Call
+918447748545

Published on: Apr 13, 2020
3 minute read
By: Dr Rajan Choudhary

Plasma Treatment For COVID-19?

TREATING COVID WITH BLOOD

We have previously covered proposed treatments for COVID-19, in particular hydroxychloroquine, and explained why we shouldn’t look for a magic cure for this disease. Viruses are difficult to treat, and ultimately supportive treatment appears to be best we can achieve. But an editorial published in BioMedicine Central appears to show a novel treatment for the most ill patients, one that may have flown under most people’s radar.

“A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19”

An interesting title. Lets dissect it.

SUMMARY

- Blood is made up of many different components

- The immune system recognises the virus and produces antibodies against it to neutralise it

- These antibodies float in the blood plasma, a watery solution

- The plasma can be extracted from donated blood, and given to patients suffering from COVID-19

- So far evidence suggests it can help treat the most seriously affected patients.

WHAT IS IN OUR BLOOD

To understand this we must first understand what our blood is made of. Most people know that blood functions to transport oxygen from our lungs. But this is an oversimplification. Blood has many different functions:

- Transport: along with oxygen it transports sugars, fats, protein subunits throughout the body. This is done with the watery PLASMA of the blood.

- Clot: cells and protein structures act to plug any holes that form from cuts and damage. This is done by the PLATELETS in the blood

- Immunity: Immune cells respond to bacteria, viruses, parasites in the blood and body. They target these pathogens, identify and tag them with antibodies, and ultimately destroy them. This is done by the WHITE BLOOD CELLS.

And many more functions that we won’t bore you with.

IMMUNITY

It is this last point that is of interest to us. Our immune system consists of white blood cells that can recognise invading organisms in the blood, around cells and even invaders hiding within our own cells. All cells have protein markers on their surface, no matter if its human cells, bacterial, viral, fungal etc. These markers can be highlighted and targeted by specialised white blood cells, who in turn produce antibodies against these markers. Think of antibodies as handcuffs with flares attached: once attached other white blood cells use this information to find and destroy the invaders.

What is amazing about antibodies is how complex they are. The proteins in our body are incredibly complex. They are long chains that fold into unique shapes depending on hundreds of different types of chemical interactions. These are so complex that supercomputers can take literal years to figure out the shape of a single protein and how it folds depending on the subunits in its chain. This means that our immune system has to recognise these markers and figure out a complementary tag out of hundreds of billions of potential sequences. Antibodies have to be specific to their tag. If an antibody is produced that can target more than one tag, it can cause problems. If it targets a bacterial tag, but accidentally highlights the person’s cells as well, the immune system will start targeting and destroying the person’s organs. These auto-immune disorders can be devastating.

But when they work, antibodies are miraculous. They persist in the blood after an infection, and if a second infection occurs, memory cells in the blood can rapidly produce these antibodies before the infection can even produce symptoms. This is known as immunity, and is why we usually don’t get the same illness twice. Antibody based treatment is see as the future of medical therapy, and is something we will cover in future blogs.

PLASMA EXCHANGE

From population testing we can see that the majority of patients with COVID-19 recover, experiencing either mild symptoms, moderate symptoms requiring some form of treatment and hospitalisation, or no symptoms whatsoever. In these patients their immune system will have successfully recognised the virus and produced antibodies against it to neutralise the virus. It is the patients with severe symptoms, those in which the virus is running rampant in the body, that the production of antibodies happens too late.

Plasma exchange involves obtaining blood from patients who have beaten the virus, spinning the blood to separate out the red cells, white cells, platelets and watery plasma. The plasma contains all the glucose, small proteins and importantly for us, the antibodies. This plasma can be transfused into patients with COVID-19 that cannot cope, in order to help their immune system. These transfused antibodies will neutralise some of the viruses in the patient, reducing the viral load, amount of replication and cell destruction that causes such devastating symptoms in COVID-19.

The published editorial showed that in the most critical pneumonia patients, requiring mechanical ventilators and drugs to support the heart, mortality in plasma exchange patients resulted in a 47.8% mortality instead of 81.3%. Of course it is a single study with a limited number of patients, but the results are encouraging. It is further helped by the fact plasma exchange is a well established therapy, with established protocols known to intensivists and haematologists.

THE FUTURE

We may see the use of Plasma exchange for critically ill patients increase as the pandemic continues. It is not a treatment option available for everyone, as it requires intravenous access and careful monitoring in a controlled setting. But it also needs donation from people who have recovered from COVID and have suitable antibodies. So whilst it might not be a magic pill that everyone expects to cure COVID, it might be the difference between life and death for those that need it most.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

Read Blog

Virtual Clinic India: How SecondMedic Is Transforming Digital Healthcare

Healthcare in India is undergoing a significant transformation as digital platforms reshape how people access medical care. Virtual clinics have emerged as a powerful solution, offering patients immediate access to doctors, diagnostics, prescriptions, and continuous monitoring—without the need for physical hospital visits. This model has become increasingly important in a country where population density, geographical barriers, and long wait times often make healthcare inaccessible or inconvenient.

A virtual clinic uses telemedicine, digital records, online diagnostics, AI tools, and remote monitoring to offer a full healthcare experience through smartphones or computers. SecondMedic is among the leaders in this space, providing a robust virtual clinic ecosystem designed to support preventive health, chronic disease management, and immediate care for everyday medical needs.

