What common drugs do not mix well with heart medications?

The most common drugs that should not be mixed with heart medications are nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen. These increase the risk of stomach ulcers, bleeding, and kidney problems when taken in combination with certain heart medications such as ACE inhibitors, ARBs, beta-blockers, statins and warfarin. Additionally, some antidepressants such as tricyclic antidepressants can also interact negatively with heart medications by increasing one’s risk of having a stroke or developing arrhythmias. Other drug interactions to watch out for include taking stimulants like amphetamines or cough/cold medicines that contain pseudoephedrine while on certain types of heart medication due to the potential for sudden changes in blood pressure or dangerous irregular heartbeat patterns. It is important to discuss any other prescription drugs and over-the-counter medicines you are taking with your doctor before taking any new medication prescribed for your heart health.