Q.

Is vitiligo genetically transmitted disease?

Asked by KAVITA MISHRA ·

Medically reviewed by SecondMedic medical review team

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Answered by SecondMedic Expert

Dermatologist · Dermatology

Yes, vitiligo is a genetically transmitted disease. However, its exact cause is not yet known.

Vitiligo occurs when melanocytes (pigment-producing cells) are destroyed in certain areas of the skin, resulting in patches of discoloured or completely depigmented skin. This destruction can occur as a result of an autoimmune response—a mechanism by which the body’s immune system mistakenly attacks healthy cells—or as a result of genetic inheritance. In fact, studies have suggested that up to 40% of those with vitiligo have at least one family member who has also been diagnosed with it.

The genetic component underlying some instances of vitiligo is believed to be complex and multifactorial – meaning it involves many different genes from different locations on multiple chromosomes within our DNA — however no definitive gene or combination of genes has been identified yet as responsible for causing this condition . That’s why more research still needs to be conducted into understanding how exactly genetics may play a role in the transmission and development of this disorder.

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