- Published on: Apr 17, 2020
- 4 minute read
- By: Dr Rajan Choudhary
Vitamin D In Reducing The Risk Of COVID 19
Why Vitamin D is the only supplement we will recommend for you.
Most of our blogs have looked at theories posted on social media, and shown how they are usually not true, or have no factual basis behind them. But here we will show some evidence that supports something truly interesting, especially during the time of this pandemic.
For a number of years research has shown a possible link between vitamin D and illnesses, specifically respiratory infections. In our previous blogs we have shown that vitamin supplementation is unnecessary, except for vitamin D. Here we will show why supplementation may be in your best interest for reducing the risk of COVID.
Now I’ll be honest. Vitamin D and immunity was not something we were taught at medical school, or in medical practice. The fact that such a large amount of research exists on this topic is certainly interesting, and whilst researching this topic I have certainly learnt a lot myself, enough to change my own medical practice. And it is because of the high quality of evidence present that I feel confident in supporting the claims below.
SUMMARY
- Many people are low in Vitamin D due to various risk factors (see our blog on vitamin D)
- Vitamin D appears to have a role in modulating immune function
- Low Vitamin D levels appear to increase the severity of autoimmune disorders
- Low Vitamin D levels appear to increase the risk of getting respiratory infections
- Vitamin D supplementation appears to reduce the risk of getting respiratory infections
- Those who are at risk of having low vitamin D should take low dose supplementations.
If you want the good stuff, skip to the section on SUPPLEMENTATION
IMMUNE FUNCTIONS
As we’ve discussed, vitamin D is key in maintaining the right balance of calcium, ensuring the right amount is taken up from the food we eat, integrated into our bones, and removed in our urine if not required. We know that there are some people who are at risk of vitamin D deficiency, and this is more common in countries closer to the poles and with cloudy weather.
But there also appears to be a role for vitamin D in modulating the immune system. We have found many more cells in our body other than bone, intestine and kidney that possess the vitamin D receptor. These include immune cells, and one role may be to promote proliferation of these cells as well as promote their protective immunity.
AUTOIMMUNE
Due to its role in immune function, studies have been performed to see whether there is a link between autoimmune diseases and vitamin D. Common autoimmune disorders (and the organs the affect) include multiple sclerosis (nerves), rheumatoid arthritis (joints), diabetes mellitus (pancreas), inflammatory bowel disease (bowels) and systemic lupus erythematous (the entire body). All of these diseases lead to loss in function of an organ or system as the immune system recognises the organ as an “invader” and begins to destroy it.
One study looked at 161 patients with early forms of autoimmune diseases over 2 years. Out of them, 35 went on to develop full blown autoimmune disorders (like rheumatoid and lupus). Whilst the two groups of patients were mostly similar, vitamin D was noticeably lower in the group that progressed to disease. But this is one study, with a small number of patients.
Other studies have looked at vitamin D levels in patients across the globe, and the majority of them have shown there to be a correlation between low vitamin D or severe deficiency, and the severity of autoimmune disorder they have. We will not go into them in detail because this is beyond the scope of this blog, but it certainly is interesting and supports this new role for vitamin D.
RESPIRATORY INFECTIONS
We have unknowingly tried to use Vitamin D to treat infections prior to the advent of antibiotics. A common treatment for tuberculosis was to send patients to sanatoriums, where treatments included exposure to sunlight, and provision of cod liver oil, a rich source of vitamin D.
Large population studies done in the 1980s and 1990s involving 19,000 people showed that those with low vitamin D levels were more likely to self report recent upper respiratory tract infections than those with normal levels. This was true even if age, gender, season and race were accounted for. Similar studies have shown similar results when looking at rates of influenza, bacterial vaginosis and HIV.
Normally we are very skeptical with such studies, and look for weaknesses in their methodology and conclusions. After all, we could just cherry pick the studies that show a benefit. Furthermore, just because there is a trend with vitamin D levels and infection, this does not imply a direct link. More evidence is required. However, the fact 19,000 people were surveyed provides this study with good statistical power, and lends it validity. But lets look for more.
