growing Need for Workplace Health Education in India

India faces a rising burden of lifestyle diseases.

According to ICMR and NFHS-5:

a large portion of the working population has undiagnosed risk factors
stress and sedentary behaviour are increasing
health awareness remains low despite access to information

Workplaces offer the ideal platform for preventive health education.

How Secondmedic Lunch & Learns Are Structured

Secondmedic Lunch & Learns follow a structured yet flexible format:

short expert-led presentations
interactive discussions
real-life case examples
practical takeaways

Sessions are designed to be concise, engaging and actionable.

Health Topics Commonly Covered

Health education topics include:

preventive health and early detection
stress and mental wellbeing
nutrition for working professionals
sleep health and fatigue management
posture and ergonomic safety

These topics address everyday challenges faced by employees.

Skill-Focused Learning Areas

Alongside health, sessions also support professional growth through:

communication skills
time and energy management
resilience and adaptability
decision-making under pressure

This dual focus enhances overall workplace capability.

Benefits for Employees

Improved Health Awareness

Employees learn how daily habits affect long-term health.

Practical Skill Application

Skills taught can be used immediately at work and home.

Higher Engagement

Interactive sessions increase participation and interest.

Reduced Stress

Knowledge empowers employees to manage stress better.

Benefits for Employers

Stronger Wellness Culture

Learning-driven wellness signals genuine organisational care.

Better Productivity

Healthy, skilled employees perform more consistently.

Reduced Absenteeism

Preventive education lowers illness-related leave.

High ROI Initiative

Lunch & Learns are cost-effective and scalable.

EY-FICCI reports show that preventive wellness programs deliver long-term savings for organisations.

Why Lunch Hours Work Best

Lunchtime sessions:

feel informal and relaxed
encourage open participation
avoid meeting fatigue

Employees are more receptive when learning is integrated naturally into the day.

Virtual and Hybrid Lunch & Learns

Secondmedic adapts sessions for:

in-office teams
remote employees
hybrid workplaces

This ensures consistent learning experiences across locations.

Role of Medical and Subject Experts

Sessions are led by:

doctors
nutritionists
mental health professionals
trained facilitators

Expert-led content ensures accuracy and trust.

Encouraging Behaviour Change Through Education

Information alone does not drive change.

Secondmedic focuses on:

practical examples
small habit shifts
realistic goal setting

Lancet behaviour change studies confirm that interactive education improves long-term adherence.

Measuring Impact of Lunch & Learns

Organisations often observe:

higher session attendance
improved employee feedback
increased health screening participation
better engagement scores

These metrics demonstrate sustained value.

Aligning Lunch & Learns with Preventive Healthcare

Lunch & Learns complement:

preventive health checkups
wellness campaigns
digital health initiatives

They reinforce messages and encourage proactive health decisions.

Customisation for Organisational Needs

Secondmedic customises sessions based on:

workforce demographics
industry-specific risks
organisational goals

Tailored content improves relevance and impact.

Long-Term Value of Continuous Learning

Wellness is not a one-time intervention.

Regular Lunch & Learns:

reinforce healthy behaviours
build long-term awareness
create a learning culture

WHO emphasises continuous education as a pillar of workplace health promotion.

Conclusion

Secondmedic Lunch & Learns represent a modern, effective approach to corporate wellness by combining skill development with health education. These sessions empower employees with knowledge that improves both personal wellbeing and professional performance. Easy to implement, cost-effective and highly engaging, Lunch & Learns help organisations build healthier, more capable and more loyal teams. When learning and wellbeing come together, workplaces thrive.

References

Indian Council of Medical Research (ICMR) – Workplace Health and Lifestyle Studies
National Family Health Survey (NFHS-5) – Adult Health and Risk Factor Data
World Health Organization (WHO) – Workplace Health Promotion Guidelines
Lancet – Health Education and Behaviour Change Research
NITI Aayog – Workforce Productivity and Preventive Health Reports
EY-FICCI – Corporate Wellness and Employee Engagement Studies

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