• Published on: May 21, 2025
  • 4 minute read
  • By: Secondmedic Expert

Liver Enzymes Test Explained – What SGPT/SGOT Mean

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The liver is one of the most important organs in your body. It performs hundreds of functions, including filtering toxins, producing bile, and supporting digestion and metabolism. When your liver is under stress or not functioning properly, certain enzymes in your blood can increase. Two of the most common enzymes tested are SGPT (ALT) and SGOT (AST). In this blog, we will break down what these enzymes mean, why your doctor might suggest this test, and what the results indicate.

What is a Liver Enzymes Test?

A liver enzymes test is a type of blood test used to evaluate the health of your liver. It measures specific proteins (called enzymes) that the liver releases into your blood. When liver cells are damaged, these enzymes leak into your bloodstream. The most commonly tested liver enzymes are:

  • SGPT (ALT) – Serum Glutamic Pyruvic Transaminase

  • SGOT (AST) – Serum Glutamic Oxaloacetic Transaminase
     

Why Do Doctors Recommend a Liver Enzymes Test?

Your doctor may ask for a liver enzymes test if you show symptoms of liver problems or are at risk due to lifestyle or existing health conditions. Some common reasons include:

  • Fatigue or weakness

  • Yellowing of skin or eyes (jaundice)

  • Abdominal pain or swelling

  • Dark urine or pale stools

  • Alcohol consumption

  • Hepatitis (A, B, or C)

  • Obesity or fatty liver

  • Long-term medication usage

  • Diabetes or high cholesterol
     

What is SGPT (ALT)?

SGPT, also known as ALT (Alanine Aminotransferase), is an enzyme mainly found in the liver. It plays a role in converting proteins into energy for liver cells. When liver cells are damaged or inflamed, SGPT leaks into the bloodstream.

Normal SGPT Levels:

  • For men: 7 to 56 units per liter of blood

  • For women: 7 to 45 units per liter
     

What Does High SGPT Mean?

High SGPT levels may indicate:

  • Liver inflammation (Hepatitis)

  • Fatty liver disease

  • Alcohol-related liver damage

  • Liver infection or injury

  • Side effects of medications

  • Obesity-related liver stress
     

Sometimes, even intense physical activity or certain supplements can temporarily raise SGPT levels.

What is SGOT (AST)?

SGOT, also known as AST (Aspartate Aminotransferase), is an enzyme found not just in the liver, but also in the heart, kidneys, muscles, and brain. So, while it can point to liver damage, it may also indicate problems in other organs.

Normal SGOT Levels:

  • For men: 8 to 48 units per liter of blood

  • For women: 8 to 43 units per liter
     

What Does High SGOT Mean?

High SGOT levels may be due to:

  • Liver damage or cirrhosis

  • Heart disease or recent heart attack

  • Muscle injuries

  • Pancreatitis

  • Alcohol abuse

  • Use of certain drugs or supplements
     

If both SGPT and SGOT are elevated, it’s more likely to be a liver-related issue.

SGPT vs SGOT – What's the Difference?

Feature

SGPT (ALT)

SGOT (AST)

Location

Mainly in the liver

Liver, heart, kidneys, muscles, brain

Specificity

More liver-specific

Less liver-specific

Indicates

Liver damage

Liver, heart, or muscle damage

Normal Range

7–56 U/L

8–48 U/L

Conclusion: If only SGPT is high, it's more likely to be liver-specific. If both are high, the doctor may run further tests.

Other Liver Tests Often Done Together

To get a full picture of liver health, doctors may also recommend:

  • ALP (Alkaline Phosphatase) – Linked to bile ducts

  • GGT (Gamma-Glutamyl Transferase) – Linked to alcohol use or bile problems

  • Bilirubin – Indicates liver’s ability to process waste

  • Albumin and Total Protein – Reflects liver's protein production

  • PT/INR – Measures blood clotting, another liver function
     

What to Do if SGPT/SGOT Are High?

If your test results show high liver enzymes, don’t panic. A one-time elevation doesn’t always mean serious disease. Here's what you should do:

1. Follow-Up Testing

Your doctor may repeat the test after a few weeks or recommend imaging (ultrasound/CT scan) to check for liver fat, fibrosis, or tumors.

2. Lifestyle Changes

  • Avoid alcohol completely

  • Maintain a healthy diet (low-fat, high-fiber)

  • Exercise regularly

  • Control blood sugar and cholesterol

  • Stay hydrated
     

3. Review Medications

Some over-the-counter drugs like paracetamol, or supplements like bodybuilding products, can raise liver enzymes.

4. Monitor Regularly

If you have a chronic condition like diabetes, high cholesterol, or obesity, make liver function tests part of your routine health checks.

When to See a Doctor Immediately

  • Yellow eyes or skin (jaundice)

  • Severe abdominal pain

  • Swelling in legs or abdomen

  • Confusion or mood changes

  • Dark-colored urine or light-colored stools
     

These signs may indicate serious liver issues and need immediate attention.

Final Thoughts

The liver is a silent warrior – it works 24/7 and rarely complains until it's seriously damaged. That’s why regular check-ups, especially liver enzyme tests, are essential for early detection and prevention.

Understanding your SGPT and SGOT levels can give you valuable insights into your liver’s health. Whether you’re dealing with symptoms, managing a chronic condition, or just doing a preventive health check, this simple blood test can help you stay one step ahead.

Call to Action

Worried about your liver health? Book a full liver function test online today and get your results from the comfort of your home. Know your SGPT and SGOT levels now – because your health can’t wait.

Liver Enzymes Test Explained – What SGPT/SGOT Mean – Book Now on SecondMedic.com!

