• Published on: Feb 06, 2026
  • 3 minute read
  • By: Secondmedic Expert

Severe Headache Not Going Away: Possible Causes, Red Flags, And When To Seek Urgent Care

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Headaches are common, but a severe headache not going away is a different and concerning situation. While many headaches resolve with rest, hydration or medication, persistent severe pain often signals an underlying problem that requires evaluation. Ignoring such headaches can delay diagnosis of serious conditions.

In India, factors such as stress, air pollution, irregular sleep, uncontrolled blood pressure and delayed medical consultation contribute to prolonged headache complaints.

What Does “Severe Headache Not Going Away” Mean?

This refers to:

  • intense head pain lasting more than 48 hours

  • pain that does not respond to usual painkillers

  • headaches that recur daily or worsen

Persistence and severity are key warning features.

Common Causes of a Severe Headache That Persists

Migraine and Status Migrainosus

Migraines cause:

  • throbbing pain

  • nausea

  • light and sound sensitivity

A prolonged migraine lasting more than 72 hours is called status migrainosus and needs medical treatment.

Tension-Type Headaches

Chronic muscle tension causes:

  • band-like pressure

  • neck and scalp tightness

Stress and poor posture worsen symptoms, making headaches persistent.

Sinus Infections

Sinusitis causes:

  • facial pressure

  • pain behind eyes

  • headache worsened by bending

Untreated sinus infections lead to ongoing headaches.

High Blood Pressure

Severely elevated blood pressure may cause:

  • persistent headache

  • head heaviness

  • dizziness

ICMR reports hypertension affects nearly one in four Indian adults.

Medication Overuse Headache

Frequent use of painkillers:

  • alters pain pathways

  • causes rebound headaches

This leads to daily persistent pain.

Infections of the Brain and Coverings

Conditions such as:

  • meningitis

  • encephalitis

cause severe headache with fever, neck stiffness or confusion and are medical emergencies.

Neurological Conditions

Brain tumors, bleeding or raised intracranial pressure may present with:

  • progressively worsening headache

  • morning headaches

  • vomiting

Early detection is critical.

Dehydration and Electrolyte Imbalance

Dehydration causes:

  • reduced blood volume

  • headache and fatigue

Hot climates increase risk of persistent headaches.

Sleep Disorders

Poor sleep quality:

  • lowers pain threshold

  • worsens migraine frequency

Lancet studies show sleep deprivation intensifies headache disorders.

Red Flag Symptoms You Should Not Ignore

Seek immediate medical care if headache is associated with:

  • sudden onset, worst-ever pain

  • fever and neck stiffness

  • confusion or altered consciousness

  • weakness, numbness or speech difficulty

  • vision loss or double vision

  • vomiting without relief

These indicate neurological emergencies.

Impact of Persistent Headache on Daily Life

Ongoing headaches affect:

  • work productivity

  • concentration

  • mood and mental health

  • sleep quality

Chronic pain increases anxiety and depression risk.

Diagnostic Evaluation

Doctors may recommend:

  • blood pressure monitoring

  • blood tests

  • eye examination

  • brain imaging when indicated

Diagnosis depends on history and associated symptoms.

Role of Preventive Health Checkups

Preventive screening helps detect:

  • hypertension

  • metabolic imbalance

  • nutritional deficiencies

Early correction reduces headache recurrence.

Lifestyle Factors That Worsen Headaches

Common contributors include:

  • irregular sleep

  • dehydration

  • skipped meals

  • excessive screen time

  • unmanaged stress

Lifestyle modification is a core part of management.

Management and Treatment Options

Treatment depends on cause and may include:

  • migraine-specific medications

  • antibiotics for infections

  • blood pressure control

  • stress management

  • hydration and sleep correction

Avoid self-medication for persistent headaches.

When Headaches Are Less Likely Serious

Headaches may be less concerning if they:

  • are mild

  • improve with rest

  • have a clear trigger

However, persistence always needs evaluation.

Importance of Early Medical Attention

Delayed evaluation can result in:

  • progression of serious disease

  • avoidable complications

Early diagnosis saves lives and reduces suffering.

Conclusion

A severe headache not going away is a warning sign that should never be ignored. While migraines, sinus infections and stress are common causes, persistent severe headaches may also indicate high blood pressure, infections or neurological emergencies. Recognising red flags, seeking timely medical care and addressing lifestyle factors are essential steps to protect brain health and overall wellbeing.

References

  • Indian Council of Medical Research (ICMR) – Neurological and Hypertension Reports
  • National Family Health Survey (NFHS-5) – Adult Health Indicators
  • World Health Organization (WHO) – Headache Disorders and Red Flags
  • Lancet – Migraine, Sleep and Neurological Health Research
  • NITI Aayog – Preventive Healthcare and Early Symptom Recognition

Read FAQs


A. Any severe headache lasting more than 48 hours or worsening despite medication needs medical evaluation.

A. Yes, chronic stress can trigger tension headaches or migraines, but serious causes must be ruled out.

A. Very high blood pressure can cause persistent headaches and requires urgent assessment.

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Monkeypox

Monkeypox Virus Symptoms: Early Signs, Disease Progression, and When to Seek Care

Monkeypox, now commonly referred to as mpox, is a viral infection that has gained global attention due to outbreaks beyond traditionally affected regions. Understanding monkeypox virus symptoms is essential for early detection, timely isolation and prevention of further spread.

