Q. Why do adverse reactions to vaccinations cause armpit lumps?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Localized armpit lumps can sometimes occur after receiving a vaccine, and these are known as "injection site reactions." These reactions are caused by the body's immune system trying to protect itself against foreign substances that have been injected into the body.
When it comes to vaccinations, the body is exposed to antigens which can cause an immune response. The most common antigen found in vaccines is called “squalene”, which stimulates T-cells in your immune system and causes a localized reaction - often forming hard lumps at the injection site. This lump may be painful and tender, but it should resolve within a few days as your body clears out any remaining antigens; however, if you experience extreme pain or swelling that lasts for more than 3 days you should contact your doctor.
In addition to squalene-induced armpit lumps, some people may also experience delayed allergic reactions up to several weeks after vaccination due to an overactive immune response stimulating a wide range of antibodies that could cause inflammation throughout the body. If this occurs with your vaccination then again contact your doctor so they can take appropriate action.
Taken together these two instances demonstrate why adverse reactions from vaccinations can sometimes manifest in form of armpit lumps – something that many people need to be aware of before they consider undergoing immunization against infectious diseases like influenza or measles/mumps/rubella (MMR).
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