SUPPLEMENTATION
Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data – Martineau 2017, British Medical Journal
A systematic review and meta analysis is the highest level of evidence in the realm of medical research. It is the absolute pinnacle of thorough research, looking and comparing other studies with very close scrutiny to see whether we have conducted enough research worldwide to support a theory. In this case this systematic review was published in the British Medical Journal, a highly reputable source that again scrutinises any study submitted thoroughly before accepting it for publication. In my eyes, this is some of the best evidence we will have on this topic. And it is a far sight better than any WhatsApp forwards.
So what does this say?
Vitamin D supplementation was safe and it protected against acute respiratory tract infection overall. Patients who were very vitamin D deficient and those not receiving bolus doses experienced the most benefit.
I don’t think I could have summarised it better myself. If you wish to read the study yourself you can use this link: https://www.bmj.com/content/356/bmj.i6583 Vitamin D supplementation to prevent acute respiratory tract infections
WHAT DOES THIS MEAN FOR ME?
If you are someone who may be at risk of vitamin D deficiency, then low dose supplements (NOT treatment dose) may be beneficial in reducing the risk of getting a respiratory infection. Since COVID is caused by a respiratory virus, we can extrapolate that Vitamin D supplementations may reduce your risk of getting COVID. This is not a cure, and it is not a guaranteed protection. If you already have a balanced diet and are not low in Vit D, it may be less beneficial.
Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc
www.secondmedic.com
Vitamin D Deficiency Symptoms: Signs Your Body May Be Lacking Vitamin D
Vitamin D is an essential nutrient that plays a vital role in maintaining strong bones, supporting the immune system and regulating several important functions in the body. Despite its importance, vitamin D deficiency is one of the most common nutritional deficiencies worldwide.
In India, vitamin D deficiency has become increasingly prevalent due to lifestyle factors such as limited sunlight exposure, indoor working environments and dietary habits. According to the Indian Council of Medical Research (ICMR), a significant percentage of the population may have insufficient vitamin D levels.
Recognizing the symptoms of vitamin D deficiency early is important because prolonged deficiency can lead to serious health complications affecting bones, muscles and overall wellbeing.
What Is Vitamin D and Why Is It Important?
Vitamin D is often called the “sunshine vitamin” because the body produces it when the skin is exposed to sunlight. It plays a key role in calcium absorption, which is essential for maintaining healthy bones and teeth.
In addition to bone health, vitamin D supports several important functions including:
immune system regulation
muscle function
inflammation control
hormonal balance
Low levels of vitamin D can disrupt these functions and contribute to various health problems.
Common Symptoms of Vitamin D Deficiency
Vitamin D deficiency can manifest through several symptoms, many of which are often overlooked or mistaken for other health issues.
Persistent Fatigue
Constant tiredness or low energy levels may be one of the earliest signs of vitamin D deficiency. Even after adequate rest, individuals with low vitamin D levels may continue to feel exhausted.
Vitamin D plays a role in cellular energy production, and insufficient levels may contribute to chronic fatigue.
Bone and Back Pain
One of the most well-known effects of vitamin D deficiency is bone discomfort. Vitamin D helps the body absorb calcium, which is essential for maintaining bone strength.
Low vitamin D levels may cause:
bone pain
lower back pain
increased risk of fractures
Persistent bone discomfort should be evaluated by a healthcare professional.
Muscle Weakness
Vitamin D is important for muscle health and function. Deficiency can lead to muscle weakness, cramps or general muscle fatigue.
Older adults with vitamin D deficiency may also experience reduced mobility and increased risk of falls.
Frequent Illness or Infections
Vitamin D plays a key role in supporting the immune system. Individuals with low vitamin D levels may experience frequent colds, infections or slower recovery from illness.
Research suggests that adequate vitamin D levels help strengthen immune defenses against respiratory infections.
