• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Is it Allergy or Asthma

Is it Allergy or Asthma? How to Know the Difference

Have you ever found yourself sneezing, coughing, or gasping for air and wondering whether it's just a seasonal allergy or something more serious like asthma? You're not alone. Many people confuse the symptoms of allergies and asthma because they often overlap. However, knowing the difference between the two is crucial for getting the right treatment and managing your condition effectively.

In this blog, we’ll explain what allergies and asthma are, how they’re related, what makes them different, and how to know what you’re dealing with.

 

What Are Allergies?

Allergies happen when your immune system reacts to a harmless substance like pollen, dust, or pet dander as if it were dangerous. These substances are called allergens. When you're exposed to an allergen, your body releases chemicals like histamine that cause allergy symptoms.

Common Allergy Symptoms:

  • Sneezing

  • Runny or stuffy nose

  • Itchy eyes, nose, or throat

  • Watery eyes

  • Skin rashes or hives

  • Coughing (especially at night)

  • Fatigue
     

These symptoms usually appear quickly after exposure to the allergen and can range from mild to severe.

 

What Is Asthma?

Asthma is a chronic lung disease that inflames and narrows your airways, making it hard to breathe. Asthma can be triggered by many things—including allergens. When asthma flares up, it’s called an asthma attack or asthma episode.

Common Asthma Symptoms:

  • Shortness of breath

  • Chest tightness or pain

  • Wheezing (a whistling sound when breathing)

  • Coughing (often worse at night or early morning)

  • Trouble sleeping due to breathing issues
     

Asthma symptoms can come and go. They may be triggered by allergens, cold air, exercise, smoke, or even stress.

 

Are Allergies and Asthma Related?

Yes, they are! Many people who have allergies also have asthma. This condition is called allergic asthma. In fact, allergens like pollen, mold, pet dander, and dust mites are common asthma triggers.

When you breathe in something you're allergic to, your airways can become inflamed, making it difficult to breathe—this is where allergies and asthma overlap.

 

Key Differences Between Allergy and Asthma

Feature

Allergy

Asthma

Affects

Eyes, nose, throat, skin

Lungs and airways

Symptoms

Sneezing, itching, watery eyes, rashes

Wheezing, breathlessness, chest tightness

Trigger

Pollen, dust, food, pets, etc.

Allergens, exercise, cold air, pollution

Time of Symptoms

Immediate (within minutes)

May develop slowly or suddenly

Treatment Focus

Antihistamines, avoiding allergens

Inhalers, bronchodilators, steroids

While allergies mostly affect the upper airways (like your nose and throat), asthma affects the lower airways (your lungs).

 

How to Know What You Have

1. Track Your Symptoms

Keep a journal of what symptoms you experience, when they occur, and what you were doing at the time. Are you only sneezing and sniffling when the pollen count is high? Do you wheeze and cough after jogging or being around pets?

2. Get Allergy Testing

Your doctor may recommend a blood test or skin prick test to find out what you’re allergic to. This is especially helpful if your symptoms are triggered by specific things like pollen or food.

3. Do a Lung Function Test (Spirometry)

This simple breathing test helps measure how well your lungs work. If you have asthma, the test may show that your airways are narrowed or inflamed. The results also help doctors decide how severe your asthma is.

4. Observe When Symptoms Occur

If your symptoms occur mostly in certain seasons (like spring or fall), they may be due to allergies. If they happen during exercise or at night, it could be asthma.

 

Can You Have Both?

Absolutely. Many people live with both allergies and asthma. In these cases, managing one helps manage the other. For example, taking allergy medication can help reduce asthma symptoms triggered by allergens.

That’s why it's important to get a proper diagnosis. Treating only one condition when you have both may not bring full relief.

 

Treatment Options

For Allergies:

  • Antihistamines – reduce sneezing and itching

  • Nasal sprays – ease a runny or blocked nose

  • Eye drops – soothe itchy, watery eyes

  • Allergy shots (immunotherapy) – gradually reduce your sensitivity to allergens
     

For Asthma:

  • Inhalers – deliver medicine directly to the lungs

  • Long-term medications – reduce airway inflammation

  • Rescue inhalers – for quick relief during an attack

  • Lifestyle changes – avoid triggers, keep your environment clean
     

Always consult a doctor before starting any treatment.

 

When to See a Doctor

You should see a healthcare provider if:

  • You have trouble breathing or frequent coughing

  • Symptoms interfere with daily life or sleep

  • Over-the-counter allergy medicine isn’t helping

  • You need to use your asthma inhaler more often than usual
     

Early diagnosis and treatment can prevent complications and improve your quality of life.

 

Final Thoughts

Understanding the difference between allergies and asthma is the first step in managing your health. Both are common, manageable conditions—but only if you know what you're dealing with. By observing your symptoms and getting tested, you can find the right path to relief.

 

Conclusion: Is it Allergy or Asthma? How to Know the Difference

If you're asking yourself, "Is it allergy or asthma? How to know the difference," the answer lies in understanding your symptoms, knowing your triggers, and getting the right tests done. Don’t guess—get tested through trusted services like SecondMedic and take control of your breathing and well-being today!

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