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Published on: Apr 04, 2020
1 minute read
By: Raj Dwivedi

Good News Around Corona Virus On Friday Everyone Missed!

· On Friday FDA announced an emergency authorization of a Roche Holding AG test that can screen patients much faster than all existing options.

· The biggest impact of these tests would be that it would help catch up on the all the tests which are on queue currently.

· What very few have realized that our inability to test enough people fast enough has led to an outbreak that is likely to spin out of control in the weeks to come. If that happens then we won’t be able to contain things any time soon.

· More than lab tests we need “serologic tests” and “on-site diagnostics” which can play a crucial role in helping to better estimate the size of the problem (outbreak) and exercise necessary control to prevent the spread.

· Serologic diagnostics allow extensive testing of samples from people who aren’t confirmed COVID-19 cases.

· The best thing is that If people have been exposed and have developed antibodies against the virus, such tests will let health officials in frontline know much faster.

· This is invaluable information in the fight against a disease that is mild or asymptomatic in many people.

· It will bring some key KPIs to limelight in addition to giving a better sense of how many cases we’re missing and COVID-19’s true fatality rate, it could also identify areas where it is spreading more quietly and help direct needed response.

· Centres for Disease Control Director Robert Redfield recently told a Congressional committee that his agency has two tests of this type in development.

· This fast deployment is critical piece around the globe as there simply isn’t any reliable information on where we stand at any time and where the disease is and how many people have it.

· Another important step would involve moving testing capabilities out of the lab and into doctors’ offices.

· Ideally, providers should be able to order and run tests rapidly on site similar to the flu instead of sending them off to an overtaxed lab and lowering risk of infection

· An accurate and quick test of this type would mean that fewer people are left hanging in limbo about their actual infection status, expediting isolation, monitoring, and treatment efforts.

· People could be diagnosed in a far broader array of settings, lowering the risk of further spread of infection and keeping them out of hospitals that could spend more of their time totally focused to severe cases.

· A wider range of diagnostics would enable more targeted monitoring and reduce the need for blanket travel bans and other economically harmful containment measures. We hope that all support would get these tests approved and distributed quickly.

So in summary the approach is in a good direction and agility around diagnosis will get us ahead of things while we’re still only in the early stages of this outbreak.

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Monkeypox Virus Symptoms: Early Signs, Disease Progression, and When to Seek Care

Monkeypox, now commonly referred to as mpox, is a viral infection that has gained global attention due to outbreaks beyond traditionally affected regions. Understanding monkeypox virus symptoms is essential for early detection, timely isolation and prevention of further spread.

According to the World Health Organization and Indian public health authorities, awareness of symptom patterns plays a critical role in controlling outbreaks and protecting vulnerable populations.

What Is the Monkeypox Virus?

Monkeypox is caused by the monkeypox virus, a member of the Orthopoxvirus family, which also includes smallpox. While generally less severe than smallpox, monkeypox can still cause significant illness and discomfort.

The virus spreads primarily through close physical contact.

Incubation Period of Monkeypox

After exposure, symptoms typically appear within:

5 to 21 days
most commonly 6 to 13 days

Individuals may feel well during this period but can become infectious once symptoms begin.

Early Monkeypox Virus Symptoms

Fever

Fever is usually the first symptom and may be:

sudden in onset
moderate to high grade
accompanied by chills

Fever signals the start of systemic infection.

Headache and Body Aches

Patients often experience:

severe headache
muscle aches
back pain

These symptoms resemble many viral illnesses.

Fatigue and Weakness

Marked tiredness and low energy levels are common and may limit daily activities.

Swollen Lymph Nodes

Swollen lymph nodes are a distinguishing feature of monkeypox.

Common sites include:

neck
armpits
groin

This helps differentiate monkeypox from chickenpox or smallpox.

Development of Monkeypox Rash

The skin rash usually appears:

1 to 3 days after fever onset

It may begin on the face or genital area and spread to other parts of the body.

Stages of Monkeypox Rash

The rash progresses through well-defined stages:

Macules

Flat red spots on the skin.

Papules

Raised, firm bumps.

Vesicles

Fluid-filled blisters.

Pustules

Pus-filled lesions that are painful.

Scabs

Lesions crust over and eventually fall off.

Complete healing occurs once scabs detach.

Distribution of Rash

Rash commonly affects:

face
hands and feet
mouth
genital and anal areas

The number of lesions can vary widely.

Pain and Discomfort

Rash lesions may be:

painful
itchy during healing

Pain severity differs between individuals.

Other Possible Symptoms

Additional symptoms may include:

sore throat
cough
nasal congestion

These reflect upper respiratory involvement.

Duration of Illness

Monkeypox symptoms typically last:

2 to 4 weeks

Recovery occurs gradually as lesions heal.

Who Is at Higher Risk of Severe Illness?

Higher risk groups include:

children
pregnant women
individuals with weakened immunity
people with chronic illness

Early care is crucial in these groups.

Complications of Monkeypox

Though uncommon, complications may include:

secondary bacterial skin infections
dehydration
pneumonia
eye involvement

Prompt medical guidance reduces risk.

How Monkeypox Is Transmitted

Transmission occurs through:

direct skin-to-skin contact
contact with lesions or bodily fluids
respiratory droplets during close contact
contaminated clothing or bedding

Understanding transmission helps prevent spread.

When to Seek Medical Care

Seek medical evaluation if:

fever is followed by rash
lymph nodes become swollen
rash appears in genital or facial areas

Early diagnosis supports isolation and care.

Diagnosis and Testing

Diagnosis may involve:

clinical examination
laboratory testing of lesion samples

Public health authorities guide testing protocols.

Prevention and Control Measures

Preventive steps include:

avoiding close contact with infected individuals
maintaining good hand hygiene
isolating during illness
following public health guidance

Vaccination may be recommended for high-risk groups.

Role of Public Awareness

Awareness of symptoms:

enables early detection
reduces stigma
supports timely care

WHO emphasises community education in outbreak control.

Conclusion

Monkeypox virus symptoms typically begin with fever, body aches and swollen lymph nodes, followed by a characteristic rash that progresses through defined stages. While most cases are self-limiting, early recognition, medical evaluation and isolation are essential to prevent complications and reduce transmission. Staying informed and acting promptly protects both individual and public health.

References

World Health Organization (WHO) – Mpox (Monkeypox) Clinical and Public Health Guidance
Indian Council of Medical Research (ICMR) – Emerging Viral Infections Reports
National Centre for Disease Control (NCDC), India – Monkeypox Advisories
Lancet – Clinical Features and Outcomes of Mpox
NITI Aayog – Public Health Preparedness and Infectious Disease Control

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