According to the World Health Organization and Indian public health authorities, awareness of symptom patterns plays a critical role in controlling outbreaks and protecting vulnerable populations.

What Is the Monkeypox Virus?

Monkeypox is caused by the monkeypox virus, a member of the Orthopoxvirus family, which also includes smallpox. While generally less severe than smallpox, monkeypox can still cause significant illness and discomfort.

The virus spreads primarily through close physical contact.

 

Incubation Period of Monkeypox

After exposure, symptoms typically appear within:

  • 5 to 21 days

  • most commonly 6 to 13 days

Individuals may feel well during this period but can become infectious once symptoms begin.

 

Early Monkeypox Virus Symptoms

Fever

Fever is usually the first symptom and may be:

  • sudden in onset

  • moderate to high grade

  • accompanied by chills

Fever signals the start of systemic infection.

 

Headache and Body Aches

Patients often experience:

  • severe headache

  • muscle aches

  • back pain

These symptoms resemble many viral illnesses.

 

Fatigue and Weakness

Marked tiredness and low energy levels are common and may limit daily activities.

 

Swollen Lymph Nodes

Swollen lymph nodes are a distinguishing feature of monkeypox.

Common sites include:

  • neck

  • armpits

  • groin

This helps differentiate monkeypox from chickenpox or smallpox.

Development of Monkeypox Rash

The skin rash usually appears:

  • 1 to 3 days after fever onset

It may begin on the face or genital area and spread to other parts of the body.

 

Stages of Monkeypox Rash

The rash progresses through well-defined stages:

Macules

Flat red spots on the skin.

Papules

Raised, firm bumps.

Vesicles

Fluid-filled blisters.

Pustules

Pus-filled lesions that are painful.

Scabs

Lesions crust over and eventually fall off.

Complete healing occurs once scabs detach.

 

Distribution of Rash

Rash commonly affects:

  • face

  • hands and feet

  • mouth

  • genital and anal areas

The number of lesions can vary widely.

 

Pain and Discomfort

Rash lesions may be:

  • painful

  • itchy during healing

Pain severity differs between individuals.

 

Other Possible Symptoms

Additional symptoms may include:

  • sore throat

  • cough

  • nasal congestion

These reflect upper respiratory involvement.

 

Duration of Illness

Monkeypox symptoms typically last:

  • 2 to 4 weeks

Recovery occurs gradually as lesions heal.

 

Who Is at Higher Risk of Severe Illness?

Higher risk groups include:

  • children

  • pregnant women

  • individuals with weakened immunity

  • people with chronic illness

Early care is crucial in these groups.

 

Complications of Monkeypox

Though uncommon, complications may include:

  • secondary bacterial skin infections

  • dehydration

  • pneumonia

  • eye involvement

Prompt medical guidance reduces risk.

 

How Monkeypox Is Transmitted

Transmission occurs through:

  • direct skin-to-skin contact

  • contact with lesions or bodily fluids

  • respiratory droplets during close contact

  • contaminated clothing or bedding

Understanding transmission helps prevent spread.

 

When to Seek Medical Care

Seek medical evaluation if:

  • fever is followed by rash

  • lymph nodes become swollen

  • rash appears in genital or facial areas

Early diagnosis supports isolation and care.

 

Diagnosis and Testing

Diagnosis may involve:

  • clinical examination

  • laboratory testing of lesion samples

Public health authorities guide testing protocols.

 

Prevention and Control Measures

Preventive steps include:

  • avoiding close contact with infected individuals

  • maintaining good hand hygiene

  • isolating during illness

  • following public health guidance

Vaccination may be recommended for high-risk groups.

 

Role of Public Awareness

Awareness of symptoms:

  • enables early detection

  • reduces stigma

  • supports timely care

WHO emphasises community education in outbreak control.

 

Conclusion

Monkeypox virus symptoms typically begin with fever, body aches and swollen lymph nodes, followed by a characteristic rash that progresses through defined stages. While most cases are self-limiting, early recognition, medical evaluation and isolation are essential to prevent complications and reduce transmission. Staying informed and acting promptly protects both individual and public health.

 

References

  • World Health Organization (WHO) – Mpox (Monkeypox) Clinical and Public Health Guidance

  • Indian Council of Medical Research (ICMR) – Emerging Viral Infections Reports

  • National Centre for Disease Control (NCDC), India – Monkeypox Advisories

  • Lancet – Clinical Features and Outcomes of Mpox

  • NITI Aayog – Public Health Preparedness and Infectious Disease Control

See all

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