Read FAQs


A. It helps diagnose liver diseases, monitor liver health, and assess the impact of medications, alcohol, or infections on the liver.

A. SGPT (ALT): 7–56 U/L SGOT (AST): 8–48 U/L Ranges may vary slightly based on labs.

A. Elevated levels may indicate liver inflammation, fatty liver, hepatitis, alcohol-related damage, or side effects from medications.

A. Fasting is not always required, but it's best to follow your doctor’s or lab’s instructions.

A. A Liver Function Test (LFT), which includes SGPT, SGOT, Bilirubin, ALP, GGT, Albumin, and Total Protein, is recommended.

Read Blog
Chronic Stress Affects Your Digestive Health

How Chronic Stress Affects Your Digestive Health – Understanding the Gut-Stress Connection

Introduction:

In today’s fast-paced world, stress has become a constant companion. From work pressures to personal challenges, chronic stress can take a serious toll on your health. While most people are aware of how stress can affect mental well-being, many don't realize its powerful impact on physical health — especially the digestive system. Yes, your gut and brain are more connected than you think. In this blog, we’ll explore how chronic stress affects your digestive health, the science behind it, symptoms to watch for, and simple tips to protect your gut.

 

What Is Chronic Stress?

Stress is the body’s natural response to pressure or danger. It can be helpful in short bursts (like escaping danger), but when it becomes ongoing — known as chronic stress — it can harm your body over time.

Chronic stress arises when you constantly feel overwhelmed or unable to cope with the demands of daily life. This continuous stress activates your body’s fight-or-flight response, keeping your system on high alert.

 

The Gut-Brain Connection

Your gut and brain are linked through a complex communication network known as the gut-brain axis. This system connects your central nervous system (brain and spinal cord) with your enteric nervous system (gut nerves).

  • The vagus nerve, one of the largest nerves in the body, plays a big role in this communication.

  • Neurotransmitters like serotonin (which affects mood) are produced in the gut.

  • Your gut bacteria (microbiome) also influence brain function and stress levels.
     

This two-way relationship means stress can affect your gut — and gut issues can impact your mood.

 

How Chronic Stress Affects Your Digestive Health

Let’s break down exactly what happens to your digestive system when you’re under long-term stress.

 

1. Slows Down Digestion

When you’re stressed, your body shifts energy away from digestion to prioritize “survival.” This means food may sit longer in your stomach, leading to:

  • Bloating

  • Gas

  • Indigestion

  • Heartburn

 

2. Triggers or Worsens Irritable Bowel Syndrome (IBS)

People with IBS often report that stress worsens their symptoms. Chronic stress may:

  • Increase abdominal pain

  • Trigger diarrhea or constipation

  • Create irregular bowel habits

 

3. Changes Gut Bacteria

Stress can harm the balance of healthy bacteria in your gut, known as the microbiome. A disrupted microbiome can lead to:

  • Inflammation

  • Weakened immune system\

  • Poor nutrient absorption

  • Increased risk of leaky gut

 

4. Reduces Blood Flow to Digestive Organs

Stress can narrow blood vessels, reducing circulation to your gut. This can affect digestion and nutrient uptake and even cause nausea.

 

5. Affects Appetite and Eating Habits

Chronic stress can lead to:

  • Overeating or binge-eating (stress eating)

  • Loss of appetite

  • Cravings for unhealthy, sugary, or fatty foods
     

Both overeating and undereating can negatively impact digestion and gut health.

 

Common Digestive Symptoms of Chronic Stress

If you’re frequently stressed, you may notice signs like:

  • Frequent stomachaches

  • Nausea or vomiting

  • Constipation or diarrhea

  • Acid reflux or heartburn

  • Unexplained bloating

  • Feeling full too soon or loss of appetite
     

These symptoms shouldn’t be ignored — your body is trying to tell you something.

 

Tips to Protect Your Digestive Health During Stress

Now that we know how chronic stress affects your digestive health, let’s look at practical ways to manage stress and support your gut.

 

1. Practice Mindfulness and Relaxation

  • Try deep breathing, meditation, or progressive muscle relaxation.

  • Even 10 minutes a day can calm your nervous system.

 

2. Eat Gut-Friendly Foods

  • Add probiotics (like yogurt, kefir, and kimchi) to improve gut flora.

  • Eat fiber-rich foods like fruits, vegetables, and whole grains.

  • Stay hydrated.

 

3. Exercise Regularly

  • Physical activity reduces stress hormones and boosts mood.

  • Aim for at least 30 minutes of moderate exercise most days.

 

4. Sleep Well

  • Poor sleep increases stress and harms digestion.

  • Stick to a routine: 7–9 hours of sleep per night.
     

5. Talk It Out

  • Don’t bottle things up — speak with a friend, family member, or therapist.

  • Stress management often starts with emotional release.
     

6. Limit Caffeine and Alcohol

  • These can irritate the stomach and worsen stress levels.

  • Opt for herbal teas or warm water with lemon.

 

When to See a Doctor

If your digestive symptoms persist even after stress management techniques, it’s important to consult a healthcare professional. Conditions like ulcers, IBS, or food intolerances may need medical attention.

 

Final Thoughts

Your gut and mind are deeply connected. What you feel mentally can show up physically — especially in your digestive system. By understanding this link, you can take steps to reduce stress and improve both your mental and gut health. A balanced lifestyle, rich diet, and mindfulness can make a huge difference in your well-being.

 

Conclusion

Ignoring stress doesn't just affect your mood — it disrupts your digestion, weakens your immunity, and decreases your quality of life. So take charge today: breathe deeply, eat well, and be kind to your body. Because now you know exactly how chronic stress affects your digestive health.

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