What is the normal range of SGPT and SGOT?

SGPT (ALT): 7–56 U/L and SGOT (AST): 8–48 U/L. Ranges may slightly vary depending on the lab.

Is fasting required before a liver enzyme test?

Fasting is not always required. Follow your doctor's or diagnostic lab’s instructions.

Which tests should I take for a complete liver check-up?

A full Liver Function Test (LFT) is ideal. It includes SGPT, SGOT, Bilirubin, ALP, GGT, and proteins like Albumin.

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Published on: May 21, 2025
4 minute read
By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

SGPT (ALT) – Serum Glutamic Pyruvic Transaminase
SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

Fatigue or weakness
Yellowing of skin or eyes (jaundice)
Abdominal pain or swelling
Dark urine or pale stools
Alcohol consumption
Hepatitis (A, B, or C)
Obesity or fatty liver
Long-term medication usage
Diabetes or high cholesterol

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

For men: 7 to 56 units per liter of blood
For women: 7 to 45 units per liter

What Does High SGPT Mean?

High SGPT levels may indicate:

Liver inflammation (Hepatitis)
Fatty liver disease
Alcohol-related liver damage
Liver infection or injury
Side effects of medications
Obesity-related liver stress

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

For men: 8 to 48 units per liter of blood
For women: 8 to 43 units per liter

What Does High SGOT Mean?

High SGOT levels may be due to:

Liver damage or cirrhosis
Heart disease or recent heart attack
Muscle injuries
Pancreatitis
Alcohol abuse
Use of certain drugs or supplements

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature	SGPT (ALT)	SGOT (AST)
Location	Mainly in the liver	Liver, heart, kidneys, muscles, brain
Specificity	More liver-specific	Less liver-specific
Indicates	Liver damage	Liver, heart, or muscle damage
Normal Range	7–56 U/L	8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

ALP (Alkaline Phosphatase) – Linked to bile ducts
GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems
Bilirubin – Indicates liver’s ability to process waste
Albumin and Total Protein – Reflects liver's protein production
PT/INR – Measures blood clotting, another liver function

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

Avoid alcohol completely
Maintain a healthy diet (low-fat, high-fiber)
Exercise regularly
Control blood sugar and cholesterol
Stay hydrated

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

Yellow eyes or skin (jaundice)
Severe abdominal pain
Swelling in legs or abdomen
Confusion or mood changes
Dark-colored urine or light-colored stools

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

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Read FAQs

A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

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Reasons Behind Low Haemoglobin in Non-Anaemic People

When people think of low haemoglobin, they often assume it's always linked with anaemia. But that’s not always true. You can have a slightly low haemoglobin count even if your red blood cell count and iron levels are still in the normal range.

So, what does it mean when non-anaemic people have low haemoglobin? Should you worry? Let’s explore the reasons behind low haemoglobin in non-anaemic people and what you can do about it.

What Is Haemoglobin?

Haemoglobin is a protein found in red blood cells that carries oxygen from your lungs to the rest of your body. The average normal levels are:

Men: 13.5 – 17.5 g/dL
Women: 12.0 – 15.5 g/dL

Levels just below the normal range may not be classified as anaemia—but they can still indicate something going on.

Common Reasons for Low Haemoglobin in Non-Anaemic People

1. Mild Nutrient Deficiencies

Even if you’re eating regularly, you could still lack key nutrients needed to build haemoglobin—such as:

Vitamin B12
Folate (Vitamin B9)
Vitamin C (helps absorb iron)

Low levels of these don’t always lead to full-blown anaemia but can reduce haemoglobin production.

2. Chronic Inflammation or Infections

Your body may produce less haemoglobin during periods of chronic inflammation—such as:

Thyroid disorders
IBS or gut issues
Low-grade infections

These may not show symptoms right away but can slightly lower your haemoglobin over time.

3. Dilution from Overhydration

If you drink too much water before a blood test, your blood plasma volume may increase and dilute your haemoglobin, giving a lower reading.

This is temporary and often not harmful, but it can confuse test results.

4. Hormonal Imbalances

Conditions like hypothyroidism can subtly affect red blood cell and haemoglobin production.

In women, heavy menstrual bleeding can cause periodic dips in haemoglobin levels—especially if not supported with iron-rich nutrition.

5. Athletic Training (Pseudo-Anaemia)

In endurance athletes or those who do high levels of cardio, the body increases plasma (fluid) volume to improve circulation. This can lower the haemoglobin concentration without reducing red cell count—this is called athlete’s pseudo-anaemia.

What Tests to Consider

If you have low haemoglobin but no signs of anaemia, your doctor may recommend:

Serum Ferritin (iron storage)
Vitamin B12 and Folate tests
Thyroid profile
CRP or ESR (for inflammation)

You can get these tests easily with home sample collection from trusted platforms like SecondMedic.com, powered by Thyrocare.

Should You Be Concerned?

If your haemoglobin is:

Slightly below normal (e.g., 11.8–12.2 g/dL)
You have no symptoms (fatigue, paleness, breathlessness)

…then it may not be an emergency. However, monitoring and lifestyle changes are still important.

If it drops further or if symptoms appear, consult a doctor immediately.

What You Can Do Naturally

Improve Your Diet

Eat leafy greens, legumes, citrus fruits
Add iron-rich foods like beetroot, dates, and jaggery
Pair iron with vitamin C (e.g., lemon + spinach)

Reduce Inflammation

Avoid excessive sugar, fried foods, and processed meals
Include turmeric, ginger, and antioxidants in your diet

Stay Active but Balanced

Don’t overtrain
Rest and hydrate well, especially before blood tests

Conclusion

Low haemoglobin without anaemia is more common than you might think. The causes are often mild and reversible, but keeping an eye on your numbers and adjusting your diet or lifestyle can make a big difference.

If you’ve been wondering about the reasons behind low haemoglobin in non-anaemic people, now you know how to understand and manage it better—naturally and confidently.

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