Q. What are liver function tests (LFT), and why are they performed?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Liver function tests (LFT) are a group of blood tests that assess the health and function of the liver. These tests provide valuable information about how well the liver is working and can help diagnose liver diseases or monitor existing conditions.
LFTs typically measure various substances in the blood that are produced by the liver or affected by liver function. Common markers include enzymes like ALT (alanine transaminase) and AST (aspartate transaminase), as well as bilirubin, albumin, and alkaline phosphatase.
ALT and AST are enzymes found within liver cells. Elevated levels in the blood may indicate liver damage or inflammation, often seen in conditions like hepatitis or fatty liver disease. Bilirubin, a waste product from the breakdown of red blood cells, can indicate problems if levels are too high, suggesting liver or bile duct issues.
Albumin is a protein made by the liver that helps maintain blood volume and regulate pressure. Low albumin levels can indicate liver disease. Alkaline phosphatase is an enzyme found in bile ducts; elevated levels may suggest bile flow problems or bone disease.
Liver function tests are performed for several reasons. They are used to detect liver diseases like hepatitis, cirrhosis, or fatty liver disease. LFTs also help monitor the progression of liver conditions and evaluate the effectiveness of treatments.
Additionally, liver function tests may be ordered if a person shows symptoms of liver disease, such as jaundice (yellowing of the skin and eyes), abdominal pain, nausea, or fatigue. They are also part of routine check-ups for individuals at risk of liver problems, such as those with a history of alcohol abuse, obesity, or certain medical conditions.
In summary, liver function tests (LFT) are important diagnostic tools that provide crucial insights into liver health. By measuring specific markers in the blood, LFTs help identify liver diseases, monitor ongoing conditions, and guide treatment decisions, ultimately contributing to better liver care and overall health.
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