Call
+918447748545

Published on: Nov 13, 2020
1 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Using The Cellular Handshake Against The Virus

Using the cellular handshake against the virus

In early November an interesting study was published in The Lancet Respiratory Medicine, describing the treatment of a severe COVID-19 patient with human recombinant soluble angiotensin-converting enzyme-2. By using the treatment, it was possible to see the disappearance of the virus swiftly from the patient's serum, nose, and lungs, as well as a reduction in the patients’ inflammatory markers. How was this achieved? And why is this so intriguing.

When we look at treating viruses, there are several strategies at work. You can prevent its spread by the use of social distancing or masks, you can use medications that prevent its replication (such as Tamiflu). Or you can stop the virus from entering the cells, the first step in viral replication.

SARS-CoV-2 appears to enter human cells through the ACE2 receptor. ACE2 is a protein in the cell membrane found across the human body, especially the lungs, heart, kidney and small intestine. It function is related to the Renin-Angiotensin System, a mechanism by which the kidneys control your blood pressure.

Angiotensin-Converting Enzyme converts angiotensin 1 to angiotensin 2, a hormone that causes blood vessels to constrict. ACE 2 instead converts it to a protein that causes dilation of blood vessels. This likely protects these critical organs and ensure they receive sufficient blood to perform their tasks. ACE2 is being investigated as a possible target for blood pressure medications.

The study used a genetically modified soluble form of ACE2 that mimics the protein found on human cell membranes. By increasing its availability in the blood, the SARS-CoV-2 virus binds to this protein, resulting in its inactivation, rather than entering lung cells and causing lung injury. Lab studies have shown that it can reduce viral growth by as much as 1000 to 5000 times, and phase 1 studies show it to be safe to use in people.

The actual described case was in a 45-year-old woman, hospitalized with COVID, suffering from severe shortness of breath, cough and fatigue. She was first treated with hydroxychloroquine and anticoagulants, but this proved ineffective, and the virus was causing increasing damage to her lungs. Nine days after her symptoms started, she received the ACE2 treatment for a week, with no side effects. This resulted in an increase in ACE2 activity (seen from her blood results), but also a marked decrease in multiple inflammatory markers associated with COVID-19, as well as a sharp decrease in COVID 19 numbers. Indeed, the viral load dropped from 32,000 per mL to just 270 per mL two days after treatment started. She was also able to produce antibodies against the virus, so this did not impair her from getting immunity.

It is certainly a very interesting case, though questions remain on how feasible it would be (as well as how expensive) to manufacture large quantities of this protein receptor for treatment use, as well as how it fairs in clinical trials.

Read Blog

Telemedicine Platform Comparison India: Evaluating the Best Digital Healthcare Providers

Telemedicine has transformed the healthcare landscape in India by making medical services more accessible, affordable, and patient-friendly. With growing smartphone usage, improved internet penetration, and digital health adoption under the Ayushman Bharat Digital Mission (ABDM), teleconsultation platforms have become a primary mode of healthcare for millions. But with multiple platforms available, choosing the right one requires a proper telemedicine platform comparison India.

This blog provides a detailed comparison of India’s leading telemedicine providers and evaluates what sets SecondMedic apart in terms of accessibility, specialist availability, user experience, and overall digital healthcare value.

Why Telemedicine Is Growing Rapidly in India

The demand for digital healthcare platforms is driven by:

Busy lifestyles limiting hospital visits
Rising chronic diseases needing follow-ups
Rural populations needing specialist access
Post-pandemic digital health acceptance
Cost efficiency
Faster access to care

According to Statista, the telemedicine market size in India is increasing significantly, driven by digital transformation and patient willingness to adopt virtual care.

Key Parameters for Comparing Telemedicine Platforms

When comparing telemedicine platforms, users should evaluate the following:

1. Doctor Availability

The range of specialists available-cardiology, dermatology, pediatrics, gynecology, orthopedics, etc.-is crucial.

2. Pricing and Consultation Fees

Costs vary significantly between platforms. Affordable, transparent pricing determines long-term usability.

