Q. What is the explanation for allergies?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Allergies are immune responses that occur when the immune system reacts excessively to substances that are typically harmless to most individuals. These substances, known as allergens, can include pollen, dust mites, pet dander, certain foods, insect venom, and various chemicals. When a person with allergies comes into contact with an allergen, their immune system perceives it as a threat and launches an inappropriate defensive response.
The immune response in allergies involves the production of antibodies called immunoglobulin E (IgE). These antibodies attach to specialized cells called mast cells and basophils, which are found in tissues throughout the body, particularly in areas like the respiratory tract, skin, and digestive system. Upon subsequent exposure to the same allergen, the allergen binds to the IgE antibodies on these cells, triggering the release of various chemicals, including histamine. This release of chemicals leads to the typical symptoms of an allergic reaction.
Common allergic reactions can manifest in various ways, such as:
Respiratory Symptoms: These can include sneezing, runny or congested nose, itchy or watery eyes, coughing, wheezing, and shortness of breath. These reactions often occur due to airborne allergens like pollen or pet dander.
Skin Symptoms: Skin reactions can result in itching, hives (raised, itchy welts on the skin), eczema (inflamed, itchy skin), and swelling. Contact with substances like certain plants, chemicals, or certain foods can trigger these responses.
Gastrointestinal Symptoms: Allergies can lead to nausea, vomiting, abdominal pain, and diarrhea when certain allergenic foods are ingested.
Anaphylaxis: In severe cases, exposure to allergens can cause a rapid and severe allergic reaction known as anaphylaxis. This is a medical emergency and can lead to symptoms like difficulty breathing, a drop in blood pressure, and loss of consciousness. Anaphylaxis requires immediate medical attention.
The exact reasons why some individuals develop allergies while others do not are not entirely understood. Genetics play a role, as allergies tend to run in families. Additionally, environmental factors and early life exposures can influence the development of allergies. For example, exposure to allergens at a young age might increase the likelihood of developing allergies.
Allergies can range from mild discomfort to life-threatening situations, so it's important for individuals with known allergies to manage their condition through allergen avoidance, medications like antihistamines and corticosteroids, and, in the case of severe allergies, carrying epinephrine injectors to counteract severe reactions. Allergy testing conducted by medical professionals can help identify specific allergens, allowing for more targeted avoidance strategies.
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