• Published on: Jul 24, 2024
  • 3 minute read
  • By: SecondMedic Expert

Why Dengue Fever Causes Low Platelet Counts And How To Manage It

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Dengue fever, a mosquito-borne viral infection, has become a significant public health concern in many tropical and subtropical regions. One of the hallmarks of severe dengue is a drop in platelet count, which can lead to serious complications. Understanding why dengue fever causes low platelet counts and how to manage this condition is crucial for anyone living in or traveling to affected areas.

Understanding Dengue Fever

Dengue fever is caused by the dengue virus, which is transmitted primarily by Aedes aegypti mosquitoes. The virus has four distinct serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). Infection with one serotype usually provides lifelong immunity against that specific type, but only partial and temporary immunity against the others. Subsequent infections with a different serotype increase the risk of severe dengue, including dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).

Why Dengue Fever Causes Low Platelet Counts

Platelets are small blood cells that play a crucial role in blood clotting. A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Dengue fever often leads to a significant drop in platelet count, a condition known as thrombocytopenia. There are several reasons for this:

1. Bone Marrow Suppression: The dengue virus can infect and impair the bone marrow, which is responsible for producing blood cells, including platelets. This leads to reduced platelet production.

2. Increased Platelet Destruction: The virus and the immune response it triggers can increase the destruction of platelets. The body’s immune system mistakenly targets platelets, thinking they are infected cells.

3. Increased Utilization: In severe dengue, there is increased leakage of plasma from the blood vessels. To combat this, the body uses up more platelets for clotting, leading to lower counts in the bloodstream.

4. Splenic Sequestration: The spleen may sequester or hold onto more platelets than usual in dengue fever, reducing the number of platelets circulating in the blood.

Symptoms of Low Platelet Count

A low platelet count can lead to several symptoms, which may vary in severity:

- Easy bruising

- Petechiae (small red or purple spots on the skin)

- Bleeding gums or nosebleeds

- Blood in urine or stools

- Heavy menstrual bleeding

- Fatigue and weakness

In severe cases, internal bleeding and shock can occur, which are life-threatening conditions requiring immediate medical attention.

How to Manage Low Platelet Counts in Dengue Fever

Managing low platelet counts in dengue fever involves several strategies aimed at supporting the patient until their body recovers. Here are some key approaches:

1. Hydration

Maintaining adequate hydration is crucial. Fluids help maintain blood volume and support overall bodily functions. Oral rehydration solutions, coconut water, and plain water are often recommended. In severe cases, intravenous (IV) fluids may be necessary.

2. Monitoring Platelet Counts

Regular monitoring of platelet counts is essential to assess the severity of thrombocytopenia. This helps healthcare providers decide on the necessary interventions and monitor recovery.

3. Medications

There are no specific antiviral medications for dengue. However, supportive care includes:

Acetaminophen: To reduce fever and relieve pain. Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin, as they can increase the risk of bleeding.

Platelet Transfusions: In cases of very low platelet counts or significant bleeding, platelet transfusions may be necessary.

4. Rest and Nutrition

Adequate rest and proper nutrition support the body's recovery. A balanced diet rich in fruits, vegetables, and lean proteins can help maintain energy levels and support immune function.

5. Avoiding Certain Foods and Activities

Patients with low platelet counts should avoid activities that can increase the risk of bleeding, such as contact sports. Additionally, foods that may thin the blood, like garlic and ginger, should be consumed in moderation.

6. Natural Remedies

Some natural remedies are believed to help increase platelet counts, although scientific evidence is limited. These include:

Papaya Leaf Extract: Some studies suggest that papaya leaf extract can help increase platelet counts.

Pomegranate and Kiwi: These fruits are rich in vitamins and antioxidants that support overall health.

Preventing Dengue Fever

Preventing dengue fever is the best way to avoid complications like low platelet counts. Preventive measures include:

Mosquito Control: Eliminate standing water around your home, use mosquito repellents, and install screens on windows and doors.

Protective Clothing: Wear long-sleeved shirts, long pants, socks, and shoes when outdoors.

Vaccination: In some regions, a dengue vaccine is available and recommended for individuals who have had a previous dengue infection.

Conclusion

Dengue fever and its complications, such as low platelet counts, pose significant health challenges in many parts of the world. Understanding the reasons behind thrombocytopenia and implementing effective management strategies can help mitigate the risks and support recovery. By taking preventive measures and staying informed, individuals can reduce their risk of dengue fever and its potentially severe consequences.

Read FAQs


A. Dengue fever causes low platelet counts due to bone marrow suppression, increased platelet destruction, increased utilization for clotting, and splenic sequestration. The dengue virus affects the body's ability to produce and maintain adequate platelet levels.

A. Managing low platelet counts involves staying hydrated, monitoring platelet levels, taking acetaminophen for fever and pain, resting, eating a nutritious diet, and avoiding activities and foods that increase bleeding risk. In severe cases, platelet transfusions may be necessary.

A. Signs of a low platelet count include easy bruising, petechiae (small red or purple spots on the skin), bleeding gums or nosebleeds, blood in urine or stools, heavy menstrual bleeding, fatigue, and weakness. In severe cases, internal bleeding and shock may occur.

