• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Do Late-Night Meals Cause Weight Gain

Do Late-Night Meals Cause Weight Gain? Let’s Uncover the Truth

Many of us have a habit of snacking late at night or even having a full meal right before bed. Whether it’s a busy schedule, late-night cravings, or watching movies with snacks, eating late has become quite common. But the big question is—do late-night meals cause weight gain?

Let’s explore what science says, how your body responds to late meals, and tips to manage your eating habits for better health and weight control.

 

Why We Eat Late at Night

In today’s fast-paced life, late-night eating often happens because of:

  • Long working hours or night shifts
     

  • Skipping meals during the day
     

  • Emotional eating or stress
     

  • Social gatherings or weekend habits
     

While occasional late-night eating may not harm you, making it a routine could have consequences—especially if the food choices aren’t healthy.

 

How Your Body Works While You Sleep

Your body doesn’t shut down at night—it continues working. However, the metabolism slows down because your body prepares for rest, not digestion. Late-night meals, especially heavy or sugary ones, are digested more slowly.

During sleep, your energy demand is low, so the extra calories consumed at night are more likely to be stored as fat rather than burned for energy.

 

Late-Night Eating and Weight Gain: What's the Link?

Several studies show that when you eat is just as important as what you eat. Here’s why eating late may contribute to weight gain:

Calorie Surplus

Late-night meals usually come after you've already eaten enough during the day. So, you’re adding more calories than your body needs—leading to weight gain.

Poor Food Choices

People tend to eat unhealthy foods at night—like chips, ice cream, sugary drinks, or fast food. These high-calorie items with little nutrition easily lead to fat storage.

Hormonal Imbalance

Late eating can affect hormones like insulin, leptin, and ghrelin, which regulate hunger and fat storage. Disrupted hormonal patterns can make you feel hungrier the next day and crave more junk food.

Disrupted Sleep

Heavy meals before bed can cause bloating, acidity, or indigestion—leading to poor sleep. Poor sleep affects metabolism, increases hunger hormones, and makes weight gain more likely.

 

Common Myths About Late-Night Eating

Let’s bust a few myths:

Myth: Eating after 8 PM always causes weight gain.
Fact: It depends on how much and what you eat. A light snack at 9 PM is very different from a greasy burger at midnight.

Myth: Your body stores everything as fat at night.
Fact: If your total daily calories are under control and your food choices are healthy, you won’t automatically gain weight.

 

When Late-Night Meals Might Be Okay

Late-night eating isn’t always harmful—especially if:

  • You’ve had a long gap between meals
     

  • You're genuinely hungry (not just bored)
     

  • You choose a light and balanced snack like:
     

    • A handful of almonds
       

    • Greek yogurt
       

    • A banana or boiled egg
       

    • Warm turmeric milk
       

These foods are low in calories and promote better sleep.

 

Best Time to Eat Dinner

Nutrition experts recommend having your last major meal 2 to 3 hours before bedtime. For example, if you sleep at 10:30 PM, aim to finish dinner by 7:30–8:00 PM.

This gives your body enough time to digest food before you lie down, preventing bloating, heartburn, and excess fat storage.

 

Tips to Avoid Late-Night Overeating

Here’s how to manage your night-time hunger:

1. Eat Balanced Meals During the Day

Don’t skip breakfast or lunch. When you eat regularly, you’re less likely to feel hungry late at night.

2. Hydrate Properly

Thirst is often mistaken for hunger. Drink water before reaching for a snack.

3. Plan Your Dinner Time

Set a regular time for dinner. Make it a light, protein-rich meal with veggies.

4. Don’t Eat Out of Boredom

Keep yourself busy. Sometimes a walk, a warm shower, or reading helps more than food.

5. Sleep on Time

Late sleepers are more likely to snack. A fixed sleep schedule helps control hunger hormones.

 

Healthy Late-Night Snack Ideas

If you truly need something to eat before bed, try:

  • Low-fat yogurt
     

  • Whole-grain crackers with peanut butter
     

  • A small fruit like apple or kiwi
     

  • Herbal teas like chamomile or tulsi
     

Avoid spicy, fried, or sugary foods—they’ll disrupt sleep and digestion.

 

What You Can Do for Weight Control

If you're struggling with weight or digestion, consider a weight management test panel. Thyrocare (via SecondMedic) offers:

  • Thyroid test – to rule out hormonal causes
     

  • Vitamin & lipid profile – for metabolic insight
     

  • Fasting glucose & HbA1c – for sugar levels
     

These tests help identify if late-night eating is affecting your metabolism or sugar levels.

 

Conclusion

So, do late-night meals cause weight gain? The answer depends on what, how much, and how often you eat late at night. Eating a heavy or high-calorie meal before bed regularly can absolutely lead to weight gain over time.

The key is to eat mindfully, stick to healthy choices, and maintain a consistent eating and sleeping schedule. Occasional late-night snacks won’t hurt—but turning them into a habit will.

To protect your health and manage weight, be aware of what you eat, and when you eat—because yes, do late-night meals cause weight gain? Absolutely, if you're not careful.

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