Mood Changes and Depression
Vitamin D may influence brain function and mood regulation. Some studies have found a connection between low vitamin D levels and mood disorders such as depression or anxiety.
People experiencing persistent mood changes should consider evaluating vitamin levels as part of a broader health assessment.
Hair Loss
Severe vitamin D deficiency may contribute to hair thinning or hair loss. While hair loss can have multiple causes, nutritional deficiencies including vitamin D deficiency may play a role.
Slow Wound Healing
Vitamin D contributes to the body’s inflammatory response and tissue repair processes. Individuals with deficiency may notice slower wound healing or delayed recovery from injuries.
Who Is at Risk of Vitamin D Deficiency?
Several factors can increase the risk of vitamin D deficiency.
Limited Sun Exposure
People who spend most of their time indoors or use strong sun protection regularly may not receive enough sunlight to produce sufficient vitamin D.
Urban lifestyles and indoor work environments contribute to this problem.
Older Adults
As people age, the skin becomes less efficient at producing vitamin D from sunlight. Older adults may therefore require additional dietary intake or supplements.
Individuals with Darker Skin
Melanin reduces the skin’s ability to produce vitamin D from sunlight. Individuals with darker skin tones may require longer sun exposure to produce adequate levels.
Poor Dietary Intake
Few foods naturally contain vitamin D. Diets lacking fortified foods, dairy products or fatty fish may contribute to deficiency.
Medical Conditions
Certain medical conditions such as kidney disease, liver disease or digestive disorders can affect vitamin D absorption and metabolism.
How Is Vitamin D Deficiency Diagnosed?
Vitamin D deficiency is diagnosed through a simple blood test that measures the level of 25-hydroxyvitamin D in the bloodstream.
Doctors may recommend testing for individuals who experience symptoms of deficiency or belong to high-risk groups.
Early diagnosis allows healthcare providers to recommend appropriate treatment and lifestyle adjustments.
How to Improve Vitamin D Levels
Sunlight Exposure
Regular sunlight exposure is one of the most effective ways to increase vitamin D levels. Experts generally recommend 10 to 30 minutes of sunlight exposure several times per week, depending on skin type and location.
Dietary Sources of Vitamin D
Although limited, certain foods contain vitamin D, including:
fatty fish such as salmon and mackerel
egg yolks
fortified milk and cereals
mushrooms
Including these foods in the diet can help maintain healthy vitamin D levels.
Vitamin D Supplements
In cases of significant deficiency, doctors may recommend vitamin D supplements. The dosage depends on the individual’s vitamin levels, age and health status.
It is important to take supplements under medical supervision to avoid excessive intake.
Preventing Vitamin D Deficiency
Maintaining adequate vitamin D levels requires a balanced combination of sunlight exposure, proper nutrition and regular health monitoring.
Routine health checkups and vitamin testing can help identify deficiencies early and prevent complications.
Adopting a healthy lifestyle with balanced nutrition and outdoor activity can significantly improve vitamin D status and overall health.
Conclusion
Vitamin D deficiency is a common but often overlooked health concern. Symptoms such as fatigue, bone pain, muscle weakness and frequent infections may indicate low vitamin D levels.
Early detection and proper management are essential to prevent long-term health complications. By ensuring adequate sunlight exposure, maintaining a balanced diet and undergoing regular health checkups, individuals can support healthy vitamin D levels and improve overall wellbeing.
Recognizing the warning signs of vitamin D deficiency and seeking timely medical advice can help protect long-term health and maintain optimal body function.
References
-
Indian Council of Medical Research (ICMR) – Nutritional Deficiency Reports
-
World Health Organization (WHO) – Micronutrient Deficiency Guidelines
-
National Institute of Nutrition (NIN) India – Vitamin D Research Reports
-
Lancet Public Health – Nutritional Health Studies
-
National Institutes of Health (NIH) – Vitamin D Fact Sheets for Health Professionals
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