Read Blog
warning signs of kidney damage

Warning Signs of Kidney Damage: Don’t Ignore These Symptoms

Your kidneys play a vital role in keeping your body healthy. They help filter waste, control blood pressure, balance electrolytes, and produce hormones. But many people don’t realize their kidneys are in trouble until the damage becomes serious. That’s because kidney damage often develops silently, with little to no symptoms in the early stages.

In this blog, we’ll walk you through the warning signs of kidney damage that you should never ignore. Early detection can help protect your kidneys and improve your overall health.

 

Why Are Kidneys So Important?

Before we dive into the warning signs, let’s understand what kidneys do. You have two kidneys located on either side of your spine, just below your rib cage. Each one is about the size of a fist.

Their main functions include:

  • Filtering blood to remove toxins and waste

  • Balancing fluids and electrolytes like sodium, potassium, and calcium

  • Regulating blood pressure

  • Producing hormones for red blood cell production and bone health
     

Because kidneys are so essential, even slight damage can have a big impact on your health.

 

Common Causes of Kidney Damage

Kidney damage can result from a variety of health conditions and lifestyle factors. The most common causes include:

  • High blood pressure (Hypertension)

  • Diabetes (both Type 1 and Type 2)

  • Chronic dehydration

  • Excessive use of painkillers or anti-inflammatory drugs

  • Kidney infections

  • Obstruction from kidney stones or enlarged prostate

  • Autoimmune diseases like lupus
     

Now that we know what can cause kidney damage, let’s explore the early symptoms your body might show.

 

10 Early Warning Signs of Kidney Damage

1. Changes in Urination

Your kidneys are responsible for making urine. So if there’s any change in your urination pattern, it could be a red flag. Watch out for:

  • Frequent urination, especially at night

  • Foamy or bubbly urine

  • Dark-colored or bloody urine

  • Difficulty urinating

  • Decreased urine output
     

These changes can signal that your kidneys are struggling to filter waste properly.

 

2. Swelling in Feet, Ankles, or Hands

Damaged kidneys can’t get rid of extra fluid in your body. This leads to swelling, known as edema, especially in your lower limbs. If your shoes feel tighter or you notice puffiness around your ankles, it’s time to see a doctor.

 

3. Fatigue and Weakness

Healthy kidneys produce a hormone called erythropoietin, which helps make red blood cells. When your kidneys are damaged, you may have fewer red blood cells, leading to anemia. This causes tiredness, weakness, and trouble concentrating.

 

4. Persistent Itching

A buildup of waste in the blood due to kidney issues can cause severe itching, also called uremic pruritus. If you find yourself scratching a lot and over-the-counter creams don’t help, your kidneys could be the problem.

 

5. Shortness of Breath

Excess fluid from kidney dysfunction can build up in your lungs, making it hard to breathe. Also, anemia from kidney disease means your body gets less oxygen, which can leave you feeling breathless with even slight exertion.

 

6. Metallic Taste in the Mouth

A buildup of toxins in your bloodstream can affect your sense of taste. You might notice:

  • A metallic or ammonia-like taste

  • Bad breath

  • Loss of appetite
     

This can eventually lead to unexplained weight loss.

 

7. High Blood Pressure

While high blood pressure can cause kidney damage, it can also be a result of it. Damaged kidneys struggle to regulate blood pressure, leading to a dangerous cycle. If your blood pressure stays high despite medication, kidney function might be to blame.

 

8. Nausea and Vomiting

As waste builds up in your blood, your digestive system can become irritated. This often results in nausea, vomiting, or stomach cramps. If these symptoms become persistent, it’s important to get your kidney function tested.

 

9. Muscle Cramps

Kidney damage can lead to imbalances in minerals like calcium and phosphorus. This can trigger painful muscle cramps, particularly in your legs and back.

 

10. Puffiness Around the Eyes

Protein leaks in urine are often one of the first signs of kidney damage. This may cause puffy eyes, especially in the morning. If you're also feeling fatigued or noticing other symptoms, it could be more than just a lack of sleep.

 

When Should You See a Doctor?

If you notice one or more of the above symptoms, don’t ignore them. A simple blood test and urine test can check your kidney function, and early detection can make a big difference.

You’re especially at risk if:

  • You have diabetes or high blood pressure

  • You have a family history of kidney disease

  • You are over the age of 60

  • You take painkillers frequently

  • You have heart disease
     

 

How to Keep Your Kidneys Healthy

Here are a few tips to protect your kidneys and prevent further damage:

? Stay hydrated
? Control your blood sugar and blood pressure
? Eat a balanced diet low in sodium
? Limit over-the-counter painkillers
? Avoid smoking and excessive alcohol
? Get regular health check-ups

Making small lifestyle changes today can help you avoid serious kidney problems tomorrow.

 

Conclusion

Kidney damage doesn’t happen overnight, and your body often gives early signals that something is wrong. By paying attention to changes like fatigue, swelling, and urinary issues, you can catch the problem early and get the help you need.

Your kidneys are silent workers — until they start failing. So, don’t wait for obvious symptoms. Regular checkups, healthy habits, and awareness of the warning signs of kidney damage can go a long way in protecting your health.

Take care of your kidneys — because once they’re damaged, the effects are hard to reverse.

 

CTA: If you or a loved one are experiencing any of the warning signs of kidney damage, don’t delay — consult a healthcare professional today and get the right diagnosis early.

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