3. User Interface (UI/UX)

The platform must be easy to navigate, especially for elderly patients.

4. Appointment Wait Time

Faster access to doctors enhances the value of telemedicine.

5. E-Prescriptions

Availability of legal, digital prescriptions is essential for seamless continuity of care.

6. Electronic Health Records (EHR)

Platforms offering unified records improve patient experience.

7. Service Range

A good telemedicine platform should provide:

Teleconsultations
Second opinions
Remote monitoring
Home diagnostics
Preventive health packages

SecondMedic is one of the few platforms offering this full ecosystem.

Comparison of Major Telemedicine Platforms in India

1. SecondMedic

Specialties: Full range including cardiology, dermatology, neurology
Strengths:

Instant teleconsultation
Online specialist access
Remote monitoring tools
Second opinion services
Preventive health packages
Strong chronic care management
Patient-first experience
Easy EHR access
Best For: Those wanting comprehensive digital healthcare

2. Practo

Strengths:

Wide doctor network
Pharmacy integration
Lab test bookings
Limitations:
Higher consultation fees
Variable doctor response times

3. Apollo 24/7

Strengths:

Strong specialist network
Integration with Apollo hospitals
Limitations:
High cost
Limited remote monitoring features

4. Tata 1mg

Strengths:

Affordable consultations
Pharmacy + lab tests
Limitations:
Limited specialist variety
Heavy focus on diagnostics and medicines rather than telemedicine

5. MFine

Strengths:

Good specialist availability
Partner-hospital model
Limitations:
Service coverage varies
Less personalized care

This comparison shows that while multiple telemedicine platforms serve specific needs, SecondMedic provides a more integrated healthcare experience connecting consultations, preventive care, and chronic disease management.

What Makes SecondMedic Stand Out

1. Comprehensive Specialty Coverage

From general physicians to cardiologists, dermatologists, neurologists, endocrinologists, and pediatricians, SecondMedic covers major medical specialties.

2. Strong Chronic Disease Management

Continuous monitoring and scheduled check-ins help manage long-term conditions effectively.

3. Online Second Opinions

Patients needing specialist reassessment benefit from high-quality second opinions from top doctors.

4. Remote Monitoring Ecosystem

Compatible with digital ECGs, glucometers, BP monitors, and other wearable tools.

5. Affordable and Transparent Pricing

SecondMedic offers cost-effective consultations without hidden charges.

6. Easy-to-Use Interface

Designed for all age groups with minimal complexity.

7. Integration with Preventive Health Packages

Users can also book diagnostics, screenings, and wellness plans.

Importance of EHR in Telemedicine Platform Comparison India

Electronic Health Records improve:

Safety
Accuracy
Convenience
Treatment continuity

SecondMedic’s EHR system is aligned with ABDM guidelines, making health data secure and portable.

User Experience and Accessibility

A good telemedicine platform must offer:

Multilingual support
Low-bandwidth compatibility
Easy appointment scheduling
Quick report upload

SecondMedic excels in offering a smooth, user-friendly experience.

Future of Telemedicine Platforms in India

The next evolution includes:

AI-assisted triage
Wearable tech integration
Predictive health alerts
Virtual healthcare kiosks
Full ABDM interoperability

SecondMedic is aligning with these innovations to build the next-generation digital healthcare ecosystem.

Conclusion

Telemedicine platform comparison India reveals that while several platforms offer strong digital health services, SecondMedic stands out due to its integrated care model, specialist availability, chronic disease support, remote monitoring tools, and preventive healthcare programs. For patients seeking a complete, reliable, and patient-centric telemedicine experience, SecondMedic remains a top choice.

To explore telemedicine services, visit www.secondmedic.com

References

NITI Aayog - Telemedicine guidelines for India
Statista - Telemedicine adoption and market size
ABDM - Digital health mission framework
WHO - Teleconsultation standards
IMARC - Digital health ecosystem growth
SecondMedic platform insights

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.