The Role of Virtual Clinics in India’s Healthcare Evolution

India faces significant challenges including uneven specialist distribution, crowded hospitals, and rising lifestyle diseases. Virtual clinics bridge these gaps by making healthcare more accessible, affordable, and continuous. They enable patients from metropolitan areas, rural communities, and even remote regions to receive quality care without leaving home.

Key drivers behind virtual clinic growth include:

Growing smartphone and internet penetration
Increased comfort with digital health platforms
The need for safe and convenient care
Rising chronic illnesses requiring ongoing monitoring
Awareness of preventive healthcare

As a result, virtual clinics are becoming the first point of contact for many health concerns.

How Virtual Clinics Deliver Complete Healthcare

Virtual clinics are more than video consultations. They integrate multiple components of healthcare into a unified digital experience. SecondMedic’s virtual clinic model ensures continuity of care by bringing together doctors, diagnostics, monitoring tools, pharmacy support, and digital health records.

Core pillars of virtual clinic care include:

Instant doctor access
Seamless diagnostic testing
AI-based symptom evaluation
E-prescriptions
Medication delivery
Chronic disease monitoring
Preventive health programs

This creates an end-to-end flow that mirrors the experience of visiting a physical clinic, but with added convenience and personalization.

Online Consultations: Immediate Access to Specialists

One of the strongest features of a virtual clinic is the ability to consult qualified doctors quickly. Instead of waiting days for appointments or traveling long distances, patients can connect with specialists through secure video calls or chat.

Virtual consultations are especially useful for:

Common illnesses
Follow-up appointments
Second opinions
Chronic condition management
Mental health support
Elderly care
Pediatric queries

SecondMedic ensures that all consultations are supported by electronic health records, making the experience seamless and informed.

Digital Diagnostics and At-Home Lab Testing

Diagnostics are a core component of healthcare, and virtual clinics have made them significantly more accessible. Users can book lab tests online and have samples collected from their home. Results are delivered digitally, enabling faster diagnosis and treatment.

Advantages of digital diagnostics include:

No travel or waiting lines
Fast report turnaround
Integration with doctor consultations
Easy follow-up and comparisons over time
Better compliance for chronic disease tracking

SecondMedic partners with certified diagnostic labs to ensure high-quality test processing and accurate digital reporting.

Remote Monitoring and Chronic Disease Care

Chronic diseases such as diabetes, hypertension, heart illness, and thyroid disorders require ongoing monitoring. Virtual clinics use connected devices and AI-driven alerts to help patients stay on track with their health goals.

Common remote monitoring tools include:

Glucometers
Blood pressure monitors
Heart-rate trackers
Pulse oximeters
Weight and BMI tools
Sleep monitors
Wearable sensors

SecondMedic uses advanced analytics to detect risk patterns early, send reminders, and support long-term condition management.

E-Prescriptions and Digital Pharmacy Support

Virtual clinics simplify the process of receiving medical prescriptions and ordering medicines. E-prescriptions are accurate, tamper-proof, and instantly shareable with online pharmacies.

Digital pharmacy support helps with:

Medication delivery
Monthly chronic care refills
Transparent drug information
Avoiding prescription errors
Improving medication adherence

SecondMedic integrates e-prescriptions directly with its pharmacy partners, making the treatment process seamless.

Preventive Healthcare Through Virtual Clinics

Preventive care is becoming a priority for many Indians due to rising lifestyle diseases and increasing awareness of early screening. Virtual clinics support this need through personalized health plans designed using AI assessments, digital screenings, and doctor insights.

Preventive healthcare offerings include:

Annual full-body checkups
Lifestyle assessments
Diet and fitness plans
Stress and sleep guidance
Vaccination reminders
Long-term wellness tracking

SecondMedic’s preventive programs are designed to detect risks early and help users adopt healthier habits.

How Virtual Clinics Improve Healthcare Accessibility in India

Virtual clinics remove geographical barriers by bringing medical care to people who otherwise face difficulty accessing doctors. This includes:

Rural regions with limited healthcare facilities
Urban areas with long hospital wait times
Elderly individuals who cannot travel easily
Busy professionals needing flexible care
Patients seeking discretion for sensitive concerns

With increased digital literacy and affordable smartphones, virtual clinics are becoming accessible to a wide demographic.

The Future of Virtual Clinics in India

The future of virtual clinics is strong, supported by national initiatives like the Ayushman Bharat Digital Mission (ABDM), which encourages digital health adoption. AI-driven diagnostics, intelligent triaging, predictive health tools, and integrated hospital systems will further strengthen the virtual care model.

Upcoming trends include:

AI chat-based symptom evaluation
Virtual reality rehabilitation sessions
Smart device-linked monitoring
AI-based early disease detection
Comprehensive preventive health ecosystems
Hybrid care combining virtual and in-clinic visits

SecondMedic is actively developing next-generation virtual clinic technologies to make healthcare more proactive and patient-centered.

Conclusion

Virtual clinics are revolutionizing healthcare delivery in India by offering convenient, reliable, and digitally connected care. They bring together consultations, diagnostics, monitoring, and preventive health in one platform, reducing barriers and enabling patients to receive high-quality medical support anytime, anywhere. SecondMedic leads this transformation with a comprehensive virtual clinic model designed to support long-term health and wellbeing.

To access virtual consultations, digital diagnostics, and remote care services, visit www.secondmedic.com

References

NITI Aayog - Telemedicine and Digital Health Report 2024
Statista - Telehealth Usage India 2025
WHO - Digital Health Standards
IMARC - India Telemedicine Market Forecast
ABDM - Ayushman Bharat Digital Health Guidelines

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.